TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors

Nature Genetics

Volumn 47, Issue 12, 2015, Pages 1411-1414

  Valentijn, Linda J ^a   Koster, Jan ^a   Zwijnenburg, Danny A ^a   Hasselt, Nancy E ^a   Van Sluis, Peter ^a   Volckmann, Richard ^a   Van Noesel, Max M ^b   George, Rani E ^c,d   Tytgat, Godelieve A M ^a,b   Molenaar, Jan J ^a   Versteeg, Rogier ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b Department of Radiation Oncology   (Netherlands)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATRX PROTEIN; CYCLIN DEPENDENT KINASE 4; HISTONE H3; MYCN PROTEIN; PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG; ATRX PROTEIN, HUMAN; DNA HELICASE; MYCN PROTEIN, HUMAN; NUCLEAR PROTEIN; ONCOPROTEIN; TELOMERASE; TERT PROTEIN, HUMAN;

ARTICLE; CANCER PROGNOSIS; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME 2; CHROMOSOME 5; COMPARATIVE GENOMIC HYBRIDIZATION; ENHANCER REGION; GENE AMPLIFICATION; GENE DELETION; GENE OVEREXPRESSION; GENE REARRANGEMENT; HISTONE ACETYLATION; HUMAN; NEUROBLASTOMA; PRIORITY JOURNAL; PROMOTER REGION; QUANTITATIVE ANALYSIS; RESTRICTION FRAGMENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING; SUPER ENHANCER; TELOMERE HOMEOSTASIS; TELOMERE RESTRICTION FRAGMENT; TRANSCRIPTION INITIATION; GENE EXPRESSION REGULATION; GENETICS; HIGH THROUGHPUT SEQUENCING; HUMAN GENOME; PATHOLOGY; PROCEDURES; TELOMERE;

DNA HELICASES; GENE AMPLIFICATION; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REARRANGEMENT; GENOME, HUMAN; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; NEUROBLASTOMA; NUCLEAR PROTEINS; ONCOGENE PROTEINS; TELOMERASE; TELOMERE;

EID: 84949095445     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3438     Document Type: Article

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