Altered brain activation to colorectal distention in visceral hypersensitive maternal-separated rats

Neurogastroenterology and Motility

Volumn 24, Issue 7, 2012, Pages

  Wouters, M M ^a   Van Wanrooy, S ^a   Casteels, C ^b,c   Nemethova, A ^a   de Vries, A ^a   Van Oudenhove, L ^a   Van den Wijngaard, R M ^d   Van Laere, K ^b,c   Boeckxstaens, G ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b KU Leuven   (Belgium)

^c UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Brain mapping; Hippocampus; Nociception; Periaqueductal gray; Somatosensory cortex

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN REGION; CEREBELLUM; COLORECTAL DISTENTION; DIGESTIVE SYSTEM DISEASE; ELECTROMYOGRAPHY; FRONTAL CORTEX; HIPPOCAMPUS; IN VIVO STUDY; INTESTINE DISTENSION; MALE; MATERNAL DEPRIVATION; NONHUMAN; PERIAQUADUCTAL GRAY; PRIORITY JOURNAL; RAT; SOMATOSENSORY CORTEX; STRESS; VISCERAL HYPERSENSITIVITY; VISCERAL PAIN;

ANIMALS; BRAIN; DILATATION, PATHOLOGIC; ELECTROMYOGRAPHY; FEMALE; HYPERALGESIA; INTESTINES; MATERNAL DEPRIVATION; POSITRON-EMISSION TOMOGRAPHY; RATS; RATS, LONG-EVANS; STRESS, PSYCHOLOGICAL; VISCERAL PAIN;

EID: 84862675770     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2012.01919.x     Document Type: Article

References (37)

1. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology 2006; 130: 1480-91.
2. Mertz H, Naliboff B, Munakata J, Niazi N, Mayer EA. Altered rectal perception is a biological marker of patients with irritable bowel syndrome. Gastroenterology 1995; 109: 40-52.
3. Gebhart GF. Pathobiology of visceral pain: molecular mechanisms and therapeutic implications: IV. Visceral afferent contributions to the pathobiology of visceral pain. Am J Physiol Gastrointest Liver Physiol 2000; 278: G834-8.
4. Tillisch K, Labus JS. Advances in imaging the brain-gut axis: functional gastrointestinal disorders. Gastroenterology 2011; 140: 407-11.
5. Rapps N, van Oudenhove L, Enck P, Aziz Q. Brain imaging of visceral functions in healthy volunteers and IBS patients. J Psychosom Res 2008; 64: 599-604.
6. Mayer EA, Berman S, Suyenobu B et al. Differences in brain responses to visceral pain between patients with irritable bowel syndrome and ulcerative colitis. Pain 2005; 115: 398-409.
7. Elsenbruch S, Rosenberger C, Bingel U, Forsting M, Schedlowski M, Gizewski ER. Patients with irritable bowel syndrome have altered emotional modulation of neural responses to visceral stimuli. Gastroenterology 2010; 139: 1310-9.
8. Elsenbruch S, Rosenberger C, Enck P, Forsting M, Schedlowski M, Gizewski ER. Affective disturbances modulate the neural processing of visceral pain stimuli in irritable bowel syndrome: an fMRI study. Gut 2009; 59: 489-95.
9. McEwen BS. Glucocorticoids, depression, and mood disorders: structural remodeling in the brain. Metabolism 2005; 54: 20-3.
10. Oakley Browne MA, Joyce PR, Wells JE, Bushnell JA, Hornblow AR. Disruptions in childhood parental care as risk factors for major depression in adult women. Aust N Z J Psychiatry 1995; 29: 437-48.
11. Heim C, Nemeroff CB. The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies. Biol Psychiatry 2001; 49: 1023-39.
12. Drossman DA. Abuse, trauma, and GI illness: is there a link? Am J Gastroenterol 2011; 106: 14-25.
13. Oitzl MS, Workel JO, Fluttert M, Frosch F, De Kloet ER. Maternal deprivation affects behaviour from youth to senescence: amplification of individual differences in spatial learning and memory in senescent Brown Norway rats. Eur J Neurosci 2000; 12: 3771-80.
14. Sanchez MM, Ladd CO, Plotsky PM. Early adverse experience as a developmental risk factor for later psychopathology: evidence from rodent and primate models. Dev Psychopathol 2001; 13: 419-49.
15. Welting O, van den Wijngaard RM, de Jonge WJ, Holman R, Boeckxstaens GE. Assessment of visceral sensitivity using radio telemetry in a rat model of maternal separation. Neurogastroenterol Motil 2005; 17: 838-45.
16. Coutinho SV, Plotsky PM, Sablad M et al. Neonatal maternal separation alters stress-induced responses to viscerosomatic nociceptive stimuli in rat. Am J Physiol Gastrointest Liver Physiol 2002; 282: G307-16.
17. Gibney SM, Gosselin RD, Dinan TG, Cryan JF. Colorectal distension-induced prefrontal cortex activation in the Wistar-Kyoto rat: implications for irritable bowel syndrome. Neuroscience 2010; 165: 675-83.
18. Chung EK, Zhang X, Li Z, Zhang H, Xu H, Bian Z. Neonatal maternal separation enhances central sensitivity to noxious colorectal distention in rat. Brain Res 2007; 1153: 68-77.
19. Lazovic J, Wrzos HF, Yang QX et al. Regional activation in the rat brain during visceral stimulation detected by c-fos expression and fMRI. Neurogastroenterol Motil 2005; 17: 548-56.
20. Wang Z, Bradesi S, Maarek JM et al. Regional brain activation in conscious, nonrestrained rats in response to noxious visceral stimulation. Pain 2008; 138: 233-43.
21. Johnson AC, Myers B, lazovic J, Towner R, Greenwood-van MB. Brain activation in response to visceral stimulation in rats with amygdala implants of corticosterone: an FMRI study. PLoS ONE 2010; 5: e8573.
22. Christianson JA, Gebhart GF. Assessment of colon sensitivity by luminal distension in mice. Nat Protoc 2007; 2: 2624-31.
23. Alonso BC, Makarova T, Hess A. On the use of alpha-chloralose for repeated BOLD fMRI measurements in rats. J Neurosci Methods 2011; 195: 236-40.
24. Fox PT, Mintun MA, Raichle ME, Miezin FM, Allman JM, Van Essen DC. Mapping human visual cortex with positron emission tomography. Nature 1986; 323: 806-9.
25. Schweinhardt P, Fransson P, Olson L, Spenger C, Andersson JL. A template for spatial normalisation of MR images of the rat brain. J Neurosci Methods 2003; 129: 105-13.
26. Casteels C, Vermaelen P, Nuyts J et al. Construction and evaluation of multitracer small-animal PET probabilistic atlases for voxel-based functional mapping of the rat brain. J Nucl Med 2006; 47: 1858-66.
27. Barreau F, Ferrier L, Fioramonti J, Bueno L. Neonatal maternal deprivation triggers long term alterations in colonic epithelial barrier and mucosal immunity in rats. Gut 2004; 53: 501-6.
28. Petrovic P, Ingvar M. Imaging cognitive modulation of pain processing. Pain 2002; 95: 1-5.
29. Rosenberger C, Elsenbruch S, Scholle A et al. Effects of psychological stress on the cerebral processing of visceral stimuli in healthy women. Neurogastroenterol Motil 2009; 21: 740-e45.
30. Van Oudenhove L, Vandenberghe J, Dupont P et al. Cortical deactivations during gastric fundus distension in health: visceral pain-specific response or attenuation of 'default mode' brain function? A H2 15O-PET study. Neurogastroenterol Motil 2009; 21: 259-71.
31. Bremner JD, Randall P, Vermetten E et al. Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse - a preliminary report. Biol Psychiatry 1997; 41: 23-32.
32. Bremner JD, Vythilingam M, Vermetten E et al. MRI and PET study of deficits in hippocampal structure and function in women with childhood sexual abuse and posttraumatic stress disorder. Am J Psychiatry 2003; 160: 924-32.
33. Van Oudenhove L, Vandenberghe J, Dupont P et al. Regional brain activity in functional dyspepsia: a H(2)(15)O-PET study on the role of gastric sensitivity and abuse history. Gastroenterology 2010; 139: 36-47.
34. Simmons AN, Stein MB, Strigo IA, Arce E, Hitchcock C, Paulus MP. Anxiety positive subjects show altered processing in the anterior insula during anticipation of negative stimuli. Hum Brain Mapp 2011; 32(11): 1836-46.
35. Naliboff BD, Mayer EA. Brain imaging in IBS: drawing the line between cognitive and non-cognitive processes. Gastroenterology 2006; 130: 267-70.
36. Burns HD, van LK, Sanabria-Bohorquez S et al. [18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor. Proc Natl Acad Sci U S A 2007; 104: 9800-5.
37. Niddam DM, Tsai SY, Lu CL, Ko CW, Hsieh JC. Reduced hippocampal glutamate-glutamine levels in irritable bowel syndrome: preliminary findings using magnetic resonance spectroscopy. Am J Gastroenterol 2011; 106: 1503-11.