Telmisartan attenuates colon inflammation, oxidative perturbations and apoptosis in a rat model of experimental inflammatory bowel disease

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Arab, Hany H ^a   Al Shorbagy, Muhammad Y ^a   Abdallah, Dalaal M ^a   Nassar, Noha N ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYCLOOXYGENASE 2; CYTOCHROME C; GLUTATHIONE; GLUTATHIONE PEROXIDASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; LIPID PEROXIDE; MESSENGER RNA; MYELOPEROXIDASE; NITRIC OXIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN E2; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; TELMISARTAN; TRANSCRIPTION FACTOR RELA; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANTIOXIDANT; BENZIMIDAZOLE DERIVATIVE; BENZOIC ACID DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NOS2 PROTEIN, RAT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; COLITIS; COLON INJURY; COLON LENGHT; COLON WEIGHT; CONTROLLED STUDY; DIGESTIVE TRACT PARAMETERS; DISEASE ACTIVITY; DISEASE MODEL; DISEASE SEVERITY; DOWN REGULATION; DRUG ACTIVITY; ENZYME ACTIVITY; EXPERIMENTAL INFLAMMATORY BOWEL DISEASE; GENE EXPRESSION; HISTOPATHOLOGY; LEUKOCYTE MIGRATION; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; ORGAN WEIGHT; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; UPREGULATION; ANIMAL; CHEMICALLY INDUCED; COLON; DRUG EFFECTS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INFLAMMATORY BOWEL DISEASES; LIPID PEROXIDATION; METABOLISM; PATHOLOGY; WISTAR RAT;

ANGIOTENSIN II TYPE 2 RECEPTOR BLOCKERS; ANIMALS; ANTIOXIDANTS; APOPTOSIS; BENZIMIDAZOLES; BENZOATES; COLITIS; COLON; DISEASE MODELS, ANIMAL; GLUTATHIONE; GLUTATHIONE PEROXIDASE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INFLAMMATORY BOWEL DISEASES; LIPID PEROXIDATION; MALE; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; RATS; RATS, WISTAR; RNA, MESSENGER; SUPEROXIDE DISMUTASE; TRINITROBENZENESULFONIC ACID;

EID: 84901362590     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097193     Document Type: Article

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