메뉴 건너뛰기




Volumn 10, Issue 10, 2015, Pages

Anti-tumor effects after adoptive transfer of IL-12 transposon-modified murine splenocytes in the OT-i-melanoma mouse model

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12; OVALBUMIN; TRANSPOSON;

EID: 84948986254     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0140744     Document Type: Article
Times cited : (10)

References (45)
  • 1
    • 0141688283 scopus 로고    scopus 로고
    • Adoptive-cell-transfer therapy for the treatment of patients with cancer
    • Dudley ME, Rosenberg SA. Adoptive-cell-transfer therapy for the treatment of patients with cancer. Nat Rev Cancer. 2003; 3(9):666-75.
    • (2003) Nat Rev Cancer. , vol.3 , Issue.9 , pp. 666-675
    • Dudley, M.E.1    Rosenberg, S.A.2
  • 4
    • 77950525914 scopus 로고    scopus 로고
    • A transposon and transposase system for human application
    • Hackett PB, Largaespada DA, Cooper LJ. A transposon and transposase system for human application. Mol Ther. 2010; 18(4):674-83.
    • (2010) Mol Ther. , vol.18 , Issue.4 , pp. 674-683
    • Hackett, P.B.1    Largaespada, D.A.2    Cooper, L.J.3
  • 5
    • 42349088534 scopus 로고    scopus 로고
    • Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system
    • PMID: 18413766
    • Singh H, Manuri PR, Olivares S, Dara N, Dawson MJ, Huls H, et al. Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system. Cancer Res. 2008; 68(8):2961-71. doi: 10.1158/0008-5472.CAN-07-5600 PMID: 18413766
    • (2008) Cancer Res. , vol.68 , Issue.8 , pp. 2961-2971
    • Singh, H.1    Manuri, P.R.2    Olivares, S.3    Dara, N.4    Dawson, M.J.5    Huls, H.6
  • 6
    • 84890209444 scopus 로고    scopus 로고
    • A new approach to gene therapy using Sleeping Beauty to genetically modify clinical-grade T cells to target CD19
    • Singh H, Huls H, Kebriaei P, Cooper LJ. A new approach to gene therapy using Sleeping Beauty to genetically modify clinical-grade T cells to target CD19. Immunol Rev. 2014; 257(1):181-90.
    • (2014) Immunol Rev. , vol.257 , Issue.1 , pp. 181-190
    • Singh, H.1    Huls, H.2    Kebriaei, P.3    Cooper, L.J.4
  • 7
    • 70349356638 scopus 로고    scopus 로고
    • Emerging potential of transposons for gene therapy and generation of induced pluripotent stem cells
    • PMID: 19471016
    • Vandendriessche T, Ivics Z, Izsvak Z, Chuah MK. Emerging potential of transposons for gene therapy and generation of induced pluripotent stem cells. Blood. 2009; 114(8):1461-8. doi: 10.1182/blood-2009-04-210427 PMID: 19471016
    • (2009) Blood. , vol.114 , Issue.8 , pp. 1461-1468
    • Vandendriessche, T.1    Ivics, Z.2    Izsvak, Z.3    Chuah, M.K.4
  • 8
    • 84863393501 scopus 로고    scopus 로고
    • Hyperactive piggyBac Gene Transfer in Human Cells and in Vivo
    • PMID: 21992617
    • Doherty JE, Huye LE, Yusa K, Zhou L, Craig NL, Wilson MH. Hyperactive piggyBac Gene Transfer in Human Cells and In Vivo. Human Gene Therapy. 2012; 23(3):311-20. doi: 10.1089/hum.2011.138 PMID: 21992617
    • (2012) Human Gene Therapy. , vol.23 , Issue.3 , pp. 311-320
    • Doherty, J.E.1    Huye, L.E.2    Yusa, K.3    Zhou, L.4    Craig, N.L.5    Wilson, M.H.6
  • 10
    • 83755224329 scopus 로고    scopus 로고
    • Mobilization of giant piggyBac transposons in the mouse genome
    • PMID: 21948799
    • Li MA, Turner DJ, Ning Z, Yusa K, Liang Q, Eckert S, et al. Mobilization of giant piggyBac transposons in the mouse genome. Nucleic Acids Res. 2011; 39(22):e148. doi: 10.1093/nar/gkr764 PMID: 21948799
    • (2011) Nucleic Acids Res. , vol.39 , Issue.22 , pp. e148
    • Li, M.A.1    Turner, D.J.2    Ning, Z.3    Yusa, K.4    Liang, Q.5    Eckert, S.6
  • 12
    • 0030152925 scopus 로고    scopus 로고
    • Precise excision ofTTAA-specificlepidopteran transposons piggyBac (IFP2) and tagalong (TFP3) from the baculovirus genome in cell lines from two species of Lepidoptera
    • Fraser MJ, Ciszczon T, Elick T, Bauser C. Precise excision ofTTAA-specificlepidopteran transposons piggyBac (IFP2) and tagalong (TFP3) from the baculovirus genome in cell lines from two species of Lepidoptera. Insect Mol Biol. 1996; 5(2):141-51.
    • (1996) Insect Mol Biol. , vol.5 , Issue.2 , pp. 141-151
    • Fraser, M.J.1    Ciszczon, T.2    Elick, T.3    Bauser, C.4
  • 13
    • 33845981514 scopus 로고    scopus 로고
    • Piggy Bac transposon-mediated gene transfer in human cells
    • PMID: 17164785
    • Wilson MH, Coates CJ, George AL Jr. Piggy Bac transposon-mediated gene transfer in human cells. Molecular Therapy. 2007; 15(1):139-45. PMID: 17164785
    • (2007) Molecular Therapy. , vol.15 , Issue.1 , pp. 139-145
    • Wilson, M.H.1    Coates, C.J.2    George, A.L.3
  • 14
    • 84871926959 scopus 로고    scopus 로고
    • Evaluation of Long-term Trans-gene Expression in piggyBac-Modified Human T Lymphocytes
    • PMID: 23211626
    • Nakazawa Y, Saha S, Galvan DL, Huye L, Rollins L, Rooney CM, et al. Evaluation of Long-term Trans-gene Expression in piggyBac-Modified Human T Lymphocytes. Journal of Immunotherapy. 2013; 36 (1):3-10. doi: 10.1097/CJI.0b013e3182791234 PMID: 23211626
    • (2013) Journal of Immunotherapy. , vol.36 , Issue.1 , pp. 3-10
    • Nakazawa, Y.1    Saha, S.2    Galvan, D.L.3    Huye, L.4    Rollins, L.5    Rooney, C.M.6
  • 15
    • 77950953208 scopus 로고    scopus 로고
    • PiggyBactransposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies
    • Manuri PV, Wilson MH, Maiti SN, Mi T, Singh H, Olivares S, et al. piggyBactransposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies. Hum Gene Ther. 2010; 21(4):427-37.
    • (2010) Hum Gene Ther. , vol.21 , Issue.4 , pp. 427-437
    • Manuri, P.V.1    Wilson, M.H.2    Maiti, S.N.3    Mi, T.4    Singh, H.5    Olivares, S.6
  • 16
    • 70349696650 scopus 로고    scopus 로고
    • Optimization of the Piggy Bac transposon system for the sustained genetic modification of human T lymphocytes
    • Nakazawa Y, Huye LE, Dotti G, Foster AE, Vera JF, Manuri PR, et al. Optimization of the Piggy Bac transposon system for the sustained genetic modification of human T lymphocytes. JImmunother. 2009; 32(8):826-36.
    • (2009) JImmunother. , vol.32 , Issue.8 , pp. 826-836
    • Nakazawa, Y.1    Huye, L.E.2    Dotti, G.3    Foster, A.E.4    Vera, J.F.5    Manuri, P.R.6
  • 17
    • 82955187824 scopus 로고    scopus 로고
    • Piggy Bac-mediatedcancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor
    • Nakazawa Y, Huye LE, Salsman VS, Leen AM, Ahmed N, Rollins L, et al. Piggy Bac-mediatedcancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor. Mol Ther. 2011; 19(12):2133-43.
    • (2011) Mol Ther. , vol.19 , Issue.12 , pp. 2133-2143
    • Nakazawa, Y.1    Huye, L.E.2    Salsman, V.S.3    Leen, A.M.4    Ahmed, N.5    Rollins, L.6
  • 18
    • 33645823860 scopus 로고    scopus 로고
    • Efficient nonviral gene delivery into primary lymphocytes from rats and mice
    • PMID: 16401643
    • Goffinet C, Keppler OT. Efficient nonviral gene delivery into primary lymphocytes from rats and mice. FASEB J. 2006; 20(3):500-2. PMID: 16401643
    • (2006) FASEB J. , vol.20 , Issue.3 , pp. 500-502
    • Goffinet, C.1    Keppler, O.T.2
  • 21
    • 78650871842 scopus 로고    scopus 로고
    • A Th1-inducing adenoviral vaccine for boosting adoptively transferred T cells
    • Song XT, Turnis ME, Zhou X, Zhu W, Hong BX, Rollins L, et al. A Th1-inducing adenoviral vaccine for boosting adoptively transferred T cells. Mol Ther. 2011; 19(1):211-7.
    • (2011) Mol Ther. , vol.19 , Issue.1 , pp. 211-217
    • Song, X.T.1    Turnis, M.E.2    Zhou, X.3    Zhu, W.4    Hong, B.X.5    Rollins, L.6
  • 22
    • 20244366111 scopus 로고    scopus 로고
    • Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
    • Dudley ME, Wunderlich JR, Yang JC, Sherry RM, Topalian SL, Restifo NP, et al. Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. JClin Oncol. 2005; 23(10):2346-57.
    • (2005) JClin Oncol. , vol.23 , Issue.10 , pp. 2346-2357
    • Dudley, M.E.1    Wunderlich, J.R.2    Yang, J.C.3    Sherry, R.M.4    Topalian, S.L.5    Restifo, N.P.6
  • 23
    • 55949125601 scopus 로고    scopus 로고
    • Adoptive cell therapy for patients with metastatic melanoma: Evaluation of intensive myeloablative chemoradiation preparative regimens
    • Dudley ME, Yang JC, Sherry R, Hughes MS, Royal R, Kammula U, et al. Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens. JClin Oncol. 2008; 26(32):5233-9.
    • (2008) JClin Oncol. , vol.26 , Issue.32 , pp. 5233-5239
    • Dudley, M.E.1    Yang, J.C.2    Sherry, R.3    Hughes, M.S.4    Royal, R.5    Kammula, U.6
  • 24
    • 33749624177 scopus 로고    scopus 로고
    • Cancer regression in patients after transfer of genetically engineered lymphocytes
    • PMID: 16946036
    • Morgan RA, Dudley ME, Wunderlich JR, Hughes MS, Yang JC, Sherry RM, et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science. 2006; 314(5796):126-9. PMID: 16946036
    • (2006) Science. , vol.314 , Issue.5796 , pp. 126-129
    • Morgan, R.A.1    Dudley, M.E.2    Wunderlich, J.R.3    Hughes, M.S.4    Yang, J.C.5    Sherry, R.M.6
  • 25
    • 0027303195 scopus 로고
    • Interleukin-12: A recently discovered cytokine with potential for enhancing cell-mediated immune responses to tumors
    • PMID: 8100734
    • Gately MK. Interleukin-12: a recently discovered cytokine with potential for enhancing cell-mediated immune responses to tumors. Cancer Invest. 1993; 11(4):500-6. PMID: 8100734
    • (1993) Cancer Invest. , vol.11 , Issue.4 , pp. 500-506
    • Gately, M.K.1
  • 26
    • 0027226015 scopus 로고
    • Effects of IL-12 on the generation of cytotoxic activity in human CD8+T lymphocytes
    • Mehrotra PT, Wu D, Crim JA, Mostowski HS, Siegel JP. Effects of IL-12 on the generation of cytotoxic activity in human CD8+T lymphocytes. JImmunol. 1993; 151(5):2444-52.
    • (1993) JImmunol. , vol.151 , Issue.5 , pp. 2444-2452
    • Mehrotra, P.T.1    Wu, D.2    Crim, J.A.3    Mostowski, H.S.4    Siegel, J.P.5
  • 27
    • 84863230570 scopus 로고    scopus 로고
    • Local delivery of interleukin-12 using T cells targeting VEGF receptor-2 eradicates multiple vascularized tumors in mice
    • Chinnasamy D, Yu Z, Kerkar SP, Zhang L, Morgan RA, Restifo NP, et al. Local delivery of interleukin-12 using T cells targeting VEGF receptor-2 eradicates multiple vascularized tumors in mice. Clin Cancer Res. 2012; 18(6):1672-83.
    • (2012) Clin Cancer Res. , vol.18 , Issue.6 , pp. 1672-1683
    • Chinnasamy, D.1    Yu, Z.2    Kerkar, S.P.3    Zhang, L.4    Morgan, R.A.5    Restifo, N.P.6
  • 28
    • 0035831628 scopus 로고    scopus 로고
    • Interleukin 12 gene therapy of cancer by peritumoral injection of transduced autologous fibroblasts: Outcome of a phase i study
    • Kang WK, Park C, Yoon HL, Kim WS, Yoon SS, Lee MH, et al. Interleukin 12 gene therapy of cancer by peritumoral injection of transduced autologous fibroblasts: outcome of a phase I study. Hum Gene Ther. 2001; 12(6):671-84.
    • (2001) Hum Gene Ther. , vol.12 , Issue.6 , pp. 671-684
    • Kang, W.K.1    Park, C.2    Yoon, H.L.3    Kim, W.S.4    Yoon, S.S.5    Lee, M.H.6
  • 29
    • 0029148905 scopus 로고
    • Cancer immunotherapy of established tumors with IL-12. Effective delivery by genetically engineered fibroblasts
    • Zitvogel L, Tahara H, Robbins PD, Storkus WJ, Clarke MR, Nalesnik MA, et al. Cancer immunotherapy of established tumors with IL-12. Effective delivery by genetically engineered fibroblasts. JImmunol. 1995; 155(3):1393-403.
    • (1995) J Immunol. , vol.155 , Issue.3 , pp. 1393-1403
    • Zitvogel, L.1    Tahara, H.2    Robbins, P.D.3    Storkus, W.J.4    Clarke, M.R.5    Nalesnik, M.A.6
  • 30
    • 0036594813 scopus 로고    scopus 로고
    • IL-12 plasmid delivery by in vivo electroporationforthe successful treatment of established subcutaneous B16.F10 melanoma
    • Lucas ML, Heller L, Coppola D, Heller R. IL-12 plasmid delivery by in vivo electroporationforthe successful treatment of established subcutaneous B16.F10 melanoma. Mol Ther. 2002; 5(6):668-75.
    • (2002) Mol Ther. , vol.5 , Issue.6 , pp. 668-675
    • Lucas, M.L.1    Heller, L.2    Coppola, D.3    Heller, R.4
  • 31
    • 0031923243 scopus 로고    scopus 로고
    • Optimal scheduling of interleukin-12 and fractionated radiation therapy in the murine Lewis lung carcinoma
    • Teicher BA, Ara G, Buxton D, Leonard J, Schaub RG. Optimal scheduling of interleukin-12 and fractionated radiation therapy in the murine Lewis lung carcinoma. Radiat Oncol Investig. 1998; 6(2):71-80.
    • (1998) Radiat Oncol Investig. , vol.6 , Issue.2 , pp. 71-80
    • Teicher, B.A.1    Ara, G.2    Buxton, D.3    Leonard, J.4    Schaub, R.G.5
  • 32
    • 84863145540 scopus 로고    scopus 로고
    • Hema Max, a recombinant human interleukin-12, is a potent mitigator of acute radiation injury in mice and non-human primates
    • Basile LA, Ellefson D, Gluzman-Poltorak Z, Junes-Gill K, Mar V, Mendonca S, et al. Hema Max, a recombinant human interleukin-12, is a potent mitigator of acute radiation injury in mice and non-human primates. PLoS One. 2012; 7(2):e30434.
    • (2012) PLoS One. , vol.7 , Issue.2 , pp. e30434
    • Basile, L.A.1    Ellefson, D.2    Gluzman-Poltorak, Z.3    Junes-Gill, K.4    Mar, V.5    Mendonca, S.6
  • 33
    • 79953325686 scopus 로고    scopus 로고
    • Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment
    • Zhang L, Kerkar SP, Yu Z, Zheng Z, Yang S, Restifo NP, et al. Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment. Mol Ther. 2011; 19(4):751-9.
    • (2011) Mol Ther. , vol.19 , Issue.4 , pp. 751-759
    • Zhang, L.1    Kerkar, S.P.2    Yu, Z.3    Zheng, Z.4    Yang, S.5    Restifo, N.P.6
  • 34
    • 84871926959 scopus 로고    scopus 로고
    • Evaluation of long-term trans-gene expression in piggyBac-modified human T lymphocytes
    • Nakazawa Y, Saha S, Galvan DL, Huye L, Rollins L, Rooney CM, et al. Evaluation of long-term trans-gene expression in piggyBac-modified human T lymphocytes. JImmunother. 2013; 36(1):3-10.
    • (2013) JImmunother. , vol.36 , Issue.1 , pp. 3-10
    • Nakazawa, Y.1    Saha, S.2    Galvan, D.L.3    Huye, L.4    Rollins, L.5    Rooney, C.M.6
  • 35
    • 33845981514 scopus 로고    scopus 로고
    • Piggy Bac Transposon-mediated Gene Transfer in Human Cells
    • Wilson MH, Coates CJ, George AL Jr. Piggy Bac Transposon-mediated Gene Transfer in Human Cells. Mol Ther. 2007; 15(1):139-45.
    • (2007) Mol Ther. , vol.15 , Issue.1 , pp. 139-145
    • Wilson, M.H.1    Coates, C.J.2    George, A.L.3
  • 36
    • 84875138464 scopus 로고    scopus 로고
    • Evaluating risks of insertional mutagenesis by DNAtransposons in gene therapy
    • Hackett PB, Largaespada DA, Switzer KC, Cooper LJ. Evaluating risks of insertional mutagenesis by DNAtransposons in gene therapy. Transl Res. 2013; 161(4):265-83.
    • (2013) Transl Res. , vol.161 , Issue.4 , pp. 265-283
    • Hackett, P.B.1    Largaespada, D.A.2    Switzer, K.C.3    Cooper, L.J.4
  • 37
    • 77956668327 scopus 로고    scopus 로고
    • Translating Sleeping Beauty transposition into cellular therapies: Victories and challenges
    • PMID: 20652893
    • Izsvak Z, Hackett PB, Cooper LJ, Ivics Z. Translating Sleeping Beauty transposition into cellular therapies: victories and challenges. Bioessays. 2010; 32(9):756-67. doi: 10.1002/bies.201000027 PMID: 20652893
    • (2010) Bioessays. , vol.32 , Issue.9 , pp. 756-767
    • Izsvak, Z.1    Hackett, P.B.2    Cooper, L.J.3    Ivics, Z.4
  • 38
    • 0030887047 scopus 로고    scopus 로고
    • Phase i evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies
    • Atkins MB, Robertson MJ, Gordon M, Lotze MT, De Coste M, Du Bois JS, et al. Phase I evaluation of intravenous recombinant human interleukin 12 in patients with advanced malignancies. Clin Cancer Res. 1997; 3(3):409-17.
    • (1997) Clin Cancer Res. , vol.3 , Issue.3 , pp. 409-417
    • Atkins, M.B.1    Robertson, M.J.2    Gordon, M.3    Lotze, M.T.4    De Coste, M.5    Du Bois, J.S.6
  • 40
    • 0030766971 scopus 로고    scopus 로고
    • Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production
    • PMID: 9326219
    • Leonard JP, Sherman ML, Fisher GL, Buchanan LJ, Larsen G, Atkins MB, et al. Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production. Blood. 1997; 90(7):2541-8. PMID: 9326219
    • (1997) Blood. , vol.90 , Issue.7 , pp. 2541-2548
    • Leonard, J.P.1    Sherman, M.L.2    Fisher, G.L.3    Buchanan, L.J.4    Larsen, G.5    Atkins, M.B.6
  • 41
    • 58049200809 scopus 로고    scopus 로고
    • Phase i trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma
    • Daud AI, De Conti RC, Andrews S, Urbas P, Riker AI, Sondak VK, et al. Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma. JClin Oncol. 2008; 26(36):5896-903.
    • (2008) JClin Oncol. , vol.26 , Issue.36 , pp. 5896-5903
    • Daud, A.I.1    De Conti, R.C.2    Andrews, S.3    Urbas, P.4    Riker, A.I.5    Sondak, V.K.6
  • 42
    • 77956280888 scopus 로고    scopus 로고
    • Tumor-specific CD8+T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts
    • PMID: 20647327
    • Kerkar SP, Muranski P, Kaiser A, Boni A, Sanchez-Perez L, Yu Z, et al. Tumor-specific CD8+T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts. Cancer Res. 2010; 70(17):6725-34. doi: 10.1158/0008-5472.CAN-10-0735 PMID: 20647327
    • (2010) Cancer Res. , vol.70 , Issue.17 , pp. 6725-6734
    • Kerkar, S.P.1    Muranski, P.2    Kaiser, A.3    Boni, A.4    Sanchez-Perez, L.5    Yu, Z.6
  • 43
    • 0031852722 scopus 로고    scopus 로고
    • Gp100/pmel 17 is a murine tumor rejection antigen: Induction of "self-reactive, tumoricidal T cells using high-affinity, altered peptide ligand
    • Overwijk WW, Tsung A, Irvine KR, Parkhurst MR, Goletz TJ, Tsung K, et al. gp100/pmel 17 is a murine tumor rejection antigen: induction of "self-reactive, tumoricidal T cells using high-affinity, altered peptide ligand. JExp Med. 1998; 188(2):277-86.
    • (1998) JExp Med. , vol.188 , Issue.2 , pp. 277-286
    • Overwijk, W.W.1    Tsung, A.2    Irvine, K.R.3    Parkhurst, M.R.4    Goletz, T.J.5    Tsung, K.6
  • 44
    • 84953344459 scopus 로고    scopus 로고
    • The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity
    • PMID: 25212991
    • Hudecek M, Sommermeyer D, Kosasih PL, Silva-Benedict A, Liu L, Rader C, et al. The nonsignaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity. Cancer Immunol Res. 2015; 3(2):125-35. doi: 10.1158/2326-6066.CIR-14-0127 PMID: 25212991
    • (2015) Cancer Immunol Res. , vol.3 , Issue.2 , pp. 125-135
    • Hudecek, M.1    Sommermeyer, D.2    Kosasih, P.L.3    Silva-Benedict, A.4    Liu, L.5    Rader, C.6
  • 45
    • 84921487573 scopus 로고    scopus 로고
    • Designing chimeric antigen receptors to effectively and safely target tumors
    • PMID: 25621840
    • Jensen MC, Riddell SR. Designing chimeric antigen receptors to effectively and safely target tumors. Curr Opin Immunol. 2015; 33:9-15. doi: 10.1016/j.coi.2015.01.002 PMID: 25621840
    • (2015) Curr Opin Immunol. , vol.33 , pp. 9-15
    • Jensen, M.C.1    Riddell, S.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.