Signature of circulating MicroRNAs As potential biomarkers in vulnerable coronary artery disease

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Ren, Jingyi ^a   Zhang, Jing ^a   Xu, Ning ^b   Han, Guanping ^a   Geng, Qiang ^a   Song, Junxian ^a   Li, Sufang ^a   Zhao, Jianqing ^c   Chen, Hong ^a  

^a PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^b KAROLINSKA INSTITUTE   (Sweden)

^c NATIONAL ENGINEERING RESEARCH CENTER FOR BEIJING BIOCHIP TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CD31 ANTIGEN; LIPOCORTIN 5; MICRORNA; MICRORNA 106B; MICRORNA 126; MICRORNA 17; MICRORNA 21; MICRORNA 25; MICRORNA 451; MICRORNA 590 5P; MICRORNA 92A; UNCLASSIFIED DRUG; TRANSCRIPTOME;

ADULT; ARTICLE; CLINICAL EFFECTIVENESS; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FEMALE; HIGH RISK PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; PARTICLE SIZE; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; RNA FINGERPRINTING; RNA ISOLATION; SENSITIVITY AND SPECIFICITY; UPREGULATION; BLOOD; GENETICS; MEMBRANE MICROPARTICLE; METABOLISM; MIDDLE AGED; PATHOLOGY; REPRODUCIBILITY; UNSTABLE ANGINA PECTORIS;

ANGINA, UNSTABLE; BIOLOGICAL MARKERS; CELL-DERIVED MICROPARTICLES; CORONARY ARTERY DISEASE; FEMALE; HUMANS; MALE; MICRORNAS; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; TRANSCRIPTOME;

EID: 84891929937     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080738     Document Type: Article

References (33)

1. Finn AV, Nakano M, Narula J, Kolodgie FD, Virmani R (2010) Concept of vulnerable/unstable plaque. Arterioscler Thromb Vasc Biol 30:1282-292.
2. Schaar JA, Mastik F, Regar E, den Uil CA, Gijsen FJ, et al. (2007) Current diagnostic modalities for vulnerable plaque detection. Curr Pharm Des 13:995-1001. (Pubitemid 46696555)
3. Ambrose JA, Srikanth S (2010) Vulnerable plaques and patients: improving prediction of future coronary events. Am J Med 123:10-16.
4. Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281-297.
5. Kozomara A, Griffiths-Jones S (2011) miRBase: integrating microRNA annotation and deep-sequencing data. NAR 39:D152-D157.
6. Small EM, Olson EN (2011) Pervasive roles of microRNAs in cardiovascular biology. Nature 469:336-342.
7. Haver VG, Slart RH, Zeebregts CJ, Peppelenbosch MP, Tio RA (2010) Rupture of vulnerable atherosclerotic plaques: microRNAs conducting the orchestra? Trends Cardiovasc Med 20:65-71.
8. Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, et al. (2008) Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci USA 105:10513-10518.
9. Fichtlscherer S, Zeiher AM, Dimmeler S (2011) Circulating microRNAs: biomarkers or mediators of cardiovascular diseases? Arterioscler Thromb Vasc Biol 31:2383-2390.
10. Diehl P, Fricke A, Sander L, Stamm J, Bassler N, et al. (2012) Microparticles: major transport vehicles for distinct miRNAs in circulation. Cardiovasc Res 93:633-644.
11. Wang GK, Zhu JQ, Zhang JT, Li Q, Li Y, et al. (2010) Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans. Eur Heart J 31:659-666.
12. Fichtlscherer S, De Rosa S, Fox H, Schwietz T, Fischer A, et al. (2010) Circulating microRNAs in patients with coronary artery disease. Circ Res 107:677-684.
13. Rautou PE, Leroyer AS, Ramkhelawon B, Devue C, Duflaut D, et al. (2011) Microparticles from human atherosclerotic plaques promote endothelial ICAM-1-dependent monocyte adhesion and transendothelial migration. Circ Res 108:335-343.
14. Sinning JM, Losch J, Walenta K, Böhm M, Nickenig G, et al. (2011) Circulating CD31+/Annexin V+ microparticles correlate with cardiovascular outcomes. Eur Heart J 32:2034-2041.
15. Werner N, Wassmann S, Ahlers P, Kosiol S, Nickenig G (2006) Circulating CD31+/annexin V+ apoptotic microparticles correlate with coronary endothelial function in patients with coronary artery disease. Arterioscler Thromb Vasc Biol 26:112-116. (Pubitemid 43732236)
16. Horstman LL, Jy W, Jimenez JJ, Ahn YS (2004) Endothelial microparticles as markers of endothelial dysfunction. Front Biosci 9:1118-1135. (Pubitemid 39060833)
17. Zampetaki A, Willeit P, Drozdov I, Kiechl S, Mayr M (2012) Profiling of circulating microRNAs: from single biomarkers to re-wired networks. Cardiovasc Res 93:555-562.
18. Yao R, Ma Y, Du Y, Liao M, Li H, et al. (2011) The altered expression of inflammation-related microRNAs with microRNA-155 expression correlates with Th17 differentiation in patients with acute coronary syndrome. Cell Mol Immunol 8:486-495.
19. * with elevated expression in patients with pulmonary tuberculosis. Mol Immunol 48:1084-1090.
20. Chen WJ, Yin K, Zhao GJ, Fu YC, Tang CK (2012) The magic and mystery of MicroRNA-27 in atherosclerosis. Atherosclerosis 222:314-323.
21. Rippe C, Blimline M, Magerko KA, Lawson BR, LaRocca TJ, et al. (2012) MicroRNA changes in human arterial endothelial cells with senescence: relation to apoptosis, eNOS and inflammation. Exp Gerontol 47:45-51.
22. Villeneuve LM, Kato M, Reddy MA, Wang M, Lanting L, et al. (2010) Enhanced levels of microRNA-125b in vascular smooth muscle cells of diabetic db/db mice lead to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1. Diabetes 59:2904-2915.
23. Vickers KC, Palmisano BT, Shoucri BM, Shamburek RD, Remaley AT (2011) MicroRNAs are transported in plasma and delivered to recipient cells by highdensity lipoproteins. Nat Cell Biol 13:423-433.
24. Petrocca F, Vecchione A, Croce CM (2008) The miR-106b-25 and miR-17-92 clusters are emerging as key modulators of TGF-b signaling in gastrointestinal and other tumors, interfering with cell cycle arrest and apoptosis when overexpressed in cancer cells. Cancer Res 68:8191-8194.
25. Lutgens E, Daemen MJ (2001) Transforming growth factor-b: a local or systemic mediator of plaque stability? Circ Res 89:853-855. (Pubitemid 34627888)
26. Bonauer A, Carmona G, Iwasaki M, Mione M, Koyanagi M, et al. (2009) MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice. Science 324:1710-1713.
27. Gabriely G, Wurdinger T, Kesari S, Esau CC, Burchard J, et al. (2008) MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol Cell Biol 28:5369-5380.
28. Zernecke A, Bidzhekov K, Noels H, Shagdarsuren E, Gan L, et al. (2009) Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Sci Signal 2:ra81.
29. *. PLoS One 6:e25946.
30. Bandres E, Bitarte N, Arias F, Agorreta J, Fortes P, et al. (2009) MicroRNA-451 regulates macrophage migration inhibitory factor production and proliferation of gastrointestinal cancer cells. Clin Cancer Res 15:2281-2290.
31. Tian Y, Nan Y, Han L, Zhang A, Wang G, et al. (2012) MicroRNA-451 downregulates the PI3K/AKT pathway through CAB39 in human glioma. Int J Oncol 40:1105-1112.
32. * species and their role in myeloid cells. Blood 118:3350-3358.
33. Yuana Y, Bertina RM, Osanto S (2011) Pre-analytical and analytical issues in the analysis of blood microparticles. Thromb Haemost 105:39 08.