Genetic ablation of extra domain a of fibronectin in hypercholesterolemic mice improves stroke outcome by reducing thrombo-inflammation

Circulation

Volumn 132, Issue 23, 2015, Pages 2237-2247

  Dhanesha, Nirav ^a   Ahmad, Ajmal ^a   Prakash, Prem ^a   Doddapattar, Prakash ^a   Lentz, Steven R ^a   Chauhan, Anil K ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

fibronectins; hypercholesterolemia; inflammation; stroke; thrombosis

Indexed keywords

APOLIPOPROTEIN E; FIBRONECTIN; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; INTERLEUKIN 1BETA; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; EXTRA DOMAIN A FIBRONECTIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW TRANSPLANTATION; BRAIN INFARCTION SIZE; BRAIN INJURY; BRAIN ISCHEMIA; CAROTID ARTERY THROMBOSIS; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DISEASE EXACERBATION; GENE TARGETING; HYPERCHOLESTEROLEMIA; INFLAMMATION; MALE; MOUSE; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; ANIMAL; C57BL MOUSE; DEFICIENCY; DISEASE MODEL; FEMALE; GENE DELETION; GENETICS; KNOCKOUT MOUSE; PATHOLOGY; STROKE; TREATMENT OUTCOME;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; FIBRONECTINS; GENE DELETION; HYPERCHOLESTEROLEMIA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; STROKE; TREATMENT OUTCOME;

EID: 84949443463     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.115.016540     Document Type: Article

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