Relationship between sperm aneuploidy, sperm DNA integrity, chromatin packaging, traditional semen parameters, and recurrent pregnancy loss Presented at the 17th World Congress on in Vitro Fertilization, Tunis, Tunisia, on September 4-7, 2013.

Fertility and Sterility

Volumn 105, Issue 1, 2016, Pages 58-64

  Zidi Jrah, Ines ^a   Hajlaoui, Amani ^a   Mougou Zerelli, Soumaya ^a   Kammoun, Molka ^a   Meniaoui, Imene ^a   Sallem, Amira ^a   Brahem, Sonia ^a   Fekih, Meriem ^a   Bibi, Mohammed ^a   Saad, Ali ^a   Ibala Romdhane, Samira ^a  

^a FARHAT HACHED HOSPITAL   (Tunisia)

Author keywords

aneuploidy; DNA damage; pregnancy loss; Spermatozoa

Indexed keywords

ANILINE; DNA; SPERM DNA; UNCLASSIFIED DRUG;

ACROSOME; ADULT; ANEUPLOIDY; ARTICLE; CHROMATIN CONDENSATION; CHROMOSOME 18; CLINICAL ARTICLE; CONTROLLED STUDY; DESCRIPTIVE RESEARCH; DISOMY; DNA DAMAGE; DNA FRAGMENTATION; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; RECURRENT ABORTION; SEMEN ANALYSIS; SPERM ANEUPLOIDY; SPERMATOZOON ABNORMALITY; SPERMATOZOON HEAD; SPERMATOZOON MOTILITY; TUNEL ASSAY; X CHROMOSOME; Y CHROMOSOME; ABORTION, HABITUAL; CASE CONTROL STUDY; CELL SHAPE; CHROMATIN ASSEMBLY AND DISASSEMBLY; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; PREGNANCY; RISK ASSESSMENT; RISK FACTOR; SPERMATOZOON; SPERMATOZOON COUNT; YOUNG ADULT;

ABORTION, HABITUAL; ADULT; ANEUPLOIDY; CASE-CONTROL STUDIES; CELL SHAPE; CHROMATIN ASSEMBLY AND DISASSEMBLY; DNA DAMAGE; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MIDDLE AGED; PREGNANCY; RISK ASSESSMENT; RISK FACTORS; SPERM COUNT; SPERM MOTILITY; SPERMATOZOA; YOUNG ADULT;

EID: 84949008625     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2015.09.041     Document Type: Article

References (43)

1. Practice Committee of American Society for Reproductive Medicine Definitions of infertility and recurrent pregnancy loss: a committee opinion Fertil Steril 99 2013 63
2. E.C. Larsen, O.B. Christiansen, A.M. Kolte, and N. Macklon New insights into mechanisms behind miscarriage BMC Med 11 2013 154
3. Royal College of Obstetricians and Gynaecologists The investigation and treatment of couples with recurrent first-trimester and second-trimester miscarriage 2011 Royal College of Obstetricians and Gynaecologists (RCOG) London (UK) (Green-top guideline; no. 17)
4. L. Zhang, L. Wang, X. Zhang, G. Xu, W. Zhang, K. Wang, and et al. Sperm chromatin integrity may predict future fertility for unexplained recurrent spontaneous abortion patients Int J Androl 35 2012 752 757
5. T.C. Li, M. Makris, M. Tomsu, E. Tuckerman, and S. Laird Recurrent miscarriage: aetiology, management and prognosis Hum Reprod Update 8 2002 463 481
6. G. Kovalevsky, C.R. Gracia, J.A. Berlin, M.D. Sammel, and K.T. Barnhart Evaluation of the association between hereditary thrombophilias and recurrent pregnancy loss: a meta-analysis Arch Intern Med 164 2004 558 563
7. A.S. Devi Wold, N. Pham, and A. Arici Anatomic factors in recurrent pregnancy loss Semin Reprod Med 24 2006 25 32
8. B. Toth, U. Jeschke, N. Rogenhofer, C. Scholz, W. Würfel, C.J. Thaler, and et al. Recurrent miscarriage: current concepts in diagnosis and treatment J Reprod Immunol 85 2010 25 32
9. E.E. Puscheck, and R.S. Jeyendran The impact of male factor on recurrent pregnancy loss Curr Opin Obstet Gynecol 19 2007 222 228
10. L. Nanassy, and D.T. Carrell Paternal effects on early embryogenesis J Exp Clin Assist Reprod 5 2008 2
11. A.M. Gil-Villa, W. Cardona-Maya, A. Agarwal, R. Sharma, and A. Cadavid Assessment of sperm factors possibly involved in early recurrent pregnancy loss Fertil Steril 94 2010 1465 1472
12. G. Collodel, V. Giannerini, A.N. Pascarelli, M.G. Federico, F. Comodo, and E. Moretti TEM and FISH studies in sperm from men of couples with recurrent pregnancy loss Andrologia 41 2009 352 360
13. A. Agarwal, and T.M. Said Role of sperm chromatin abnormalities and DNA damage in male infertility Hum Reprod Update 9 2003 331 345
14. F. Absalan, and A. Ghannadi Value of sperm chromatin dispersion test in couples with unexplained recurrent abortion J Assist Reprod Genet 29 2012 11 14
15. C. Rubio, C. Simon, J. Blanco, F. Vidal, Y. Minguez, J. Egozcue, and et al. Implications of sperm chromosome abnormalities in recurrent miscarriage J Assist Reprod Genet 16 1999 253 258
16. S. Munné, M. Alikani, G. Tomkin, J. Grifo, and J. Cohen Embryo morphology, developmental rates, and maternal age are correlated with chromosome abnormalities Fertil Steril 64 1995 382 391
17. World Health Organization WHO laboratory manual for the examination and processing of human semen 5th ed. 2010 WHO Geneva, Switzerland
18. J. Auger, F. Eustache, A.G. Andersen, D.S. Irvine, N. Jørgensen, N.E. Skakkebaek, and et al. Sperm morphological defects related to environment, lifestyle and medical history of 1001 male partners of pregnant women from four European cities Hum Reprod 16 2001 2710 2717
19. R.K. Sharma, E. Sabanegh, R. Mahfouz, S. Gupta, A. Thiyagarajan, and A. Agarwal TUNEL as a test for sperm DNA damage in the evaluation of male infertility Urology 76 2010 1380 1386
20. M. Sergerie, G. Laforest, L. Bujan, F. Bissonnette, and G. Bleau Sperm DNA fragmentation: threshold value in male fertility Hum Reprod 20 2005 3446 3451
21. N. Hofmann, and B. Hilscher Use of aniline blue to assess chromatin condensation in morphologically normal spermatozoa in normal and infertile men Hum Reprod 6 1991 979 982
22. A. Sellami, N. Chakroun, S. Ben Zarrouk, H. Sellami, S. Kebaili, T. Rebai, and et al. Assessment of chromatin maturity in human spermatozoa: useful aniline blue assay for routine diagnosis of male infertility Adv Urol 2013 2013 578631
23. P. Kavitha, and S.S. Malini Positive association of sperm dysfunction in the pathogenesis of recurrent pregnancy loss J Clin Diagn Res 8 2014 7 10
24. S. Sbracia, G. Cozza, J.A. Grasso, M. Mastrone, and F. Scarpellini Semen parameters and sperm morphology in men in unexplained recurrent spontaneous abortion, before and during a 3 year follow-up period Hum Reprod 11 1996 117 120
25. P. Saxena, M.M. Misro, S.P. Chaki, K. Chopra, S. Roy, and D. Nandan Is abnormal sperm function an indicator among couples with recurrent pregnancy loss? Fertil Steril 90 2008 1854 1858
26. S.M. Bhattacharya Association of various sperm parameters with unexplained repeated early pregnancy loss-which is most important? Int Urol Nephrol 40 2008 391 395
27. J.A. Hill, A.F. Abbott, and J.A. Politch Sperm morphology and recurrent abortion Fertil Steril 61 1994 776 778
28. D.T. Carrell, L. Liu, C.M. Peterson, K.P. Jones, H.H. Hatasaka, L. Erickson, and et al. Sperm DNA fragmentation is increased in couples with unexplained recurrent pregnancy loss Arch Androl 49 2003 49 55
29. T. Kobayashi, T. Miyazaki, M. Natori, and S. Nozawa Protective role of superoxide dismutase in human sperm motility: superoxide dismutase activity and lipid peroxide in human seminal plasma and spermatozoa Hum Reprod 6 1991 987 991
30. S.M. Bhattacharya Hypo-osmotic swelling test and unexplained repeat early pregnancy loss J Obstet Gynaecol Res 36 2010 119 122
31. J. Bellver, M. Meseguer, L. Muriel, S. GarcI, A. Pellicer, M.A. Barreto, and et al. Y chromosome microdeletions, sperm DNA fragmentation and sperm oxidative stress as causes of recurrent spontaneous abortion of unknown etiology Hum Reprod 25 2010 1713 1721
32. Y. Qiu, L.G. Wang, L.H. Zhang, D.T. Yang, A.D. Zhang, and J.C. Yu Analysis of sperm chromosomal abnormalities and sperm DNA fragmentation in infertile males Chin J Med Genet 25 2008 681 685
33. M.B. Shamsi, S. Venkatesh, M. Tanwar, G. Singh, S. Mukherjee, N. Malhotra, and et al. Comet assay: A prognostic tool for DNA integrity assessment in infertile men opting for assisted reproduction Indian J Med Res 131 2010 675 681
34. C. González-Marín, J. Gosálvez, and R. Roy Types, causes, detection and repair of DNA fragmentation in animal and human sperm cells Int J Mol Sci 13 2012 14026 14052
35. T. Kazerooni, N. Asadi, L. Jadid, and M. Kazerooni Evaluation of sperm's chromatin quality with acridine orange test, chromomycin A3 and aniline blue staining in couples with unexplained recurrent abortion J Assist Reprod Genet 26 2009 591 596
36. C. Roux, C. Tripogney, C. Joanne, and J.L. Bresson Qualité nucléaire du spermatozoide: Tests d'exploration de la chromatine des spermatozoides humains (protéines nucléaires) Gynecol Obstet Fertil 32 2004 792 798
37. A. Ahmadi, and S.C. Ng Fertilizing ability of DNA-damaged spermatozoa J Exp Zool 284 1999 696 704
38. E. Seli, D.K. Gardner, W.B. Schoolcraft, O. Moffatt, and D. Sakkas Extent of nuclear DNA damage in ejaculated spermatozoa impacts on blastocyst development after in vitro fertilization Fertil Steril 82 2004 378 383
39. A. Borini, N. Tarozzi, D. Bizzaro, M.A. Bonu, L. Fava, C. Flamigni, and et al. Sperm DNA fragmentation: paternal effect on early post-implantation embryo development in ART Hum Reprod 21 2006 2876 2881
40. R. Suganuma, R. Yanagimachi, and M.L. Meistrich Decline in fertility of mouse sperm with abnormal chromatin during epididymal passage as revealed by ICSI Hum Reprod 20 2005 3101 3108
41. J. Egozcue, J. Blanco, and F. Vidal Chromosome studies in human sperm nuclei using fluorescence in-situ hybridization (FISH) Hum Reprod Update 3 1997 441 452
42. L.M. Bernardini, M. Costa, C. Bottazzi, L. Gianaroli, M.C. Magli, P.L. Venturini, and et al. Sperm aneuploidy and recurrent pregnancy loss Reprod Biomed Online 9 2004 312 320
43. D.T. Carrell, A.L. Wilcox, L. Lowy, C.M. Peterson, K.P. Jones, L. Erickson, and et al. Elevated sperm chromosome aneuploidy and apoptosis in patients with unexplained recurrent pregnancy loss Obstet Gynecol 101 2003 1229 1235