-
1
-
-
0026548917
-
Incidence of development of factor VIII and factor IX inhibitors in haemophilias
-
Ehrenforth S, Kreuz W, Scharrer I et al. Incidence of development of factor VIII and factor IX inhibitors in haemophilias. Lancet 1992; 339: 594-598.
-
(1992)
Lancet
, vol.339
, pp. 594-598
-
-
Ehrenforth, S.1
Kreuz, W.2
Scharrer, I.3
-
2
-
-
0027473752
-
Recombinant factor VIII for the treatment of previously untreated patients with hemophilia A
-
Lusher JM, Arkin S, Abildgaard CF, Schwartz RD and the Kogenate Previously Untreated Patient Study Group. Recombinant factor VIII for the treatment of previously untreated patients with hemophilia A. N Engl J Med 1993; 328: 453-459.
-
(1993)
N Engl J Med
, vol.328
, pp. 453-459
-
-
Lusher, J.M.1
Arkin, S.2
Abildgaard, C.F.3
Schwartz, R.D.4
-
3
-
-
0028266130
-
A multicenter study of recombinant factor VIII (Recombinate): safety, efficacy and inhibitor risk in previously untreated patients with hemophilia A
-
Bray GL, Gomperts ED, Courter S et al. A multicenter study of recombinant factor VIII (Recombinate): safety, efficacy and inhibitor risk in previously untreated patients with hemophilia A. Blood 1994; 83: 2428-2435.
-
(1994)
Blood
, vol.83
, pp. 2428-2435
-
-
Bray, G.L.1
Gomperts, E.D.2
Courter, S.3
-
4
-
-
0001819208
-
Safety and immunogenicity of recombinant factor VIII (Recombinate) in previously untreated patients (PUPs): a 6.5 year update
-
June Abstract PD-663
-
Gruppo R, Bray GL, Schroth P, Perry M, Gomperts ED for the Recombinate PUP Study Group. Safety and immunogenicity of recombinant factor VIII (Recombinate) in previously untreated patients (PUPs): a 6.5 year update. Thromb Haemost 1997; 162 (June Suppl.): Abstract PD-663.
-
(1997)
Thromb Haemost
, vol.162
-
-
Gruppo, R.1
Bray, G.L.2
Schroth, P.3
Perry, M.4
Gomperts, E.D.5
-
5
-
-
0000068588
-
Recombinant FVIII (Kogenate) treatment of previously untreated patients (PUPs) with hemophilia A: update of safety, efficacy and inhibitor development after seven study years
-
June Abstract PD-664
-
Lusher JM, Arkin S, Abildgaard CF, Hurst D and the Kogenate PUP Study Group. Recombinant FVIII (Kogenate) treatment of previously untreated patients (PUPs) with hemophilia A: update of safety, efficacy and inhibitor development after seven study years. Thromb Haemost 1997; 162 (June Suppl.): Abstract PD-664.
-
(1997)
Thromb Haemost
, vol.162
-
-
Lusher, J.M.1
Arkin, S.2
Abildgaard, C.F.3
Hurst, D.4
-
6
-
-
0031773630
-
French previously untreated patients with severe hemophilia A after exposure to recombinant factor VIII: incidence of inhibitor and evaluation of immune tolerance
-
Rothschild C, Laurian Y, Satre EP et al. French previously untreated patients with severe hemophilia A after exposure to recombinant factor VIII: incidence of inhibitor and evaluation of immune tolerance. Thromb Haemost 1998; 80: 779-783.
-
(1998)
Thromb Haemost
, vol.80
, pp. 779-783
-
-
Rothschild, C.1
Laurian, Y.2
Satre, E.P.3
-
7
-
-
0001757605
-
Transient inhibitors in patients with hemophilia A
-
August,Abstract 1804
-
Brown DL, Bray GL, Scharrer I. Transient inhibitors in patients with hemophilia A. Thromb Haemost 1999 (August Suppl.); 573:Abstract 1804.
-
(1999)
Thromb Haemost
, vol.573
-
-
Brown, D.L.1
Bray, G.L.2
Scharrer, I.3
-
8
-
-
0004020482
-
Safety, efficacy and inhibitor development in previously untreated patients (PUPs) treated exclusively with B-domain deleted recombinant FVIII (BDD rFVIII)
-
Abstract 1037
-
Lusher JM, Gringeri A, Hann I, Rodriguez D. Safety, efficacy and inhibitor development in previously untreated patients (PUPs) treated exclusively with B-domain deleted recombinant FVIII (BDD rFVIII). Blood 1999; 94 (Suppl. 1): 23A (Abstract 1037).
-
(1999)
Blood
, vol.94
, pp. 23A
-
-
Lusher, J.M.1
Gringeri, A.2
Hann, I.3
Rodriguez, D.4
-
9
-
-
0000337212
-
Inhibitor formation monitoring in pediatric patients with severe hemophilia A receiving a second-generation rFVIII concentrate formulated with sucrose
-
Abstract 1050
-
Lusher JM, Kreuz W, Gazengel C et al. and the International Kogenate-FS PUP/MTP Study Group. Inhibitor formation monitoring in pediatric patients with severe hemophilia A receiving a second-generation rFVIII concentrate formulated with sucrose. Blood 1999; 94 (Suppl. 1): 237A (Abstract 1050).
-
(1999)
Blood
, vol.94
, pp. 237A
-
-
Lusher, J.M.1
Kreuz, W.2
Gazengel, C.3
-
10
-
-
0023614120
-
Etiology, natural history and management of FVIII inhibitors
-
Lusher JM. Etiology, natural history and management of FVIII inhibitors. Ann NY Acad Sci 1987; 509: 89-102.
-
(1987)
Ann NY Acad Sci
, vol.509
, pp. 89-102
-
-
Lusher, J.M.1
-
11
-
-
0032787813
-
Incidence of inhibitors in haemophilia A patients: a review of recent studies of recombinant and plasmaderived factor VIII concentrates
-
Scharrer I, Bray GL, Neutzling O. Incidence of inhibitors in haemophilia A patients: a review of recent studies of recombinant and plasmaderived factor VIII concentrates. Haemophilia 1999; 5: 145-154.
-
(1999)
Haemophilia
, vol.5
, pp. 145-154
-
-
Scharrer, I.1
Bray, G.L.2
Neutzling, O.3
-
12
-
-
0033002142
-
Review: why do inhibitors arise in patients with haemophilia A?
-
Hay CRM. Review: why do inhibitors arise in patients with haemophilia A? Br Haematol 1999; 105: 584-590.
-
(1999)
Br Haematol
, vol.105
, pp. 584-590
-
-
Hay, C.R.M.1
-
13
-
-
0030860224
-
The factor VIII mutation database on the World Wide Web: the haemophilia A mutation, search, test and resource site HAMSTeRS update (version 3.0)
-
Kemball-Cook G, Tuddenham EGD. The factor VIII mutation database on the World Wide Web: the haemophilia A mutation, search, test and resource site HAMSTeRS update (version 3.0). Nucleic Acids Res 1997; 25: 128-132.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 128-132
-
-
Kemball-Cook, G.1
Tuddenham, E.G.D.2
-
14
-
-
0031856834
-
The genetic basis of inhibitor development in haemophilia A
-
Tuddenham EGD, McVey JH. The genetic basis of inhibitor development in haemophilia A. Haemophilia 1998; 4: 543-545.
-
(1998)
Haemophilia
, vol.4
, pp. 543-545
-
-
Tuddenham, E.G.D.1
McVey, J.H.2
-
15
-
-
0029617930
-
Haemophilia A: mutation type determines risk of inhibitor formation
-
Schwaab R, Brackmann HH, Meyer C et al. Haemophilia A: mutation type determines risk of inhibitor formation. Thromb Haemost 1995; 74: 1402-1406.
-
(1995)
Thromb Haemost
, vol.74
, pp. 1402-1406
-
-
Schwaab, R.1
Brackmann, H.H.2
Meyer, C.3
-
16
-
-
0029552960
-
Factor IX: molecular structure, epitopes and mutations associated with inhibitor formation
-
Aledort LM, Hoyer LW, Lusher JM, Reisner HM, White GC, eds, New York: Plenum Press
-
High KA. Factor IX: molecular structure, epitopes and mutations associated with inhibitor formation. In: Aledort LM, Hoyer LW, Lusher JM, Reisner HM, White GC, eds. Inhibitors to Coagulation Factors. New York: Plenum Press, 1995: 79-86.
-
(1995)
Inhibitors to Coagulation Factors
, pp. 79-86
-
-
High, K.A.1
-
17
-
-
0029087058
-
Gene mutations and inhibitor formation in patients with hemophilia B
-
Ljung RCR. Gene mutations and inhibitor formation in patients with hemophilia B. Acta Haematol 1995; 94 (Suppl. 1): 49-52.
-
(1995)
Acta Haematol
, vol.94
, pp. 49-52
-
-
Ljung, R.C.R.1
-
19
-
-
0029926277
-
Haemophilia B (6th edn): a data base of point mutations and short additions and deletions
-
Giannelli F, Green PM, Sommer SS et al. Haemophilia B (6th edn): a data base of point mutations and short additions and deletions. Nucleic Acids Res 1996: 24; 103-118.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 103-118
-
-
Giannelli, F.1
Green, P.M.2
Sommer, S.S.3
-
20
-
-
84949445985
-
Unique aspects of inhibitors in patients with hemophilia B
-
Shapiro A, ed., National Hemophilia Foundation: New York
-
Shapiro AD. Unique aspects of inhibitors in patients with hemophilia B. In: Shapiro A, ed. Inhibitors in Hemophilia: Current Perspectives and Future Directions. National Hemophilia Foundation: New York, 2001: 7-15.
-
(2001)
Inhibitors in Hemophilia: Current Perspectives and Future Directions
, pp. 7-15
-
-
Shapiro, A.D.1
-
22
-
-
6644227418
-
The Malmö International Brother Study (MIBS): further support for genetic predisposition to inhibitor development
-
Astermark J, Berntorp E, White GC, Kroner BL and the MIBS Study Group. The Malmö International Brother Study (MIBS): further support for genetic predisposition to inhibitor development. Haemophilia 2001; 7: 267-272.
-
(2001)
Haemophilia
, vol.7
, pp. 267-272
-
-
Astermark, J.1
Berntorp, E.2
White, G.C.3
Kroner, B.L.4
-
23
-
-
84949452602
-
The role of genetics in the development of factor VIII inhibitors
-
Shapiro A, ed., National Hemophilia Foundation:New York
-
Gill GM. The role of genetics in the development of factor VIII inhibitors. In: Shapiro A, ed. Inhibitors in Hemophilia: Current Perspectives and Future Directions. National Hemophilia Foundation:New York, 2001: 31-42.
-
(2001)
Inhibitors in Hemophilia: Current Perspectives and Future Directions
, pp. 31-42
-
-
Gill, G.M.1
-
24
-
-
0021308824
-
The natural history of factor VIII inhibitors in patients with hemophilia A
-
Gill GM. The natural history of factor VIII inhibitors in patients with hemophilia A. Prog Clin Biol Res 1984; 150: 19-29.
-
(1984)
Prog Clin Biol Res
, vol.150
, pp. 19-29
-
-
Gill, G.M.1
-
25
-
-
0000939750
-
Increased frequency of inhibitors in African American hemophilia A patients
-
Addiego JE, Kasper C, Abildgaard C et al. Increased frequency of inhibitors in African American hemophilia A patients. Blood 1994; 84 (Suppl. 1): 239 [Abstract].
-
(1994)
Blood
, vol.84
, pp. 239
-
-
Addiego, J.E.1
Kasper, C.2
Abildgaard, C.3
-
26
-
-
84949427737
-
Epitope specificity of anti-factor VIII antibodies
-
Shapiro A, ed., National Hemophilia Foundation: New York
-
Scandella D. Epitope specificity of anti-factor VIII antibodies. In:Shapiro A, ed. Inhibitors in Hemophilia: Current Perspectives and Future Directions. National Hemophilia Foundation: New York, 2001: 17-29.
-
(2001)
Inhibitors in Hemophilia: Current Perspectives and Future Directions
, pp. 17-29
-
-
Scandella, D.1
-
27
-
-
0032973849
-
Utilization of previously treated patients (PTPs), noninfected patients (NIPs), and previously untreated patients (PUPs) in the evaluation of new factor VIII and factor IX concentrates: recommendation of the Scientific Subcommittee on factor VIII and factor IX of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis
-
White GC, DiMichele D, Mertens K et al. Utilization of previously treated patients (PTPs), noninfected patients (NIPs), and previously untreated patients (PUPs) in the evaluation of new factor VIII and factor IX concentrates: recommendation of the Scientific Subcommittee on factor VIII and factor IX of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Thromb Haemost 1999; 81: 462.
-
(1999)
Thromb Haemost
, vol.81
, pp. 462
-
-
White, G.C.1
DiMichele, D.2
Mertens, K.3
-
28
-
-
1642312467
-
Safety and efficacy in previously untreated patients (PUPs) treated exclusively with B-domain deleted factor VIII (BDD rFVIII)
-
Congress, Abstract
-
Lusher JM, Shapiro A, Gruppo R, Bedrosian CL, Nguyen K and the ReFacto PUP Study Group. Safety and efficacy in previously untreated patients (PUPs) treated exclusively with B-domain deleted factor VIII (BDD rFVIII). Thromb Haemost 2001; Congress Suppl.: 2558 [Abstract].
-
(2001)
Thromb Haemost
, pp. 2558
-
-
Lusher, J.M.1
Shapiro, A.2
Gruppo, R.3
Bedrosian, C.L.4
Nguyen, K.5
-
29
-
-
79955114793
-
Recombinant FVIII formulated with sucrose (rFVIII-FS) is safe and efficacious in pediatric patients with hemophilia A.
-
Abstract
-
Kreuz W, Manco-Johnson M, Gazengel C et al. Recombinant FVIII formulated with sucrose (rFVIII-FS) is safe and efficacious in pediatric patients with hemophilia A. Blood 2000; 96: 226A [Abstract].
-
(2000)
Blood
, vol.96
, pp. 226A
-
-
Kreuz, W.1
Manco-Johnson, M.2
Gazengel, C.3
-
30
-
-
84949470915
-
Anti-FVIII inhibitor incidence in previously untreated patients (PUPs) with hemophilia exposed to Kogenate (German-Italian PUP Study on Inhibitors)
-
Congress June :Abstract PS-2642
-
Gringeri A, Kreuz W, Escuriola-Ettinghausen C et al. Anti-FVIII inhibitor incidence in previously untreated patients (PUPs) with hemophilia exposed to Kogenate (German-Italian PUP Study on Inhibitors). Thromb Haemost 1997; 648 (Congress Suppl. June):Abstract PS-2642.
-
(1997)
Thromb Haemost
, vol.648
-
-
Gringeri, A.1
Kreuz, W.2
Escuriola-Ettinghausen, C.3
-
32
-
-
0028837315
-
The Nijmegen modification of the Bethesda assay for factor VIII inhibitors: improved specificity and reliability.
-
Verbruggen B, Novakova I, Wessels H et al. The Nijmegen modification of the Bethesda assay for factor VIII inhibitors: improved specificity and reliability. Thromb Haemost 1995; 73: 247-251.
-
(1995)
Thromb Haemost
, vol.73
, pp. 247-251
-
-
Verbruggen, B.1
Novakova, I.2
Wessels, H.3
-
33
-
-
0035159198
-
Structural and functional characteristics of the B-domain deleted recombinant proteins, r-VIII SQ
-
Sandberg H, Almstedt A, Brandt J et al. Structural and functional characteristics of the B-domain deleted recombinant proteins, r-VIII SQ. Thromb Haemost 2001; 85: 93-100.
-
(2001)
Thromb Haemost
, vol.85
, pp. 93-100
-
-
Sandberg, H.1
Almstedt, A.2
Brandt, J.3
-
34
-
-
0030855794
-
Second generation, B-domain deleted recombinant factor VIII
-
Berntorp E. Second generation, B-domain deleted recombinant factor VIII. Thromb Haemost 1996; 78: 256-260.
-
(1996)
Thromb Haemost
, vol.78
, pp. 256-260
-
-
Berntorp, E.1
-
36
-
-
84949440833
-
Eighteen months experience with a sucrose-formulated full-length rFVIII (rVIII-SF) in previously untreated patients (PUPs) and minimally treated patients (MTPs) with severe hemophilia A.
-
Abstract
-
Kreuz W, Gazengel C, Gorina E, Kellermann E and the European PUP/MTP Study Group. Eighteen months experience with a sucrose-formulated full-length rFVIII (rVIII-SF) in previously untreated patients (PUPs) and minimally treated patients (MTPs) with severe hemophilia A. Ann Hematol 2001; 80: A37 [Abstract].
-
(2001)
Ann Hematol
, vol.80
, pp. A37
-
-
Kreuz, W.1
Gazengel, C.2
Gorina, E.3
Kellermann, E.4
-
37
-
-
0028230028
-
Summary of clinical experience with recombinant factor VIII products: Kogenate
-
Lusher JM. Summary of clinical experience with recombinant factor VIII products: Kogenate. Ann Hematol 1994; 68: 53-56.
-
(1994)
Ann Hematol
, vol.68
, pp. 53-56
-
-
Lusher, J.M.1
-
38
-
-
0026622961
-
Prevalence of inhibitors in a population of 3435 hemophilia patients in France
-
Sultan Y and the French Hemophilia Study Group. Prevalence of inhibitors in a population of 3435 hemophilia patients in France. Thromb Haemost 1992; 67: 600-602.
-
(1992)
Thromb Haemost
, vol.67
, pp. 600-602
-
-
Sultan, Y.1
-
39
-
-
0030062131
-
Prevalence of factor IX inhibitors among patients with haemophilia B: results of a large-scale North American survey
-
Katz J. Prevalence of factor IX inhibitors among patients with haemophilia B: results of a large-scale North American survey. Haemophilia 1996; 2: 28-31.
-
(1996)
Haemophilia
, vol.2
, pp. 28-31
-
-
Katz, J.1
-
40
-
-
0031785486
-
Occurrence of hemophilia in the United States. The Hemophilia Surveillance System Project Investigators
-
Soucie JM, Evatt B, Jackson D. Occurrence of hemophilia in the United States. The Hemophilia Surveillance System Project Investigators. Am J Hematol 1998; 59: 288-294.
-
(1998)
Am J Hematol
, vol.59
, pp. 288-294
-
-
Soucie, J.M.1
Evatt, B.2
Jackson, D.3
-
42
-
-
6544277992
-
Anaphylactic response to factor IX replacement therapy in haemophilia B patients: complete gene deletions confer the highest risk
-
Thorland EC, Drost JB, Lusher JM et al. Anaphylactic response to factor IX replacement therapy in haemophilia B patients: complete gene deletions confer the highest risk. Haemophilia 1999; 5: 101-105.
-
(1999)
Haemophilia
, vol.5
, pp. 101-105
-
-
Thorland, E.C.1
Drost, J.B.2
Lusher, J.M.3
-
43
-
-
0033935277
-
Inhibitor antibodies to factor VIII and factor IX: management
-
Lusher JM. Inhibitor antibodies to factor VIII and factor IX: management. Semin Thromb Haemost 2000; 26: 179-188.
-
(2000)
Semin Thromb Haemost
, vol.26
, pp. 179-188
-
-
Lusher, J.M.1
|