Extracellular vesicles derived from bone marrow mesenchymal stem cells protect against experimental colitis via attenuating colon inflammation, oxidative stress and apoptosis

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Yang, Jia ^a   Liu, Xing Xing ^a   Fan, Heng ^a   Tang, Qing ^a   Shou, Zhe Xing ^a   Zuo, Dong Mei ^a   Zou, Zhou ^a   Xu, Meng ^a   Chen, Qian Yun ^a   Peng, Ying ^a   Deng, Shuang Jiao ^a   Liu, Yu Jin ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYCLOOXYGENASE 2; GLUTATHIONE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; MALONALDEHYDE; MESSENGER RNA; MYELOPEROXIDASE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; TRINITROBENZENESULFONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MESENCHYMAL STEM CELL DERIVED EXTRACELLULAR VESICLE; CELLULAR DISTRIBUTION; COLITIS; CONTROLLED STUDY; DIGESTIVE SYSTEM DISEASE ASSESSMENT; DISEASE ACTIVITY INDEX; DISEASE SEVERITY; DOWN REGULATION; ENZYME ACTIVITY; EXPERIMENTAL COLITIS; HISTOPATHOLOGY; MALE; MESENCHYMAL STEM CELL; NONHUMAN; OXIDATIVE STRESS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; THERAPY EFFECT; ANIMAL; CELL CULTURE; COLITIS, ULCERATIVE; CYTOLOGY; DISEASE MODEL; EXOSOME; GENETICS; IMMUNOLOGY; INFLAMMATION; MESENCHYMAL STROMA CELL; METABOLISM; PARACRINE SIGNALING; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; CELLS, CULTURED; COLITIS, ULCERATIVE; CYTOKINES; DISEASE MODELS, ANIMAL; EXTRACELLULAR VESICLES; INFLAMMATION; MALE; MESENCHYMAL STROMAL CELLS; OXIDATIVE STRESS; PARACRINE COMMUNICATION; RATS; RATS, SPRAGUE-DAWLEY; TRINITROBENZENESULFONIC ACID;

EID: 84949058412     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0140551     Document Type: Article

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