High Salt Intake Increases Blood Pressure via BDNF-Mediated Downregulation of KCC2 and Impaired Baroreflex Inhibition of Vasopressin Neurons

Neuron

Volumn 85, Issue 3, 2015, Pages 549-560

  Choe, Katrina Y ^a   Han, Su Y ^b   Gaub, Perrine ^c   Shell, Brent ^d   Voisin, Daniel L ^e   Knapp, Blayne A ^d   Barker, Philip A ^c   Brown, Colin H ^b   Cunningham, J Thomas ^d   Bourque, Charles W ^a  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c MCGILL UNIVERSITY   (Canada)

^d UNIVERSITY OF NORTH TEXAS   (United States)

^e INSTITUT FRANÇOIS MAGENDIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; POTASSIUM CHLORIDE COTRANSPORTER 2; VASOPRESSIN; COTRANSPORTER; POTASSIUM-CHLORIDE SYMPORTERS; SALT INTAKE; VASOPRESSIN DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DOWN REGULATION; HYPERTENSION; MALE; MICROGLIA; NERVE CELL PLASTICITY; NERVE CONDUCTION; NONHUMAN; PRESSORECEPTOR REFLEX; PROTEIN FUNCTION; RAT; SALT INTAKE; ADVERSE EFFECTS; ANIMAL; BLOOD PRESSURE; CHEMICALLY INDUCED; DRUG EFFECTS; LONG EVANS RAT; METABOLISM; NERVE CELL; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY;

ANIMALS; BAROREFLEX; BLOOD PRESSURE; BRAIN-DERIVED NEUROTROPHIC FACTOR; DOWN-REGULATION; HYPERTENSION; MALE; NEURONS; ORGAN CULTURE TECHNIQUES; RATS; RATS, LONG-EVANS; SODIUM CHLORIDE, DIETARY; SYMPORTERS; VASOPRESSINS;

EID: 84949324436     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2014.12.048     Document Type: Article

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