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Volumn 6, Issue 5-6, 2015, Pages 220-230

CArG-driven GADD45α activated by resveratrol inhibits lung cancer cells

Author keywords

CArG elements; Egr 1; GADD45 ; Gene therapy; Resveratrol; Synthetic promoters

Indexed keywords

GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45 ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; RESVERATROL; TRANSCRIPTION FACTOR EGR 1; UNCLASSIFIED DRUG;

EID: 84949548949     PISSN: 19476019     EISSN: 19476027     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (12)

References (42)
  • 3
    • 84934436555 scopus 로고    scopus 로고
    • Gadd45 in stress signaling, cell cycle control, and apoptosis
    • Salvador JM, Brown-Clay JD, Fornace AJ. Gadd45 in stress signaling, cell cycle control, and apoptosis. Adv Exp Med Biol. 2013; 793: 1-19.
    • (2013) Adv Exp Med Biol , vol.793 , pp. 1-19
    • Salvador, J.M.1    Brown-Clay, J.D.2    Fornace, A.J.3
  • 4
    • 22044442810 scopus 로고    scopus 로고
    • Gene therapy vectors containing CArG elements from the Egr1 gene are activated by neutron irradiation, cisplatin and doxorubicin
    • Greco O, Powell TM, Marples B, Joiner MC, Scott SD. Gene therapy vectors containing CArG elements from the Egr1 gene are activated by neutron irradiation, cisplatin and doxorubicin. Cancer Gene Ther. 2005; 12: 655-662.
    • (2005) Cancer Gene Ther , vol.12 , pp. 655-662
    • Greco, O.1    Powell, T.M.2    Marples, B.3    Joiner, M.C.4    Scott, S.D.5
  • 5
    • 0033529121 scopus 로고    scopus 로고
    • Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53- regulated protein Gadd45
    • Zhan Q, Antinore MJ, Wang XW, Carrier F, Smith ML, Harris CC, Fornace AJ Jr. Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53- regulated protein Gadd45. Oncogene. 1999; 18: 2892-2900.
    • (1999) Oncogene , vol.18 , pp. 2892-2900
    • Zhan, Q.1    Antinore, M.J.2    Wang, X.W.3    Carrier, F.4    Smith, M.L.5    Harris, C.C.6    Fornace, A.J.7
  • 6
    • 0032514967 scopus 로고    scopus 로고
    • A family of stress-inducible GADD45-like proteins mediate activation of the stressresponsive MTK1/MEKK4 MAPKKK
    • Takekawa M, Saito H. A family of stress-inducible GADD45-like proteins mediate activation of the stressresponsive MTK1/MEKK4 MAPKKK. Cell. 1998; 95: 521–530.
    • (1998) Cell , vol.95 , pp. 521-530
    • Takekawa, M.1    Saito, H.2
  • 7
    • 84874786609 scopus 로고    scopus 로고
    • Gadd45a suppresses tumor angiogenesis via inhibition of the mTOR/STAT3 protein pathway
    • Yang F, Zhang W, Li D, Zhan Q. Gadd45a suppresses tumor angiogenesis via inhibition of the mTOR/STAT3 protein pathway. J Biol Chem. 2013; 288: 6552-6560.
    • (2013) J Biol Chem , vol.288 , pp. 6552-6560
    • Yang, F.1    Zhang, W.2    Li, D.3    Zhan, Q.4
  • 9
    • 43249116904 scopus 로고    scopus 로고
    • Decitabine-induced demethylation of 5’ CpG island in GADD45A leads to apoptosis in osteosarcoma cells
    • Al-Romaih K, Sadikovic B, Yoshimoto M, Wang Y, Zielenska M, Squire JA. Decitabine-induced demethylation of 5’ CpG island in GADD45A leads to apoptosis in osteosarcoma cells. Neoplasia. 2008; 10: 471-480.
    • (2008) Neoplasia , vol.10 , pp. 471-480
    • Al-Romaih, K.1    Sadikovic, B.2    Yoshimoto, M.3    Wang, Y.4    Zielenska, M.5    Squire, J.A.6
  • 10
    • 25144508812 scopus 로고    scopus 로고
    • GADD45 deregulation in cancer: Frequently methylated tumor suppressors and potential therapeutic targets
    • Zerbini LF, Libermann TA. GADD45 deregulation in cancer: frequently methylated tumor suppressors and potential therapeutic targets. Clin Cancer Res. 2005; 11: 6409–6413.
    • (2005) Clin Cancer Res , vol.11 , pp. 6409-6413
    • Zerbini, L.F.1    Libermann, T.A.2
  • 12
    • 21044444012 scopus 로고    scopus 로고
    • Gadd45a expression induces Bim dissociation from the cytoskeleton and translocation to mitochondria
    • Tong T, Ji J, Jin S, Li X, Fan W, Song Y, Wang M, Liu Z, Wu M, Zhan Q. Gadd45a expression induces Bim dissociation from the cytoskeleton and translocation to mitochondria. Mol Cell Biol. 2005; 25: 4488–4500.
    • (2005) Mol Cell Biol , vol.25 , pp. 4488-4500
    • Tong, T.1    Ji, J.2    Jin, S.3    Li, X.4    Fan, W.5    Song, Y.6    Wang, M.7    Liu, Z.8    Wu, M.9    Zhan, Q.10
  • 13
    • 0025317094 scopus 로고
    • Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals
    • Cao XM, Koski RA, Gashler A, McKiernan M, Morris CF, Gaffney R, Hay RV, Sukhatme VP. Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals. Mol Cell Biol. 1990; 10: 1931-1939.
    • (1990) Mol Cell Biol , vol.10 , pp. 1931-1939
    • Cao, X.M.1    Koski, R.A.2    Gashler, A.3    McKiernan, M.4    Morris, C.F.5    Gaffney, R.6    Hay, R.V.7    Sukhatme, V.P.8
  • 16
    • 0031458309 scopus 로고    scopus 로고
    • Egr-1 is activated in endothelial cells exposed to fluid shear stress and interacts with a novel shear-stress-response element in the PDGF A-chain promoter
    • Khachigian LM, Anderson KR, Halnon NJ, Gimbrone MA Jr, Resnick N, Collins T. Egr-1 is activated in endothelial cells exposed to fluid shear stress and interacts with a novel shear-stress-response element in the PDGF A-chain promoter. Arterioscler Thromb Vasc Biol. 1997; 17: 2280-2286.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 2280-2286
    • Khachigian, L.M.1    Erson, K.R.2    Halnon, N.J.3    Gimbrone, M.A.4    Resnick, N.5    Collins, T.6
  • 17
    • 84903514037 scopus 로고    scopus 로고
    • Sequential activation of Elk-1/Egr-1/GADD45α by arsenic
    • Shi Q, Sutariya V, Bishayee A, Bhatia D. Sequential activation of Elk-1/Egr-1/GADD45α by arsenic. Oncotarget. 2014; 5: 3862-3870.
    • (2014) Oncotarget , vol.5 , pp. 3862-3870
    • Shi, Q.1    Sutariya, V.2    Bishayee, A.3    Bhatia, D.4
  • 18
    • 0029559345 scopus 로고
    • Activation of the radiosensitive EGR-1 promoter induces expression of the herpes simplex virus thymidine kinase gene and sensitivity of human glioma cells to ganciclovir
    • Joki T, Nakamura M, Ohno T. Activation of the radiosensitive EGR-1 promoter induces expression of the herpes simplex virus thymidine kinase gene and sensitivity of human glioma cells to ganciclovir. Hum Gene Ther. 1995; 6: 1507-1513.
    • (1995) Hum Gene Ther , vol.6 , pp. 1507-1513
    • Joki, T.1    Nakamura, M.2    Ohno, T.3
  • 20
    • 0036773207 scopus 로고    scopus 로고
    • Optimizing radiationresponsive gene promoters for radiogenetic cancer therapy
    • Scott SD, Joiner MC, Marples B. Optimizing radiationresponsive gene promoters for radiogenetic cancer therapy. Gene Ther. 2002; 9: 1396-1402.
    • (2002) Gene Ther , vol.9 , pp. 1396-1402
    • Scott, S.D.1    Joiner, M.C.2    Marples, B.3
  • 24
    • 22844450866 scopus 로고    scopus 로고
    • Resveratrol as an anticancer nutrient: Molecular basis, open questions and promises
    • Signorelli P, Ghidoni R. Resveratrol as an anticancer nutrient: molecular basis, open questions and promises. J Nutr Biochem. 2005; 16: 449-466.
    • (2005) J Nutr Biochem , vol.16 , pp. 449-466
    • Signorelli, P.1    Ghidoni, R.2
  • 27
    • 78650822083 scopus 로고    scopus 로고
    • Resveratrol-induced apoptosis is mediated by early growth response-1, Krüppel-like factor 4, and activating transcription factor 3
    • Whitlock NC, Bahn JH, Lee SH, Eling TE, Baek SJ. Resveratrol-induced apoptosis is mediated by early growth response-1, Krüppel-like factor 4, and activating transcription factor 3. Cancer Prev Res (Phila). 2011; 4: 116-127.
    • (2011) Cancer Prev Res (Phila) , vol.4 , pp. 116-127
    • Whitlock, N.C.1    Bahn, J.H.2    Lee, S.H.3    Eling, T.E.4    Baek, S.J.5
  • 28
    • 0029125757 scopus 로고
    • Integration of MAP kinase signal transduction pathways at the serum response element
    • Whitmarsh AJ, Shore P, Sharrocks AD, Davis RJ. Integration of MAP kinase signal transduction pathways at the serum response element. Science. 1995; 269: 403-407.
    • (1995) Science , vol.269 , pp. 403-407
    • Whitmarsh, A.J.1    Shore, P.2    Sharrocks, A.D.3    Davis, R.J.4
  • 29
    • 0036962164 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis in thyroid cancer cell lines via a MAPK- and p53-dependent mechanism
    • Shih A, Davis FB, Lin HY, Davis PJ. Resveratrol induces apoptosis in thyroid cancer cell lines via a MAPK- and p53-dependent mechanism. J Clin Endocrinol Metab. 2002; 87: 1223-1232.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1223-1232
    • Shih, A.1    Davis, F.B.2    Lin, H.Y.3    Davis, P.J.4
  • 30
    • 0035866404 scopus 로고    scopus 로고
    • Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase
    • She QB, Bode AM, Ma WY, Chen NY, Dong Z. Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase. Cancer Res. 2001; 61: 1604-1610.
    • (2001) Cancer Res , vol.61 , pp. 1604-1610
    • She, Q.B.1    Bode, A.M.2    Ma, W.Y.3    Chen, N.Y.4    Dong, Z.5
  • 31
    • 84868645464 scopus 로고    scopus 로고
    • Transcriptional regulation of EGR1 by EGF and the ERK signaling pathway in prostate cancer cells
    • Gregg J, Fraizer G. Transcriptional regulation of EGR1 by EGF and the ERK signaling pathway in prostate cancer cells. Genes Cancer. 2011; 2: 900-909.
    • (2011) Genes Cancer , vol.2 , pp. 900-909
    • Gregg, J.1    Fraizer, G.2
  • 32
    • 13244265558 scopus 로고    scopus 로고
    • NF-kappaB/Egr-1/Gadd45 are sequentially activated upon UVB irradiation to mediate epidermal cell death
    • Thyss R, Virolle V, Imbert V, Peyron JF, Aberdam D, Virolle T. NF-kappaB/Egr-1/Gadd45 are sequentially activated upon UVB irradiation to mediate epidermal cell death. EMBO J. 2005; 24: 128-137.
    • (2005) EMBO J , vol.24 , pp. 128-137
    • Thyss, R.1    Virolle, V.2    Imbert, V.3    Peyron, J.F.4    Aberdam, D.5    Virolle, T.6
  • 33
    • 0344406281 scopus 로고    scopus 로고
    • The egr-1 gene is induced by DNA-damaging agents and non-genotoxic drugs in both normal and neoplastic human cells
    • Quiñones A, Dobberstein KU, Rainov NG. The egr-1 gene is induced by DNA-damaging agents and non-genotoxic drugs in both normal and neoplastic human cells. Life Sci. 2003; 72: 2975-2992.
    • (2003) Life Sci , vol.72 , pp. 2975-2992
    • Quiñones, A.1    Dobberstein, K.U.2    Rainov, N.G.3
  • 34
    • 0033569918 scopus 로고    scopus 로고
    • Stress-induced JNK activation is independent of Gadd45 induction
    • Shaulian E, Karin M. Stress-induced JNK activation is independent of Gadd45 induction. J Biol Chem. 1999; 274: 29595-29598.
    • (1999) J Biol Chem , vol.274 , pp. 29595-29598
    • Shaulian, E.1    Karin, M.2
  • 36
    • 0035866787 scopus 로고    scopus 로고
    • Dimethylbenzanthracene carcinogenesis in Gadd45a-null mice is associated with decreased DNA repair andincreased mutation frequency
    • Hollander MC, Kovalsky O, Salvador JM, Kim KE, Patterson AD, Haines DC, Fornace AJ . Dimethylbenzanthracene carcinogenesis in Gadd45a-null mice is associated with decreased DNA repair andincreased mutation frequency. Cancer Res. 2001; 61: 2487-2491.
    • (2001) Cancer Res , vol.61 , pp. 2487-2491
    • Hollander, M.C.1    Kovalsky, O.2    Salvador, J.M.3    Kim, K.E.4    Patterson, A.D.5    Haines, D.C.6    Fornace, A.J.7
  • 37
    • 59449098863 scopus 로고    scopus 로고
    • Adenoviral-mediated gene transfer of Gadd45a results in suppression by inducing apoptosis and cell cycle arrest in pancreatic cancer cell
    • Li Y, Qian H, Li X, Wang H, Yu J, Liu Y, Zhang X, Liang X, Fu M, Zhan Q, Lin C. Adenoviral-mediated gene transfer of Gadd45a results in suppression by inducing apoptosis and cell cycle arrest in pancreatic cancer cell. J Gene Med. 2009; 11: 3-13.
    • (2009) J Gene Med , vol.11 , pp. 3-13
    • Li, Y.1    Qian, H.2    Li, X.3    Wang, H.4    Yu, J.5    Liu, Y.6    Zhang, X.7    Liang, X.8    Fu, M.9    Zhan, Q.10    Lin, C.11
  • 39
    • 0042520999 scopus 로고    scopus 로고
    • Zappia V. P21Cip1 gene expression is modulated by Egr1: A novel regulatory mechanism involved in the resveratrol antiproliferative effect
    • Ragione FD, Cucciolla V, Criniti V, Indaco S, Borriello A, Zappia V. p21Cip1 gene expression is modulated by Egr1: a novel regulatory mechanism involved in the resveratrol antiproliferative effect. J Biol Chem. 2003; 278: 23360-23368.
    • (2003) J Biol Chem , vol.278 , pp. 23360-23368
    • Ragione, F.D.1    Cucciolla, V.2    Criniti, V.3    Indaco, S.4    Borriello, A.5
  • 40
    • 79958120468 scopus 로고    scopus 로고
    • GADD45α and annexin A1 are involved in the apoptosis of HL-60 induced by resveratrol
    • Li G, He S, Chang L, Lu H, Zhang H, Zhang H, Chiu J. GADD45α and annexin A1 are involved in the apoptosis of HL-60 induced by resveratrol. Phytomedicine. 2011; 18: 704-709.
    • (2011) Phytomedicine , vol.18 , pp. 704-709
    • Li, G.1    He, S.2    Chang, L.3    Lu, H.4    Zhang, H.5    Zhang, H.6    Chiu, J.7
  • 41
    • 67651115664 scopus 로고    scopus 로고
    • Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers
    • Weichselbaum RR, Kufe D. Translation of the radio- and chemo-inducible TNFerade vector to the treatment of human cancers. Cancer Gene Ther. 2009; 16: 609-619.
    • (2009) Cancer Gene Ther , vol.16 , pp. 609-619
    • Weichselbaum, R.R.1    Kufe, D.2
  • 42
    • 0042807479 scopus 로고    scopus 로고
    • Combined radiation and cytochrome CYP4B1/4-ipomeanol gene therapy using the EGR1 promoter
    • Hsu H, Rainov NG, Quinones A, Eling DJ, Sakamoto KM, Spear MA. Combined radiation and cytochrome CYP4B1/4-ipomeanol gene therapy using the EGR1 promoter. Anticancer Res. 2003; 23: 2723-2728.
    • (2003) Anticancer Res , vol.23 , pp. 2723-2728
    • Hsu, H.1    Rainov, N.G.2    Quinones, A.3    Eling, D.J.4    Sakamoto, K.M.5    Spear, M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.