-
1
-
-
33645097407
-
Dependence of nelfinavir brain uptake on dose and tissue concentrations of the selective P-glycoprotein inhibitor zosuquidar in rats
-
Anderson BD, May MJ, Jordan S, Song L, Roberts MJ, Leggas M. Dependence of nelfinavir brain uptake on dose and tissue concentrations of the selective P-glycoprotein inhibitor zosuquidar in rats. Drug Metab Dispos 2006; 34: 653-659
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 653-659
-
-
Anderson, B.D.1
May, M.J.2
Jordan, S.3
Song, L.4
Roberts, M.J.5
Leggas, M.6
-
2
-
-
0036355399
-
Reversal of multidrug resistance: Lessons from clinical oncology
-
discussion 96-102, 180-105
-
Bates SF, Chen C, Robey R, Kang M, Figg WD, Fojo T. Reversal of multidrug resistance: lessons from clinical oncology. Novartis Found Symp 2002; 243: 83-96; discussion 96-102, 180-105
-
(2002)
Novartis Found Symp
, vol.243
, pp. 83-96
-
-
Bates, S.F.1
Chen, C.2
Robey, R.3
Kang, M.4
Figg, W.D.5
Fojo, T.6
-
3
-
-
0038675082
-
A population pharmacokinetic model for paclitaxel in the presence of a novel P-gp modulator, Zosuquidar Trihydrochloride (LY335979
-
Callies S, de Alwis DP, Harris A, Vasey P, Beijnen JH, Schellens JH, Burgess M, Aarons L A population pharmacokinetic model for paclitaxel in the presence of a novel P-gp modulator, Zosuquidar Trihydrochloride (LY335979). Br J Clin Pharmacol 2003; 56: 46-56
-
(2003)
Br J Clin Pharmacol
, vol.56
, pp. 46-56
-
-
Callies, S.1
De Alwis, D.P.2
Harris, A.3
Vasey, P.4
Beijnen, J.H.5
Schellens, J.H.6
Burgess, M.7
Aarons, L.8
-
4
-
-
0037330465
-
A population pharmacokinetic model for doxorubicin and doxorubicinol in the presence of a novel MDR modulator, zosuquidar trihydrochloride (LY335979
-
Callies S, de Alwis DP, Wright JG, Sandler A, Burgess M, Aarons L A population pharmacokinetic model for doxorubicin and doxorubicinol in the presence of a novel MDR modulator, zosuquidar trihydrochloride (LY335979). Cancer Chemother Pharmacol 2003; 51: 107-118
-
(2003)
Cancer Chemother Pharmacol
, vol.51
, pp. 107-118
-
-
Callies, S.1
De Alwis, D.P.2
Wright, J.G.3
Sandler, A.4
Burgess, M.5
Aarons, L.6
-
5
-
-
0035030729
-
Reversal of multidrug resistance by the P-glycoprotein modulator, LY335979, from the bench to the clinic
-
Dantzig AH, Law KL, Cao J, Starling JJ. Reversal of multidrug resistance by the P-glycoprotein modulator, LY335979, from the bench to the clinic. Curr Med Chem 2001; 8: 39-50
-
(2001)
Curr Med Chem
, vol.8
, pp. 39-50
-
-
Dantzig, A.H.1
Law, K.L.2
Cao, J.3
Starling, J.J.4
-
6
-
-
84906841258
-
P-glycoprotein inhibition promotes prednisone retention in human sinonasal polyp explants
-
Kocharyan A, Feldman R, Singleton A, Han X, Bleier BS. P-glycoprotein inhibition promotes prednisone retention in human sinonasal polyp explants. Int Forum Allergy Rhinol 2014; 4: 734-738
-
(2014)
Int Forum Allergy Rhinol
, vol.4
, pp. 734-738
-
-
Kocharyan, A.1
Feldman, R.2
Singleton, A.3
Han, X.4
Bleier, B.S.5
-
7
-
-
84930485524
-
Itraconazole and clarithromycin inhibit P-glycoprotein activity in primary human sinonasal epithelial cells
-
Lam A, Hoang JD, Singleton A, Han X, Bleier BS. Itraconazole and clarithromycin inhibit P-glycoprotein activity in primary human sinonasal epithelial cells. Int Forum Allergy Rhinol 2015; 5: 477-480
-
(2015)
Int Forum Allergy Rhinol
, vol.5
, pp. 477-480
-
-
Lam, A.1
Hoang, J.D.2
Singleton, A.3
Han, X.4
Bleier, B.S.5
-
8
-
-
4744375978
-
New insights into drug absorption: Studies with sirolimus
-
Paine MF, Leung LY, Watkins PB. New insights into drug absorption: studies with sirolimus. Ther Drug Monit 2004; 26: 463-467
-
(2004)
Ther Drug Monit
, vol.26
, pp. 463-467
-
-
Paine, M.F.1
Leung, L.Y.2
Watkins, P.B.3
-
9
-
-
5744228959
-
Modulation of drug resistance transporters as a strategy for treating myelodysplastic syndrome
-
Ross DD. Modulation of drug resistance transporters as a strategy for treating myelodysplastic syndrome. Best Pract Res Clin Haematol 2004; 17: 641-651
-
(2004)
Best Pract Res Clin Haematol
, vol.17
, pp. 641-651
-
-
Ross, D.D.1
-
10
-
-
0037358040
-
Overcoming multidrug resistance in cancer: An update on the clinical strategy of inhibiting p-glycoprotein
-
Thomas H, Coley HM. Overcoming multidrug resistance in cancer: an update on the clinical strategy of inhibiting p-glycoprotein. Cancer Control 2003; 10: 159-165
-
(2003)
Cancer Control
, vol.10
, pp. 159-165
-
-
Thomas, H.1
Coley, H.M.2
-
12
-
-
84863983999
-
Zosuquidar and an albumin-binding prodrug of zosuquidar reverse multidrug resistance in breast cancer cells of doxorubicin and an albumin-binding prodrug of doxorubicin
-
Abu Ajaj K, Graeser R, Kratz F. Zosuquidar and an albumin-binding prodrug of zosuquidar reverse multidrug resistance in breast cancer cells of doxorubicin and an albumin-binding prodrug of doxorubicin. Breast Cancer Res Treat 2012; 134: 117-129
-
(2012)
Breast Cancer Res Treat
, vol.134
, pp. 117-129
-
-
Abu Ajaj, K.1
Graeser, R.2
Kratz, F.3
-
13
-
-
33748892510
-
Metabolism of ATP-binding cassette drug transporter inhibitors: Complicating factor for multidrug resistance
-
Cnubben NH, Wortelboer HM, van Zanden JJ, Rietjens IM, van Bladeren PJ. Metabolism of ATP-binding cassette drug transporter inhibitors: complicating factor for multidrug resistance. Expert Opin Drug Metab Toxicol 2005; 1: 219-232
-
(2005)
Expert Opin Drug Metab Toxicol
, vol.1
, pp. 219-232
-
-
Cnubben, N.H.1
Wortelboer, H.M.2
Van Zanden, J.J.3
Rietjens, I.M.4
Van Bladeren, P.J.5
-
14
-
-
78549238612
-
Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: A randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999
-
Cripe LD, Uno H, Paietta EM, Litzow MR, Ketterling RP, Bennett JM, Rowe JM, Lazarus HM, Luger S, Tallman MS. Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999. Blood 2010; 116: 4077-4085
-
(2010)
Blood
, vol.116
, pp. 4077-4085
-
-
Cripe, L.D.1
Uno, H.2
Paietta, E.M.3
Litzow, M.R.4
Ketterling, R.P.5
Bennett, J.M.6
Rowe, J.M.7
Lazarus, H.M.8
Luger, S.9
Tallman, M.S.10
-
15
-
-
8444251671
-
Phase i study of docetaxel in combination with the P-glycoprotein inhibitor, zosuquidar, in resistant malignancies
-
Fracasso PM, Goldstein LJ, de Alwis DP, Rader JS, Arquette MA, Goodner SA, Wright LP, Fears CL, Gazak RJ, Andre VA, Burgess MF, Slapak CA, Schellens JH. Phase I study of docetaxel in combination with the P-glycoprotein inhibitor, zosuquidar, in resistant malignancies. Clin Cancer Res 2004; 10: 7220-7228
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7220-7228
-
-
Fracasso, P.M.1
Goldstein, L.J.2
De Alwis, D.P.3
Rader, J.S.4
Arquette, M.A.5
Goodner, S.A.6
Wright, L.P.7
Fears, C.L.8
Gazak, R.J.9
Andre, V.A.10
Burgess, M.F.11
Slapak, C.A.12
Schellens, J.H.13
-
16
-
-
3242781758
-
Clinical effects and P-glycoprotein inhibition in patients with acute myeloid leukemia treated with zosuquidar trihydrochloride, daunorubicin and cytarabine
-
Gerrard G, Payne E, Baker RJ, Jones DT, Potter M, Prentice HG, Ethell M, McCullough H, Burgess M, Mehta AB, Ganeshaguru K. Clinical effects and P-glycoprotein inhibition in patients with acute myeloid leukemia treated with zosuquidar trihydrochloride, daunorubicin and cytarabine. Haematologica 2004; 89: 782-790
-
(2004)
Haematologica
, vol.89
, pp. 782-790
-
-
Gerrard, G.1
Payne, E.2
Baker, R.J.3
Jones, D.T.4
Potter, M.5
Prentice, H.G.6
Ethell, M.7
McCullough, H.8
Burgess, M.9
Mehta, A.B.10
Ganeshaguru, K.11
-
17
-
-
67349183943
-
A phase i trial of continuous infusion of the multidrug resistance inhibitor zosuquidar with daunorubicin and cytarabine in acute myeloid leukemia
-
Lancet JE, Baer MR, Duran GE, List AF, Fielding R, Marcelletti JF, Multani PS, Sikic BI A phase I trial of continuous infusion of the multidrug resistance inhibitor zosuquidar with daunorubicin and cytarabine in acute myeloid leukemia. Leuk Res 2009; 33: 1055-1061
-
(2009)
Leuk Res
, vol.33
, pp. 1055-1061
-
-
Lancet, J.E.1
Baer, M.R.2
Duran, G.E.3
List, A.F.4
Fielding, R.5
Marcelletti, J.F.6
Multani, P.S.7
Sikic, B.I.8
-
18
-
-
21244504196
-
Phase i study of the multidrug resistance inhibitor zosuquidar administered in combination with vinorelbine in patients with advanced solid tumours
-
Le LH, Moore MJ, Siu LL, Oza AM, MacLean M, Fisher B, Chaudhary A, de Alwis DP, Slapak C, Seymour L. Phase I study of the multidrug resistance inhibitor zosuquidar administered in combination with vinorelbine in patients with advanced solid tumours. Cancer Chemother Pharmacol 2005; 56: 154-160
-
(2005)
Cancer Chemother Pharmacol
, vol.56
, pp. 154-160
-
-
Le, L.H.1
Moore, M.J.2
Siu, L.L.3
Oza, A.M.4
MacLean, M.5
Fisher, B.6
Chaudhary, A.7
De Alwis, D.P.8
Slapak, C.9
Seymour, L.10
-
19
-
-
63349111030
-
Leukemic blast and natural killer cell P-glycoprotein function and inhibition in a clinical trial of zosuquidar infusion in acute myeloid leukemia
-
Marcelletti JF, Multani PS, Lancet JE, Baer MR, Sikic BI. Leukemic blast and natural killer cell P-glycoprotein function and inhibition in a clinical trial of zosuquidar infusion in acute myeloid leukemia. Leuk Res 2009; 33: 769-774
-
(2009)
Leuk Res
, vol.33
, pp. 769-774
-
-
Marcelletti, J.F.1
Multani, P.S.2
Lancet, J.E.3
Baer, M.R.4
Sikic, B.I.5
-
20
-
-
34247213414
-
Phase I/II trial of a P-glycoprotein inhibitor, Zosuquidar.3HCl trihydrochloride (LY335979), given orally in combination with the CHOP regimen in patients with non-Hodgkin's lymphoma
-
Morschhauser F, Zinzani PL, Burgess M, Sloots L, Bouafia F, Dumontet C. Phase I/II trial of a P-glycoprotein inhibitor, Zosuquidar.3HCl trihydrochloride (LY335979), given orally in combination with the CHOP regimen in patients with non-Hodgkin's lymphoma. Leuk Lymphoma 2007; 48: 708-715
-
(2007)
Leuk Lymphoma
, vol.48
, pp. 708-715
-
-
Morschhauser, F.1
Zinzani, P.L.2
Burgess, M.3
Sloots, L.4
Bouafia, F.5
Dumontet, C.6
-
21
-
-
33745746815
-
Pharmacological strategies for overcoming multidrug resistance
-
Nobili S, Landini I, Giglioni B, Mini E. Pharmacological strategies for overcoming multidrug resistance. Curr Drug Targets 2006; 7: 861-879
-
(2006)
Curr Drug Targets
, vol.7
, pp. 861-879
-
-
Nobili, S.1
Landini, I.2
Giglioni, B.3
Mini, E.4
-
22
-
-
79951530814
-
Novel and emerging drugs for acute myeloid leukemia: Pharmacology and therapeutic activity
-
Robak T, Szmigielska-Kaplon A, Pluta A, Grzybowska-Izydorczyk O, Wolska A, Czemerska M, Wierzbowska A. Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity. Curr Med Chem 2011; 18: 638-666
-
(2011)
Curr Med Chem
, vol.18
, pp. 638-666
-
-
Robak, T.1
Szmigielska-Kaplon, A.2
Pluta, A.3
Grzybowska-Izydorczyk, O.4
Wolska, A.5
Czemerska, M.6
Wierzbowska, A.7
-
23
-
-
0036895024
-
A phase i trial of a potent P-glycoprotein inhibitor, Zosuquidar.3HCl trihydrochloride (LY335979), administered orally in combination with doxorubicin in patients with advanced malignancies
-
Rubin EH, de Alwis DP, Pouliquen I, Green L, Marder P, Lin Y, Musanti R, Grospe SL, Smith SL, Toppmeyer DL, Much J, Kane M, Chaudhary A, Jordan C, Burgess M, Slapak CA A phase I trial of a potent P-glycoprotein inhibitor, Zosuquidar.3HCl trihydrochloride (LY335979), administered orally in combination with doxorubicin in patients with advanced malignancies. Clin Cancer Res 2002; 8: 3710-3717
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3710-3717
-
-
Rubin, E.H.1
De Alwis, D.P.2
Pouliquen, I.3
Green, L.4
Marder, P.5
Lin, Y.6
Musanti, R.7
Grospe, S.L.8
Smith, S.L.9
Toppmeyer, D.L.10
Much, J.11
Kane, M.12
Chaudhary, A.13
Jordan, C.14
Burgess, M.15
Slapak, C.A.16
-
24
-
-
68149149796
-
A randomized, placebo-controlled, double-blind phase 2 study of docetaxel compared to docetaxel plus zosuquidar (LY335979) in women with metastatic or locally recurrent breast cancer who have received one prior chemotherapy regimen
-
Ruff P, Vorobiof DA, Jordaan JP, Demetriou GS, Moodley SD, Nosworthy AL, Werner ID, Raats J, Burgess LJ A randomized, placebo-controlled, double-blind phase 2 study of docetaxel compared to docetaxel plus zosuquidar (LY335979) in women with metastatic or locally recurrent breast cancer who have received one prior chemotherapy regimen. Cancer Chemother Pharmacol 2009; 64: 763-768
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, pp. 763-768
-
-
Ruff, P.1
Vorobiof, D.A.2
Jordaan, J.P.3
Demetriou, G.S.4
Moodley, S.D.5
Nosworthy, A.L.6
Werner, I.D.7
Raats, J.8
Burgess, L.J.9
-
25
-
-
2542479863
-
A Phase i trial of a potent P-glycoprotein inhibitor, zosuquidar trihydrochloride (LY335979), administered intravenously in combination with doxorubicin in patients with advanced malignancy
-
Sandler A, Gordon M, De Alwis DP, Pouliquen I, Green L, Marder P, Chaudhary A, Fife K, Battiato L, Sweeney C, Jordan C, Burgess M, Slapak CA A Phase I trial of a potent P-glycoprotein inhibitor, zosuquidar trihydrochloride (LY335979), administered intravenously in combination with doxorubicin in patients with advanced malignancy. Clin Cancer Res 2004; 10: 3265-3272
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3265-3272
-
-
Sandler, A.1
Gordon, M.2
De Alwis, D.P.3
Pouliquen, I.4
Green, L.5
Marder, P.6
Chaudhary, A.7
Fife, K.8
Battiato, L.9
Sweeney, C.10
Jordan, C.11
Burgess, M.12
Slapak, C.A.13
-
26
-
-
40349095136
-
Zosuquidar restores drug sensitivity in P-glycoprotein expressing acute myeloid leukemia (AML
-
Tang R, Faussat AM, Perrot JY, Marjanovic Z, Cohen S, Storme T, Morjani H, Legrand O, Marie JP. Zosuquidar restores drug sensitivity in P-glycoprotein expressing acute myeloid leukemia (AML). BMC Cancer 2008; 8: 51
-
(2008)
BMC Cancer
, vol.8
, pp. 51
-
-
Tang, R.1
Faussat, A.M.2
Perrot, J.Y.3
Marjanovic, Z.4
Cohen, S.5
Storme, T.6
Morjani, H.7
Legrand, O.8
Marie, J.P.9
-
27
-
-
34250163664
-
Modulation of the brain distribution of imatinib and its metabolites in mice by valspodar, zosuquidar and elacridar
-
Bihorel S, Camenisch G, Lemaire M, Scherrmann JM. Modulation of the brain distribution of imatinib and its metabolites in mice by valspodar, zosuquidar and elacridar. Pharm Res 2007; 24: 1720-1728
-
(2007)
Pharm Res
, vol.24
, pp. 1720-1728
-
-
Bihorel, S.1
Camenisch, G.2
Lemaire, M.3
Scherrmann, J.M.4
-
28
-
-
33845300239
-
Role of drug efflux carriers in the healthy and diseased brain
-
Hermann DM, Kilic E, Spudich A, Kramer SD, Wunderli-Allenspach H, Bassetti CL. Role of drug efflux carriers in the healthy and diseased brain. Ann Neurol 2006; 60: 489-498
-
(2006)
Ann Neurol
, vol.60
, pp. 489-498
-
-
Hermann, D.M.1
Kilic, E.2
Spudich, A.3
Kramer, S.D.4
Wunderli-Allenspach, H.5
Bassetti, C.L.6
-
29
-
-
0442313667
-
The influence of the P-glycoprotein inhibitor zosuquidar trihydrochloride (LY335979) on the brain penetration of paclitaxel in mice
-
Kemper EM, Cleypool C, Boogerd W, Beijnen JH, van Tellingen O. The influence of the P-glycoprotein inhibitor zosuquidar trihydrochloride (LY335979) on the brain penetration of paclitaxel in mice. Cancer Chemother Pharmacol 2004; 53: 173-178
-
(2004)
Cancer Chemother Pharmacol
, vol.53
, pp. 173-178
-
-
Kemper, E.M.1
Cleypool, C.2
Boogerd, W.3
Beijnen, J.H.4
Van Tellingen, O.5
-
30
-
-
84873050654
-
Analysis of the inhibition potential of zosuquidar derivatives on selected bacterial and fungal ABC transporters
-
Infed N, Smits SH, Dittrich T, Braun M, Driessen AJ, Hanekop N, Schmitt L. Analysis of the inhibition potential of zosuquidar derivatives on selected bacterial and fungal ABC transporters. Mol Membr Biol 2013; 30: 217-227
-
(2013)
Mol Membr Biol
, vol.30
, pp. 217-227
-
-
Infed, N.1
Smits, S.H.2
Dittrich, T.3
Braun, M.4
Driessen, A.J.5
Hanekop, N.6
Schmitt, L.7
-
31
-
-
0032980591
-
Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents
-
Lehne G, De Angelis P, den Boer M, Rugstad HE. Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents. Leukemia 1999; 13: 768-778
-
(1999)
Leukemia
, vol.13
, pp. 768-778
-
-
Lehne, G.1
De Angelis, P.2
Den Boer, M.3
Rugstad, H.E.4
-
32
-
-
67650733509
-
P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients
-
Tang R, Cohen S, Perrot JY, Faussat AM, Zuany-Amorim C, Marjanovic Z, Morjani H, Fava F, Corre E, Legrand O, Marie JP. P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients. BMC Cancer 2009; 9: 199
-
(2009)
BMC Cancer
, vol.9
, pp. 199
-
-
Tang, R.1
Cohen, S.2
Perrot, J.Y.3
Faussat, A.M.4
Zuany-Amorim, C.5
Marjanovic, Z.6
Morjani, H.7
Fava, F.8
Corre, E.9
Legrand, O.10
Marie, J.P.11
-
33
-
-
0242426629
-
Role of Ca2+-Activated K+ channels in human erythrocyte apoptosis
-
Lang PA, Kaiser S, Myssina S, Wieder T, Lang F, Huber SM. Role of Ca2+-Activated K+ channels in human erythrocyte apoptosis. Am J Physiol Cell Physiol 2003; 285: C1553-C1560
-
(2003)
Am J Physiol Cell Physiol
, vol.285
, pp. C1553-C1560
-
-
Lang, P.A.1
Kaiser, S.2
Myssina, S.3
Wieder, T.4
Lang, F.5
Huber, S.M.6
-
35
-
-
67349183943
-
A phase i trial of continuous infusion of the multidrug resistance inhibitor zosuquidar with daunorubicin and cytarabine in acute myeloid leukemia
-
Lancet JE, Baer MR, Duran GE, List AF, Fielding R, Marcelletti JF, Multani PS, Sikic BI A phase I trial of continuous infusion of the multidrug resistance inhibitor zosuquidar with daunorubicin and cytarabine in acute myeloid leukemia. Leuk Res 2009; 33: 1055-1061
-
(2009)
Leuk Res
, vol.33
, pp. 1055-1061
-
-
Lancet, J.E.1
Baer, M.R.2
Duran, G.E.3
List, A.F.4
Fielding, R.5
Marcelletti, J.F.6
Multani, P.S.7
Sikic, B.I.8
-
36
-
-
21244504196
-
Phase i study of the multidrug resistance inhibitor zosuquidar administered in combination with vinorelbine in patients with advanced solid tumours
-
Le LH, Moore MJ, Siu LL, Oza AM, MacLean M, Fisher B, Chaudhary A, de Alwis DP, Slapak C, Seymour L. Phase I study of the multidrug resistance inhibitor zosuquidar administered in combination with vinorelbine in patients with advanced solid tumours. Cancer Chemother Pharmacol 2005; 56: 154-160
-
(2005)
Cancer Chemother Pharmacol
, vol.56
, pp. 154-160
-
-
Le, L.H.1
Moore, M.J.2
Siu, L.L.3
Oza, A.M.4
MacLean, M.5
Fisher, B.6
Chaudhary, A.7
De Alwis, D.P.8
Slapak, C.9
Seymour, L.10
-
37
-
-
63349111030
-
Leukemic blast and natural killer cell P-glycoprotein function and inhibition in a clinical trial of zosuquidar infusion in acute myeloid leukemia
-
Marcelletti JF, Multani PS, Lancet JE, Baer MR, Sikic BI. Leukemic blast and natural killer cell P-glycoprotein function and inhibition in a clinical trial of zosuquidar infusion in acute myeloid leukemia. Leuk Res 2009; 33: 769-774
-
(2009)
Leuk Res
, vol.33
, pp. 769-774
-
-
Marcelletti, J.F.1
Multani, P.S.2
Lancet, J.E.3
Baer, M.R.4
Sikic, B.I.5
-
38
-
-
34247213414
-
Phase I/II trial of a P-glycoprotein inhibitor, Zosuquidar.3HCl trihydrochloride (LY335979), given orally in combination with the CHOP regimen in patients with non-Hodgkin's lymphoma
-
Morschhauser F, Zinzani PL, Burgess M, Sloots L, Bouafia F, Dumontet C. Phase I/II trial of a P-glycoprotein inhibitor, Zosuquidar.3HCl trihydrochloride (LY335979), given orally in combination with the CHOP regimen in patients with non-Hodgkin's lymphoma. Leuk Lymphoma 2007; 48: 708-715
-
(2007)
Leuk Lymphoma
, vol.48
, pp. 708-715
-
-
Morschhauser, F.1
Zinzani, P.L.2
Burgess, M.3
Sloots, L.4
Bouafia, F.5
Dumontet, C.6
-
39
-
-
33745746815
-
Pharmacological strategies for overcoming multidrug resistance
-
Nobili S, Landini I, Giglioni B, Mini E. Pharmacological strategies for overcoming multidrug resistance. Curr Drug Targets 2006; 7: 861-879
-
(2006)
Curr Drug Targets
, vol.7
, pp. 861-879
-
-
Nobili, S.1
Landini, I.2
Giglioni, B.3
Mini, E.4
-
40
-
-
79951530814
-
Novel and emerging drugs for acute myeloid leukemia: Pharmacology and therapeutic activity
-
Robak T, Szmigielska-Kaplon A, Pluta A, Grzybowska-Izydorczyk O, Wolska A, Czemerska M, Wierzbowska A. Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity. Curr Med Chem 2011; 18: 638-666
-
(2011)
Curr Med Chem
, vol.18
, pp. 638-666
-
-
Robak, T.1
Szmigielska-Kaplon, A.2
Pluta, A.3
Grzybowska-Izydorczyk, O.4
Wolska, A.5
Czemerska, M.6
Wierzbowska, A.7
-
41
-
-
0036895024
-
A phase i trial of a potent P-glycoprotein inhibitor, Zosuquidar.3HCl trihydrochloride (LY335979), administered orally in combination with doxorubicin in patients with advanced malignancies
-
Rubin EH, de Alwis DP, Pouliquen I, Green L, Marder P, Lin Y, Musanti R, Grospe SL, Smith SL, Toppmeyer DL, Much J, Kane M, Chaudhary A, Jordan C, Burgess M, Slapak CA A phase I trial of a potent P-glycoprotein inhibitor, Zosuquidar.3HCl trihydrochloride (LY335979), administered orally in combination with doxorubicin in patients with advanced malignancies. Clin Cancer Res 2002; 8: 3710-3717
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3710-3717
-
-
Rubin, E.H.1
De Alwis, D.P.2
Pouliquen, I.3
Green, L.4
Marder, P.5
Lin, Y.6
Musanti, R.7
Grospe, S.L.8
Smith, S.L.9
Toppmeyer, D.L.10
Much, J.11
Kane, M.12
Chaudhary, A.13
Jordan, C.14
Burgess, M.15
Slapak, C.A.16
-
42
-
-
68149149796
-
A randomized, placebo-controlled, double-blind phase 2 study of docetaxel compared to docetaxel plus zosuquidar (LY335979) in women with metastatic or locally recurrent breast cancer who have received one prior chemotherapy regimen
-
Ruff P, Vorobiof DA, Jordaan JP, Demetriou GS, Moodley SD, Nosworthy AL, Werner ID, Raats J, Burgess LJ A randomized, placebo-controlled, double-blind phase 2 study of docetaxel compared to docetaxel plus zosuquidar (LY335979) in women with metastatic or locally recurrent breast cancer who have received one prior chemotherapy regimen. Cancer Chemother Pharmacol 2009; 64: 763-768
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, pp. 763-768
-
-
Ruff, P.1
Vorobiof, D.A.2
Jordaan, J.P.3
Demetriou, G.S.4
Moodley, S.D.5
Nosworthy, A.L.6
Werner, I.D.7
Raats, J.8
Burgess, L.J.9
-
43
-
-
2542479863
-
A Phase i trial of a potent P-glycoprotein inhibitor, zosuquidar trihydrochloride (LY335979), administered intravenously in combination with doxorubicin in patients with advanced malignancy
-
Sandler A, Gordon M, De Alwis DP, Pouliquen I, Green L, Marder P, Chaudhary A, Fife K, Battiato L, Sweeney C, Jordan C, Burgess M, Slapak CA A Phase I trial of a potent P-glycoprotein inhibitor, zosuquidar trihydrochloride (LY335979), administered intravenously in combination with doxorubicin in patients with advanced malignancy. Clin Cancer Res 2004; 10: 3265-3272
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3265-3272
-
-
Sandler, A.1
Gordon, M.2
De Alwis, D.P.3
Pouliquen, I.4
Green, L.5
Marder, P.6
Chaudhary, A.7
Fife, K.8
Battiato, L.9
Sweeney, C.10
Jordan, C.11
Burgess, M.12
Slapak, C.A.13
-
44
-
-
40349095136
-
Zosuquidar restores drug sensitivity in P-glycoprotein expressing acute myeloid leukemia (AML
-
Tang R, Faussat AM, Perrot JY, Marjanovic Z, Cohen S, Storme T, Morjani H, Legrand O, Marie JP. Zosuquidar restores drug sensitivity in P-glycoprotein expressing acute myeloid leukemia (AML). BMC Cancer 2008; 8: 51
-
(2008)
BMC Cancer
, vol.8
, pp. 51
-
-
Tang, R.1
Faussat, A.M.2
Perrot, J.Y.3
Marjanovic, Z.4
Cohen, S.5
Storme, T.6
Morjani, H.7
Legrand, O.8
Marie, J.P.9
-
45
-
-
34250163664
-
Modulation of the brain distribution of imatinib and its metabolites in mice by valspodar, zosuquidar and elacridar
-
Bihorel S, Camenisch G, Lemaire M, Scherrmann JM. Modulation of the brain distribution of imatinib and its metabolites in mice by valspodar, zosuquidar and elacridar. Pharm Res 2007; 24: 1720-1728
-
(2007)
Pharm Res
, vol.24
, pp. 1720-1728
-
-
Bihorel, S.1
Camenisch, G.2
Lemaire, M.3
Scherrmann, J.M.4
-
46
-
-
33845300239
-
Role of drug efflux carriers in the healthy and diseased brain
-
Hermann DM, Kilic E, Spudich A, Kramer SD, Wunderli-Allenspach H, Bassetti CL. Role of drug efflux carriers in the healthy and diseased brain. Ann Neurol 2006; 60: 489-498
-
(2006)
Ann Neurol
, vol.60
, pp. 489-498
-
-
Hermann, D.M.1
Kilic, E.2
Spudich, A.3
Kramer, S.D.4
Wunderli-Allenspach, H.5
Bassetti, C.L.6
-
47
-
-
0442313667
-
The influence of the P-glycoprotein inhibitor zosuquidar trihydrochloride (LY335979) on the brain penetration of paclitaxel in mice
-
Kemper EM, Cleypool C, Boogerd W, Beijnen JH, van Tellingen O. The influence of the P-glycoprotein inhibitor zosuquidar trihydrochloride (LY335979) on the brain penetration of paclitaxel in mice. Cancer Chemother Pharmacol 2004; 53: 173-178
-
(2004)
Cancer Chemother Pharmacol
, vol.53
, pp. 173-178
-
-
Kemper, E.M.1
Cleypool, C.2
Boogerd, W.3
Beijnen, J.H.4
Van Tellingen, O.5
-
48
-
-
84873050654
-
Analysis of the inhibition potential of zosuquidar derivatives on selected bacterial and fungal ABC transporters
-
Infed N, Smits SH, Dittrich T, Braun M, Driessen AJ, Hanekop N, Schmitt L. Analysis of the inhibition potential of zosuquidar derivatives on selected bacterial and fungal ABC transporters. Mol Membr Biol 2013; 30: 217-227
-
(2013)
Mol Membr Biol
, vol.30
, pp. 217-227
-
-
Infed, N.1
Smits, S.H.2
Dittrich, T.3
Braun, M.4
Driessen, A.J.5
Hanekop, N.6
Schmitt, L.7
-
49
-
-
0032980591
-
Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents
-
Lehne G, De Angelis P, den Boer M, Rugstad HE. Growth inhibition, cytokinesis failure and apoptosis of multidrug-resistant leukemia cells after treatment with P-glycoprotein inhibitory agents. Leukemia 1999; 13: 768-778
-
(1999)
Leukemia
, vol.13
, pp. 768-778
-
-
Lehne, G.1
De Angelis, P.2
Den Boer, M.3
Rugstad, H.E.4
-
50
-
-
67650733509
-
P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients
-
Tang R, Cohen S, Perrot JY, Faussat AM, Zuany-Amorim C, Marjanovic Z, Morjani H, Fava F, Corre E, Legrand O, Marie JP. P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients. BMC Cancer 2009; 9: 199
-
(2009)
BMC Cancer
, vol.9
, pp. 199
-
-
Tang, R.1
Cohen, S.2
Perrot, J.Y.3
Faussat, A.M.4
Zuany-Amorim, C.5
Marjanovic, Z.6
Morjani, H.7
Fava, F.8
Corre, E.9
Legrand, O.10
Marie, J.P.11
-
51
-
-
0242426629
-
Role of Ca2+-Activated K+ channels in human erythrocyte apoptosis
-
Lang PA, Kaiser S, Myssina S, Wieder T, Lang F, Huber SM. Role of Ca2+-Activated K+ channels in human erythrocyte apoptosis. Am J Physiol Cell Physiol 2003; 285: C1553-C1560
-
(2003)
Am J Physiol Cell Physiol
, vol.285
, pp. C1553-C1560
-
-
Lang, P.A.1
Kaiser, S.2
Myssina, S.3
Wieder, T.4
Lang, F.5
Huber, S.M.6
-
53
-
-
84868321858
-
Sphingomyelinaseinduced adhesion of eryptotic erythrocytes to endothelial cells
-
Abed M, Towhid ST, Mia S, Pakladok T, Alesutan I, Borst O, Gawaz M, Gulbins E, Lang F. Sphingomyelinaseinduced adhesion of eryptotic erythrocytes to endothelial cells. Am J Physiol Cell Physiol 2012; 303: C991-999
-
(2012)
Am J Physiol Cell Physiol
, vol.303
, pp. C991-999
-
-
Abed, M.1
Towhid, S.T.2
Mia, S.3
Pakladok, T.4
Alesutan, I.5
Borst, O.6
Gawaz, M.7
Gulbins, E.8
Lang, F.9
-
54
-
-
84869013866
-
In vitro effect of CTAB-And PEG-coated gold nanorods on the induction of eryptosis/erythroptosis in human erythrocytes
-
Lau IP, Chen H, Wang J, Ong HC, Leung KC, Ho HP, Kong SK. In vitro effect of CTAB-And PEG-coated gold nanorods on the induction of eryptosis/erythroptosis in human erythrocytes. Nanotoxicology 2012; 6: 847-856
-
(2012)
Nanotoxicology
, vol.6
, pp. 847-856
-
-
Lau, I.P.1
Chen, H.2
Wang, J.3
Ong, H.C.4
Leung, K.C.5
Ho, H.P.6
Kong, S.K.7
-
55
-
-
84884907779
-
Erythrocyte caspase-3 activation and oxidative imbalance in erythrocytes and in plasma of type 2 diabetic patients
-
Maellaro E, Leoncini S, Moretti D, Del Bello B, Tanganelli I, De Felice C, Ciccoli L. Erythrocyte caspase-3 activation and oxidative imbalance in erythrocytes and in plasma of type 2 diabetic patients. Acta Diabetol 2013; 50: 489-495
-
(2013)
Acta Diabetol
, vol.50
, pp. 489-495
-
-
Maellaro, E.1
Leoncini, S.2
Moretti, D.3
Del Bello, B.4
Tanganelli, I.5
De Felice, C.6
Ciccoli, L.7
-
56
-
-
84858211907
-
Plasmodium falciparum-infected erythrocytes induce granzyme B by NK cells through expression of host-Hsp70
-
Bottger E, Multhoff G, Kun JF, Esen M. Plasmodium falciparum-infected erythrocytes induce granzyme B by NK cells through expression of host-Hsp70. PLoS One 2012; 7: e33774
-
(2012)
PLoS One
, vol.7
, pp. e33774
-
-
Bottger, E.1
Multhoff, G.2
Kun, J.F.3
Esen, M.4
-
57
-
-
84861017791
-
Increased caspase-3 immunoreactivity of erythrocytes n STZ diabetic rats
-
Firat U, Kaya S, Cim A, Buyukbayram H, Gokalp O, Dal MS, Tamer MN. Increased caspase-3 immunoreactivity of erythrocytes n STZ diabetic rats. Exp Diabetes Res 2012; 2012: 316384
-
(2012)
Exp Diabetes Res
, vol.2012
, pp. 316384
-
-
Firat, U.1
Kaya, S.2
Cim, A.3
Buyukbayram, H.4
Gokalp, O.5
Dal, M.S.6
Tamer, M.N.7
-
58
-
-
84857798694
-
Understanding the mechanisms for metabolism-linked hemolytic toxicity of primaquine against glucose 6-phosphate dehydrogenase deficient human erythrocytes: Evaluation of eryptotic pathway
-
Ganesan S, Chaurasiya ND, Sahu R, Walker LA, Tekwani BL. Understanding the mechanisms for metabolism-linked hemolytic toxicity of primaquine against glucose 6-phosphate dehydrogenase deficient human erythrocytes: evaluation of eryptotic pathway. Toxicology 2012; 294: 54-60
-
(2012)
Toxicology
, vol.294
, pp. 54-60
-
-
Ganesan, S.1
Chaurasiya, N.D.2
Sahu, R.3
Walker, L.A.4
Tekwani, B.L.5
-
59
-
-
84862871418
-
Polyphyllin D induces apoptosis in human erythrocytes through Ca(2)(+) rise and membrane permeabilization
-
Gao M, Cheung KL, Lau IP, Yu WS, Fung KP, Yu B, Loo JF, Kong SK. Polyphyllin D induces apoptosis in human erythrocytes through Ca(2)(+) rise and membrane permeabilization. Arch Toxicol 2012; 86: 741-752
-
(2012)
Arch Toxicol
, Issue.86
, pp. 741-752
-
-
Gao, M.1
Cheung, K.L.2
Lau, I.P.3
Yu, W.S.4
Fung, K.P.5
Yu, B.6
Loo, J.F.7
Kong, S.K.8
-
60
-
-
84860837097
-
The impact of erythrocyte age on eryptosis
-
Ghashghaeinia M, Cluitmans JC, Akel A, Dreischer P, Toulany M, Koberle M, Skabytska Y, Saki M, Biedermann T, Duszenko M, Lang F, Wieder T, Bosman GJ. The impact of erythrocyte age on eryptosis. Br J Haematol 2012; 157: 606-614
-
(2012)
Br J Haematol
, vol.157
, pp. 606-614
-
-
Ghashghaeinia, M.1
Cluitmans, J.C.2
Akel, A.3
Dreischer, P.4
Toulany, M.5
Koberle, M.6
Skabytska, Y.7
Saki, M.8
Biedermann, T.9
Duszenko, M.10
Lang, F.11
Wieder, T.12
Bosman, G.J.13
-
61
-
-
84893057981
-
Geldanamycin-induced phosphatidylserine translocation in the erythrocyte membrane
-
Jilani K, Qadri SM, Lang F. Geldanamycin-induced phosphatidylserine translocation in the erythrocyte membrane. Cell Physiol Biochem 2013; 32: 1600-1609
-
(2013)
Cell Physiol Biochem
, vol.32
, pp. 1600-1609
-
-
Jilani, K.1
Qadri, S.M.2
Lang, F.3
-
62
-
-
84874680927
-
Ca influx versus efflux during eryptosis in uremic erythrocytes
-
Polak-Jonkisz D, Purzyc L. Ca Influx versus Efflux during Eryptosis in Uremic Erythrocytes. Blood Purif 2012; 34: 209-210
-
(2012)
Blood Purif
, vol.34
, pp. 209-210
-
-
Polak-Jonkisz, D.1
Purzyc, L.2
-
63
-
-
84860322995
-
Salidroside protects human erythrocytes against hydrogen peroxide-induced apoptosis
-
Qian EW, Ge DT, Kong SK. Salidroside protects human erythrocytes against hydrogen peroxide-induced apoptosis. J Nat Prod 2012; 75: 531-537
-
(2012)
J Nat Prod
, vol.75
, pp. 531-537
-
-
Qian, E.W.1
Ge, D.T.2
Kong, S.K.3
-
64
-
-
84874232618
-
Differential erythropoietin action upon cells induced to eryptosis by different agents
-
Vota DM, Maltaneri RE, Wenker SD, Nesse AB, Vittori DC. Differential erythropoietin action upon cells induced to eryptosis by different agents. Cell Biochem Biophys 2013; 65: 145-157
-
(2013)
Cell Biochem Biophys
, vol.65
, pp. 145-157
-
-
Vota, D.M.1
Maltaneri, R.E.2
Wenker, S.D.3
Nesse, A.B.4
Vittori, D.C.5
-
65
-
-
84856108016
-
Deoxygenation-induced and Ca(2+) dependent phosphatidylserine externalisation in red blood cells from normal individuals and sickle cell patients
-
Weiss E, Cytlak UM, Rees DC, Osei A, Gibson JS. Deoxygenation-induced and Ca(2+) dependent phosphatidylserine externalisation in red blood cells from normal individuals and sickle cell patients. Cell Calcium 2012; 51: 51-56
-
(2012)
Cell Calcium
, Issue.51
, pp. 51-56
-
-
Weiss, E.1
Cytlak, U.M.2
Rees, D.C.3
Osei, A.4
Gibson, J.S.5
-
66
-
-
45149094904
-
Environmental stress, erythrocyte dysfunctions, inflammation, and the metabolic syndrome adaptations to CO2 increases?
-
Zappulla D. Environmental stress, erythrocyte dysfunctions, inflammation, and the metabolic syndrome: adaptations to CO2 increases?. J Cardiometab Syndr 2008; 3: 30-34
-
(2008)
J Cardiometab Syndr
, vol.3
, pp. 30-34
-
-
Zappulla, D.1
-
68
-
-
84878060480
-
The uremic toxin acrolein promotes suicidal erythrocyte death
-
Ahmed MS, Langer H, Abed M, Voelkl J, Lang F. The uremic toxin acrolein promotes suicidal erythrocyte death. Kidney Blood Press Res 2013; 37: 158-167
-
(2013)
Kidney Blood Press Res
, vol.37
, pp. 158-167
-
-
Ahmed, M.S.1
Langer, H.2
Abed, M.3
Voelkl, J.4
Lang, F.5
-
69
-
-
84888182490
-
Age sensitivity of nfkappab abundance and programmed cell death in erythrocytes induced by nfkappab inhibitors
-
Ghashghaeinia M, Cluitmans JC, Toulany M, Saki M, Koberle M, Lang E, Dreischer P, Biedermann T, Duszenko M, Lang F, Bosman GJ, Wieder T. Age Sensitivity of NFkappaB Abundance and Programmed Cell Death in Erythrocytes Induced by NFkappaB Inhibitors. Cell Physiol Biochem 2013; 32: 801-813
-
(2013)
Cell Physiol Biochem
, vol.32
, pp. 801-813
-
-
Ghashghaeinia, M.1
Cluitmans, J.C.2
Toulany, M.3
Saki, M.4
Koberle, M.5
Lang, E.6
Dreischer, P.7
Biedermann, T.8
Duszenko, M.9
Lang, F.10
Bosman, G.J.11
Wieder, T.12
-
70
-
-
84891361707
-
Triggering of suicidal erythrocyte death by penta-o-galloyl-beta-dglucose
-
Alzoubi K, Honisch S, Abed M, Lang F. Triggering of Suicidal Erythrocyte Death by Penta-O-galloyl-beta-dglucose. Toxins (Basel) 2014; 6: 54-65
-
(2014)
Toxins (Basel)
, vol.6
, pp. 54-65
-
-
Alzoubi, K.1
Honisch, S.2
Abed, M.3
Lang, F.4
-
71
-
-
84880481609
-
Fluoxetine induced suicidal erythrocyte death
-
Jilani K, Enkel S, Bissinger R, Almilaji A, Abed M, Lang F. Fluoxetine induced suicidal erythrocyte death. Toxins (Basel) 2013; 5: 1230-1243
-
(2013)
Toxins (Basel)
, vol.5
, pp. 1230-1243
-
-
Jilani, K.1
Enkel, S.2
Bissinger, R.3
Almilaji, A.4
Abed, M.5
Lang, F.6
-
75
-
-
84897963132
-
Effect of nitazoxanide on erythrocytes
-
Arnold M, Lang E, Modicano P, Bissinger R, Faggio C, Abed M, Lang F. Effect of nitazoxanide on erythrocytes. Basic Clin Pharmacol Toxicol 2014; 114: 421-426
-
(2014)
Basic Clin Pharmacol Toxicol
, vol.114
, pp. 421-426
-
-
Arnold, M.1
Lang, E.2
Modicano, P.3
Bissinger, R.4
Faggio, C.5
Abed, M.6
Lang, F.7
-
77
-
-
84901353440
-
Stimulation of erythrocyte cell membrane scrambling by mitotane
-
Jacobi J, Lang E, Bissinger R, Frauenfeld L, Modicano P, Faggio C, Abed M, Lang F. Stimulation of erythrocyte cell membrane scrambling by mitotane. Cell Physiol Biochem 2014; 33: 1516-1526
-
(2014)
Cell Physiol Biochem
, vol.33
, pp. 1516-1526
-
-
Jacobi, J.1
Lang, E.2
Bissinger, R.3
Frauenfeld, L.4
Modicano, P.5
Faggio, C.6
Abed, M.7
Lang, F.8
-
78
-
-
84902900622
-
Stimulation of erythrocyte cell membrane scrambling by gedunin
-
Lupescu A, Bissinger R, Warsi J, Jilani K, Lang F. Stimulation of erythrocyte cell membrane scrambling by gedunin. Cell Physiol Biochem 2014; 33: 1838-1848
-
(2014)
Cell Physiol Biochem
, vol.33
, pp. 1838-1848
-
-
Lupescu, A.1
Bissinger, R.2
Warsi, J.3
Jilani, K.4
Lang, F.5
-
79
-
-
84891069635
-
Sensitization of erythrocytes to suicidal erythrocyte death following water deprivation
-
Abed M, Feger M, Alzoubi K, Pakladok T, Frauenfeld L, Geiger C, Towhid ST, Lang F. Sensitization of erythrocytes to suicidal erythrocyte death following water deprivation. Kidney Blood Press Res 2013; 37: 567-578
-
(2013)
Kidney Blood Press Res
, vol.37
, pp. 567-578
-
-
Abed, M.1
Feger, M.2
Alzoubi, K.3
Pakladok, T.4
Frauenfeld, L.5
Geiger, C.6
Towhid, S.T.7
Lang, F.8
-
80
-
-
84920871464
-
Stimulation of suicidal erythrocyte death by artesunate
-
Alzoubi K, Calabro S, Bissinger R, Abed M, Faggio C, Lang F. Stimulation of suicidal erythrocyte death by artesunate. Cell Physiol Biochem 2014; 34: 2232-2244
-
(2014)
Cell Physiol Biochem
, vol.34
, pp. 2232-2244
-
-
Alzoubi, K.1
Calabro, S.2
Bissinger, R.3
Abed, M.4
Faggio, C.5
Lang, F.6
-
81
-
-
84912135458
-
Mitoxantrone-induced suicidal erythrocyte death
-
Arnold M, Bissinger R, Lang F. Mitoxantrone-induced suicidal erythrocyte death. Cell Physiol Biochem 2014; 34: 1756-1767
-
(2014)
Cell Physiol Biochem
, vol.34
, pp. 1756-1767
-
-
Arnold, M.1
Bissinger, R.2
Lang, F.3
-
83
-
-
84906022445
-
Stimulation of eryptosis by cryptotanshinone
-
Bissinger R, Lupescu A, Zelenak C, Jilani K, Lang F. Stimulation of eryptosis by cryptotanshinone. Cell Physiol Biochem 2014; 34: 432-442
-
(2014)
Cell Physiol Biochem
, vol.34
, pp. 432-442
-
-
Bissinger, R.1
Lupescu, A.2
Zelenak, C.3
Jilani, K.4
Lang, F.5
-
84
-
-
84890680851
-
Estramustine-induced suicidal erythrocyte death
-
Bissinger R, Modicano P, Frauenfeld L, Lang E, Jacobi J, Faggio C, Lang F. Estramustine-induced suicidal erythrocyte death. Cell Physiol Biochem 2013; 32: 1426-1436
-
(2013)
Cell Physiol Biochem
, vol.32
, pp. 1426-1436
-
-
Bissinger, R.1
Modicano, P.2
Frauenfeld, L.3
Lang, E.4
Jacobi, J.5
Faggio, C.6
Lang, F.7
-
85
-
-
84911500539
-
Aristolochic acid induced suicidal erythrocyte death
-
Malik A, Bissinger R, Calabro S, Faggio C, Jilani K, Lang F. Aristolochic acid induced suicidal erythrocyte death. Kidney Blood Press Res 2014; 39: 408-419
-
(2014)
Kidney Blood Press Res
, vol.39
, pp. 408-419
-
-
Malik, A.1
Bissinger, R.2
Calabro, S.3
Faggio, C.4
Jilani, K.5
Lang, F.6
-
86
-
-
84908609487
-
Oxysterol mixture in hypercholesterolemiarelevant proportion causes oxidative stress-dependent eryptosis
-
Tesoriere L, Attanzio A, Allegra M, Cilla A, Gentile C, Livrea MA. Oxysterol mixture in hypercholesterolemiarelevant proportion causes oxidative stress-dependent eryptosis. Cell Physiol Biochem 2014; 34: 1075-1089
-
(2014)
Cell Physiol Biochem
, vol.34
, pp. 1075-1089
-
-
Tesoriere, L.1
Attanzio, A.2
Allegra, M.3
Cilla, A.4
Gentile, C.5
Livrea, M.A.6
-
87
-
-
84895665358
-
Stimulation of suicidal erythrocyte death by increased extracellular phosphate concentrations
-
Voelkl J, Alzoubi K, Mamar AK, Ahmed MS, Abed M, Lang F. Stimulation of suicidal erythrocyte death by increased extracellular phosphate concentrations. Kidney Blood Press Res 2013; 38: 42-51
-
(2013)
Kidney Blood Press Res
, vol.38
, pp. 42-51
-
-
Voelkl, J.1
Alzoubi, K.2
Mamar, A.K.3
Ahmed, M.S.4
Abed, M.5
Lang, F.6
-
88
-
-
84912091297
-
Involvement of calcium, reactive oxygen species, and ATP in hexavalent chromium-induced damage in red blood cells
-
Zhang R, Xiang Y, Ran Q, Deng X, Xiao Y, Xiang L, Li Z. Involvement of calcium, reactive oxygen species, and ATP in hexavalent chromium-induced damage in red blood cells. Cell Physiol Biochem 2014; 34: 1780-1791
-
(2014)
Cell Physiol Biochem
, vol.34
, pp. 1780-1791
-
-
Zhang, R.1
Xiang, Y.2
Ran, Q.3
Deng, X.4
Xiao, Y.5
Xiang, L.6
Li, Z.7
-
89
-
-
84895932369
-
Induction of suicidal erythrocyte death by novobiocin
-
Lupescu A, Bissinger R, Herrmann T, Oswald G, Jilani K, Lang F. Induction of suicidal erythrocyte death by novobiocin. Cell Physiol Biochem 2014; 33: 670-680
-
(2014)
Cell Physiol Biochem
, vol.33
, pp. 670-680
-
-
Lupescu, A.1
Bissinger, R.2
Herrmann, T.3
Oswald, G.4
Jilani, K.5
Lang, F.6
-
91
-
-
84920883504
-
DMT1-mutant erythrocytes have shortened life span, accelerated glycolysis and increased oxidative stress
-
Zidova Z, Kapralova K, Koralkova P, Mojzikova R, Dolezal D, Divoky V, Horvathova M. DMT1-mutant erythrocytes have shortened life span, accelerated glycolysis and increased oxidative stress. Cell Physiol Biochem 2014; 34: 2221-2231
-
(2014)
Cell Physiol Biochem
, vol.34
, pp. 2221-2231
-
-
Zidova, Z.1
Kapralova, K.2
Koralkova, P.3
Mojzikova, R.4
Dolezal, D.5
Divoky, V.6
Horvathova, M.7
-
92
-
-
0242495628
-
Bioanalysis of zosuquidar trihydrochloride (LY335979) in small volumes of human and murine plasma by ion-pairing reversed-phase highperformance liquid chromatography
-
Kemper EM, Ouwehand M, Beijnen JH, van Tellingen O. Bioanalysis of zosuquidar trihydrochloride (LY335979) in small volumes of human and murine plasma by ion-pairing reversed-phase highperformance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci 2003; 798: 63-68
-
(2003)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.798
, pp. 63-68
-
-
Kemper, E.M.1
Ouwehand, M.2
Beijnen, J.H.3
Van Tellingen, O.4
-
93
-
-
3042766320
-
Population pharmacokinetic model for daunorubicin and daunorubicinol coadministered with zosuquidar.3HCl (LY335979
-
Callies S, de Alwis DP, Mehta A, Burgess M, Aarons L. Population pharmacokinetic model for daunorubicin and daunorubicinol coadministered with zosuquidar.3HCl (LY335979). Cancer Chemother Pharmacol 2004; 54: 39-48
-
(2004)
Cancer Chemother Pharmacol
, vol.54
, pp. 39-48
-
-
Callies, S.1
De Alwis, D.P.2
Mehta, A.3
Burgess, M.4
Aarons, L.5
-
94
-
-
84860348582
-
Enhanced suicidal erythrocyte death in mice carrying a loss-of-function mutation of the adenomatous polyposis coli gene
-
Qadri SM, Mahmud H, Lang E, Gu S, Bobbala D, Zelenak C, Jilani K, Siegfried A, Foller M, Lang F. Enhanced suicidal erythrocyte death in mice carrying a loss-of-function mutation of the adenomatous polyposis coli gene. J Cell Mol Med 2012; 16: 1085-1093
-
(2012)
J Cell Mol Med
, vol.16
, pp. 1085-1093
-
-
Qadri, S.M.1
Mahmud, H.2
Lang, E.3
Gu, S.4
Bobbala, D.5
Zelenak, C.6
Jilani, K.7
Siegfried, A.8
Foller, M.9
Lang, F.10
-
95
-
-
84920990448
-
Conjugated bilirubin triggers anemia by inducing erythrocyte death
-
Lang E, Gatidis S, Freise NF, Bock H, Kubitz R, Lauermann C, Orth HM, Klindt C, Schuier M, Keitel V, Reich M, Liu G, Schmidt S, Xu HC, Qadri SM, Herebian D, Pandyra AA, Mayatepek E, Gulbins E, Lang F, Haussinger D, Lang KS, Foller M, Lang PA. Conjugated bilirubin triggers anemia by inducing erythrocyte death. Hepatology 2015; 61: 275-284
-
(2015)
Hepatology
, vol.61
, pp. 275-284
-
-
Lang, E.1
Gatidis, S.2
Freise, N.F.3
Bock, H.4
Kubitz, R.5
Lauermann, C.6
Orth, H.M.7
Klindt, C.8
Schuier, M.9
Keitel, V.10
Reich, M.11
Liu, G.12
Schmidt, S.13
Xu, H.C.14
Qadri, S.M.15
Herebian, D.16
Pandyra, A.A.17
Mayatepek, E.18
Gulbins, E.19
Lang, F.20
Haussinger, D.21
Lang, K.S.22
Foller, M.23
Lang, P.A.24
more..
-
96
-
-
84857435212
-
Eryptosis and oxidative damage in type 2 diabetic mellitus patients with chronic kidney disease
-
Calderon-Salinas JV, Munoz-Reyes EG, Guerrero-Romero JF, Rodriguez-Moran M, Bracho-Riquelme RL, Carrera-Gracia MA, Quintanar-Escorza MA. Eryptosis and oxidative damage in type 2 diabetic mellitus patients with chronic kidney disease. Mol Cell Biochem 2011; 357: 171-179
-
(2011)
Mol Cell Biochem
, vol.357
, pp. 171-179
-
-
Calderon-Salinas, J.V.1
Munoz-Reyes, E.G.2
Guerrero-Romero, J.F.3
Rodriguez-Moran, M.4
Bracho-Riquelme, R.L.5
Carrera-Gracia, M.A.6
Quintanar-Escorza, M.A.7
-
97
-
-
33845602187
-
Stimulation of suicidal erythrocyte death by methylglyoxal
-
Nicolay J P, Schneider J, Niemoeller OM, Artunc F, Portero-Otin M, Haik G, Jr., Thornalley PJ, Schleicher E, Wieder T, Lang F. Stimulation of suicidal erythrocyte death by methylglyoxal. Cell Physiol Biochem 2006; 18: 223-232
-
(2006)
Cell Physiol Biochem
, vol.18
, pp. 223-232
-
-
Nicolay, J.P.1
Schneider, J.2
Niemoeller, O.M.3
Artunc, F.4
Portero-Otin, M.5
Haik, G.6
Thornalley, P.J.7
Schleicher, E.8
Wieder, T.9
Lang, F.10
-
98
-
-
84906791224
-
Suicidal erythrocyte death in endstage renal disease
-
Abed M, Artunc F, Alzoubi K, Honisch S, Baumann D, Foller M, Lang F. Suicidal erythrocyte death in endstage renal disease. J Mol Med (Berl) 2014; 92: 871-879
-
(2014)
J Mol Med (Berl)
, vol.92
, pp. 871-879
-
-
Abed, M.1
Artunc, F.2
Alzoubi, K.3
Honisch, S.4
Baumann, D.5
Foller, M.6
Lang, F.7
-
99
-
-
33646337960
-
Suicidal death of erythrocytes in recurrent hemolytic uremic syndrome
-
Lang PA, Beringer O, Nicolay JP, Amon O, Kempe DS, Hermle T, Attanasio P, Akel A, Schafer R, Friedrich B, Risler T, Baur M, Olbricht CJ, Zimmerhackl LB, Zipfel PF, Wieder T, Lang F. Suicidal death of erythrocytes in recurrent hemolytic uremic syndrome. J Mol Med (Berl) 2006; 84: 378-388
-
(2006)
J Mol Med (Berl)
, vol.84
, pp. 378-388
-
-
Lang, P.A.1
Beringer, O.2
Nicolay, J.P.3
Amon, O.4
Kempe, D.S.5
Hermle, T.6
Attanasio, P.7
Akel, A.8
Schafer, R.9
Friedrich, B.10
Risler, T.11
Baur, M.12
Olbricht, C.J.13
Zimmerhackl, L.B.14
Zipfel, P.F.15
Wieder, T.16
Lang, F.17
-
100
-
-
33847129228
-
Suicidal erythrocyte death in sepsis
-
Kempe DS, Akel A, Lang PA, Hermle T, Biswas R, Muresanu J, Friedrich B, Dreischer P, Wolz C, Schumacher U, Peschel A, Gotz F, Doring G, Wieder T, Gulbins E, Lang F. Suicidal erythrocyte death in sepsis. J Mol Med (Berl) 2007; 85: 273-281
-
(2007)
J Mol Med (Berl)
, vol.85
, pp. 273-281
-
-
Kempe, D.S.1
Akel, A.2
Lang, P.A.3
Hermle, T.4
Biswas, R.5
Muresanu, J.6
Friedrich, B.7
Dreischer, P.8
Wolz, C.9
Schumacher, U.10
Peschel, A.11
Gotz, F.12
Doring, G.13
Wieder, T.14
Gulbins, E.15
Lang, F.16
-
101
-
-
77952617668
-
Temperature sensitivity of suicidal erythrocyte death
-
Foller M, Braun M, Qadri SM, Lang E, Mahmud H, Lang F. Temperature sensitivity of suicidal erythrocyte death. Eur J Clin Invest 2010; 40: 534-540
-
(2010)
Eur J Clin Invest
, vol.40
, pp. 534-540
-
-
Foller, M.1
Braun, M.2
Qadri, S.M.3
Lang, E.4
Mahmud, H.5
Lang, F.6
-
102
-
-
79959462340
-
Hemotrophic mycoplasmas induce programmed cell death in red blood cells
-
Felder KM, Hoelzle K, Ritzmann M, Kilchling T, Schiele D, Heinritzi K, Groebel K, Hoelzle LE. Hemotrophic mycoplasmas induce programmed cell death in red blood cells. Cell Physiol Biochem 2011; 27: 557-564
-
(2011)
Cell Physiol Biochem
, vol.27
, pp. 557-564
-
-
Felder, K.M.1
Hoelzle, K.2
Ritzmann, M.3
Kilchling, T.4
Schiele, D.5
Heinritzi, K.6
Groebel, K.7
Hoelzle, L.E.8
-
103
-
-
70450257793
-
Accelerated clearance of Plasmodium-infected erythrocytes in sickle cell trait and annexin-A7 deficiency
-
Lang PA, Kasinathan RS, Brand VB, Duranton C, Lang C, Koka S, Shumilina E, Kempe DS, Tanneur V, Akel A, Lang KS, Foller M, Kun JF, Kremsner PG, Wesselborg S, Laufer S, Clemen CS, Herr C, Noegel AA, Wieder T, Gulbins E, Lang F, Huber SM. Accelerated clearance of Plasmodium-infected erythrocytes in sickle cell trait and annexin-A7 deficiency. Cell Physiol Biochem 2009; 24: 415-428
-
(2009)
Cell Physiol Biochem
, vol.24
, pp. 415-428
-
-
Lang, P.A.1
Kasinathan, R.S.2
Brand, V.B.3
Duranton, C.4
Lang, C.5
Koka, S.6
Shumilina, E.7
Kempe, D.S.8
Tanneur, V.9
Akel, A.10
Lang, K.S.11
Foller, M.12
Kun, J.F.13
Kremsner, P.G.14
Wesselborg, S.15
Laufer, S.16
Clemen, C.S.17
Herr, C.18
Noegel, A.A.19
Wieder, T.20
Gulbins, E.21
Lang, F.22
Huber, S.M.23
more..
-
104
-
-
33644891025
-
Enhanced programmed cell death of iron-deficient erythrocytes
-
Kempe DS, Lang PA, Duranton C, Akel A, Lang KS, Huber SM, Wieder T, Lang F. Enhanced programmed cell death of iron-deficient erythrocytes. FASEB J 2006; 20: 368-370
-
(2006)
FASEB J
, vol.20
, pp. 368-370
-
-
Kempe, D.S.1
Lang, P.A.2
Duranton, C.3
Akel, A.4
Lang, K.S.5
Huber, S.M.6
Wieder, T.7
Lang, F.8
-
105
-
-
0036432879
-
Enhanced erythrocyte apoptosis in sickle cell anemia, thalassemia and glucose-6-phosphate dehydrogenase deficiency
-
Lang KS, Roll B, Myssina S, Schittenhelm M, Scheel-Walter HG, Kanz L, Fritz J, Lang F, Huber SM, Wieder T. Enhanced erythrocyte apoptosis in sickle cell anemia, thalassemia and glucose-6-phosphate dehydrogenase deficiency. Cell Physiol Biochem 2002; 12: 365-372
-
(2002)
Cell Physiol Biochem
, vol.12
, pp. 365-372
-
-
Lang, K.S.1
Roll, B.2
Myssina, S.3
Schittenhelm, M.4
Scheel-Walter, H.G.5
Kanz, L.6
Fritz, J.7
Lang, F.8
Huber, S.M.9
Wieder, T.10
-
106
-
-
33846985938
-
Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide
-
Lang PA, Schenck M, Nicolay JP, Becker JU, Kempe DS, Lupescu A, Koka S, Eisele K, Klarl BA, Rubben H, Schmid KW, Mann K, Hildenbrand S, Hefter H, Huber SM, Wieder T, Erhardt A, Haussinger D, Gulbins E, Lang F. Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide. Nat Med 2007; 13: 164-170
-
(2007)
Nat Med
, vol.13
, pp. 164-170
-
-
Lang, P.A.1
Schenck, M.2
Nicolay, J.P.3
Becker, J.U.4
Kempe, D.S.5
Lupescu, A.6
Koka, S.7
Eisele, K.8
Klarl, B.A.9
Rubben, H.10
Schmid, K.W.11
Mann, K.12
Hildenbrand, S.13
Hefter, H.14
Huber, S.M.15
Wieder, T.16
Erhardt, A.17
Haussinger, D.18
Gulbins, E.19
Lang, F.20
more..
-
107
-
-
84856573258
-
Dynamic adhesion of eryptotic erythrocytes to endothelial cells via CXCL16/SR-PSOX
-
Borst O, Abed M, Alesutan I, Towhid ST, Qadri SM, Foller M, Gawaz M, Lang F. Dynamic adhesion of eryptotic erythrocytes to endothelial cells via CXCL16/SR-PSOX. Am J Physiol Cell Physiol 2012; 302: C644-C651
-
(2012)
Am J Physiol Cell Physiol
, vol.302
, pp. C644-C651
-
-
Borst, O.1
Abed, M.2
Alesutan, I.3
Towhid, S.T.4
Qadri, S.M.5
Foller, M.6
Gawaz, M.7
Lang, F.8
-
108
-
-
0032811978
-
Role of red blood cells in thrombosis
-
Andrews DA, Low PS. Role of red blood cells in thrombosis. Curr Opin Hematol 1999; 6: 76-82
-
(1999)
Curr Opin Hematol
, vol.6
, pp. 76-82
-
-
Andrews, D.A.1
Low, P.S.2
-
109
-
-
33846444733
-
Lysophosphatidic acid induces thrombogenic activity through phosphatidylserine exposure and procoagulant microvesicle generation i human erythrocytes
-
Chung SM, Bae ON, Lim KM, Noh JY, Lee MY, Jung YS, Chung JH. Lysophosphatidic acid induces thrombogenic activity through phosphatidylserine exposure and procoagulant microvesicle generation i human erythrocytes. Arterioscler Thromb Vasc Biol 2007; 27: 414-421
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 414-421
-
-
Chung, S.M.1
Bae, O.N.2
Lim, K.M.3
Noh, J.Y.4
Lee, M.Y.5
Jung, Y.S.6
Chung, J.H.7
-
110
-
-
18544381354
-
Surface exposure of phosphatidylserine in pathological cells
-
Zwaal RF, Comfurius P, Bevers EM. Surface exposure of phosphatidylserine in pathological cells. Cell Mol Life Sci 2005; 62: 971-988
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 971-988
-
-
Zwaal, R.F.1
Comfurius, P.2
Bevers, E.M.3
-
111
-
-
0032748399
-
Phosphatidylserine-related adhesion of human erythrocytes to vascular endothelium
-
Closse C, Dachary-Prigent J, Boisseau MR. Phosphatidylserine-related adhesion of human erythrocytes to vascular endothelium. Br J Haematol 1999; 107: 300-302
-
(1999)
Br J Haematol
, vol.107
, pp. 300-302
-
-
Closse, C.1
Dachary-Prigent, J.2
Boisseau, M.R.3
-
112
-
-
0038481238
-
Altered erythrocyte endothelial adherence and membrane phospholipid asymmetry in hereditary hydrocytosis
-
Gallagher PG, Chang SH, Rettig M P, Neely JE, Hillery CA, Smith BD, Low PS. Altered erythrocyte endothelial adherence and membrane phospholipid asymmetry in hereditary hydrocytosis. Blood 2003; 101: 4625-4627
-
(2003)
Blood
, vol.101
, pp. 4625-4627
-
-
Gallagher, P.G.1
Chang, S.H.2
Rettig, M.P.3
Neely, J.E.4
Hillery, C.A.5
Smith, B.D.6
Low, P.S.7
-
113
-
-
35848958833
-
Mechanisms of uremic erythrocyte-induced adhesion of human monocytes to cultured endothelial cells
-
Pandolfi A, Di Pietro N, Sirolli V, Giardinelli A, Di Silvestre S, Amoroso L, Di Tomo P, Capani F, Consoli A, Bonomini M. Mechanisms of uremic erythrocyte-induced adhesion of human monocytes to cultured endothelial cells. J Cell Physiol 2007; 213: 699-709
-
(2007)
J Cell Physiol
, vol.213
, pp. 699-709
-
-
Pandolfi, A.1
Di Pietro, N.2
Sirolli, V.3
Giardinelli, A.4
Di Silvestre, S.5
Amoroso, L.6
Di Tomo, P.7
Capani, F.8
Consoli, A.9
Bonomini, M.10
-
114
-
-
0029817966
-
Increased erythrocyte phosphatidylserine exposure in sickle cell disease: Flowcytometric measurement and clinical associations
-
Wood BL, Gibson DF, Tait JF. Increased erythrocyte phosphatidylserine exposure in sickle cell disease: flowcytometric measurement and clinical associations. Blood 1996; 88: 1873-1880
-
(1996)
Blood
, vol.88
, pp. 1873-1880
-
-
Wood, B.L.1
Gibson, D.F.2
Tait, J.F.3
|