-
1
-
-
77957764473
-
Vascular endothelial growth factor and age-related macular degeneration: from basic science to therapy
-
Ferrara N. Vascular endothelial growth factor and age-related macular degeneration: from basic science to therapy. Nat. Med. 2010, 16:1107-1111.
-
(2010)
Nat. Med.
, vol.16
, pp. 1107-1111
-
-
Ferrara, N.1
-
2
-
-
0037277741
-
Vascular endothelial growth factors and angiogenesis in eye disease
-
Witmer A.N., Vrensen G., Van Noorden C.J.F., Schlingemann R.O. Vascular endothelial growth factors and angiogenesis in eye disease. Prog. Retin Eye Res. 2003, 22:1-29.
-
(2003)
Prog. Retin Eye Res.
, vol.22
, pp. 1-29
-
-
Witmer, A.N.1
Vrensen, G.2
Van Noorden, C.J.F.3
Schlingemann, R.O.4
-
3
-
-
0020572581
-
Angiogenesis inhibition and tumor-regression caused by heparin or a heparin fragment in the presence of cortisone
-
Folkman J., Langer R., Linhardt R.J., Haudenschild C., Taylor S. Angiogenesis inhibition and tumor-regression caused by heparin or a heparin fragment in the presence of cortisone. Science 1983, 221:719-725.
-
(1983)
Science
, vol.221
, pp. 719-725
-
-
Folkman, J.1
Langer, R.2
Linhardt, R.J.3
Haudenschild, C.4
Taylor, S.5
-
4
-
-
85013312416
-
Tumor angiogenesis - therapeutic implications
-
Folkman J., Bach M., Rowe J.W., Davidoff F., Lambert P., Hirsch C., et al. Tumor angiogenesis - therapeutic implications. N. Engl. J. Med. 1971, 285:1182-1186.
-
(1971)
N. Engl. J. Med.
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
Bach, M.2
Rowe, J.W.3
Davidoff, F.4
Lambert, P.5
Hirsch, C.6
-
5
-
-
38449100932
-
Anti-vascular endothelial growth factor therapy for ocular neovascular disease
-
Andreoli C.M., Miller J.W. Anti-vascular endothelial growth factor therapy for ocular neovascular disease. Curr. Opin. Ophthalmol. 2007, 18:502-508.
-
(2007)
Curr. Opin. Ophthalmol.
, vol.18
, pp. 502-508
-
-
Andreoli, C.M.1
Miller, J.W.2
-
6
-
-
33645095226
-
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease
-
Ng E.W., Shima D.T., Calias P., Cunningham E.T., Guyer D.R., Adamis A.P. Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease. Nat. Rev. Drug Discov. 2006, 5:123-132.
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 123-132
-
-
Ng, E.W.1
Shima, D.T.2
Calias, P.3
Cunningham, E.T.4
Guyer, D.R.5
Adamis, A.P.6
-
7
-
-
27944490875
-
VEGF as a therapeutic target in cancer
-
Ferrara N. VEGF as a therapeutic target in cancer. Oncology 2005, 69:11-16.
-
(2005)
Oncology
, vol.69
, pp. 11-16
-
-
Ferrara, N.1
-
8
-
-
0037098860
-
VEGF(165)b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma
-
Bates D.O., Cui T.G., Doughty J.M., Winkler M., Sugiono M., Shields J.D., et al. VEGF(165)b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma. Cancer Res. 2002, 62:4123-4131.
-
(2002)
Cancer Res.
, vol.62
, pp. 4123-4131
-
-
Bates, D.O.1
Cui, T.G.2
Doughty, J.M.3
Winkler, M.4
Sugiono, M.5
Shields, J.D.6
-
9
-
-
56349136033
-
Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors
-
Nowak D.G., Woolard J., Amin E.M., Konopatskaya O., Saleem M.A., Churchill A.J., et al. Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors. J. Cell Sci. 2008, 121:3487-3495.
-
(2008)
J. Cell Sci.
, vol.121
, pp. 3487-3495
-
-
Nowak, D.G.1
Woolard, J.2
Amin, E.M.3
Konopatskaya, O.4
Saleem, M.A.5
Churchill, A.J.6
-
10
-
-
7444240909
-
VEGF(165)b, an inhibitory vascular endothelial growth factor splice variant: Mechanism of action, in vivo effect on angiogenesis and endogenous protein expression
-
Woolard J., Wang W.Y., Bevan H.S., Qiu Y., Morbidelli L., Pritchard-Jones R.O., et al. VEGF(165)b, an inhibitory vascular endothelial growth factor splice variant: Mechanism of action, in vivo effect on angiogenesis and endogenous protein expression. Cancer Res. 2004, 64:7822-7835.
-
(2004)
Cancer Res.
, vol.64
, pp. 7822-7835
-
-
Woolard, J.1
Wang, W.Y.2
Bevan, H.S.3
Qiu, Y.4
Morbidelli, L.5
Pritchard-Jones, R.O.6
-
11
-
-
77955866848
-
VEGF-A165b Is cytoprotective and Antiangiogenic in the Retina
-
Magnussen A.L., Rennel E.S., Hua J., Bevan H.S., Long N.B., Lehrling C., et al. VEGF-A165b Is cytoprotective and Antiangiogenic in the Retina. Investig. Ophthalmol. Vis. Sci. 2010, 51:4273-4281.
-
(2010)
Investig. Ophthalmol. Vis. Sci.
, vol.51
, pp. 4273-4281
-
-
Magnussen, A.L.1
Rennel, E.S.2
Hua, J.3
Bevan, H.S.4
Long, N.B.5
Lehrling, C.6
-
12
-
-
27744448867
-
Prospective incidence study of diabetes mellitus in New Zealand children aged 0 to 14 years. Diabetologia 48: 643-648
-
on behalf of the New Zealand Children's Diabetes Working Group
-
Willis J., Scott R., Darlow B., Campbell-Stokes P.L., Taylor B.J. Prospective incidence study of diabetes mellitus in New Zealand children aged 0 to 14 years. Diabetologia 48: 643-648. Diabetologia 2005, 2005(48):2442-2443. on behalf of the New Zealand Children's Diabetes Working Group.
-
(2005)
Diabetologia
, vol.2005
, Issue.48
, pp. 2442-2443
-
-
Willis, J.1
Scott, R.2
Darlow, B.3
Campbell-Stokes, P.L.4
Taylor, B.J.5
-
13
-
-
42149152015
-
VEGF165b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro-and antiangiogenic VEGF-A isoforms has implications for therapy
-
Varey A., Rennel E., Qiu Y., Bevan H., Perrin R., Raffy S., et al. VEGF165b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro-and antiangiogenic VEGF-A isoforms has implications for therapy. Br. J. cancer 2008, 98:1366-1379.
-
(2008)
Br. J. cancer
, vol.98
, pp. 1366-1379
-
-
Varey, A.1
Rennel, E.2
Qiu, Y.3
Bevan, H.4
Perrin, R.5
Raffy, S.6
-
14
-
-
33644977975
-
VEGF(165)-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase
-
Robinson C.J., Mulloy B., Gallagher J.T., Stringer S.E. VEGF(165)-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase. J. Biol. Chem. 2006, 281:1731-1740.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 1731-1740
-
-
Robinson, C.J.1
Mulloy, B.2
Gallagher, J.T.3
Stringer, S.E.4
-
15
-
-
54549123309
-
VEGF-A splicing: the key to anti-angiogenic therapeutics?
-
Harper S.J., Bates D.O. VEGF-A splicing: the key to anti-angiogenic therapeutics?. Nat. Rev. Cancer 2008, 8:880-887.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 880-887
-
-
Harper, S.J.1
Bates, D.O.2
-
16
-
-
75349091269
-
Structure-function analysis of VEGF receptor activation and the role of coreceptors in angiogenic signaling
-
Grunewald F.S., Prota A.E., Giese A., Ballmer-Hofer K. Structure-function analysis of VEGF receptor activation and the role of coreceptors in angiogenic signaling. BBA Proteins Proteom. 2010, 1804:567-580.
-
(2010)
BBA Proteins Proteom.
, vol.1804
, pp. 567-580
-
-
Grunewald, F.S.1
Prota, A.E.2
Giese, A.3
Ballmer-Hofer, K.4
-
17
-
-
84874772582
-
The role of drosophila heparan sulfate 6-O-endosulfatase in sulfation compensation
-
Dejima K., Kleinschmit A., Takemura M., Choi P.Y., Kinoshita-Toyoda A., Toyoda H., et al. The role of drosophila heparan sulfate 6-O-endosulfatase in sulfation compensation. J. Biol. Chem. 2013, 288:6574-6582.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 6574-6582
-
-
Dejima, K.1
Kleinschmit, A.2
Takemura, M.3
Choi, P.Y.4
Kinoshita-Toyoda, A.5
Toyoda, H.6
-
18
-
-
77955866848
-
VEGF-A165b is cytoprotective and antiangiogenic in the retina
-
Magnussen A.L., Rennel E.S., Hua J., Bevan H.S., Long N.B., Lehrling C., et al. VEGF-A165b is cytoprotective and antiangiogenic in the retina. Investig. Ophthalmol. Vis. Sci. 2010, 51:4273-4281.
-
(2010)
Investig. Ophthalmol. Vis. Sci.
, vol.51
, pp. 4273-4281
-
-
Magnussen, A.L.1
Rennel, E.S.2
Hua, J.3
Bevan, H.S.4
Long, N.B.5
Lehrling, C.6
-
19
-
-
79958816088
-
Targeting hyaluronidase for cancer therapy: Antitumor activity of sulfated hyaluronic acid in prostate cancer cells
-
Benitez A., Yates T.J., Lopez L.E., Cerwinka W.H., Bakkar A., Lokeshwar V.B. Targeting hyaluronidase for cancer therapy: Antitumor activity of sulfated hyaluronic acid in prostate cancer cells. Cancer Res. 2011, 71:4085-4095.
-
(2011)
Cancer Res.
, vol.71
, pp. 4085-4095
-
-
Benitez, A.1
Yates, T.J.2
Lopez, L.E.3
Cerwinka, W.H.4
Bakkar, A.5
Lokeshwar, V.B.6
-
20
-
-
77955347373
-
Synthetic heparan sulfate oligosaccharides inhibit endothelial cell functions essential for angiogenesis
-
Cole C.L., Hansen S.U., Barath M., Rushton G., Gardiner J.M., Avizienyte E., et al. Synthetic heparan sulfate oligosaccharides inhibit endothelial cell functions essential for angiogenesis. PLoS One 2010, 5.
-
(2010)
PLoS One
, vol.5
-
-
Cole, C.L.1
Hansen, S.U.2
Barath, M.3
Rushton, G.4
Gardiner, J.M.5
Avizienyte, E.6
-
21
-
-
21744450786
-
Heparan sulphate proteoglycans: the sweet side of development
-
Hacker U., Nybakken K., Perrimon N. Heparan sulphate proteoglycans: the sweet side of development. Nat. Rev. Mol. Cell Biol. 2005, 6:530-541.
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 530-541
-
-
Hacker, U.1
Nybakken, K.2
Perrimon, N.3
-
22
-
-
72449141752
-
Modifications of hyaluronan influence the interaction with human bone morphogenetic protein-4 (hBMP-4)
-
Hintze V., Moeller S., Schnabelrauch M., Bierbaum S., Viola M., Worch H., et al. Modifications of hyaluronan influence the interaction with human bone morphogenetic protein-4 (hBMP-4). Biomacromolecules 2009, 10:3290-3297.
-
(2009)
Biomacromolecules
, vol.10
, pp. 3290-3297
-
-
Hintze, V.1
Moeller, S.2
Schnabelrauch, M.3
Bierbaum, S.4
Viola, M.5
Worch, H.6
-
23
-
-
0028228672
-
Synthetic polysulfated hyaluronic acid is a potent inhibitor for tumor necrosis factor production
-
Chang N.S., Intrieri C., Mattison J., Armand G. Synthetic polysulfated hyaluronic acid is a potent inhibitor for tumor necrosis factor production. J. Leukoc. Biol. 1994, 55:778-784.
-
(1994)
J. Leukoc. Biol.
, vol.55
, pp. 778-784
-
-
Chang, N.S.1
Intrieri, C.2
Mattison, J.3
Armand, G.4
-
24
-
-
0001385243
-
Hyaluronidase induces murine L929 fibrosarcoma cells resistant to tumor necrosis factor and fas cytotoxicity in the presence of actinomycin D
-
Chang N.-S. Hyaluronidase induces murine L929 fibrosarcoma cells resistant to tumor necrosis factor and fas cytotoxicity in the presence of actinomycin D. Cell Biochem. Biophys. 1995, 27:109-132.
-
(1995)
Cell Biochem. Biophys.
, vol.27
, pp. 109-132
-
-
Chang, N.-S.1
-
25
-
-
0032118794
-
Sulphated hyaluronic acids: a chemical and biological characterisation
-
Magnani A., Lamponi S., Rappuoli R., Barbucci R. Sulphated hyaluronic acids: a chemical and biological characterisation. Polym. Int. 1998, 46:225-240.
-
(1998)
Polym. Int.
, vol.46
, pp. 225-240
-
-
Magnani, A.1
Lamponi, S.2
Rappuoli, R.3
Barbucci, R.4
-
27
-
-
33644804663
-
Discovery of a sulfated tetrapeptide that binds to vascular endothelial growth factor
-
Maynard H.D., Hubbell J.A. Discovery of a sulfated tetrapeptide that binds to vascular endothelial growth factor. Acta Biomater. 2005, 1:451-459.
-
(2005)
Acta Biomater.
, vol.1
, pp. 451-459
-
-
Maynard, H.D.1
Hubbell, J.A.2
-
28
-
-
84866522723
-
Control of protein-binding kinetics on synthetic polymer nanoparticles by tuning flexibility and inducing conformation changes of polymer chains
-
Hoshino Y., Nakamoto M., Miura Y. Control of protein-binding kinetics on synthetic polymer nanoparticles by tuning flexibility and inducing conformation changes of polymer chains. J. Am. Chem. Soc. 2012, 134:15209-15212.
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 15209-15212
-
-
Hoshino, Y.1
Nakamoto, M.2
Miura, Y.3
-
29
-
-
78149441693
-
Regulation of pathologic retinal angiogenesis in mice and inhibition of VEGF-VEGFR2 binding by soluble heparan sulfate
-
Nishiguchi K.M., Kataoka K., Kachi S., Komeima K., Terasaki H. Regulation of pathologic retinal angiogenesis in mice and inhibition of VEGF-VEGFR2 binding by soluble heparan sulfate. PLoS One 2010, 5:e13493.
-
(2010)
PLoS One
, vol.5
, pp. e13493
-
-
Nishiguchi, K.M.1
Kataoka, K.2
Kachi, S.3
Komeima, K.4
Terasaki, H.5
-
30
-
-
0032530717
-
VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 Å resolution and mutational analysis of the interface
-
Muller Y.A., Chen Y., Christinger H.W., Li B., Cunningham B.C., Lowman H.B., et al. VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 Å resolution and mutational analysis of the interface. Structure 1998, 6:1153-1167.
-
(1998)
Structure
, vol.6
, pp. 1153-1167
-
-
Muller, Y.A.1
Chen, Y.2
Christinger, H.W.3
Li, B.4
Cunningham, B.C.5
Lowman, H.B.6
-
31
-
-
30044436689
-
A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF165
-
Lee J.-H., Canny M.D., De Erkenez A., Krilleke D., Ng Y.-S., Shima D.T., et al. A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF165. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:18902-18907.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 18902-18907
-
-
Lee, J.-H.1
Canny, M.D.2
De Erkenez, A.3
Krilleke, D.4
Ng, Y.-S.5
Shima, D.T.6
-
32
-
-
0030801996
-
Expression of basic fibroblast growth factor (FGF-2)-associated with tumour proliferation in human pancreatic carcinoma
-
Yamazaki K., Nagao T., Yamaguchi T., Saisho H., Kondo Y. Expression of basic fibroblast growth factor (FGF-2)-associated with tumour proliferation in human pancreatic carcinoma. Virchows Arch. 1997, 431:95-101.
-
(1997)
Virchows Arch.
, vol.431
, pp. 95-101
-
-
Yamazaki, K.1
Nagao, T.2
Yamaguchi, T.3
Saisho, H.4
Kondo, Y.5
-
33
-
-
53449095951
-
Comparison of bevacizumab, ranibizumab, and pegaptanib in vitro: efficiency and possible additional pathways
-
Klettner A., Roider J. Comparison of bevacizumab, ranibizumab, and pegaptanib in vitro: efficiency and possible additional pathways. Investiga. Ophthalmol. Vis. Sci. 2008, 49:4523.
-
(2008)
Investiga. Ophthalmol. Vis. Sci.
, vol.49
, pp. 4523
-
-
Klettner, A.1
Roider, J.2
-
34
-
-
78149441693
-
Regulation of pathologic retinal angiogenesis in mice and inhibition of VEGF-VEGFR2 binding by soluble heparan sulfate
-
Nishiguchi K.M., Kataoka K., Kachi S., Komeima K., Terasaki H. Regulation of pathologic retinal angiogenesis in mice and inhibition of VEGF-VEGFR2 binding by soluble heparan sulfate. PLoS One 2010, 5.
-
(2010)
PLoS One
, vol.5
-
-
Nishiguchi, K.M.1
Kataoka, K.2
Kachi, S.3
Komeima, K.4
Terasaki, H.5
-
35
-
-
0031046646
-
Growth factors in the extracellular matrix
-
Taipale J., Keski-Oja J. Growth factors in the extracellular matrix. FASEB J. 1997, 11:51-59.
-
(1997)
FASEB J.
, vol.11
, pp. 51-59
-
-
Taipale, J.1
Keski-Oja, J.2
-
36
-
-
20544455330
-
Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy
-
Ferrara N., Hillan K.J., Novotny W. Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy. Biochem. biophys. Res. Commun. 2005, 333:328-335.
-
(2005)
Biochem. biophys. Res. Commun.
, vol.333
, pp. 328-335
-
-
Ferrara, N.1
Hillan, K.J.2
Novotny, W.3
|