Acidosis-induced dysfunction of cortical GABAergic neurons through astrocyte-related excitotoxicity

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Huang, Li ^a   Zhao, Shidi ^a   Lu, Wei ^c   Guan, Sudong ^a   Zhu, Yan ^a   Wang, Jin Hui ^b  

^a BENGBU MEDICAL COLLEGE   (China)

^b INSTITUTE OF BIOPHYSICS   (China)

^c QINGDAO UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; AMPA RECEPTOR; GLUTAMATE TRANSPORTER; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; VOLTAGE GATED SODIUM CHANNEL; 4 AMINOBUTYRIC ACID RECEPTOR;

ACIDIFICATION; ACIDOSIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE RELATED EXCITOTOXICITY; CELL DAMAGE; CELL FUNCTION; COMPARATIVE STUDY; CONTROLLED STUDY; EXCITATORY SYNAPSE; EXCITATORY SYNAPTIC TRANSMISSION; EXCITOTOXICITY; EXTRACELLULAR ACIDIFICATION; EXTRACELLULAR ACIDOSIS; GABAERGIC NEURON DYSFUNCTION; GLUTAMATE TRANSPORTER CURRENT; INTRACELLULAR ACIDIFICATION; INTRACELLULAR ACIDOSIS; MOLECULAR DYNAMICS; MOUSE; NERVOUS SYSTEM PARAMETERS; NONHUMAN; REFRACTORY PERIOD; SPIKE PRODUCTION; SPONTANEOUS INHIBITORY POSTSYNAPTIC CURRENT; SYNAPSE; SYNAPTIC OUTPUT; SYNAPTIC TRANSMISSION; UPREGULATION; ANIMAL; BRAIN CORTEX; METABOLIC ENCEPHALOPATHY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; TRANSGENIC MOUSE;

ACIDOSIS; ANIMALS; BRAIN DISEASES, METABOLIC; CEREBRAL CORTEX; GABAERGIC NEURONS; MICE; MICE, TRANSGENIC; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 84949033999     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0140324     Document Type: Article

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