Elevated sperm chromosome aneuploidy and apoptosis in patients with unexplained recurrent pregnancy loss

Obstetrics and Gynecology

Volumn 101, Issue 6, 2003, Pages 1229-1235

  Carrell, Douglas T ^a   Wilcox, Aaron L ^b   Lowy, Leasa ^b   Peterson, C Matthew ^b   Jones, Kirtly P ^b   Erickson, Lisa ^b   Campbell, Bruce ^b   Branch, D Ware ^b   Hatasaka, Harry H ^b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANEUPLOIDY; APOPTOSIS; ARTICLE; CHROMOSOME; CHROMOSOME 13; CHROMOSOME 18; CHROMOSOME 21; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; EVALUATION; HUMAN; MALE; MORPHOLOGY; POPULATION RESEARCH; PREGNANCY DISORDER; PRIORITY JOURNAL; RECURRENT PREGNANCY LOSS; SPERM; X CHROMOSOME; Y CHROMOSOME;

EID: 0038209030     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0029-7844(03)00339-9     Document Type: Article

References (39)

1. Lee R.M., Silver R.M. Recurrent pregnancy loss Summary and clinical implications . Semin Reprod Med. 18:2000;433-440.
2. Geller P.A., Klier C.M., Neugebauer R. Anxiety disorders following miscarriage. J Clin Psychiatry. 62:2001;432-438.
3. Neugebauer R., Kline J., Shrout P., Skodol A., O'Connor A., Geller P.A., et al. Major depressive disorder in the 6 months after miscarriage. JAMA. 277:1997;383-388.
4. Lanasa M.C., Hogge M.C., Kubik C.J., Ness R.B., Harger J., Nagel T., et al. A novel X chromosome-linked genetic cause of recurrent spontaneous abortion. Am J Obstet Gynecol. 185:2001;563-568.
5. Robinson W.P., Beever C., Brown C.J., Stephenson M.D. Skewed X inactivation and recurrent spontaneous abortion. Semin Reprod Med. 19:2001;175-181.
6. Gopalkkrishnan K., Padwal V., Meherji P.K. Poor quality of sperm as it affects repeated early pregnancy loss. Arch Androl. 45:2000;111-117.
7. Hill J.A., Abbott A.F., Politch J.A. Sperm morphology and recurrent abortion. Fertil Steril. 61:1994;776-778.
8. Hill J.A., Anderson D.J., Polgar K., Abbott A.F., Politch J.A. Seminal white blood cells and recurrent abortion. Hum Reprod. 9:1994;1180-1183.
9. Homonnai Z.T., Paz G.F., Weiss J.N., David M.P. Relation between semen quality and fate of pregnancy Retrospective study on 534 pregnancies . Int J Androl. 3:1980;574-584.
10. Sbracia S., Cozza G., Grasso J.A., Mastrone M., Scarpellini F. Semen parameters and sperm morphology in men in unexplained recurrent spontaneous abortion, before and during a 3 year follow-up period. Hum Reprod. 11:1996;117-120.
11. Rubio C., Gil-Salom M., Simon C., Vidal F., Rodrigo L., Minguez Y., et al. Incidence of sperm chromosomal abnormalities in a risk population Relationship with sperm quality and ICSI outcome . Hum Reprod. 16:2001;2084-2092.
12. Rubio C., Simon C., Blanco V., Vidal F., Minguez Y., Egozcue J., et al. Implications of sperm chromosome abnormalities in recurrent miscarriage. J Assist Reprod Genet. 16:1999;253-258.
13. Carrell D.T., Liu L., Peterson C.M., Jones K.P., Hatasaka H.H., Erickson L., et al. Sperm DNA fragmentation is increased in couples with unexplained recurrent pregnancy loss. Arch Androl. 49:2003;49-55.
14. WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction. 4th ed:1999;Cambridge University Press, Cambridge, UK.
15. Carrell D.T., Emery B., Liu L. Characterization of chromosome aneuploidy rates, decondensation ability, nuclear protamines, and functional ability of round-headed sperm from siblings, and implications for intracytoplasmic sperm injection (ICSI). Fertil Steril. 71:1999;511-516.
16. Shi Q., Martin R.H. Aneuploidy in human spermatozoa FISH analysis in men with constitutional chromosomal abnormalities, and in infertile men . Reproduction. 121:2001;655-666.
17. Pfeffer J., Pang M., Hoegerman S., Osgood C., Stacey M., Mayer J., et al. Aneuploidy frequencies in semen fractions from ten oligoasthenoteratozoospermic patients donating sperm for intracytoplasmic sperm injection. Fertil Steril. 72:1999;472-478.
18. Van Opstal D., Los F.J., Ramlakhan S., Van Hemel J.O., Van Den Ouweland A.M., Brandenburg H., et al. Determination of the parent of origin in nine cases of prenatally detected chromosome aberrations found after intracytoplasmic sperm injection. Hum Reprod. 12:1997;682-686.
19. Carrell D.T., Wilcox A.L., Udoff L.C., Thorp C., Campbell B. Chromosome 15 aneuploidy in the sperm and conceptus of a sibling with variable familial expression of round-headed sperm syndrome. Fertil Steril. 76:2001;1258-1260.
20. Bahce M., Cohen J., Munne S. Preimplantation genetic diagnosis of aneuploidy Were we looking at the wrong chromosomes? J Assist Reprod Genet. 16:1999;176-178.
21. Gorczyca W., Traganos F., Jesionowska H., Darzynkiewicz Z. Presence of DNA strand breaks and increased sensitivity of DNA in situ to denaturation in abnormal human sperm cells Analogy to apoptosis of somatic cells . Exp Cell Res. 207:1993;202-205.
22. Hughes C.M., Lewis S.E., McKelvey-Martin V.J., Thompson W. A comparison of baseline and induced DNA damage in human spermatozoa from fertile and infertile men, using a modified comet assay. Mol Hum Reprod. 2:1996;613-619.
23. Kodama H., Yamaguchi R., Rukuda J., Kasai H., Tanaka T. Increased oxidative deoxyribonucleic acid damage in the spermatozoa of infertile male patients. Fertil Steril. 68:1997;519-524.
24. Shen H., Ong C. Detection of oxidative DNA damage in human sperm and its association with sperm function and male infertility. Free Radic Biol Med. 28:2000;529-536.
25. Zini A., Kamal K., Phang D., Willis J., Jarvi K. Biologic variability of sperm DNA denaturation in infertile men. Urology. 581:2000;258-261.
26. Irvine D.S., Twigg J.P., Gordon E.L., Fulton N., Milne P.A., Aitken R.J. DNA integrity in human spermatozoa Relationships with semen quality . J Androl. 21:2000;33-44.
27. Zini A., Bielexki R., Phang D., Zenzes M.T. Correlations between two markers of sperm DNA integrity, DNA denaturation and DNA fragmentation, in fertile and infertile men. Fertil Steril. 75:2001;674-677.
28. Sun J.G., Jurisicova A., Casper R.F. Detection of deoxyribonucleic acid fragmentation in human sperm Correlation with fertilization in vitro . Biol Reprod. 56:1997;602-607.
29. Eaker S., Pyle A., Cobb J., Handel M.A. Evidence for meiotic spindle checkpoint from analysis of spermatocytes from Robertsonian-chromosome heterozygous mice. J Cell Sci. 114:2001;2953-2965.
30. Handel M.A. The genetics of spermogenesis Meiosis and gamete quality . Robaire B., Chemes H., Morales C.R. Andrology in the 21st Century: Proceedings of the VIIth International Congress of Andrology. 2001;Medimond Publishing Company, Englewood, New Jersey.
31. LeMaire-Adkins R., Radke K., Hunt P.A. Lack of checkpoint control at the metaphase/anaphase transition A mechanism of meiotic nondisjunction in mammalian females . J Cell Biol. 139:1997;1611-1619.
32. De Palma A., Vicari E., Palermo I., D'Agata R., Caolgero A.E. Effects of cancer and anti-neoplastic treatment on the human testicular function. J Endocrinol Invest. 23:2000;690-696.
33. Kallio M., Lahdetie J. Fragmentation of centromeric DNA and prevention of homologous chromosome separation in male mouse meiosis in vivo by the topoisomerase II inhibitor etoposide. Mutagenesis. 11:1996;435-443.
34. Carrell D.T., Peterson C.M., Hatasaka H.H., Jones K.P., Urry R.L. Abnormal sperm morphology affects embryo quality and pregnancy rates during IVF, but not during ICSI. J Assist Reprod Technol Androl. 9:1997;182-192.
35. Check J.H., Katsoff D., Check M.L. Some semen abnormalities may cause infertility by impairing implantation rather than fertilization. Med Hypotheses. 56:2001;633-637.
36. Nagy Z.P., Verheyen G., Tournaye H., Van Steirteghem A.C. Special applications of intracytoplasmic sperm injection The influence of sperm count, motility, morphology, source and sperm antibody on the outcome of ICSI . Hum Reprod. 13:(Suppl 1):1998;143-154.
37. Marvara C.S., Hewitson L.C., Simerly C.R., Sutovsky P., Schatten G. The implications of a paternally derived centrosome during human fertilization Consequences for reproduction and the treatment of male factor infertility . Am J Reprod Immunol. 37:1997;39-49.
38. Brinkworth M.H. Paternal transmission of genetic damage Findings in animals and humans . Int J Androl. 23:2000;123-135.
39. Quenby S., Vince G., Rarquharson R., Aplin J. Recurrent miscarriage A defect in nature's quality control? Hum Reprod. 17:2002;1959-1963.