SREB2/GPR85, a schizophrenia risk factor, negatively regulates hippocampal adult neurogenesis and neurogenesis-dependent learning and memory

European Journal of Neuroscience

Volumn 36, Issue 5, 2012, Pages 2597-2608

  Chen, Qian ^a   Kogan, Jeffrey H ^a   Gross, Adam K ^a   Zhou, Yuan ^b   Walton, Noah M ^a   Shin, Rick ^a   Heusner, Carrie L ^a   Miyake, Shinichi ^a   Tajinda, Katsunori ^a   Tamura, Kouichi ^a   Matsumoto, Mitsuyuki ^a  

^a ASTELLAS PHARMA GLOBAL DEVELOPMENT   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Bromodeoxyuridine; Cognition; Dentate gyrus; Mutant mouse; Psychiatric disease

Indexed keywords

BROXURIDINE; DOUBLECORTIN; G PROTEIN COUPLED RECEPTOR; SUPER CONSERVED RECEPTOR EXPRESSED IN BRAIN 2 PROTEIN; UNCLASSIFIED DRUG;

ADULT ANIMAL; ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; DENDRITE; DENTATE GYRUS; HIPPOCAMPUS; HUMAN; IMMUNOHISTOCHEMISTRY; LEARNING; MAZE TEST; MEMORY; MENTAL TASK; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ASSAY; RISK FACTOR; SCHIZOPHRENIA; SPATIAL DISCRIMINATION; TASK PERFORMANCE; TRANSGENIC MOUSE; WORKING MEMORY;

ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; HIPPOCAMPUS; LEARNING; MEMORY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUROGENESIS; NEURONS; RECEPTORS, G-PROTEIN-COUPLED; RISK FACTORS; SCHIZOPHRENIA;

EID: 84865865918     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2012.08180.x     Document Type: Article

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