Hippocampal microglial activation and glucocorticoid receptor down-regulation precipitate visceral hypersensitivity induced by colorectal distension in rats

Neuropharmacology

Volumn 102, Issue , 2016, Pages 295-303

  Zhang, Gongliang ^b   Zhao, Bing Xue ^a   Hua, Rong ^c   Kang, Jie ^a   Shao, Bo Ming ^a   Carbonaro, Theresa M ^d   Zhang, Yong Mei ^a  

^a XUZHOU MEDICAL UNIVERSITY   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

^c 97th Hospital of PLA   (China)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Glucocorticoid receptor; Hippocampus; Irritable bowel syndrome; Microglia; Visceral hypersensitivity

Indexed keywords

GLUCOCORTICOID RECEPTOR; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR;

ABDOMINAL DISEASE; ADULT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; BIOACCUMULATION; BRAIN LEVEL; CELL ACTIVATION; CELL COMPARTMENTALIZATION; CELLULAR DISTRIBUTION; COLORECTAL DISEASE; COLORECTAL DISTENTION; CONTROLLED STUDY; DEPRESSION; DISEASE ACTIVITY; DISEASE PREDISPOSITION; DOWN REGULATION; IMMUNOFLUORESCENCE; LEARNING DISORDER; MALE; MICROGLIA; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; VISCERAL HYPERSENSITIVITY; ANIMAL; COLON; DISEASE MODEL; GENETICS; HIPPOCAMPUS; METABOLISM; RECTUM; SPRAGUE DAWLEY RAT; VISCERAL PAIN;

ANIMALS; COLON; DISEASE MODELS, ANIMAL; DOWN-REGULATION; HIPPOCAMPUS; INTERLEUKIN-1BETA; MALE; MICROGLIA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUCOCORTICOID; RECTUM; TUMOR NECROSIS FACTOR-ALPHA; VISCERAL PAIN;

EID: 84949550400     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2015.11.028     Document Type: Article

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