MiR-486 and miR-92a identified in circulating HDL discriminate between stable and vulnerable coronary artery disease patients

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Niculescu, Loredan S ^a   Simionescu, Natalia ^a,b   Sanda, Gabriela M ^a   Carnuta, Mihaela G ^a   Stancu, Camelia S ^a   Popescu, Andreea C ^c   Popescu, Mihaela R ^c   Vlad, Adelina ^c   Dimulescu, Doina R ^c   Simionescu, Maya ^a   Sima, Anca V ^a  

^a INSTITUTE OF CELLULAR BIOLOGY AND PATHOLOGY NICOLAE SIMIONESCU   (Romania)

^b PETRU PONI INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Romania)

^c CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN E; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; MICRORNA; MICRORNA 122; MICRORNA 125A; MICRORNA 146A; MICRORNA 33A; MICRORNA 486; MICRORNA 92A; TROPONIN I; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC ASSOCIATION; HEART INFARCTION; HUMAN; LIPID METABOLISM; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; STABLE ANGINA PECTORIS; UNSTABLE ANGINA PECTORIS; VULNERABLE POPULATION;

EID: 84949032986     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0140958     Document Type: Article

References (37)

1. Lusis AJ. Atherosclerosis. Nature. 2000; 407(6801):233-41. Epub 2000/09/23. doi: 10.1038/35025203 PMID: 11001066; PubMed Central PMCID: PMC2826222.
2. Hansson GK, Hermansson A. The immune system in atherosclerosis. Nat Immunol. 2011; 12(3):204-12. Epub 2011/02/16. doi: 10.1038/ni.2001 PMID: 21321594.
3. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004; 116(2):281-97. Epub 2004/01/28. doi: 10.1016/S0092-8674(04)00045-5 PMID: 14744438.
4. Ono K, Kuwabara Y, Han J. MicroRNAs and cardiovascular diseases. FEBS J. 2011; 278(10):1619-33. Epub 2011/03/15. doi: 10.1111/j.1742-4658.2011.08090.x PMID: 21395978; PubMed Central PMCID: PMC3087823.
5. Kroh EM, Parkin RK, Mitchell PS, Tewari M. Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR). Methods. 2010; 50(4):298-301. Epub 2010/02/12. doi: 10.1016/j.ymeth.2010.01.032 PMID: 20146939.
6. Vickers KC, Palmisano BT, Shoucri BM, Shamburek RD, Remaley AT. MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. Nat Cell Biol. 2011; 13(4):423-33. Epub 2011/03/23. doi: 10.1038/ncb2210 PMID: 21423178; PubMed Central PMCID: PMC3074610.
7. Zampetaki A, Willeit P, Drozdov I, Kiechl S, Mayr M. Profiling of circulating microRNAs: from single biomarkers to re-wired networks. Cardiovasc Res. 2012; 93(4):555-62. Epub 2011/10/27. doi: 10.1093/cvr/cvr266 PMID: 22028337; PubMed Central PMCID: PMC3291086.
8. Madrigal-Matute J, Rotllan N, Aranda JF, Fernandez-Hernando C. MicroRNAs and atherosclerosis. Curr Atheroscler Rep. 2013; 15(5):322. Epub 2013/03/21. doi: 10.1007/s11883-013-0322-z PMID: 23512606.
9. Rayner KJ, Fernandez-Hernando C, Moore KJ. MicroRNAs regulating lipid metabolism in atherogene-sis. Thromb Haemost. 2012; 107(4):642-7. Epub 2012/01/26. doi: 10.1160/TH11-10-0694 PMID: 22274626; PubMed Central PMCID: PMC3618663.
10. Guay C, Regazzi R. Circulating microRNAs as novel biomarkers for diabetes mellitus. Nat Rev Endocrinol. 2013; 9(9):513-21. Epub 2013/05/01. doi: 10.1038/nrendo.2013.86 PMID: 23629540.
11. Jaguszewski M, Osipova J, Ghadri JR, Napp LC, Widera C, Franke J, et al. A signature of circulating microRNAs differentiates takotsubo cardiomyopathy from acute myocardial infarction. Eur Heart J. 2014; 35(15):999-1006. Epub 2013/09/21. doi: 10.1093/eurheartj/eht392 PMID: 24046434; PubMed Central PMCID: PMC3985061.
12. Creemers EE, Tijsen AJ, Pinto YM. Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease? Circ Res. 2012; 110(3):483-95. Epub 2012/02/04. doi: 10.1161/CIRCRESAHA.111.247452 PMID: 22302755.
13. van Empel VP, DeWindt LJ, da Costa Martins PA. Circulating miRNAs: reflecting or affecting cardiovascular disease? Curr Hypertens Rep. 2012; 14(6):498-509. Epub 2012/09/22. doi: 10.1007/s11906-012-0310-7 PMID: 22996205.
14. Wagner J, Riwanto M, Besler C, Knau A, Fichtlscherer S, Roxe T, et al. Characterization of levels and cellular transfer of circulating lipoprotein-bound microRNAs. Arterioscler Thromb Vasc Biol. 2013; 33 (6):1392-400. Epub 2013/04/06. doi: 10.1161/ATVBAHA.112.300741 PMID: 23559634.
15. Kaudewitz D, Lee R, Willeit P, McGregor R, Markus HS, Kiechl S, et al. Impact of intravenous heparin on quantification of circulating microRNAs in patients with coronary artery disease. Thromb Haemost. 2013; 110(3):609-15. Epub 2013/06/28. doi: 10.1160/TH13-05-0368 PMID: 23803974.
16. Rozenberg O, Shih DM, Aviram M. Paraoxonase 1 (PON1) attenuates macrophage oxidative status: studies in PON1 transfected cells and in PON1 transgenic mice. Atherosclerosis. 2005; 181(1):9-18. Epub 2005/06/09. doi: 10.1016/j.atherosclerosis.2004.12.030 PMID: 15939049.
17. Kypreos KE, van Dijk KW, Havekes LM, Zannis VI. Generation of a recombinant apolipoprotein E variant with improved biological functions: hydrophobic residues (LEU-261, TRP-264, PHE-265, LEU-268, VAL-269) of apoE can account for the apoE-induced hypertriglyceridemia. J Biol Chem. 2005; 280 (8):6276-84. Epub 2004/12/04. doi: 10.1074/jbc.M413458200 PMID: 15576362.
18. Sima AV, Botez GM, Stancu CS, Manea A, Raicu M, Simionescu M. Effect of irreversibly glycated LDL in human vascular smooth muscle cells: lipid loading, oxidative and inflammatory stress. J Cell Mol Med. 2010; 14(12):2790-802. Epub 2009/10/13. doi: 10.1111/j.1582-4934.2009.00933.x PMID: 19818091; PubMed Central PMCID: PMC3822729.
19. Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, Pogosova-Agadjanyan EL, et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci USA. 2008; 105 (30):10513-8. Epub 2008/07/30. doi: 10.1073/pnas.0804549105 PMID: 18663219; PubMed Central PMCID: PMC2492472.
20. Fichtlscherer S, De Rosa S, Fox H, Schwietz T, Fischer A, Liebetrau C, et al. Circulating microRNAs in patients with coronary artery disease. Circ Res. 2010; 107(5):677-84. Epub 2010/07/03. doi: 10.1161/CIRCRESAHA.109.215566 PMID: 20595655.
21. Zampetaki A, Mayr M. Analytical challenges and technical limitations in assessing circulating miRNAs. Thromb Haemost. 2012; 108(4):592-8. Epub 2012/05/26. doi: 10.1160/TH12-02-0097 PMID: 22627831.
22. Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc. 2008; 3(6):1101-8. Epub 2008/06/13. doi: 10.3410/f.5500956.5467055 PMID: 18546601.
23. Guo M, Mao X, Ji Q, Lang M, Li S, Peng Y, et al. miR-146ain PBMCs modulatesTh1 function in patients with acute coronary syndrome. Immunol Cell Biol. 2010; 88(5):555-64. Epub 2010/03/03. doi: 10.1038/icb.2010.16 PMID: 20195282.
24. Simionescu N, Niculescu LS, Sanda GM, Margina D, Sima AV. Analysis of circulating microRNAs that are specifically increased in hyperlipidemic and/or hyperglycemic sera. Mol Biol Rep. 2014; 41 (9):5765-73. Epub 2014/06/15. doi: 10.1007/s11033-014-3449-2 PMID: 24928089.
25. Meder B, Keller A, Vogel B, Haas J, Sedaghat-Hamedani F, Kayvanpour E, et al. MicroRNA signatures in total peripheral blood as novel biomarkers for acute myocardial infarction. Basic Res Cardiol. 2011; 106(1):13-23. Epub 2010/10/05. doi: 10.1007/s00395-010-0123-2 PMID: 20886220.
26. Lai CT, Ng EK, Chow PC, Kwong A, Cheung YF. Circulating microRNA expression profile and systemic right ventricular function in adults after atrial switch operation for complete transposition of the great arteries. BMC Cardiovasc Disord. 2013; 13:73. Epub 2013/09/18. doi: 10.1186/1471-2261-13-73 PMID: 24040857; PubMed Central PMCID: PMC3847493.
27. Ren J, Zhang J, Xu N, Han G, Geng Q, Song J, et al. Signature of circulating microRNAs as potential biomarkers in vulnerable coronary artery disease. PLoS One. 2013; 8(12):e80738. Epub 2013/12/18. doi: 10.1371/journal.pone.0080738 PMID: 24339880; PubMed Central PMCID: PMC3855151.
28. Bonauer A, Carmona G, Iwasaki M, Mione M, Koyanagi M, Fischer A, et al. MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice. Science. 2009; 324(5935):1710-3. Epub 2009/05/23. doi: 10.1126/science.1174381 PMID: 19460962.
29. Loyer X, Potteaux S, Vion AC, Guerin CL, Boulkroun S, Rautou PE, et al. Inhibition of microRNA-92a prevents endothelial dysfunction and atherosclerosis in mice. Circ Res. 2014; 114(3):434-43. Epub 2013/11/21. doi: 10.1161/CIRCRESAHA.114.302213 PMID: 24255059.
30. Haraguchi Y, Toh R, Hasokawa M, Nakajima H, Honjo T, Otsui K, et al. Serum myeloperoxidase/para-oxonase 1 ratio as potential indicator of dysfunctional high-density lipoprotein and risk stratification in coronary artery disease. Atherosclerosis. 2014; 234(2):288-94. Epub 2014/04/08. doi: 10.1016/j. atherosclerosis.2014.03.009 PMID: 24704632.
31. Chang J, Nicolas E, Marks D, Sander C, Lerro A, Buendia MA, et al. miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1. RNABiol. 2004; 1(2):106-13. Epub 2006/12/21. doi: 10.4161/rna.1.2.1066 PMID: 17179747.
32. Gao W, He HW, Wang ZM, Zhao H, Lian XQ, Wang YS, et al. Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease. Lipids Health Dis. 2012; 11:55. Epub 2012/05/17. doi: 10.1186/1476-511X-11-55 PMID: 22587332; PubMed Central PMCID: PMC3439335.
33. Oerlemans MI, Mosterd A, Dekker MS, de Vrey EA, van Mil A, Pasterkamp G, et al. Early assessment of acute coronary syndromes in the emergency department: the potential diagnostic value of circulating microRNAs. EMBOMol Med. 2012; 4(11):1176-85. Epub 2012/10/02. doi: 10.1002/emmm.201201749 PMID: 23023917; PubMed Central PMCID: PMC3494874.
34. Bidzhekov K, Gan L, Denecke B, Rostalsky A, Hristov M, Koeppel TA, et al. microRNA expression signatures and parallels between monocyte subsets and atherosclerotic plaque in humans. Thromb Hae-most. 2012; 107(4):619-25. Epub 2012/03/01. doi: 10.1160/TH11-09-0607 PMID: 22370758.
35. Tabet F, Vickers KC, Cuesta Torres LF, Wiese CB, Shoucri BM, Lambert G, et al. HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells. Nat Commun. 2014; 5:3292. Epub 2014/03/01. doi: 10.1038/ncomms4292 PMID: 24576947.
36. Rayner KJ, Moore KJ. MicroRNA control of high-density lipoprotein metabolism and function. Circ Res. 2014; 114(1):183-92. Epub 2014/01/05. doi: 10.1161/CIRCRESAHA.114.300645 PMID: 24385511; PubMed Central PMCID: PMC4367480.
37. Ono K, Horie T, Nishino T, Baba O, Kuwabara Y, Kimura T. MicroRNAs and High-Density Lipoprotein Cholesterol Metabolism. Int Heart J. 2015; 56(4):365-71. Epub 2015/06/19. doi: 10.1536/ihj.15-019 PMID: 26084456.