-
1
-
-
64349116712
-
Interactions between PTEN and receptor tyrosine kinase pathways and their implications for glioma therapy
-
Abounader R. Interactions between PTEN and receptor tyrosine kinase pathways and their implications for glioma therapy. Expert Rev. Anticancer Ther. 2009;9:235-15.
-
(2009)
Expert Rev. Anticancer Ther
, vol.9
, pp. 235-315
-
-
Abounader, R.1
-
2
-
-
6944251954
-
Molecular targeting for malignant gliomas (Review)
-
Kondo Y, Hollingsworth EF, Kondo S. Molecular targeting for malignant gliomas (Review). Int. J. Oncol. 2004;24:1101-9.
-
(2004)
Int. J. Oncol
, vol.24
, pp. 1101-1109
-
-
Kondo, Y.1
Hollingsworth, E.F.2
Kondo, S.3
-
3
-
-
79958087774
-
Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma
-
Cin H, Meyer C, Herr R, Janzarik WG, Lambert S, Jones DTW, Jacob K, Benner A, Witt H, Remke M, Bender S, Falkenstein F, Van Anh TN, et al. Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma. Acta Neuropathol. 2011;121:763-74.
-
(2011)
Acta Neuropathol
, vol.121
, pp. 763-774
-
-
Cin, H.1
Meyer, C.2
Herr, R.3
Janzarik, W.G.4
Lambert, S.5
Jones, D.6
Jacob, K.7
Benner, A.8
Witt, H.9
Remke, M.10
Bender, S.11
Falkenstein, F.12
Van Anh, T.N.13
-
4
-
-
67349219657
-
Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma. Oncogene
-
Jones DTW, Kocialkowski S, Liu L, Pearson DM, Ichimura K, Collins VP. Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma. Oncogene. Nature Publishing Group; 2009;28:2119-23.
-
(2009)
Nature Publishing Group
, vol.28
, pp. 2119-2123
-
-
Jones, D.1
Kocialkowski, S.2
Liu, L.3
Pearson, D.M.4
Ichimura, K.5
Collins, V.P.6
-
5
-
-
66849099801
-
Activation of the ERK/ MAPK pathway: A signature genetic defect in posterior fossa pilocytic astrocytomas
-
Forshew T, Tatevossian RG, Lawson ARJ, Ma J, Neale G, Ogunkolade BW, Jones TA, Aarum J, Dalton J, Bailey S, Chaplin T, Carter RL, Gajjar A, et al. Activation of the ERK/ MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas. J. Pathol. 2009;218:172-81.
-
(2009)
J. Pathol
, vol.218
, pp. 172-181
-
-
Forshew, T.1
Tatevossian, R.G.2
Lawson, A.3
Ma, J.4
Neale, G.5
Ogunkolade, B.W.6
Jones, T.A.7
Aarum, J.8
Dalton, J.9
Bailey, S.10
Chaplin, T.11
Carter, R.L.12
Gajjar, A.13
-
6
-
-
55349107544
-
Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas
-
Jones DTW, Kocialkowski S, Liu L, Pearson DM, Backlund LM, Ichimura K, Collins VP. Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas. Cancer Res. 2008;68:8673-7.
-
(2008)
Cancer Res
, vol.68
, pp. 8673-8677
-
-
Jones, D.1
Kocialkowski, S.2
Liu, L.3
Pearson, D.M.4
Backlund, L.M.5
Ichimura, K.6
Collins, V.P.7
-
7
-
-
66949147222
-
A. Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene
-
Sievert AJ, Jackson EM, Gai X, Hakonarson H, Judkins AR, Resnick AC, Sutton LN, Storm PB, Shaikh TH, Biegel J a. Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. Brain Pathol. 2009;19:449-58.
-
(2009)
Brain Pathol
, vol.19
, pp. 449-458
-
-
Sievert, A.J.1
Jackson, E.M.2
Gai, X.3
Hakonarson, H.4
Judkins, A.R.5
Resnick, A.C.6
Sutton, L.N.7
Storm, P.B.8
Shaikh, T.H.9
Biegel, J.10
-
8
-
-
73649119176
-
MAPK pathway activation and the origins of pediatric low-grade astrocytomas
-
Tatevossian RG, Lawson ARJ, Forshew T, Hindley GFL, Ellison DW, Sheer D. MAPK pathway activation and the origins of pediatric low-grade astrocytomas. J. Cell. Physiol. 2010;222:509-14.
-
(2010)
J. Cell. Physiol
, vol.222
, pp. 509-514
-
-
Tatevossian, R.G.1
Lawson, A.2
Forshew, T.3
Hindley, G.4
Ellison, D.W.5
Sheer, D.6
-
9
-
-
77957275728
-
RAF gene fusions are specific to pilocytic astrocytoma in a broad paediatric brain tumour cohort
-
Lawson ARJ, Tatevossian RG, Phipps KP, Picker SR, Michalski A, Sheer D, Jacques TS, Forshew T. RAF gene fusions are specific to pilocytic astrocytoma in a broad paediatric brain tumour cohort. Acta Neuropathol. 2010;120:271-3.
-
(2010)
Acta Neuropathol
, vol.120
, pp. 271-273
-
-
Lawson, A.1
Tatevossian, R.G.2
Phipps, K.P.3
Picker, S.R.4
Michalski, A.5
Sheer, D.6
Jacques, T.S.7
Forshew, T.8
-
10
-
-
84870506967
-
Pediatric glioma-associated KIAA1549:BRAF expression regulates neuroglial cell growth in a cell type-specific and mTOR-dependent manner
-
Kaul A, Chen Y-H, Emnett RJ, Dahiya S, Gutmann DH. Pediatric glioma-associated KIAA1549:BRAF expression regulates neuroglial cell growth in a cell type-specific and mTOR-dependent manner. Genes Dev. 2012;26:2561-6.
-
(2012)
Genes Dev
, vol.26
, pp. 2561-2566
-
-
Kaul, A.1
Chen, Y.-H.2
Emnett, R.J.3
Dahiya, S.4
Gutmann, D.H.5
-
11
-
-
79953308458
-
An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice
-
Gronych J, Korshunov A, Bageritz J, Milde T, Jugold M, Hambardzumyan D, Remke M, Hartmann C, Witt H, Jones DTW, Witt O, Heiland S, Bendszus M, et al. An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice. J. Clin. Invest. 2011;121:1344-8.
-
(2011)
J. Clin. Invest
, vol.121
, pp. 1344-1348
-
-
Gronych, J.1
Korshunov, A.2
Bageritz, J.3
Milde, T.4
Jugold, M.5
Hambardzumyan, D.6
Remke, M.7
Hartmann, C.8
Witt, H.9
Jones, D.10
Witt, O.11
Heiland, S.12
Bendszus, M.13
-
12
-
-
84878723078
-
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas
-
Zhang J, Wu G, Miller CP, Tatevossian RG, Dalton JD, Tang B, Orisme W, Punchihewa C, Parker M, Qaddoumi I, Boop F, Lu C, Kandoth C, et al. Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat. Genet. 2013;45:602-12.
-
(2013)
Nat. Genet
, vol.45
, pp. 602-612
-
-
Zhang, J.1
Wu, G.2
Miller, C.P.3
Tatevossian, R.G.4
Dalton, J.D.5
Tang, B.6
Orisme, W.7
Punchihewa, C.8
Parker, M.9
Qaddoumi, I.10
Boop, F.11
Lu, C.12
Kandoth, C.13
-
13
-
-
76549137130
-
Mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas
-
Schiffman JD, Hodgson JG, VandenBerg SR, Flaherty P, Polley M-YC, Yu M, Fisher PG, Rowitch DH, Ford JM, Berger MS, Ji H, Gutmann DH, James CD. Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas. Cancer Res. 2010;70:512-9.
-
(2010)
Cancer Res
, vol.70
, pp. 512-519
-
-
Schiffman, J.D.1
Hodgson, J.G.2
Vandenberg, S.R.3
Flaherty, P.4
Polley, M.-Y.5
Yu, M.6
Fisher, P.G.7
Rowitch, D.H.8
Ford, J.M.9
Berger, M.S.10
Ji, H.11
Gutmann, D.H.12
James, C.D.13
Oncogenic, B.14
-
14
-
-
0031710479
-
A. The INK4a/ARF tumor suppressor: One gene--two products-two pathways
-
Chin L, Pomerantz J, DePinho R a. The INK4a/ARF tumor suppressor: one gene--two products-two pathways. Trends Biochem. Sci. 1998;23:291-6.
-
(1998)
Trends Biochem. Sci
, vol.23
, pp. 291-296
-
-
Chin, L.1
Pomerantz, J.2
Depinho, R.3
-
15
-
-
0033588882
-
The INK4 family of cell cycle inhibitors in cancer
-
Roussel MF. The INK4 family of cell cycle inhibitors in cancer. Oncogene. 1999;18:5311-7.
-
(1999)
Oncogene
, vol.18
, pp. 5311-5317
-
-
Roussel, M.F.1
-
16
-
-
75149150689
-
Induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation. Oncogene
-
Robinson JP, VanBrocklin MW, Guilbeault a R, Signorelli DL, Brandner S, Holmen SL. Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation. Oncogene. Nature Publishing Group; 2010;29:335-44.
-
(2010)
Nature Publishing Group
, vol.29
, pp. 335-344
-
-
Robinson, J.P.1
Vanbrocklin, M.W.2
Guilbeault A, R.3
Signorelli, D.L.4
Brandner, S.5
Holmen, S.L.6
Activated, B.7
-
17
-
-
84878144473
-
Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas
-
Sievert AJ, Lang S, Katie L, Madsen PJ, Slaunwhite E, Choudhari N, Kellet M, Storm PB, Resnick AC, Kjetland EF, Atkins KE, Poolman EM, Evan W, et al. Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas. Proc. Natl. Acad. Sci. 2013;110:8750-8750.
-
(2013)
Proc. Natl. Acad. Sci
, vol.110
, pp. 8750-8751
-
-
Sievert, A.J.1
Lang, S.2
Katie, L.3
Madsen, P.J.4
Slaunwhite, E.5
Choudhari, N.6
Kellet, M.7
Storm, P.B.8
Resnick, A.C.9
Kjetland, E.F.10
Atkins, K.E.11
Poolman, E.M.12
Evan, W.13
-
18
-
-
78651061485
-
MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas
-
Tatevossian RG, Tang B, Dalton J, Forshew T, Lawson AR, Ma J, Neale G, Shurtleff SA, Bailey S, Gajjar A, Baker SJ, Sheer D, Ellison DW. MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas. Acta Neuropathol. 2010;120:731-43.
-
(2010)
Acta Neuropathol
, vol.120
, pp. 731-743
-
-
Tatevossian, R.G.1
Tang, B.2
Dalton, J.3
Forshew, T.4
Lawson, A.R.5
Ma, J.6
Neale, G.7
Shurtleff, S.A.8
Bailey, S.9
Gajjar, A.10
Baker, S.J.11
Sheer, D.12
Ellison, D.W.13
-
19
-
-
0029587551
-
A, Sherr CJ. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
-
Quelle DE, Zindy F, Ashmun R a, Sherr CJ. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell. 1995;83:993-1000.
-
(1995)
Cell
, vol.83
, pp. 993-1000
-
-
Quelle, D.E.1
Zindy, F.2
Ashmun, R.3
-
20
-
-
47249140412
-
Rutka JT. P14ARF interacts with DAXX: Effects on HDM2 and p53
-
Ivanchuk SM, Mondal S, Rutka JT. p14ARF interacts with DAXX: effects on HDM2 and p53. Cell Cycle. 2008;7:1836-50.
-
(2008)
Cell Cycle
, vol.7
, pp. 1836-1850
-
-
Ivanchuk, S.M.1
Mondal, S.2
-
21
-
-
77953020697
-
Association of molecular alterations, including BRAF, with biology and outcome in pilocytic astrocytomas
-
Horbinski C, Hamilton RL, Nikiforov Y, Pollack IF. Association of molecular alterations, including BRAF, with biology and outcome in pilocytic astrocytomas. Acta Neuropathol. 2010;119:641-9.
-
(2010)
Acta Neuropathol
, vol.119
, pp. 641-649
-
-
Horbinski, C.1
Hamilton, R.L.2
Nikiforov, Y.3
Pollack, I.F.4
-
22
-
-
84862193195
-
Interplay among BRAF, p16, p53, and MIB1 in pediatric low-grade gliomas
-
Horbinski C, Nikiforova MN, Hagenkord JM, Hamilton RL, Pollack IF. Interplay among BRAF, p16, p53, and MIB1 in pediatric low-grade gliomas. Neuro. Oncol. 2012;14:777-89.
-
(2012)
Neuro. Oncol
, vol.14
, pp. 777-789
-
-
Horbinski, C.1
Nikiforova, M.N.2
Hagenkord, J.M.3
Hamilton, R.L.4
Pollack, I.F.5
-
23
-
-
24944561382
-
Essential role for Ras signaling in glioblastoma maintenance
-
Holmen SL, Williams BO. Essential role for Ras signaling in glioblastoma maintenance. Cancer Res. 2005;65:8250-5.
-
(2005)
Cancer Res
, vol.65
, pp. 8250-8255
-
-
Holmen, S.L.1
Williams, B.O.2
-
25
-
-
0032168060
-
The EV-O-derived cell line DF-1 supports the efficient replication of avian leukosis-sarcoma viruses and vectors
-
Schaefer-Klein J, Givol I, Barsov E V, Whitcomb JM, VanBrocklin M, Foster DN, Federspiel MJ, Hughes SH. The EV-O-derived cell line DF-1 supports the efficient replication of avian leukosis-sarcoma viruses and vectors. Virology. 1998;248:305-11.
-
(1998)
Virology
, vol.248
, pp. 305-311
-
-
Schaefer-Klein, J.1
Givol, I.2
Barsov, E.V.3
Whitcomb, J.M.4
Vanbrocklin, M.5
Foster, D.N.6
Federspiel, M.J.7
Hughes, S.H.8
-
26
-
-
0018489146
-
An enzyme-linked immunosorbent assay for detecting avian leukosis-sarcoma viruses
-
Smith EJ, Fadly A, Okazaki W. An enzyme-linked immunosorbent assay for detecting avian leukosis-sarcoma viruses. Avian Dis. 23:698-707.
-
Avian Dis
, vol.23
, pp. 698-707
-
-
Smith, E.J.1
Fadly, A.2
Okazaki, W.3
-
27
-
-
79952758949
-
Cooperates with Ink4a/Arf loss or Akt activation to induce gliomas in vivo. Oncogene
-
Robinson JP, Vanbrocklin MW, Lastwika KJ, McKinney a J, Brandner S, Holmen SL. Activated MEK cooperates with Ink4a/Arf loss or Akt activation to induce gliomas in vivo. Oncogene. Nature Publishing Group; 2011;30:1341-50.
-
(2011)
Nature Publishing Group
, vol.30
, pp. 1341-1350
-
-
Robinson, J.P.1
Vanbrocklin, M.W.2
Lastwika, K.J.3
McKinney A, J.4
Brandner, S.5
Holmen, S.L.6
Activated, M.7
-
28
-
-
64049105206
-
Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system
-
Bacon C, Endris V, Rappold G. Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system. J. Comp. Neurol. 2009;513:224-36.
-
(2009)
J. Comp. Neurol
, vol.513
, pp. 224-236
-
-
Bacon, C.1
Endris, V.2
Rappold, G.3
-
29
-
-
33745280911
-
MEGAP impedes cell migration via regulating actin and microtubule dynamics and focal complex formation
-
Yang Y, Marcello M, Endris V, Saffrich R, Fischer R, Trendelenburg MF, Sprengel R, Rappold G. MEGAP impedes cell migration via regulating actin and microtubule dynamics and focal complex formation. Exp. Cell Res. 2006;312:2379-93.
-
(2006)
Exp. Cell Res
, vol.312
, pp. 2379-2393
-
-
Yang, Y.1
Marcello, M.2
Endris, V.3
Saffrich, R.4
Fischer, R.5
Trendelenburg, M.F.6
Sprengel, R.7
Rappold, G.8
-
30
-
-
84862900240
-
MAPK pathway activation in pilocytic astrocytoma
-
Jones DTW, Gronych J, Lichter P, Witt O, Pfister SM. MAPK pathway activation in pilocytic astrocytoma. Cell. Mol. Life Sci. 2012;69:1799-811.
-
(2012)
Cell. Mol. Life Sci
, vol.69
, pp. 1799-1811
-
-
Jones, D.1
Gronych, J.2
Lichter, P.3
Witt, O.4
Pfister, S.M.5
-
31
-
-
23244447037
-
Peeper DS. BRAFE600-associated senescence-like cell cycle arrest of human naevi
-
Michaloglou C, Vredeveld LCW, Soengas MS, Denoyelle C, Kuilman T, van der Horst CM M, Majoor DM, Shay JW, Mooi WJ, Peeper DS. BRAFE600-associated senescence-like cell cycle arrest of human naevi. Nature. 2005;436:720-4.
-
(2005)
Nature
, vol.436
, pp. 720-724
-
-
Michaloglou, C.1
Vredeveld, L.2
Soengas, M.S.3
Denoyelle, C.4
Kuilman, T.5
Van Der Horst, C.6
Majoor, D.M.7
Shay, J.W.8
Mooi, W.J.9
-
32
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer T, Atlas G. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 2008;455:1061-8.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
Cancer, T.1
Atlas, G.2
-
33
-
-
84886299187
-
Conditional KIAA1549:BRAF mice reveal brain region-and cell type-specific effects
-
Kaul A, Chen Y-H, Emnett RJ, Gianino SM, Gutmann DH. Conditional KIAA1549:BRAF mice reveal brain region-and cell type-specific effects. Genesis. 2013;51:708-16.
-
(2013)
Genesis
, vol.51
, pp. 708-716
-
-
Kaul, A.1
Chen, Y.-H.2
Emnett, R.J.3
Gianino, S.M.4
Gutmann, D.H.5
-
34
-
-
0035170850
-
A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family
-
Randerson-Moor J, Harland M, Williams S, Cuthbert-Heavens D, Sheridan E, Aveyard J, Sibley K, Whitaker L, Knowles M, Bishop JN, Bishop DT. A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family. Hum. Mol. Genet. 2001;10:55-62.
-
(2001)
Hum. Mol. Genet
, vol.10
, pp. 55-62
-
-
Randerson-Moor, J.1
Harland, M.2
Williams, S.3
Cuthbert-Heavens, D.4
Sheridan, E.5
Aveyard, J.6
Sibley, K.7
Whitaker, L.8
Knowles, M.9
Bishop, J.N.10
Bishop, D.T.11
-
35
-
-
84904191651
-
Factors Influencing the CNS Distribution of a Novel MEK 1/2 Inhibitor: Implications for Combination Therapy for Melanoma Brain Metastases
-
Vaidhyanathan S, Mittapalli RK, Sarkaria JN, Elmquist WF. Factors Influencing the CNS Distribution of a Novel MEK 1/2 Inhibitor: Implications for Combination Therapy for Melanoma Brain Metastases. Drug Metab. Dispos. 2014;
-
(2014)
Drug Metab. Dispos
-
-
Vaidhyanathan, S.1
Mittapalli, R.K.2
Sarkaria, J.N.3
Elmquist, W.F.4
-
36
-
-
84874442053
-
Mechanisms limiting distribution of the threonine-protein kinase B-RaF(V600E) inhibitor dabrafenib to the brain: Implications for the treatment of melanoma brain metastases
-
Mittapalli RK, Vaidhyanathan S, Dudek AZ, Elmquist WF. Mechanisms limiting distribution of the threonine-protein kinase B-RaF(V600E) inhibitor dabrafenib to the brain: implications for the treatment of melanoma brain metastases. J. Pharmacol. Exp. Ther. 2013;344:655-64.
-
(2013)
J. Pharmacol. Exp. Ther
, vol.344
, pp. 655-664
-
-
Mittapalli, R.K.1
Vaidhyanathan, S.2
Dudek, A.Z.3
Elmquist, W.F.4
-
37
-
-
56549093146
-
The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901
-
Barrett SD, Bridges AJ, Dudley DT, Saltiel AR, Fergus JH, Flamme CM, Delaney AM, Kaufman M, LePage S, Leopold WR, Przybranowski S, Sebolt-Leopold J, Van Becelaere K, et al. The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901. Bioorg. Med. Chem. Lett. Elsevier Ltd; 2008;18:6501-4.
-
(2008)
Bioorg. Med. Chem. Lett. Elsevier Ltd
, vol.18
, pp. 6501-6504
-
-
Barrett, S.D.1
Bridges, A.J.2
Dudley, D.T.3
Saltiel, A.R.4
Fergus, J.H.5
Flamme, C.M.6
Delaney, A.M.7
Kaufman, M.8
Lepage, S.9
Leopold, W.R.10
Przybranowski, S.11
Sebolt-Leopold, J.12
Van Becelaere, K.13
-
38
-
-
84861017745
-
Novel Carboxamide-Based Allosteric MEK Inhibitors: Discovery and Optimization Efforts toward XL518 (GDC-0973)
-
Rice KD, Aay N, Anand NK, Blazey CM, Bowles OJ, Bussenius J, Costanzo S, Curtis JK, Defina SC, Dubenko L, Engst S, Joshi AA, Kennedy AR, et al. Novel Carboxamide-Based Allosteric MEK Inhibitors: Discovery and Optimization Efforts toward XL518 (GDC-0973). ACS Med. Chem. Lett. 2012;3:416-21.
-
(2012)
ACS Med. Chem. Lett
, vol.3
, pp. 416-421
-
-
Rice, K.D.1
Aay, N.2
Anand, N.K.3
Blazey, C.M.4
Bowles, O.J.5
Bussenius, J.6
Costanzo, S.7
Curtis, J.K.8
Defina, S.C.9
Dubenko, L.10
Engst, S.11
Joshi, A.A.12
Kennedy, A.R.13
-
39
-
-
84859471412
-
Targeting mutant BRAF in melanoma: Current status and future development of combination therapy strategies
-
Kudchadkar R, Paraiso KHT, Smalley KSM. Targeting mutant BRAF in melanoma: current status and future development of combination therapy strategies. Cancer J. 18:124-31.
-
Cancer J
, vol.18
, pp. 124-131
-
-
Kudchadkar, R.1
Paraiso, K.2
Smalley, K.3
-
40
-
-
84949487228
-
La. Paradoxical MAPK-activation in response to treatment with tyrosine kinase inhibitors in CML: Flow cytometry loses track
-
Schnetzke U, Fischer M, Frietsch JJ, Finkensieper A, Clement JH, Hochhaus A, Rosee P La. Paradoxical MAPK-activation in response to treatment with tyrosine kinase inhibitors in CML: Flow cytometry loses track. Cytometry B. Clin. Cytom. 2013;17:601-3.
-
(2013)
Cytometry B. Clin. Cytom
, vol.17
, pp. 601-603
-
-
Schnetzke, U.1
Fischer, M.2
Frietsch, J.J.3
Finkensieper, A.4
Clement, J.H.5
Hochhaus, A.6
Rosee, P.7
-
41
-
-
84879781333
-
Selective RAF inhibitor impairs ERK1/2 phosphorylation and growth in mutant NRAS, vemurafenib-resistant melanoma cells
-
Le K, Blomain ES, Rodeck U, Aplin AE. Selective RAF inhibitor impairs ERK1/2 phosphorylation and growth in mutant NRAS, vemurafenib-resistant melanoma cells. Pigment Cell Melanoma Res. 2013;26:509-17.
-
(2013)
Pigment Cell Melanoma Res
, vol.26
, pp. 509-517
-
-
Le, K.1
Blomain, E.S.2
Rodeck, U.3
Aplin, A.E.4
|