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Volumn 9, Issue , 2015, Pages 113-121

Galectin-3 as a potential target to prevent cancer metastasis

Author keywords

Angiogenesis; Apoptosis; Galectin 3; TF disaccharide; Tumorigenesis

Indexed keywords

ANTINEOPLASTIC AGENT; BETA1 INTEGRIN; CD7 ANTIGEN; CD98 ANTIGEN; COMPLEMENTARY DNA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DEXAMETHASONE; DOXORUBICIN; FAS ANTIGEN; GALECTIN 3; GAMMA INTERFERON; GCS 100; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MELPHALAN; PROTEIN MCL 1; PROTEIN NOXA; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84948989451     PISSN: 11795549     EISSN: 11795549     Source Type: Journal    
DOI: 10.4137/CMO.S29462     Document Type: Article
Times cited : (100)

References (143)
  • 1
    • 1542285490 scopus 로고    scopus 로고
    • Biochemical and molecular characterization of galectins from zebrafish (Danio rerio): Notochord-specific expression of a prototype galectin during early embryogenesis
    • Ahmed H, Du SJ, O'Leary N, Vasta GR. Biochemical and molecular characterization of galectins from zebrafish (Danio rerio): notochord-specific expression of a prototype galectin during early embryogenesis. Glycobiology. 2004;14:219-32.
    • (2004) Glycobiology. , vol.14 , pp. 219-232
    • Ahmed, H.1    Du, S.J.2    O'Leary, N.3    Vasta, G.R.4
  • 2
    • 36148941318 scopus 로고    scopus 로고
    • Regulation of cancer-related gene expression by galectin-3 and the molecular mechanism of its nuclear import pathway
    • Nakahara S, Raz A. Regulation of cancer-related gene expression by galectin-3 and the molecular mechanism of its nuclear import pathway. Cancer Metastasis Rev. 2007;26:605-10.
    • (2007) Cancer Metastasis Rev. , vol.26 , pp. 605-610
    • Nakahara, S.1    Raz, A.2
  • 3
    • 34447301574 scopus 로고    scopus 로고
    • An emerging role for galectins in tuning the immune response: Lessons from experimental models of inflammatory disease, autoimmunity and cancer
    • Rabinovich GA, Liu FT, Hirashima M, Anderson A. An emerging role for galectins in tuning the immune response: lessons from experimental models of inflammatory disease, autoimmunity and cancer. Scand J Immunol. 2007;66:143-58.
    • (2007) Scand J Immunol. , vol.66 , pp. 143-158
    • Rabinovich, G.A.1    Liu, F.T.2    Hirashima, M.3    Anderson, A.4
  • 4
    • 39549123615 scopus 로고    scopus 로고
    • Biological modulation by lectins and their ligands in tumor progression and metastasis
    • Nakahara S, Raz A. Biological modulation by lectins and their ligands in tumor progression and metastasis. Anticancer Agents Med Chem. 2008;8:22-36.
    • (2008) Anticancer Agents Med Chem. , vol.8 , pp. 22-36
    • Nakahara, S.1    Raz, A.2
  • 5
    • 65649109738 scopus 로고    scopus 로고
    • Roles of galectins in infection
    • Vasta GR. Roles of galectins in infection. Nat Rev Microbiol. 2009;7:424-38.
    • (2009) Nat Rev Microbiol. , vol.7 , pp. 424-438
    • Vasta, G.R.1
  • 6
    • 18044396712 scopus 로고    scopus 로고
    • On the role of galectin-3 in cancer apoptosis
    • Nakahara S, Oka N, Raz A. On the role of galectin-3 in cancer apoptosis. Apoptosis. 2005;10:267-75.
    • (2005) Apoptosis. , vol.10 , pp. 267-275
    • Nakahara, S.1    Oka, N.2    Raz, A.3
  • 8
    • 67649831425 scopus 로고    scopus 로고
    • The regulation of inflammation by galectin-3
    • Henderson NC, Sethi T. The regulation of inflammation by galectin-3. Immunol Rev. 2009;230:160-71.
    • (2009) Immunol Rev. , vol.230 , pp. 160-171
    • Henderson, N.C.1    Sethi, T.2
  • 9
    • 67649795958 scopus 로고    scopus 로고
    • Galectin-3 regulates T-cell functions
    • Hsu DK, Chen HY, Liu FT. Galectin-3 regulates T-cell functions. Immunol Rev. 2009;230:114-27.
    • (2009) Immunol Rev. , vol.230 , pp. 114-127
    • Hsu, D.K.1    Chen, H.Y.2    Liu, F.T.3
  • 10
    • 84894504470 scopus 로고    scopus 로고
    • Intracellular galectins in cancer cells: Potential new targets for therapy
    • Vladoiu MC, Labrie M, St-Pierre Y. Intracellular galectins in cancer cells: potential new targets for therapy. Int J Oncol. 2014;44:1001-14.
    • (2014) Int J Oncol. , vol.44 , pp. 1001-1014
    • Vladoiu, M.C.1    Labrie, M.2    St-Pierre, Y.3
  • 11
    • 0033572093 scopus 로고    scopus 로고
    • 2 terminus of galectin-3 governs cellular compartmentalization and functions in cancer cells
    • 2 terminus of galectin-3 governs cellular compartmentalization and functions in cancer cells. Cancer Res. 1999;59:6239-45.
    • (1999) Cancer Res. , vol.59 , pp. 6239-6245
    • Gong, H.C.1    Honjo, Y.2    Nangia-Makker, P.3
  • 12
    • 0027492711 scopus 로고
    • L-29, an endogenous lectin, binds to glycoconjugate ligands with positive cooperativity
    • Massa SM, Cooper DN, Leffler H, Barondes SH. L-29, an endogenous lectin, binds to glycoconjugate ligands with positive cooperativity. Biochemistry. 1993;32:260-7.
    • (1993) Biochemistry. , vol.32 , pp. 260-267
    • Massa, S.M.1    Cooper, D.N.2    Leffler, H.3    Barondes, S.H.4
  • 13
    • 0036510564 scopus 로고    scopus 로고
    • Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest
    • Yoshii T, Fukumori T, Honjo Y, Inohara H, Kim HR, Raz A. Galectin-3 phosphorylation is required for its anti-apoptotic function and cell cycle arrest. J Biol Chem. 2002;277:6852-7.
    • (2002) J Biol Chem. , vol.277 , pp. 6852-6857
    • Yoshii, T.1    Fukumori, T.2    Honjo, Y.3    Inohara, H.4    Kim, H.R.5    Raz, A.6
  • 14
    • 0032495595 scopus 로고    scopus 로고
    • Modulation of the biological functions of galectin-3 by matrix metalloproteinases
    • Ochieng J, Green B, Evans S, James O, Warfield P. Modulation of the biological functions of galectin-3 by matrix metalloproteinases. Biochim Biophys Acta. 1998;1379:97-106.
    • (1998) Biochim Biophys Acta. , vol.1379 , pp. 97-106
    • Ochieng, J.1    Green, B.2    Evans, S.3    James, O.4    Warfield, P.5
  • 15
    • 0026770786 scopus 로고
    • Biochemical and biophysical characterization of human recombinant IgE-binding protein, an S-type animal lectin
    • Hsu DK, Zuberi RI, Liu FT. Biochemical and biophysical characterization of human recombinant IgE-binding protein, an S-type animal lectin. J Biol Chem. 1992;267:14167-74.
    • (1992) J Biol Chem. , vol.267 , pp. 14167-14174
    • Hsu, D.K.1    Zuberi, R.I.2    Liu, F.T.3
  • 16
    • 0027310193 scopus 로고
    • Structure-function relationship of a recombinant human galactoside-binding protein
    • Ochieng J, Platt D, Tait L. Structure-function relationship of a recombinant human galactoside-binding protein. Biochemistry. 1993;32:4455-60.
    • (1993) Biochemistry. , vol.32 , pp. 4455-4460
    • Ochieng, J.1    Platt, D.2    Tait, L.3
  • 17
    • 0029900083 scopus 로고    scopus 로고
    • Expression of galectin-3 modulates T-cell growth and apoptosis
    • Yang RY, Hsu DK, Liu FT. Expression of galectin-3 modulates T-cell growth and apoptosis. Proc Natl Acad Sci U S A. 1996;93:6737-42.
    • (1996) Proc Natl Acad Sci U S A. , vol.93 , pp. 6737-6742
    • Yang, R.Y.1    Hsu, D.K.2    Liu, F.T.3
  • 18
    • 0000594001 scopus 로고    scopus 로고
    • Role of the carboxyl-terminal lectin domain in self-association of galectin-3
    • Yang RY, Hill PN, Hsu DK, Liu FT. Role of the carboxyl-terminal lectin domain in self-association of galectin-3. Biochemistry. 1998;37:4086-92.
    • (1998) Biochemistry. , vol.37 , pp. 4086-4092
    • Yang, R.Y.1    Hill, P.N.2    Hsu, D.K.3    Liu, F.T.4
  • 19
    • 0031231651 scopus 로고    scopus 로고
    • Mapping of the galectin-3 gene (LGALS3) to human chromosome 14 at region 14q21-22
    • Raimond J, Zimonjic DB, Mignon C, et al. Mapping of the galectin-3 gene (LGALS3) to human chromosome 14 at region 14q21-22. Mamm Genome. 1997;8:706-7.
    • (1997) Mamm Genome. , vol.8 , pp. 706-707
    • Raimond, J.1    Zimonjic, D.B.2    Mignon, C.3
  • 20
    • 0031819671 scopus 로고    scopus 로고
    • The human LGALS3 (galectin-3) gene: Determination of the gene structure and functional characterization of the promoter
    • Kadrofske MM, Openo KP, Wang JL. The human LGALS3 (galectin-3) gene: determination of the gene structure and functional characterization of the promoter. Arch Biochem Biophys. 1998;349:7-20.
    • (1998) Arch Biochem Biophys. , vol.349 , pp. 7-20
    • Kadrofske, M.M.1    Openo, K.P.2    Wang, J.L.3
  • 21
    • 0028904118 scopus 로고
    • The second intron of the human galectin-3 gene has a strong promoter activity down-regulated by p53
    • Raimond J, Rouleux F, Monsigny M, Legrand A. The second intron of the human galectin-3 gene has a strong promoter activity down-regulated by p53. FEBS Lett. 1995;363:165-9.
    • (1995) FEBS Lett. , vol.363 , pp. 165-169
    • Raimond, J.1    Rouleux, F.2    Monsigny, M.3    Legrand, A.4
  • 22
    • 0035951844 scopus 로고    scopus 로고
    • Identification of an internal gene to the human Galectin-3 gene with two different overlapping reading frames that do not encode Galectin-3
    • Guittaut M, Charpentier S, Normand T, Dubois M, Raimond J, Legrand A. Identification of an internal gene to the human Galectin-3 gene with two different overlapping reading frames that do not encode Galectin-3. J Biol Chem. 2001;276:2652-7.
    • (2001) J Biol Chem. , vol.276 , pp. 2652-2657
    • Guittaut, M.1    Charpentier, S.2    Normand, T.3    Dubois, M.4    Raimond, J.5    Legrand, A.6
  • 23
    • 9244224133 scopus 로고    scopus 로고
    • A novel cell death gene that encodes a mitochondrial protein promoting cytochrome c release
    • Duneau M, Boyer-Guittaut M, Gonzalez P, et al. A novel cell death gene that encodes a mitochondrial protein promoting cytochrome c release. Exp Cell Res. 2005;302:194-205.
    • (2005) Exp Cell Res. , vol.302 , pp. 194-205
    • Duneau, M.1    Boyer-Guittaut, M.2    Gonzalez, P.3
  • 24
    • 0032557645 scopus 로고    scopus 로고
    • X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution
    • Seetharaman J, Kanigsberg A, Slaaby R, Leffler H, Barondes SH, Rini JM. X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution. J Biol Chem. 1998;273:13047-52.
    • (1998) J Biol Chem. , vol.273 , pp. 13047-13052
    • Seetharaman, J.1    Kanigsberg, A.2    Slaaby, R.3    Leffler, H.4    Barondes, S.H.5    Rini, J.M.6
  • 25
    • 33947301415 scopus 로고    scopus 로고
    • Slow diffusion of lactose out of galectin-3 crystals monitored by X-ray crystallography: Possible implications for ligand-exchange protocols
    • Collins PM, Hidari KIPJ, Blanchard H. Slow diffusion of lactose out of galectin-3 crystals monitored by X-ray crystallography: possible implications for ligand-exchange protocols. Acta Crystallogr D Biol Crystallogr. 2007;63:415-9.
    • (2007) Acta Crystallogr D Biol Crystallogr. , vol.63 , pp. 415-419
    • Collins, P.M.1    Hidari, K.I.P.J.2    Blanchard, H.3
  • 26
    • 80052949203 scopus 로고    scopus 로고
    • Structural basis for distinct binding properties of the human galectins to Thomsen-Friedenreich antigen
    • Bian CF, Zhang Y, Sun H, Li DF, Wang DC. Structural basis for distinct binding properties of the human galectins to Thomsen-Friedenreich antigen. PLoS One. 2011;6:e25007.
    • (2011) PLoS One. , vol.6
    • Bian, C.F.1    Zhang, Y.2    Sun, H.3    Li, D.F.4    Wang, D.C.5
  • 27
    • 84875499442 scopus 로고    scopus 로고
    • Cod glycopeptide with picomolar affinity to galectin-3 suppresses T-cell apoptosis and prostate cancer metastasis
    • Guha P, Kaptan E, Bandyopadhyaya G, et al. Cod glycopeptide with picomolar affinity to galectin-3 suppresses T-cell apoptosis and prostate cancer metastasis. Proc Natl Acad Sci U S A. 2013;110:5052-7.
    • (2013) Proc Natl Acad Sci U S A. , vol.110 , pp. 5052-5057
    • Guha, P.1    Kaptan, E.2    Bandyopadhyaya, G.3
  • 28
    • 0025321107 scopus 로고
    • Human splenic galaptin: Carbohydrate-binding specificity and characterization of the combining site
    • Ahmed H, Allen HJ, Sharma A, Matta KL. Human splenic galaptin: carbohydrate-binding specificity and characterization of the combining site. Biochemistry. 1990;29:5315-9.
    • (1990) Biochemistry. , vol.29 , pp. 5315-5319
    • Ahmed, H.1    Allen, H.J.2    Sharma, A.3    Matta, K.L.4
  • 29
    • 0027960825 scopus 로고
    • Galectins: Conservation of functionally and structurally relevant amino acid residues defines two types of carbohydrate recognition domains
    • Ahmed H, Vasta GR. Galectins: conservation of functionally and structurally relevant amino acid residues defines two types of carbohydrate recognition domains. Glycobiology. 1994;4:545-8.
    • (1994) Glycobiology. , vol.4 , pp. 545-548
    • Ahmed, H.1    Vasta, G.R.2
  • 30
    • 0030447353 scopus 로고    scopus 로고
    • The primary structure and carbohydrate specificity of a ß-galactosyl-binding lectin from toad (Bufo arenarum Hensel) ovary reveal closer similarities to the mammalian galectin-1 than to the galectin from the clawed frog Xenopus laevis
    • Ahmed H, Pohl J, Fink NE, Strobel F, Vasta GR. The primary structure and carbohydrate specificity of a ß-galactosyl-binding lectin from toad (Bufo arenarum Hensel) ovary reveal closer similarities to the mammalian galectin-1 than to the galectin from the clawed frog Xenopus laevis. J Biol Chem. 1996;271:33083-94.
    • (1996) J Biol Chem. , vol.271 , pp. 33083-33094
    • Ahmed, H.1    Pohl, J.2    Fink, N.E.3    Strobel, F.4    Vasta, G.R.5
  • 31
    • 0029837593 scopus 로고    scopus 로고
    • Galectin-1 from bovine spleen: Biochemical characterization, carbohydrate specificity and tissue-specific isoform profiles
    • Ahmed H, Fink NE, Pohl J, Vasta GR. Galectin-1 from bovine spleen: biochemical characterization, carbohydrate specificity and tissue-specific isoform profiles. J Biochem. 1996;120:1007-19.
    • (1996) J Biochem. , vol.120 , pp. 1007-1019
    • Ahmed, H.1    Fink, N.E.2    Pohl, J.3    Vasta, G.R.4
  • 32
    • 0027958144 scopus 로고
    • Structure of S-lectin, a developmentally regulated vertebrate beta-galactoside binding protein
    • Liao DI, Kapadia G, Ahmed H, Vasta GR, Herzberg O. Structure of S-lectin, a developmentally regulated vertebrate beta-galactoside binding protein. Proc Natl Acad Sci U S A. 1994;91:1428-32.
    • (1994) Proc Natl Acad Sci U S A. , vol.91 , pp. 1428-1432
    • Liao, D.I.1    Kapadia, G.2    Ahmed, H.3    Vasta, G.R.4    Herzberg, O.5
  • 33
    • 0034663733 scopus 로고    scopus 로고
    • A soluble ß-galactosyl-binding lectin (galectin) from toad (Bufo arenarum Hensel) ovary: Crystallographic studies of two protein-sugar complexes
    • Bianchet MA, Ahmed H, Vasta GR, Amzel LM. A soluble ß-galactosyl-binding lectin (galectin) from toad (Bufo arenarum Hensel) ovary: crystallographic studies of two protein-sugar complexes. Proteins. 2000;40:378-88.
    • (2000) Proteins. , vol.40 , pp. 378-388
    • Bianchet, M.A.1    Ahmed, H.2    Vasta, G.R.3    Amzel, L.M.4
  • 34
    • 0027169990 scopus 로고
    • The family of metazoan metal-independent b-galactoside-binding lectins:Structure, function and molecular evolution
    • Hirabayashi J, Kasai K. The family of metazoan metal-independent b-galactoside-binding lectins:structure, function and molecular evolution. Glycobiology. 1993;3:297-304.
    • (1993) Glycobiology. , vol.3 , pp. 297-304
    • Hirabayashi, J.1    Kasai, K.2
  • 35
    • 0025335432 scopus 로고
    • Evidence for export of a muscle lectin from cytosol to extracellular matrix and for a novel secretory mechanism
    • Cooper DNW, Barondes SH. Evidence for export of a muscle lectin from cytosol to extracellular matrix and for a novel secretory mechanism. J Cell Biol. 1990;110:1681-91.
    • (1990) J Cell Biol. , vol.110 , pp. 1681-1691
    • Cooper, D.N.W.1    Barondes, S.H.2
  • 36
    • 0028986607 scopus 로고
    • Galectin-1, a ß-galactoside-binding lectin in Chinese hamster ovary cells, II. Localization and biosynthesis
    • Cho M, Cummings RD. Galectin-1, a ß-galactoside-binding lectin in Chinese hamster ovary cells, II. Localization and biosynthesis. J Biol Chem. 1995;270:5207-12.
    • (1995) J Biol Chem. , vol.270 , pp. 5207-5212
    • Cho, M.1    Cummings, R.D.2
  • 37
    • 0032746713 scopus 로고    scopus 로고
    • Kinetic measurements of binding of galectin 3 to a laminin substratum
    • Barboni EA, Bawumia S, Hughes RC. Kinetic measurements of binding of galectin 3 to a laminin substratum. Glycoconj J. 1999;16:365-73.
    • (1999) Glycoconj J. , vol.16 , pp. 365-373
    • Barboni, E.A.1    Bawumia, S.2    Hughes, R.C.3
  • 38
    • 77449085309 scopus 로고    scopus 로고
    • Bisecting GlcNAc residues on laminin-332 down-regulate galectin-3-dependent keratinocyte motility
    • Kariya Y, Kawamura C, Tabei T, Gu J. Bisecting GlcNAc residues on laminin-332 down-regulate galectin-3-dependent keratinocyte motility. J Biol Chem. 2010;285:3330-40.
    • (2010) J Biol Chem. , vol.285 , pp. 3330-3340
    • Kariya, Y.1    Kawamura, C.2    Tabei, T.3    Gu, J.4
  • 39
    • 0032577178 scopus 로고    scopus 로고
    • Regulation of cellular adhesion to extracellular matrix proteins by galectin-3
    • Ochieng J, Leite-Browning ML, Warfield P. Regulation of cellular adhesion to extracellular matrix proteins by galectin-3. Biochem Biophys Res Commun. 1998;246:788-91.
    • (1998) Biochem Biophys Res Commun. , vol.246 , pp. 788-791
    • Ochieng, J.1    Leite-Browning, M.L.2    Warfield, P.3
  • 40
    • 0345734273 scopus 로고    scopus 로고
    • CD29 and CD7 mediate galectin-3-induced type II T-cell apoptosis
    • Fukumori T, Takenaka Y, Yoshii T, et al. CD29 and CD7 mediate galectin-3-induced type II T-cell apoptosis. Cancer Res. 2003;63:8302-11.
    • (2003) Cancer Res. , vol.63 , pp. 8302-8311
    • Fukumori, T.1    Takenaka, Y.2    Yoshii, T.3
  • 41
    • 0033571388 scopus 로고    scopus 로고
    • Identification of CD66a and CD66b as the major galectin-3 receptor candidates in human neutrophils
    • Feuk-Lagerstedt E, Jordan ET, Leffler H, Dahlgren C, Karlsson A. Identification of CD66a and CD66b as the major galectin-3 receptor candidates in human neutrophils. J Immunol. 1999;163:5592-8.
    • (1999) J Immunol. , vol.163 , pp. 5592-5598
    • Feuk-Lagerstedt, E.1    Jordan, E.T.2    Leffler, H.3    Dahlgren, C.4    Karlsson, A.5
  • 42
    • 0026047293 scopus 로고
    • Mac-2-binding glycoproteins. Putative ligands for a cytosolic beta-galactoside lectin
    • Rosenberg I, Cherayil BJ, Isselbacher KJ, Pillai S. Mac-2-binding glycoproteins. Putative ligands for a cytosolic beta-galactoside lectin. J Biol Chem. 1991;266:18731-6.
    • (1991) J Biol Chem. , vol.266 , pp. 18731-18736
    • Rosenberg, I.1    Cherayil, B.J.2    Isselbacher, K.J.3    Pillai, S.4
  • 43
    • 0035445710 scopus 로고    scopus 로고
    • Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein
    • Park JW, Voss PG, Grabski S, Wang JL, Patterson RJ. Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein. Nucleic Acids Res. 2001;29:3595-602.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 3595-3602
    • Park, J.W.1    Voss, P.G.2    Grabski, S.3    Wang, J.L.4    Patterson, R.J.5
  • 44
    • 2642588125 scopus 로고    scopus 로고
    • Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signaling
    • Liu L, Sakai T, Sano N, Fukui K. Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signaling. Biochem J. 2004;380:31-41.
    • (2004) Biochem J. , vol.380 , pp. 31-41
    • Liu, L.1    Sakai, T.2    Sano, N.3    Fukui, K.4
  • 45
    • 0037013214 scopus 로고    scopus 로고
    • Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation
    • Yu F, Finley RL Jr, Raz A, Kim HR. Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation. J Biol Chem. 2002;277:15819-27.
    • (2002) J Biol Chem. , vol.277 , pp. 15819-15827
    • Yu, F.1    Finley, R.L.2    Raz, A.3    Kim, H.R.4
  • 47
    • 60549098654 scopus 로고    scopus 로고
    • Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity
    • Song S, Mazurek N, Liu C, et al. Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity. Cancer Res. 2009;69:1343-9.
    • (2009) Cancer Res. , vol.69 , pp. 1343-1349
    • Song, S.1    Mazurek, N.2    Liu, C.3
  • 48
    • 0037824662 scopus 로고    scopus 로고
    • Potential roles of galectins in myeloid differentiation into three different lineages
    • Abedin MJ, Kashio Y, Seki M, Nakamura K, Hirashima M. Potential roles of galectins in myeloid differentiation into three different lineages. J Leukoc Biol. 2003;73:650-6.
    • (2003) J Leukoc Biol. , vol.73 , pp. 650-656
    • Abedin, M.J.1    Kashio, Y.2    Seki, M.3    Nakamura, K.4    Hirashima, M.5
  • 49
    • 0025947916 scopus 로고
    • Selective up-regulation of macrophage function in granulocyte-macrophage colony-stimulating factor transgenic mice
    • Elliott MJ, Strasser A, Metcalf D. Selective up-regulation of macrophage function in granulocyte-macrophage colony-stimulating factor transgenic mice. J Immunol. 1991;147:2957-63.
    • (1991) J Immunol. , vol.147 , pp. 2957-2963
    • Elliott, M.J.1    Strasser, A.2    Metcalf, D.3
  • 50
    • 0032763663 scopus 로고    scopus 로고
    • Galectin-3/MAC-2 in experimental allergic encephalomyelitis
    • Reichert F, Rotshenker S. Galectin-3/MAC-2 in experimental allergic encephalomyelitis. Exp Neurol. 1999;160:508-14.
    • (1999) Exp Neurol. , vol.160 , pp. 508-514
    • Reichert, F.1    Rotshenker, S.2
  • 51
    • 0028874589 scopus 로고
    • Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages
    • Liu FT, Hsu DK, Zuberi RI, Kuwabara I, Chi EY, Henderson WR Jr. Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages. Am J Pathol. 1995;147:1016-28.
    • (1995) Am J Pathol. , vol.147 , pp. 1016-1028
    • Liu, F.T.1    Hsu, D.K.2    Zuberi, R.I.3    Kuwabara, I.4    Chi, E.Y.5    Henderson, W.R.6
  • 52
    • 27344447124 scopus 로고    scopus 로고
    • Effects of aspirin and indomethacin on galectin-3
    • Dabelic S, Flogel M, Dumic J. Effects of aspirin and indomethacin on galectin-3. Croat Chem Acta. 2005;178:433-40.
    • (2005) Croat Chem Acta. , vol.178 , pp. 433-440
    • Dabelic, S.1    Flogel, M.2    Dumic, J.3
  • 53
    • 22144460572 scopus 로고    scopus 로고
    • Corticosteroids affect galectin-3 expression
    • Dabelic S, Flogel M, Dumic J. Corticosteroids affect galectin-3 expression. Period Biol. 2005;107:175-81.
    • (2005) Period Biol. , vol.107 , pp. 175-181
    • Dabelic, S.1    Flogel, M.2    Dumic, J.3
  • 56
    • 0028095353 scopus 로고
    • Galectin-3 mRNA level depends on transformation phenotype in ras-transformed NIH 3T3 cells
    • Hebert E, Monsigny M. Galectin-3 mRNA level depends on transformation phenotype in ras-transformed NIH 3T3 cells. Biol Cell. 1994;81:73-6.
    • (1994) Biol Cell. , vol.81 , pp. 73-76
    • Hebert, E.1    Monsigny, M.2
  • 58
    • 0030003692 scopus 로고    scopus 로고
    • Human T lymphotropic virus-I infection of human T lymphocytes induces expression of the beta-galactoside-binding lectin, galectin-3
    • Hsu DK, Hammes SR, Kuwabara I, Greene WC, Liu FT. Human T lymphotropic virus-I infection of human T lymphocytes induces expression of the beta-galactoside-binding lectin, galectin-3. Am J Pathol. 1996;148:1661-70.
    • (1996) Am J Pathol. , vol.148 , pp. 1661-1670
    • Hsu, D.K.1    Hammes, S.R.2    Kuwabara, I.3    Greene, W.C.4    Liu, F.T.5
  • 59
    • 0033655187 scopus 로고    scopus 로고
    • Expression of galectin-3 in cells exposed to stress-Roles of jun and NF-kappaB
    • Dumic J, Lauc G, Flogel M. Expression of galectin-3 in cells exposed to stress-Roles of jun and NF-kappaB. Cell Physiol Biochem. 2000;10:149-58.
    • (2000) Cell Physiol Biochem. , vol.10 , pp. 149-158
    • Dumic, J.1    Lauc, G.2    Flogel, M.3
  • 61
    • 15544386594 scopus 로고    scopus 로고
    • Extracellular nucleotides activate Runx2 in the osteoblast-like HOBIT cell line: A possible molecular link between mechanical stress and osteoblasts' response
    • Costessi A, Pines A, D'Andrea P, et al. Extracellular nucleotides activate Runx2 in the osteoblast-like HOBIT cell line: a possible molecular link between mechanical stress and osteoblasts' response. Bone. 2005;36:418-32.
    • (2005) Bone. , vol.36 , pp. 418-432
    • Costessi, A.1    Pines, A.2    D'Andrea, P.3
  • 62
    • 34248202726 scopus 로고    scopus 로고
    • Differential expression of galectins in normal, benign and malignant prostate epithelial cells: Silencing of galectin-3 expression in prostate cancer by its promoter methylation
    • Ahmed H, Banerjee PB, Vasta GR. Differential expression of galectins in normal, benign and malignant prostate epithelial cells: silencing of galectin-3 expression in prostate cancer by its promoter methylation. Biochem Biophys Res Commun. 2007;358:241-6.
    • (2007) Biochem Biophys Res Commun. , vol.358 , pp. 241-246
    • Ahmed, H.1    Banerjee, P.B.2    Vasta, G.R.3
  • 63
    • 13944260094 scopus 로고    scopus 로고
    • Effects of DNA methylation on galectin-3 expression in pituitary tumors
    • Ruebel KH, Jin L, Qian X, et al. Effects of DNA methylation on galectin-3 expression in pituitary tumors. Cancer Res. 2005;65:1136-40.
    • (2005) Cancer Res. , vol.65 , pp. 1136-1140
    • Ruebel, K.H.1    Jin, L.2    Qian, X.3
  • 64
    • 77951939167 scopus 로고    scopus 로고
    • Evidence of heavy methylation in the galectin-3 promoter in early stages of prostate adenocarcinoma: Development and validation of a methylated marker for early diagnosis of prostate cancer
    • Ahmed H, Cappello F, Rodolico V, Vasta GR. Evidence of heavy methylation in the galectin-3 promoter in early stages of prostate adenocarcinoma: development and validation of a methylated marker for early diagnosis of prostate cancer. Transl Oncol. 2009;2:146-56.
    • (2009) Transl Oncol. , vol.2 , pp. 146-156
    • Ahmed, H.1    Cappello, F.2    Rodolico, V.3    Vasta, G.R.4
  • 65
    • 79957467023 scopus 로고    scopus 로고
    • Promoter methylation in prostate cancer and its application for the early detection of prostate cancer using serum and urine samples
    • Ahmed H. Promoter methylation in prostate cancer and its application for the early detection of prostate cancer using serum and urine samples. Biomark Cancer. 2010;2:17-33.
    • (2010) Biomark Cancer. , vol.2 , pp. 17-33
    • Ahmed, H.1
  • 67
    • 0030707480 scopus 로고    scopus 로고
    • Galectin-3: A novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family
    • Akahani S, Nangia-Makker P, Inohara H, Kim HR, Raz A. Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family. Cancer Res. 1997;57:5272-6.
    • (1997) Cancer Res. , vol.57 , pp. 5272-5276
    • Akahani, S.1    Nangia-Makker, P.2    Inohara, H.3    Kim, H.R.4    Raz, A.5
  • 68
    • 2442684458 scopus 로고    scopus 로고
    • Endogenous galectin-3 determines the routing of CD95 apoptotic signaling pathways
    • Fukumori T, Takenaka Y, Oka N, et al. Endogenous galectin-3 determines the routing of CD95 apoptotic signaling pathways. Cancer Res. 2004;64:3376-9.
    • (2004) Cancer Res. , vol.64 , pp. 3376-3379
    • Fukumori, T.1    Takenaka, Y.2    Oka, N.3
  • 69
    • 4544295231 scopus 로고    scopus 로고
    • Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity
    • Elad-Sfadia G, Haklai R, Balan E, Kloog Y. Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity. J Biol Chem. 2004;279:34922-30.
    • (2004) J Biol Chem. , vol.279 , pp. 34922-34930
    • Elad-Sfadia, G.1    Haklai, R.2    Balan, E.3    Kloog, Y.4
  • 71
    • 0038842637 scopus 로고    scopus 로고
    • Roles of galectins in vivo
    • Poirier F. Roles of galectins in vivo. Biochem Soc Symp. 2002;69:95-103.
    • (2002) Biochem Soc Symp. , vol.69 , pp. 95-103
    • Poirier, F.1
  • 72
    • 62649166487 scopus 로고    scopus 로고
    • Duodenal intraepithelial lymphocytes of children with cow milk allergy preferentially bind the glycan-binding protein galectin-3
    • Mercer N, Guzman L, Cueto Rua E, et al. Duodenal intraepithelial lymphocytes of children with cow milk allergy preferentially bind the glycan-binding protein galectin-3. Int J Immunopathol Pharmacol. 2009;22:207-17.
    • (2009) Int J Immunopathol Pharmacol. , vol.22 , pp. 207-217
    • Mercer, N.1    Guzman, L.2    Cueto Rua, E.3
  • 73
    • 48749097847 scopus 로고    scopus 로고
    • Expression of galectin-3 in the tumor immune response in colon cancer
    • Dumont P, Berton A, Nagy N, et al. Expression of galectin-3 in the tumor immune response in colon cancer. Lab Invest. 2008;88:896-906.
    • (2008) Lab Invest. , vol.88 , pp. 896-906
    • Dumont, P.1    Berton, A.2    Nagy, N.3
  • 74
    • 0036830153 scopus 로고    scopus 로고
    • Galectins-3 and -7, but not galectin-1, play a role in re-epithelialization of wounds
    • Cao Z, Said N, Amin S, et al. Galectins-3 and -7, but not galectin-1, play a role in re-epithelialization of wounds. J Biol Chem. 2002;277:42299-305.
    • (2002) J Biol Chem. , vol.277 , pp. 42299-42305
    • Cao, Z.1    Said, N.2    Amin, S.3
  • 75
    • 0037311060 scopus 로고    scopus 로고
    • Expression and function of receptors for advanced glycation end products in bovine corneal endothelial cells
    • Kaji Y, Amano S, Usui T, et al. Expression and function of receptors for advanced glycation end products in bovine corneal endothelial cells. Invest Ophthalmol Vis Sci. 2003;44:521-9.
    • (2003) Invest Ophthalmol Vis Sci. , vol.44 , pp. 521-529
    • Kaji, Y.1    Amano, S.2    Usui, T.3
  • 76
    • 62749106846 scopus 로고    scopus 로고
    • Renal expression of galectin-3 in systemic lupus erythematosus patients with nephritis
    • Kang EH, Moon KC, Lee EY, et al. Renal expression of galectin-3 in systemic lupus erythematosus patients with nephritis. Lupus. 2009;18:22-8.
    • (2009) Lupus. , vol.18 , pp. 22-28
    • Kang, E.H.1    Moon, K.C.2    Lee, E.Y.3
  • 77
    • 34248154715 scopus 로고    scopus 로고
    • Upregulation of galectin-3 by Corynebacterium kutscheri infection in the rat lung
    • Won YS, Jeong ES, Park HJ, et al. Upregulation of galectin-3 by Corynebacterium kutscheri infection in the rat lung. Exp Anim. 2007;56:85-91.
    • (2007) Exp Anim. , vol.56 , pp. 85-91
    • Won, Y.S.1    Jeong, E.S.2    Park, H.J.3
  • 78
    • 33947190764 scopus 로고    scopus 로고
    • Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection
    • Silva-Monteiro E, Reis Lorenzato L, Kenji Nihei O, et al. Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection. Am J Pathol. 2007;170:546-56.
    • (2007) Am J Pathol. , vol.170 , pp. 546-556
    • Silva-Monteiro, E.1    Reis Lorenzato, L.2    Kenji Nihei, O.3
  • 79
    • 9644269159 scopus 로고    scopus 로고
    • Alterations in galectin-3 expression and distribution correlate with breast cancer progression: Functional analysis of galectin-3 in breast epithelial-endothelial interactions
    • Shekhar MP, Nangia-Makker P, Tait L, Miller F, Raz A. Alterations in galectin-3 expression and distribution correlate with breast cancer progression: functional analysis of galectin-3 in breast epithelial-endothelial interactions. Am J Pathol. 2004;165:1931-41.
    • (2004) Am J Pathol. , vol.165 , pp. 1931-1941
    • Shekhar, M.P.1    Nangia-Makker, P.2    Tait, L.3    Miller, F.4    Raz, A.5
  • 80
    • 0034235223 scopus 로고    scopus 로고
    • Decreased galectin-3 expression in prostate cancer
    • Pacis RA, Pilat MJ, Pienta KJ, et al. Decreased galectin-3 expression in prostate cancer. Prostate. 2000;44:118-23.
    • (2000) Prostate. , vol.44 , pp. 118-123
    • Pacis, R.A.1    Pilat, M.J.2    Pienta, K.J.3
  • 81
    • 0034243737 scopus 로고    scopus 로고
    • Differential expression of galectin-1 and galectin-3 in benign and malignant salivary gland neoplasms
    • Xu XC, Sola Gallego JJ, Lotan R, El-Naggar AK. Differential expression of galectin-1 and galectin-3 in benign and malignant salivary gland neoplasms. Int J Oncol. 2000;17:271-6.
    • (2000) Int J Oncol. , vol.17 , pp. 271-276
    • Xu, X.C.1    Sola Gallego, J.J.2    Lotan, R.3    El-Naggar, A.K.4
  • 82
    • 0033870239 scopus 로고    scopus 로고
    • Galectin-1 and galectin-3 in chronic pancreatitis
    • Wang L, Friess H, Zhu Z, et al. Galectin-1 and galectin-3 in chronic pancreatitis. Lab Invest. 2000;80:1233-41.
    • (2000) Lab Invest. , vol.80 , pp. 1233-1241
    • Wang, L.1    Friess, H.2    Zhu, Z.3
  • 83
    • 0033020722 scopus 로고    scopus 로고
    • Galectin-3 modulates rat mesangial cell proliferation and matrix synthesis during experimental glomerulonephritis induced by anti-Thy1.1 antibodies
    • Sasaki S, Bao Q, Hughes RC. Galectin-3 modulates rat mesangial cell proliferation and matrix synthesis during experimental glomerulonephritis induced by anti-Thy1.1 antibodies. J Pathol. 1999;187:481-9.
    • (1999) J Pathol. , vol.187 , pp. 481-489
    • Sasaki, S.1    Bao, Q.2    Hughes, R.C.3
  • 84
    • 0038434098 scopus 로고    scopus 로고
    • Carbohydrate binding proteins galectin-1 and galectin-3 in human trabecular meshwork
    • Fautsch MP, Silva AO, Johnson DH. Carbohydrate binding proteins galectin-1 and galectin-3 in human trabecular meshwork. Exp Eye Res. 2003;77:11-6.
    • (2003) Exp Eye Res. , vol.77 , pp. 11-16
    • Fautsch, M.P.1    Silva, A.O.2    Johnson, D.H.3
  • 85
    • 0035085638 scopus 로고    scopus 로고
    • Expression of endogenous galectin-1 and galectin-3 in intrahepatic cholangiocarcinoma
    • Shimonishi T, Miyazaki K, Kono N, et al. Expression of endogenous galectin-1 and galectin-3 in intrahepatic cholangiocarcinoma. Hum Pathol. 2001;32:302-10.
    • (2001) Hum Pathol. , vol.32 , pp. 302-310
    • Shimonishi, T.1    Miyazaki, K.2    Kono, N.3
  • 86
    • 0023406938 scopus 로고
    • Endogenous lectins from cultured cells: Nuclear localization of carbohydrate-binding protein 35 in proliferating 3T3 fibroblasts
    • Moutsatsos IK, Wade M, Schindler M, Wang JL. Endogenous lectins from cultured cells: nuclear localization of carbohydrate-binding protein 35 in proliferating 3T3 fibroblasts. Proc Natl Acad Sci U S A. 1987;84:6452-6.
    • (1987) Proc Natl Acad Sci U S A. , vol.84 , pp. 6452-6456
    • Moutsatsos, I.K.1    Wade, M.2    Schindler, M.3    Wang, J.L.4
  • 87
    • 0028237331 scopus 로고
    • Expression of Mac-2 antigen in the preosteoclast and osteoclast identified in the op/op mouse injected with macrophage colony-stimulating factor
    • Niida S, Amizuka N, Hara F, Ozawa H, Kodama H. Expression of Mac-2 antigen in the preosteoclast and osteoclast identified in the op/op mouse injected with macrophage colony-stimulating factor. J Bone Miner Res. 1994;9:873-81.
    • (1994) J Bone Miner Res. , vol.9 , pp. 873-881
    • Niida, S.1    Amizuka, N.2    Hara, F.3    Ozawa, H.4    Kodama, H.5
  • 88
    • 0027268374 scopus 로고
    • Human keratinocytes release the endogenous beta-galactoside-binding soluble lectin immunoglobulin E (IgE-binding protein) which binds to Langerhans cells where it modulates their binding capacity for IgE glycoforms
    • Wollenberg A, de la Salle H, Hanau D, Liu FT, Bieber T. Human keratinocytes release the endogenous beta-galactoside-binding soluble lectin immunoglobulin E (IgE-binding protein) which binds to Langerhans cells where it modulates their binding capacity for IgE glycoforms. J Exp Med. 1993;178:777-85.
    • (1993) J Exp Med. , vol.178 , pp. 777-785
    • Wollenberg, A.1    de la Salle, H.2    Hanau, D.3    Liu, F.T.4    Bieber, T.5
  • 89
    • 0028334842 scopus 로고
    • Peripheral nerve injury induces Schwann cells to express two macrophage phenotypes: Phagocytosis and the galactose-specific lectin MAC-2
    • Reichert F, Saada A, Rotshenker S. Peripheral nerve injury induces Schwann cells to express two macrophage phenotypes: phagocytosis and the galactose-specific lectin MAC-2. J Neurosci. 1994;14:3231-45.
    • (1994) J Neurosci. , vol.14 , pp. 3231-3245
    • Reichert, F.1    Saada, A.2    Rotshenker, S.3
  • 90
    • 0028347443 scopus 로고
    • Expression of a 31-kDa lactoside-binding lectin in normal human gastric mucosa and in primary and metastatic gastric carcinomas
    • Lotan R, Ito H, Yasui W, Yokozaki H, Lotan D, Tahara E. Expression of a 31-kDa lactoside-binding lectin in normal human gastric mucosa and in primary and metastatic gastric carcinomas. Int J Cancer. 1994;56:474-80.
    • (1994) Int J Cancer. , vol.56 , pp. 474-480
    • Lotan, R.1    Ito, H.2    Yasui, W.3    Yokozaki, H.4    Lotan, D.5    Tahara, E.6
  • 91
    • 0028097127 scopus 로고
    • Expression of galectins on microvessel endothelial cells and their involvement in tumour cell adhesion
    • Lotan R, Belloni PN, Tressler RJ, Lotan D, Xu XC, Nicolson GL. Expression of galectins on microvessel endothelial cells and their involvement in tumour cell adhesion. Glycoconj J. 1994;11:462-8.
    • (1994) Glycoconj J. , vol.11 , pp. 462-468
    • Lotan, R.1    Belloni, P.N.2    Tressler, R.J.3    Lotan, D.4    Xu, X.C.5    Nicolson, G.L.6
  • 92
    • 0027397170 scopus 로고
    • Human neutrophils express immunoglobulin E (IgE)-binding proteins (Mac-2/epsilon BP) of the S-type lectin family: Role in IgE dependent activation
    • Truong MJ, Gruart V, Kusnierz JP, et al. Human neutrophils express immunoglobulin E (IgE)-binding proteins (Mac-2/epsilon BP) of the S-type lectin family: role in IgE dependent activation. J Exp Med. 1993;177:243-8.
    • (1993) J Exp Med. , vol.177 , pp. 243-248
    • Truong, M.J.1    Gruart, V.2    Kusnierz, J.P.3
  • 93
    • 0027428397 scopus 로고
    • IgE binding molecules (Mac-2/epsilon BP) expressed by human eosinophils. Implication in IgE-dependent eosinophil cytotoxicity
    • Truong MJ, Gruart V, Liu FT, Prin L, Capron A, Capron M. IgE binding molecules (Mac-2/epsilon BP) expressed by human eosinophils. Implication in IgE-dependent eosinophil cytotoxicity. Eur J Immunol. 1993;23:3230-5.
    • (1993) Eur J Immunol. , vol.23 , pp. 3230-3235
    • Truong, M.J.1    Gruart, V.2    Liu, F.T.3    Prin, L.4    Capron, A.5    Capron, M.6
  • 94
    • 0029078421 scopus 로고
    • Immunoelectron microscopic localization of galectin-3, an IgE binding protein, in human mast cells and basophils
    • Craig SS, Krishnaswamy P, Irani AM, Kepley CL, Liu FT, Schwartz LB. Immunoelectron microscopic localization of galectin-3, an IgE binding protein, in human mast cells and basophils. Anat Rec. 1995;242:211-9.
    • (1995) Anat Rec. , vol.242 , pp. 211-219
    • Craig, S.S.1    Krishnaswamy, P.2    Irani, A.M.3    Kepley, C.L.4    Liu, F.T.5    Schwartz, L.B.6
  • 95
    • 0345363290 scopus 로고    scopus 로고
    • Coexpression of binding sites for A (B) histo-blood group trisaccharides with galectin-3 and Lag antigen in human Langerhans cells
    • Smetana K, Holíková Z, Klubal R, et al. Coexpression of binding sites for A (B) histo-blood group trisaccharides with galectin-3 and Lag antigen in human Langerhans cells. J Leukoc Biol. 1999;66:644-9.
    • (1999) J Leukoc Biol. , vol.66 , pp. 644-649
    • Smetana, K.1    Holíková, Z.2    Klubal, R.3
  • 97
    • 0029929404 scopus 로고    scopus 로고
    • Granulocyte macrophage colony stimulating factor produced in lesioned peripheral nerves induces the upregulation of cell surface expression of MAC-2 by macrophages and Schwann cells
    • Saada A, Reichert F, Rotshenker S. Granulocyte macrophage colony stimulating factor produced in lesioned peripheral nerves induces the upregulation of cell surface expression of MAC-2 by macrophages and Schwann cells. J Cell Biol. 1996;133:159-67.
    • (1996) J Cell Biol. , vol.133 , pp. 159-167
    • Saada, A.1    Reichert, F.2    Rotshenker, S.3
  • 98
    • 11144241063 scopus 로고    scopus 로고
    • Galectins as modulators of tumour progression
    • Liu FT, Rabinovich GA. Galectins as modulators of tumour progression. Nat Rev Cancer. 2005;5:29-41.
    • (2005) Nat Rev Cancer. , vol.5 , pp. 29-41
    • Liu, F.T.1    Rabinovich, G.A.2
  • 99
    • 84900468131 scopus 로고    scopus 로고
    • Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic acetylcholine receptor and STAT3
    • Guha P, Bandyopadhyaya G, Polumuri SK, et al. Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic acetylcholine receptor and STAT3. Breast Cancer Res Treat. 2014;145:5-22.
    • (2014) Breast Cancer Res Treat. , vol.145 , pp. 5-22
    • Guha, P.1    Bandyopadhyaya, G.2    Polumuri, S.K.3
  • 100
    • 0030872450 scopus 로고    scopus 로고
    • Expression of the endogenous galactose-binding protein galectin-3 correlates with the malignant potential of tumors in the central nervous system
    • Bresalier RS, Yan PS, Byrd JC, Lotan R, Raz A. Expression of the endogenous galactose-binding protein galectin-3 correlates with the malignant potential of tumors in the central nervous system. Cancer. 1997;80:776-87.
    • (1997) Cancer. , vol.80 , pp. 776-787
    • Bresalier, R.S.1    Yan, P.S.2    Byrd, J.C.3    Lotan, R.4    Raz, A.5
  • 101
  • 102
    • 0036835054 scopus 로고    scopus 로고
    • Increased expression of galectin-3 in primary gastric cancer and the metastatic lymph nodes
    • Miyazaki J, Hokari R, Kato S, et al. Increased expression of galectin-3 in primary gastric cancer and the metastatic lymph nodes. Oncol Rep. 2002;9:1307-12.
    • (2002) Oncol Rep. , vol.9 , pp. 1307-1312
    • Miyazaki, J.1    Hokari, R.2    Kato, S.3
  • 103
    • 0037732931 scopus 로고    scopus 로고
    • Increased expression of the LGALS3 (galectin 3) gene in human non-small-cell lung cancer
    • Yoshimura A, Gemma A, Hosoya Y, et al. Increased expression of the LGALS3 (galectin 3) gene in human non-small-cell lung cancer. Genes Chromosomes Cancer. 2003;37:59-64.
    • (2003) Genes Chromosomes Cancer. , vol.37 , pp. 59-64
    • Yoshimura, A.1    Gemma, A.2    Hosoya, Y.3
  • 104
    • 37449015117 scopus 로고    scopus 로고
    • Involvement of decreased galectin-3 expression in the pathogenesis and progression of prostate cancer
    • Merseburger AS, Kramer MW, Hennenlotter J, et al. Involvement of decreased galectin-3 expression in the pathogenesis and progression of prostate cancer. Prostate. 2008;68:72-7.
    • (2008) Prostate. , vol.68 , pp. 72-77
    • Merseburger, A.S.1    Kramer, M.W.2    Hennenlotter, J.3
  • 105
    • 56449127154 scopus 로고    scopus 로고
    • Loss of galectin-3 expression correlates with clear cell renal carcinoma progression and reduced survival
    • Merseburger AS, Kramer MW, Hennenlotter J, et al. Loss of galectin-3 expression correlates with clear cell renal carcinoma progression and reduced survival. World J Urol. 2008;26:637-42.
    • (2008) World J Urol. , vol.26 , pp. 637-642
    • Merseburger, A.S.1    Kramer, M.W.2    Hennenlotter, J.3
  • 106
    • 0343962593 scopus 로고    scopus 로고
    • Alteration of the cytoplasmic/nuclear expression pattern of galectin-3 correlates with prostate carcinoma progression
    • van den Brûle FA, Waltregny D, Liu FT, Castronovo V. Alteration of the cytoplasmic/nuclear expression pattern of galectin-3 correlates with prostate carcinoma progression. Int J Cancer. 2000;89:361-7.
    • (2000) Int J Cancer. , vol.89 , pp. 361-367
    • van den Brûle, F.A.1    Waltregny, D.2    Liu, F.T.3    Castronovo, V.4
  • 107
    • 2942591023 scopus 로고    scopus 로고
    • Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs
    • Takenaka Y, Fukumori T, Yoshii T, et al. Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs. Mol Cell Biol. 2004;24:4395-406.
    • (2004) Mol Cell Biol. , vol.24 , pp. 4395-4406
    • Takenaka, Y.1    Fukumori, T.2    Yoshii, T.3
  • 108
    • 18244414247 scopus 로고    scopus 로고
    • Galectin-3 as a multifunctional protein
    • Krzeslak A, Lipinska A. Galectin-3 as a multifunctional protein. Cell Mol Biol Lett. 2004;9(2):305-28.
    • (2004) Cell Mol Biol Lett. , vol.9 , Issue.2 , pp. 305-328
    • Krzeslak, A.1    Lipinska, A.2
  • 110
    • 84882724331 scopus 로고    scopus 로고
    • The significance of galectin-3 as a new basal cell marker in prostate cancer
    • Wang Y, Balan V, Gao X, et al. The significance of galectin-3 as a new basal cell marker in prostate cancer. Cell Death Dis. 2013;4:e753.
    • (2013) Cell Death Dis. , vol.4
    • Wang, Y.1    Balan, V.2    Gao, X.3
  • 111
    • 84924719480 scopus 로고    scopus 로고
    • Serum galectin-3 as a potential marker for gastric cancer
    • Cheng D, Liang B, Li Y. Serum galectin-3 as a potential marker for gastric cancer. Med Sci Monit. 2015;21:755-60.
    • (2015) Med Sci Monit. , vol.21 , pp. 755-760
    • Cheng, D.1    Liang, B.2    Li, Y.3
  • 112
    • 6344261571 scopus 로고    scopus 로고
    • Dual activities of galectin-3 in human prostate cancer: Tumor suppression of nuclear galectin-3 vs tumor promotion of cytoplasmic galectin-3
    • Califice S, Castronovo V, Bracke M, van den Brûle F. Dual activities of galectin-3 in human prostate cancer: tumor suppression of nuclear galectin-3 vs tumor promotion of cytoplasmic galectin-3. Oncogene. 2004;23:7527-36.
    • (2004) Oncogene. , vol.23 , pp. 7527-7536
    • Califice, S.1    Castronovo, V.2    Bracke, M.3    van den Brûle, F.4
  • 113
    • 84857048734 scopus 로고    scopus 로고
    • Cell-surface galectin-3 confers resistance to TRAIL by impeding trafficking of death receptors in metastatic colon adenocarcinoma cells
    • Mazurek N, Byrd JC, Sun Y, et al. Cell-surface galectin-3 confers resistance to TRAIL by impeding trafficking of death receptors in metastatic colon adenocarcinoma cells. Cell Death Differ. 2012;19:523-33.
    • (2012) Cell Death Differ. , vol.19 , pp. 523-533
    • Mazurek, N.1    Byrd, J.C.2    Sun, Y.3
  • 114
    • 79955522603 scopus 로고    scopus 로고
    • Transient silencing of galectin-3 expression promotes both in vitro and in vivo drug induced apoptosis of human pancreatic carcinoma cells
    • Kobayashi T, Shimura T, Yajima T, et al. Transient silencing of galectin-3 expression promotes both in vitro and in vivo drug induced apoptosis of human pancreatic carcinoma cells. Clin Exp Metastasis. 2011;28:367-76.
    • (2011) Clin Exp Metastasis. , vol.28 , pp. 367-376
    • Kobayashi, T.1    Shimura, T.2    Yajima, T.3
  • 115
    • 40249108889 scopus 로고    scopus 로고
    • Cell surface N-glycosylation and sialylation regulate galectin-3-induced apoptosis in human diffuse large B cell lymphoma
    • Suzuki O, Abe M. Cell surface N-glycosylation and sialylation regulate galectin-3-induced apoptosis in human diffuse large B cell lymphoma. Oncol Rep. 2008;19:743-8.
    • (2008) Oncol Rep. , vol.19 , pp. 743-748
    • Suzuki, O.1    Abe, M.2
  • 116
    • 84880028368 scopus 로고    scopus 로고
    • Targeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancer
    • Vaillant F, Merino D, Lee L, et al. Targeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancer. Cancer Cell. 2013;24:120-9.
    • (2013) Cancer Cell. , vol.24 , pp. 120-129
    • Vaillant, F.1    Merino, D.2    Lee, L.3
  • 117
    • 84923370451 scopus 로고    scopus 로고
    • Small-molecule Bax agonists for cancer therapy
    • Xin M, Li R, Xie M, et al. Small-molecule Bax agonists for cancer therapy. Nat Commun. 2014;5:4935.
    • (2014) Nat Commun. , vol.5 , pp. 4935
    • Xin, M.1    Li, R.2    Xie, M.3
  • 118
    • 84930573524 scopus 로고    scopus 로고
    • Small-molecule Bcl2 BH4 antagonist for lung cancer therapy
    • Han B, Park D, Li R, et al. Small-molecule Bcl2 BH4 antagonist for lung cancer therapy. Cancer Cell. 2015;27:852-63.
    • (2015) Cancer Cell. , vol.27 , pp. 852-863
    • Han, B.1    Park, D.2    Li, R.3
  • 119
    • 77249139966 scopus 로고    scopus 로고
    • CD133(+) human pulmonary adenocarcinoma cells induce apoptosis of CD8(+) T cells by highly expressed galectin-3
    • Li W, Jian-jun W, Xue-Feng Z, Feng Z. CD133(+) human pulmonary adenocarcinoma cells induce apoptosis of CD8(+) T cells by highly expressed galectin-3. Clin Invest Med. 2010;33:E44-53.
    • (2010) Clin Invest Med. , vol.33 , pp. E44-E53
    • Li, W.1    Jian-Jun, W.2    Xue-Feng, Z.3    Feng, Z.4
  • 120
    • 58649086718 scopus 로고    scopus 로고
    • Regulation of tumor progression by extracellular galectin-3
    • Nangia-Makker P, Balan V, Raz A. Regulation of tumor progression by extracellular galectin-3. Cancer Microenviron. 2008;1:43-51.
    • (2008) Cancer Microenviron. , vol.1 , pp. 43-51
    • Nangia-Makker, P.1    Balan, V.2    Raz, A.3
  • 121
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A, Dixit VM. Death receptors: signaling and modulation. Science. 1998;281:1305-8.
    • (1998) Science. , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 123
    • 0032536771 scopus 로고    scopus 로고
    • Two CD95 (APO-1/Fas) signaling pathways
    • Scaffidi C, Fulda S, Srinivasan A, et al. Two CD95 (APO-1/Fas) signaling pathways. EMBO J. 1998;17:1675-87.
    • (1998) EMBO J. , vol.17 , pp. 1675-1687
    • Scaffidi, C.1    Fulda, S.2    Srinivasan, A.3
  • 124
  • 125
    • 84904610688 scopus 로고    scopus 로고
    • Galectin-3 disruption impaired tumoral angiogenesis by reducing VEGF secretion from TGFβ1-induced macrophages
    • Machado CM, Andrade LN, Teixeira VR, et al. Galectin-3 disruption impaired tumoral angiogenesis by reducing VEGF secretion from TGFβ1-induced macrophages. Cancer Med. 2014;3:201-14.
    • (2014) Cancer Med. , vol.3 , pp. 201-214
    • Machado, C.M.1    Andrade, L.N.2    Teixeira, V.R.3
  • 126
    • 0029759376 scopus 로고    scopus 로고
    • Interactions between galectin-3 and Mac-2-binding protein mediate cell-cell adhesion
    • Inohara H, Akahani S, Koths K, Raz A. Interactions between galectin-3 and Mac-2-binding protein mediate cell-cell adhesion. Cancer Res. 1996;56:4530-4.
    • (1996) Cancer Res. , vol.56 , pp. 4530-4534
    • Inohara, H.1    Akahani, S.2    Koths, K.3    Raz, A.4
  • 127
    • 0033972059 scopus 로고    scopus 로고
    • Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: A new model for metastasis
    • Al-Mehdi AB, Tozawa K, Fisher AB, Shientag L, Lee A, Muschel RJ. Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis. Nat Med. 2000;6:100-2.
    • (2000) Nat Med. , vol.6 , pp. 100-102
    • Al-Mehdi, A.B.1    Tozawa, K.2    Fisher, A.B.3    Shientag, L.4    Lee, A.5    Muschel, R.J.6
  • 128
    • 34848915825 scopus 로고    scopus 로고
    • The oncofetal Thomsen-Friedenreich carbohydrate antigen in cancer progression
    • Yu LG. The oncofetal Thomsen-Friedenreich carbohydrate antigen in cancer progression. Glycoconj J. 2007;24:411-20.
    • (2007) Glycoconj J. , vol.24 , pp. 411-420
    • Yu, L.G.1
  • 129
    • 33846964873 scopus 로고    scopus 로고
    • Galectin-3 interaction with Thomsen-Friedenreich disaccharide on cancer-associated MUC1 causes increased cancer cell endothelial adhesion
    • Yu LG, Andrews N, Zhao Q, et al. Galectin-3 interaction with Thomsen-Friedenreich disaccharide on cancer-associated MUC1 causes increased cancer cell endothelial adhesion. J Biol Chem. 2007;282:773-81.
    • (2007) J Biol Chem. , vol.282 , pp. 773-781
    • Yu, L.G.1    Andrews, N.2    Zhao, Q.3
  • 130
    • 0035874890 scopus 로고    scopus 로고
    • The role of Thomsen-Friedenreich antigen in adhesion of human breast and prostate cancer cells to the endothelium
    • Glinsky VV, Glinsky GV, Rittenhouse-Olson K, et al. The role of Thomsen-Friedenreich antigen in adhesion of human breast and prostate cancer cells to the endothelium. Cancer Res. 2001;61:4851-7.
    • (2001) Cancer Res. , vol.61 , pp. 4851-4857
    • Glinsky, V.V.1    Glinsky, G.V.2    Rittenhouse-Olson, K.3
  • 131
    • 77953627018 scopus 로고    scopus 로고
    • Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis
    • Zhao Q, Barclay M, Hilkens J, et al. Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis. Mol Cancer. 2010;9:154.
    • (2010) Mol Cancer. , vol.9 , pp. 154
    • Zhao, Q.1    Barclay, M.2    Hilkens, J.3
  • 132
    • 79955463679 scopus 로고    scopus 로고
    • Circulating galectin-3 in the bloodstream: An emerging promoter of cancer metastasis
    • Yu LG. Circulating galectin-3 in the bloodstream: an emerging promoter of cancer metastasis. World J Gastrointest Oncol. 2010;2:177-80.
    • (2010) World J Gastrointest Oncol. , vol.2 , pp. 177-180
    • Yu, L.G.1
  • 133
    • 78651276266 scopus 로고    scopus 로고
    • Proinflammatory cytokines in breast cancer: Mechanisms of action and potential targets for therapeutics
    • Goldberg JE, Schwertfeger KL. Proinflammatory cytokines in breast cancer: mechanisms of action and potential targets for therapeutics. Curr Drug Targets. 2010;11:1133-46.
    • (2010) Curr Drug Targets. , vol.11 , pp. 1133-1146
    • Goldberg, J.E.1    Schwertfeger, K.L.2
  • 134
    • 84948946050 scopus 로고    scopus 로고
    • Interleukin 1β-A potential salivary biomarker for cancer progression?
    • Idris A, Ghazali NB, Koh D. Interleukin 1β-A potential salivary biomarker for cancer progression? Biomark Cancer. 2015;8(7):25-9.
    • (2015) Biomark Cancer. , vol.8 , Issue.7 , pp. 25-29
    • Idris, A.1    Ghazali, N.B.2    Koh, D.3
  • 135
    • 84877097538 scopus 로고    scopus 로고
    • Increased circulation of galectin-3 in cancer induces secretion of metastasis-promoting cytokines from blood vascular endothelium
    • Chen C, Duckworth CA, Zhao Q, Pritchard DM, Rhodes JM, Yu LG. Increased circulation of galectin-3 in cancer induces secretion of metastasis-promoting cytokines from blood vascular endothelium. Clin Cancer Res. 2013;19:1693-704.
    • (2013) Clin Cancer Res. , vol.19 , pp. 1693-1704
    • Chen, C.1    Duckworth, C.A.2    Zhao, Q.3    Pritchard, D.M.4    Rhodes, J.M.5    Yu, L.G.6
  • 136
    • 84922967611 scopus 로고    scopus 로고
    • Downregulating galectin-3 inhibits proinflammatory cytokine production by human monocyte-derived dendritic cells via RNA interference
    • Chen SS, Sun LW, Brickner H, Sun PQ. Downregulating galectin-3 inhibits proinflammatory cytokine production by human monocyte-derived dendritic cells via RNA interference. Cell Immunol. 2015;294:44-53.
    • (2015) Cell Immunol. , vol.294 , pp. 44-53
    • Chen, S.S.1    Sun, L.W.2    Brickner, H.3    Sun, P.Q.4
  • 137
    • 69949168492 scopus 로고    scopus 로고
    • Modified citrus pectin anti-metastatic properties: One bullet, multiple targets
    • Glinsky VV, Raz A. Modified citrus pectin anti-metastatic properties: one bullet, multiple targets. Carbohydr Res. 2009;344:1788-91.
    • (2009) Carbohydr Res. , vol.344 , pp. 1788-1791
    • Glinsky, V.V.1    Raz, A.2
  • 138
    • 0028916852 scopus 로고
    • Inhibition of spontaneous metastasis in a rat prostate cancer model by oral administration of modified citrus pectin
    • Pienta KJ, Naik H, Akhtar A, et al. Inhibition of spontaneous metastasis in a rat prostate cancer model by oral administration of modified citrus pectin. J Natl Cancer Inst. 1995;87:348-53.
    • (1995) J Natl Cancer Inst. , vol.87 , pp. 348-353
    • Pienta, K.J.1    Naik, H.2    Akhtar, A.3
  • 139
    • 20344384247 scopus 로고    scopus 로고
    • Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs
    • Glinskii OV, Huxley VH, Glinsky GV, Pienta KJ, Raz A, Glinsky VV. Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs. Neoplasia. 2005;7:522-7.
    • (2005) Neoplasia. , vol.7 , pp. 522-527
    • Glinskii, O.V.1    Huxley, V.H.2    Glinsky, G.V.3    Pienta, K.J.4    Raz, A.5    Glinsky, V.V.6
  • 140
    • 24944585018 scopus 로고    scopus 로고
    • A novel carbohydrate-based therapeutic GCS-100 overcomes bortezomib resistance and enhances dexamethasone-induced apoptosis in multiple myeloma cells
    • Chauhan D, Li G, Podar K, et al. A novel carbohydrate-based therapeutic GCS-100 overcomes bortezomib resistance and enhances dexamethasone-induced apoptosis in multiple myeloma cells. Cancer Res. 2005;65:8350-8.
    • (2005) Cancer Res. , vol.65 , pp. 8350-8358
    • Chauhan, D.1    Li, G.2    Podar, K.3
  • 141
    • 77952989057 scopus 로고    scopus 로고
    • GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death
    • Streetly MJ, Maharaj L, Joel S, Schey SA, Gribben JG, Cotter FE. GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death. Blood. 2010;115:3939-48.
    • (2010) Blood. , vol.115 , pp. 3939-3948
    • Streetly, M.J.1    Maharaj, L.2    Joel, S.3    Schey, S.A.4    Gribben, J.G.5    Cotter, F.E.6
  • 142
    • 40249098634 scopus 로고    scopus 로고
    • Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes
    • Demotte N, Stroobant V, Courtoy PJ, et al. Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes. Immunity. 2008;28:414-24.
    • (2008) Immunity. , vol.28 , pp. 414-424
    • Demotte, N.1    Stroobant, V.2    Courtoy, P.J.3
  • 143
    • 84898759431 scopus 로고    scopus 로고
    • A short treatment with galactomannan GM-CT-01 corrects the functions of freshly isolated human tumor-infiltrating lymphocytes
    • Demotte N, Bigirimana R, Wieërs G, et al. A short treatment with galactomannan GM-CT-01 corrects the functions of freshly isolated human tumor-infiltrating lymphocytes. Clin Cancer Res. 2014;20:1823-33.
    • (2014) Clin Cancer Res. , vol.20 , pp. 1823-1833
    • Demotte, N.1    Bigirimana, R.2    Wieërs, G.3


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