Decreased expression of dual specificity phosphatase 22 in colorectal cancer and its potential prognostic relevance for stage IV CRC patients

Tumor Biology

Volumn 36, Issue 11, 2015, Pages 8531-8535

  Yu, Dan ^a,b   Li, Zhenli ^a,b   Gan, Meifu ^c   Zhang, Hanyun ^d   Yin, Xiaoyang ^a   Tang, Shunli ^a   Wan, Ledong ^a,b   Tian, Yiping ^a,b   Zhang, Shuai ^a,b   Zhu, Yimin ^e   Lai, Maode ^a,b   Zhang, Dandan ^a,b  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Key Laboratory of Neuroscience   (China)

^c TAIZHOU HOSPITAL OF ZHEJIANG PROVINCE   (China)

^d THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^e ZHEJIANG UNIVERSITY   (China)

Author keywords

Colorectal cancer; Dual specificity phosphatase 22; Prognosis; Progression

Indexed keywords

DUAL SPECIFICITY PHOSPHATASE; DUAL SPECIFICITY PHOSPHATASE 22; UNCLASSIFIED DRUG; DUSP22 PROTEIN, HUMAN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE; TUMOR MARKER;

ADULT; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; COLORECTAL CANCER; DUSP22 GENE; FEMALE; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE IDENTIFICATION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; SURVIVAL RATE; TUMOR INVASION; TUMOR VOLUME; AGED; BIOSYNTHESIS; COLORECTAL TUMOR; GENE EXPRESSION REGULATION; GENETICS; KAPLAN MEIER METHOD; LYMPH NODE METASTASIS; MIDDLE AGED; PATHOLOGY; PROGNOSIS;

ADULT; AGED; BIOMARKERS, TUMOR; COLORECTAL NEOPLASMS; DUAL-SPECIFICITY PHOSPHATASES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KAPLAN-MEIER ESTIMATE; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASE PHOSPHATASES; NEOPLASM STAGING; PROGNOSIS; RNA, MESSENGER;

EID: 84949090251     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-3588-7     Document Type: Article

References (21)

1. Siegel R, DeSantis C, Jemal A. Colorectal cancer statistics, 2014. CA Cancer J Clin. 2014;64(2):104–17. doi:10.3322/Caac.21220.
2. Siegel R, Ma JM, Zou ZH, Jemal A. Cancer statistics, 2014. CA Cancer J Clin. 2014;64(1):9–29. doi:10.3322/Caac.21208.
3. Center MM, Jemal A, Smith RA, Ward E. Worldwide variations in colorectal cancer. CA Cancer J Clin. 2009;59(6):366–78. doi:10.3322/caac.20038.
4. Wei YS, Lu JC, Wang L, Lan P, Zhao HJ, Pan ZZ, et al. Risk factors for sporadic colorectal cancer in southern Chinese. World J Gastroenterol. 2009;15(20):2526–30.
5. Zheng ZX, Zheng RS, Zhang SW, Chen WQ. Colorectal cancer incidence and mortality in China, 2010. Asian Pac J Cancer Prev. 2014;15(19):8455–60.
6. DeSantis CE, Lin CC, Mariotto AB, Siegel RL, Stein KD, Kramer JL, et al. Cancer treatment and survivorship statistics, 2014. CA Cancer J Clin. 2014;64(4):252–71. doi:10.3322/caac.21235.
7. Chen AJ, Zhou G, Juan T, Colicos SM, Cannon JP, Cabriera-Hansen M, et al. The dual specificity JKAP specifically activates the c-Jun N-terminal kinase pathway. J Biol Chem. 2002;277(39):36592–601. doi:10.1074/jbc.M200453200.
8. Chang L, Karin M. Mammalian MAP kinase signalling cascades. Nature. 2001;410(6824):37–40. doi:10.1038/35065000.
9. Wagner EF, Nebreda AR. Signal integration by JNK and p38 MAPK pathways in cancer development. Nat Rev Cancer. 2009;9(8):537–49. doi:10.1038/nrc2694.
10. Pearson G, Robinson F, Beers Gibson T, Xu BE, Karandikar M, Berman K, et al. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev. 2001;22(2):153–83. doi:10.1210/edrv.22.2.0428.
11. Sekine Y, Tsuji S, Ikeda O, Sato N, Aoki N, Aoyama K, et al. Regulation of STAT3-mediated signaling by LMW-DSP2. Oncogene. 2006;25(42):5801–6. doi:10.1038/sj.onc.1209578.
12. Lee W, Jiang Z, Liu J, Haverty PM, Guan Y, Stinson J, et al. The mutation spectrum revealed by paired genome sequences from a lung cancer patient. Nature. 2010;465(7297):473–7. doi:10.1038/nature09004.
13. Li JP, Fu YN, Chen YR, Tan TH. JNK pathway-associated phosphatase dephosphorylates focal adhesion kinase and suppresses cell migration. J Biol Chem. 2010;285(8):5472–8. doi:10.1074/jbc.M109.060186.
14. Jantus CLL, Lewintre E, Reinoso Martin C, Montaner D, Marin M, Jose Terol M, et al. Analysis of chronic lymphotic leukemia transcriptomic profile: differences between molecular subgroups. Leuk Lymphoma. 2009;50(1):68–79. doi:10.1080/10428190802541807.
15. Bernard-Pierrot I, Gruel N, Stransky N, Vincent-Salomon A, Reyal F, Raynal V, et al. Characterization of the recurrent 8p11-12 amplicon identifies PPAPDC1B, a phosphatase protein, as a new therapeutic target in breast cancer. Cancer Res. 2008;68(17):7165–75. doi:10.1158/0008-5472.CAN-08-1360.
16. Edge SB, Byrd DR, Compton C, Fritz AG, Greene FL, Trotti A. AJCC cancer staging manual. 7th ed. NewYork: Springer; 2010.
17. Shen Y, Luche R, Wei B, Gordon ML, Diltz CD, Tonks NK. Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1. Proc Natl Acad Sci U S A. 2001;98(24):13613–8. doi:10.1073/pnas.231499098.
18. Sekine Y, Ikeda O, Hayakawa Y, Tsuji S, Imoto S, Aoki N, et al. DUSP22/LMW-DSP2 regulates estrogen receptor-alpha-mediated signaling through dephosphorylation of Ser-118. Oncogene. 2007;26(41):6038–49. doi:10.1038/sj.onc.1210426.
19. Hoekstra E, Peppelenbosch MP, Fuhler GM. The role of protein tyrosine phosphatases in colorectal cancer. Biochim Biophys Acta. 2012;1826(1):179–88. doi:10.1016/j.bbcan.2012.04.001.
20. Hoekstra E, Kodach LL, Das AM, Ruela-de-Sousa RR, Ferreira CV, Hardwick JC, et al. Low molecular weight protein tyrosine phosphatase (LMWPTP) upregulation mediates malignant potential in colorectal cancer. Oncotarget. 2015;6(10):8300–12.
21. Zlobec I, Minoo P, Karamitopoulou E, Peros G, Patsouris ES, Lehmann F, et al. Role of tumor size in the pre-operative management of rectal cancer patients. BMC Gastroenterol. 2010;10:61. doi:10.1186/1471-230X-10-61.