TRAF5-mediated Lys-63-linked polyubiquitination plays an essential role in positive regulation of RORγt in promoting IL-17A expression

Journal of Biological Chemistry

Volumn 290, Issue 48, 2015, Pages 29086-29094

  Wang, Xiuwen ^a   Yang, Jing ^b   Han, Lei ^a   Zhao, Kaixia ^a   Wu, Qingsi ^c   Bao, Liming ^d   Li, Zhiyuan ^b   Lv, Ling ^a   Li, Bin ^b  

^a FUDAN UNIVERSITY   (China)

^b INSTITUTE PASTEUR OF SHANGHAI   (China)

^c ANHUI MEDICAL UNIVERSITY   (China)

^d DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY;

AUTOIMMUNE DISEASE; CELL FUNCTIONS; POLYUBIQUITINATION; SYSTEMIC LUPUS ERYTHEMATOSUS; UBIQUITINATION;

BIOLOGY;

INTERLEUKIN 17; LYSINE; RETINOID RELATED ORPHAN RECEPTOR GAMMA; RETINOID RELATED ORPHAN RECEPTOR GAMMA T; RING FINGER PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 5; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; IL17A PROTEIN, HUMAN; RORC PROTEIN, HUMAN;

ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; INFLAMMATION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TARGETING; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; TH17 CELL; UBIQUITINATION; BIOSYNTHESIS; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY;

GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; INTERLEUKIN-17; LYSINE; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; PROTEIN STABILITY; TH17 CELLS; TNF RECEPTOR-ASSOCIATED FACTOR 5; UBIQUITINATION;

EID: 84949034235     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.664573     Document Type: Article

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