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Volumn 42, Issue , 2015, Pages 555-567

Virology: The next generation from digital PCR to single virion genomics

Author keywords

Digital multiple displacement amplification; Digital PCR; Quantitative PCR; Single virion genomics; Viral load testing

Indexed keywords


EID: 84948799711     PISSN: 05809517     EISSN: None     Source Type: Book Series    
DOI: 10.1016/bs.mim.2015.09.001     Document Type: Chapter
Times cited : (1)

References (64)
  • 2
    • 40249095175 scopus 로고    scopus 로고
    • Something from (almost) nothing: The impact of multiple displacement amplification on microbial ecology
    • Binga E.K., Lasken R.S., Neufeld J.D. Something from (almost) nothing: The impact of multiple displacement amplification on microbial ecology. ISME Journal 2008, 2(3):233-241. 10.1038/ismej.2008.10.
    • (2008) ISME Journal , vol.2 , Issue.3 , pp. 233-241
    • Binga, E.K.1    Lasken, R.S.2    Neufeld, J.D.3
  • 3
    • 79952351866 scopus 로고    scopus 로고
    • Digital MDA for enumeration of total nucleic acid contamination
    • Blainey P.C., Quake S.R. Digital MDA for enumeration of total nucleic acid contamination. Nucleic Acids Research 2011, 39(4):e19. 10.1093/nar/gkq1074.
    • (2011) Nucleic Acids Research , vol.39 , Issue.4 , pp. e19
    • Blainey, P.C.1    Quake, S.R.2
  • 4
    • 84906851659 scopus 로고    scopus 로고
    • Could droplet digital PCR be used instead of real-time PCR for quantitative detection of the hepatitis B virus genome in plasma?
    • Boizeau L., Laperche S., Desire N., Jourdain C., Thibault V., Servant-Delmas A. Could droplet digital PCR be used instead of real-time PCR for quantitative detection of the hepatitis B virus genome in plasma?. Journal of Clinical Microbiology 2014, 52(9):3497-3498. 10.1128/JCM.01306-14.
    • (2014) Journal of Clinical Microbiology , vol.52 , Issue.9 , pp. 3497-3498
    • Boizeau, L.1    Laperche, S.2    Desire, N.3    Jourdain, C.4    Thibault, V.5    Servant-Delmas, A.6
  • 5
    • 36949088975 scopus 로고
    • An unstable intermediate carrying information from genes to ribosomes for protein synthesis
    • Brenner S., Jacob F., Meselson M. An unstable intermediate carrying information from genes to ribosomes for protein synthesis. Nature 1961, 190:576-581.
    • (1961) Nature , vol.190 , pp. 576-581
    • Brenner, S.1    Jacob, F.2    Meselson, M.3
  • 7
    • 77951299065 scopus 로고    scopus 로고
    • Absolute quantification of genetically modified MON810 maize (Zea mays L.) by digital polymerase chain reaction
    • Corbisier P., Bhat S., Partis L., Xie V.R., Emslie K.R. Absolute quantification of genetically modified MON810 maize (Zea mays L.) by digital polymerase chain reaction. Analytical and Bioanalytical Chemistry 2010, 396(6):2143-2150. 10.1007/s00216-009-3200-3.
    • (2010) Analytical and Bioanalytical Chemistry , vol.396 , Issue.6 , pp. 2143-2150
    • Corbisier, P.1    Bhat, S.2    Partis, L.3    Xie, V.R.4    Emslie, K.R.5
  • 8
    • 84923330734 scopus 로고    scopus 로고
    • A comparative study of digital RT-PCR and RT-qPCR for quantification of Hepatitis A virus and Norovirus in lettuce and water samples
    • Coudray-Meunier C., Fraisse A., Martin-Latil S., Guillier L., Delannoy S., Fach P., et al. A comparative study of digital RT-PCR and RT-qPCR for quantification of Hepatitis A virus and Norovirus in lettuce and water samples. International Journal of Food Microbiology 2015, 201:17-26. 10.1016/j.ijfoodmicro.2015.02.006.
    • (2015) International Journal of Food Microbiology , vol.201 , pp. 17-26
    • Coudray-Meunier, C.1    Fraisse, A.2    Martin-Latil, S.3    Guillier, L.4    Delannoy, S.5    Fach, P.6
  • 10
  • 12
    • 0034830935 scopus 로고    scopus 로고
    • Rapid amplification of plasmid and phage DNA using Phi 29 DNA polymerase and multiply-primed rolling circle amplification
    • Dean F.B., Nelson J.R., Giesler T.L., Lasken R.S. Rapid amplification of plasmid and phage DNA using Phi 29 DNA polymerase and multiply-primed rolling circle amplification. Genome Research 2001, 11(6):1095-1099. 10.1101/gr.180501.
    • (2001) Genome Research , vol.11 , Issue.6 , pp. 1095-1099
    • Dean, F.B.1    Nelson, J.R.2    Giesler, T.L.3    Lasken, R.S.4
  • 13
    • 84937861923 scopus 로고    scopus 로고
    • Clinical utility of cytomegalovirus viral load in solid organ transplant recipients
    • Dioverti M.V., Razonable R.R. Clinical utility of cytomegalovirus viral load in solid organ transplant recipients. Current Opinion in Infectious Diseases 2015, 28(4):317-322. 10.1097/QCO.0000000000000173.
    • (2015) Current Opinion in Infectious Diseases , vol.28 , Issue.4 , pp. 317-322
    • Dioverti, M.V.1    Razonable, R.R.2
  • 15
    • 0017235043 scopus 로고
    • Complete nucleotide sequence of bacteriophage MS2 RNA: Primary and secondary structure of the replicase gene
    • Fiers W., Contreras R., Duerinck F., Haegeman G., Iserentant D., Merregaert J., et al. Complete nucleotide sequence of bacteriophage MS2 RNA: Primary and secondary structure of the replicase gene. Nature 1976, 260(5551):500-507.
    • (1976) Nature , vol.260 , Issue.5551 , pp. 500-507
    • Fiers, W.1    Contreras, R.2    Duerinck, F.3    Haegeman, G.4    Iserentant, D.5    Merregaert, J.6
  • 16
    • 84920517663 scopus 로고    scopus 로고
    • Quantitative nucleic acid amplification methods for viral infections
    • Gullett J.C., Nolte F.S. Quantitative nucleic acid amplification methods for viral infections. Clinical Chemistry 2015, 61(1):72-78. 10.1373/clinchem.2014.223289.
    • (2015) Clinical Chemistry , vol.61 , Issue.1 , pp. 72-78
    • Gullett, J.C.1    Nolte, F.S.2
  • 17
    • 84898974145 scopus 로고    scopus 로고
    • The potential advantages of digital PCR for clinical virology diagnostics
    • Hall Sedlak R., Jerome K.R. The potential advantages of digital PCR for clinical virology diagnostics. Expert Review of Molecular Diagnostics 2014, 14(4):501-507. 10.1586/14737159.2014.910456.
    • (2014) Expert Review of Molecular Diagnostics , vol.14 , Issue.4 , pp. 501-507
    • Hall Sedlak, R.1    Jerome, K.R.2
  • 18
    • 84873048768 scopus 로고    scopus 로고
    • Comparison of droplet digital PCR to real-time PCR for quantitative detection of cytomegalovirus
    • Hayden R.T., Gu Z., Ingersoll J., Abdul-Ali D., Shi L., Pounds S., et al. Comparison of droplet digital PCR to real-time PCR for quantitative detection of cytomegalovirus. Journal of Clinical Microbiology 2013, 51(2):540-546. 10.1128/JCM.02620-12.
    • (2013) Journal of Clinical Microbiology , vol.51 , Issue.2 , pp. 540-546
    • Hayden, R.T.1    Gu, Z.2    Ingersoll, J.3    Abdul-Ali, D.4    Shi, L.5    Pounds, S.6
  • 19
    • 84928011489 scopus 로고    scopus 로고
    • Comparative evaluation of three commercial quantitative cytomegalovirus standards by use of digital and real-time PCR
    • Hayden R.T., Gu Z., Sam S.S., Sun Y., Tang L., Pounds S., et al. Comparative evaluation of three commercial quantitative cytomegalovirus standards by use of digital and real-time PCR. Journal of Clinical Microbiology 2015, 53(5):1500-1505. 10.1128/JCM.03375-14.
    • (2015) Journal of Clinical Microbiology , vol.53 , Issue.5 , pp. 1500-1505
    • Hayden, R.T.1    Gu, Z.2    Sam, S.S.3    Sun, Y.4    Tang, L.5    Pounds, S.6
  • 20
    • 0002610948 scopus 로고
    • Independent functions of viral protein and nucleic acid in growth of bacteriophage
    • Hershey A.D., Chase M. Independent functions of viral protein and nucleic acid in growth of bacteriophage. Journal of General Physiology 1952, 36(1):39-56.
    • (1952) Journal of General Physiology , vol.36 , Issue.1 , pp. 39-56
    • Hershey, A.D.1    Chase, M.2
  • 21
    • 84920528661 scopus 로고    scopus 로고
    • Next generation digital PCR measurement of hepatitis B virus copy number in formalin-fixed paraffin-embedded hepatocellular carcinoma tissue
    • Huang J.T., Liu Y.J., Wang J., Xu Z.G., Yang Y., Shen F., et al. Next generation digital PCR measurement of hepatitis B virus copy number in formalin-fixed paraffin-embedded hepatocellular carcinoma tissue. Clinical Chemistry 2015, 61(1):290-296. 10.1373/clinchem.2014.230227.
    • (2015) Clinical Chemistry , vol.61 , Issue.1 , pp. 290-296
    • Huang, J.T.1    Liu, Y.J.2    Wang, J.3    Xu, Z.G.4    Yang, Y.5    Shen, F.6
  • 22
    • 84920545307 scopus 로고    scopus 로고
    • Considerations for digital PCR as an accurate molecular diagnostic tool
    • Huggett J.F., Cowen S., Foy C.A. Considerations for digital PCR as an accurate molecular diagnostic tool. Clinical Chemistry 2015, 61(1):79-88. 10.1373/clinchem.2014.221366.
    • (2015) Clinical Chemistry , vol.61 , Issue.1 , pp. 79-88
    • Huggett, J.F.1    Cowen, S.2    Foy, C.A.3
  • 23
    • 84878431927 scopus 로고    scopus 로고
    • The digital MIQE guidelines: Minimum Information for Publication of Quantitative Digital PCR Experiments
    • Huggett J.F., Foy C.A., Benes V., Emslie K., Garson J.A., Haynes R., et al. The digital MIQE guidelines: Minimum Information for Publication of Quantitative Digital PCR Experiments. Clinical Chemistry 2013, 59(6):892-902. 10.1373/clinchem.2013.206375.
    • (2013) Clinical Chemistry , vol.59 , Issue.6 , pp. 892-902
    • Huggett, J.F.1    Foy, C.A.2    Benes, V.3    Emslie, K.4    Garson, J.A.5    Haynes, R.6
  • 25
    • 84896920831 scopus 로고    scopus 로고
    • Comparison of droplet digital PCR and seminested real-time PCR for quantification of cell-associated HIV-1 RNA
    • Kiselinova M., Pasternak A.O., De Spiegelaere W., Vogelaers D., Berkhout B., Vandekerckhove L. Comparison of droplet digital PCR and seminested real-time PCR for quantification of cell-associated HIV-1 RNA. PLoS One 2014, 9(1):e85999. 10.1371/journal.pone.0085999.
    • (2014) PLoS One , vol.9 , Issue.1 , pp. e85999
    • Kiselinova, M.1    Pasternak, A.O.2    De Spiegelaere, W.3    Vogelaers, D.4    Berkhout, B.5    Vandekerckhove, L.6
  • 27
    • 34247489656 scopus 로고    scopus 로고
    • Mechanism of chimera formation during the Multiple Displacement Amplification reaction
    • Lasken R.S., Stockwell T.B. Mechanism of chimera formation during the Multiple Displacement Amplification reaction. BMC Biotechnology 2007, 7:19. 10.1186/1472-6750-7-19.
    • (2007) BMC Biotechnology , vol.7 , pp. 19
    • Lasken, R.S.1    Stockwell, T.B.2
  • 28
    • 84929463919 scopus 로고    scopus 로고
    • Clinical relevance of KRAS-mutated subclones detected with picodroplet digital PCR in advanced colorectal cancer treated with anti-EGFR therapy
    • Laurent-Puig P., Pekin D., Normand C., Kotsopoulos S.K., Nizard P., Perez-Toralla K., et al. Clinical relevance of KRAS-mutated subclones detected with picodroplet digital PCR in advanced colorectal cancer treated with anti-EGFR therapy. Clinical Cancer Research 2015, 21(5):1087-1097. 10.1158/1078-0432.CCR-14-0983.
    • (2015) Clinical Cancer Research , vol.21 , Issue.5 , pp. 1087-1097
    • Laurent-Puig, P.1    Pekin, D.2    Normand, C.3    Kotsopoulos, S.K.4    Nizard, P.5    Perez-Toralla, K.6
  • 29
    • 84899742303 scopus 로고    scopus 로고
    • Coinfection of human herpesviruses 6A (HHV-6A) and HHV-6B as demonstrated by novel digital droplet PCR assay
    • Leibovitch E.C., Brunetto G.S., Caruso B., Fenton K., Ohayon J., Reich D.S., et al. Coinfection of human herpesviruses 6A (HHV-6A) and HHV-6B as demonstrated by novel digital droplet PCR assay. PLoS One 2014, 9(3):e92328. 10.1371/journal.pone.0092328.
    • (2014) PLoS One , vol.9 , Issue.3 , pp. e92328
    • Leibovitch, E.C.1    Brunetto, G.S.2    Caruso, B.3    Fenton, K.4    Ohayon, J.5    Reich, D.S.6
  • 30
    • 84937512231 scopus 로고    scopus 로고
    • Virus hunting
    • Lipkin W.I., Anthony S.J. Virus hunting. Virology 2015, 479-480:194-199. 10.1016/j.virol.2015.02.006.
    • (2015) Virology , pp. 194-199
    • Lipkin, W.I.1    Anthony, S.J.2
  • 31
    • 84905265997 scopus 로고    scopus 로고
    • Droplet digital PCR as a useful tool for the quantitative detection of Enterovirus 71
    • Lui Y.L., Tan E.L. Droplet digital PCR as a useful tool for the quantitative detection of Enterovirus 71. Journal of Virological Methods 2014, 207:200-203. 10.1016/j.jviromet.2014.07.014.
    • (2014) Journal of Virological Methods , vol.207 , pp. 200-203
    • Lui, Y.L.1    Tan, E.L.2
  • 34
    • 84921794995 scopus 로고    scopus 로고
    • Accurate quantification of episomal HIV-1 two-long terminal repeat circles by use of optimized DNA isolation and droplet digital PCR
    • Malatinkova E., Kiselinova M., Bonczkowski P., Trypsteen W., Messiaen P., Vermeire J., et al. Accurate quantification of episomal HIV-1 two-long terminal repeat circles by use of optimized DNA isolation and droplet digital PCR. Journal of Clinical Microbiology 2015, 53(2):699-701. 10.1128/JCM.03087-14.
    • (2015) Journal of Clinical Microbiology , vol.53 , Issue.2 , pp. 699-701
    • Malatinkova, E.1    Kiselinova, M.2    Bonczkowski, P.3    Trypsteen, W.4    Messiaen, P.5    Vermeire, J.6
  • 35
    • 84926418348 scopus 로고    scopus 로고
    • Caught in the middle with multiple displacement amplification: The myth of pooling for avoiding multiple displacement amplification bias in a metagenome
    • Marine R., McCarren C., Vorrasane V., Nasko D., Crowgey E., Polson S.W., et al. Caught in the middle with multiple displacement amplification: The myth of pooling for avoiding multiple displacement amplification bias in a metagenome. Microbiome 2014, 2(1):3. 10.1186/2049-2618-2-3.
    • (2014) Microbiome , vol.2 , Issue.1 , pp. 3
    • Marine, R.1    McCarren, C.2    Vorrasane, V.3    Nasko, D.4    Crowgey, E.5    Polson, S.W.6
  • 36
    • 84923259351 scopus 로고    scopus 로고
    • Digital droplet PCR: CNV analysis and other applications
    • Mazaika E., Homsy J. Digital droplet PCR: CNV analysis and other applications. Current Protocols in Human Genetics 2014, 82:7.24.1-7.24.13. 10.1002/0471142905.hg0724s82.
    • (2014) Current Protocols in Human Genetics , vol.82 , pp. 7.24.1-7.24.13
    • Mazaika, E.1    Homsy, J.2
  • 38
    • 84904895524 scopus 로고    scopus 로고
    • High-throughput and sensitive next-generation droplet digital PCR assay for the quantitation of the hepatitis C virus mutation at core amino acid 70
    • Mukaide M., Sugiyama M., Korenaga M., Murata K., Kanto T., Masaki N., et al. High-throughput and sensitive next-generation droplet digital PCR assay for the quantitation of the hepatitis C virus mutation at core amino acid 70. Journal of Virological Methods 2014, 207:169-177. 10.1016/j.jviromet.2014.07.006.
    • (2014) Journal of Virological Methods , vol.207 , pp. 169-177
    • Mukaide, M.1    Sugiyama, M.2    Korenaga, M.3    Murata, K.4    Kanto, T.5    Masaki, N.6
  • 39
    • 84899799072 scopus 로고    scopus 로고
    • Comparative study of sensitivity, linearity, and resistance to inhibition of digital and nondigital polymerase chain reaction and loop mediated isothermal amplification assays for quantification of human cytomegalovirus
    • Nixon G., Garson J.A., Grant P., Nastouli E., Foy C.A., Huggett J.F. Comparative study of sensitivity, linearity, and resistance to inhibition of digital and nondigital polymerase chain reaction and loop mediated isothermal amplification assays for quantification of human cytomegalovirus. Analytical Chemistry 2014, 86(9):4387-4394. 10.1021/ac500208w.
    • (2014) Analytical Chemistry , vol.86 , Issue.9 , pp. 4387-4394
    • Nixon, G.1    Garson, J.A.2    Grant, P.3    Nastouli, E.4    Foy, C.A.5    Huggett, J.F.6
  • 40
    • 84929945463 scopus 로고    scopus 로고
    • Laboratory diagnosis of noroviruses: Present and future
    • Pang X., Lee B.E. Laboratory diagnosis of noroviruses: Present and future. Clinics in Laboratory Medicine 2015, 35(2):345-362. 10.1016/j.cll.2015.02.008.
    • (2015) Clinics in Laboratory Medicine , vol.35 , Issue.2 , pp. 345-362
    • Pang, X.1    Lee, B.E.2
  • 41
    • 84941576507 scopus 로고    scopus 로고
    • Validation of an ultrasensitive digital droplet PCR assay for HIV-2 plasma RNA quantification
    • Ruelle J., Yfantis V., Duquenne A., Goubau P. Validation of an ultrasensitive digital droplet PCR assay for HIV-2 plasma RNA quantification. Journal of the International AIDS Society 2014, 17(4 Suppl. 3):19675. 10.7448/IAS.17.4.19675.
    • (2014) Journal of the International AIDS Society , vol.17 , Issue.4 , pp. 19675
    • Ruelle, J.1    Yfantis, V.2    Duquenne, A.3    Goubau, P.4
  • 42
    • 79958074870 scopus 로고    scopus 로고
    • Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism
    • Sanders S.J., Ercan-Sencicek A.G., Hus V., Luo R., Murtha M.T., Moreno-De-Luca D., et al. Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism. Neuron 2011, 70(5):863-885. 10.1016/j.neuron.2011.05.002.
    • (2011) Neuron , vol.70 , Issue.5 , pp. 863-885
    • Sanders, S.J.1    Ercan-Sencicek, A.G.2    Hus, V.3    Luo, R.4    Murtha, M.T.5    Moreno-De-Luca, D.6
  • 46
    • 84898984300 scopus 로고    scopus 로고
    • Identification of chromosomally integrated human herpesvirus 6 by droplet digital PCR
    • Sedlak R.H., Cook L., Huang M.L., Magaret A., Zerr D.M., Boeckh M., et al. Identification of chromosomally integrated human herpesvirus 6 by droplet digital PCR. Clinical Chemistry 2014, 60(5):765-772. 10.1373/clinchem.2013.217240.
    • (2014) Clinical Chemistry , vol.60 , Issue.5 , pp. 765-772
    • Sedlak, R.H.1    Cook, L.2    Huang, M.L.3    Magaret, A.4    Zerr, D.M.5    Boeckh, M.6
  • 47
    • 84870758826 scopus 로고    scopus 로고
    • Viral diagnostics in the era of digital polymerase chain reaction
    • Sedlak R.H., Jerome K.R. Viral diagnostics in the era of digital polymerase chain reaction. Diagnostic Microbiology and Infectious Disease 2013, 75(1):1-4. 10.1016/j.diagmicrobio.2012.10.009.
    • (2013) Diagnostic Microbiology and Infectious Disease , vol.75 , Issue.1 , pp. 1-4
    • Sedlak, R.H.1    Jerome, K.R.2
  • 48
    • 84919339207 scopus 로고    scopus 로고
    • A multiplexed droplet digital PCR assay performs better than qPCR on inhibition prone samples
    • Sedlak R.H., Kuypers J., Jerome K.R. A multiplexed droplet digital PCR assay performs better than qPCR on inhibition prone samples. Diagnostic Microbiology and Infectious Disease 2014, 80(4):285-286. 10.1016/j.diagmicrobio.2014.09.004.
    • (2014) Diagnostic Microbiology and Infectious Disease , vol.80 , Issue.4 , pp. 285-286
    • Sedlak, R.H.1    Kuypers, J.2    Jerome, K.R.3
  • 49
    • 0026537986 scopus 로고
    • Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors
    • Sidransky D., Tokino T., Hamilton S.R., Kinzler K.W., Levin B., Frost P., et al. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science 1992, 256(5053):102-105.
    • (1992) Science , vol.256 , Issue.5053 , pp. 102-105
    • Sidransky, D.1    Tokino, T.2    Hamilton, S.R.3    Kinzler, K.W.4    Levin, B.5    Frost, P.6
  • 52
    • 84875712178 scopus 로고    scopus 로고
    • Highly precise measurement of HIV DNA by droplet digital PCR
    • Strain M.C., Lada S.M., Luong T., Rought S.E., Gianella S., Terry V.H., et al. Highly precise measurement of HIV DNA by droplet digital PCR. PLoS One 2013, 8(4):e55943. 10.1371/journal.pone.0055943.
    • (2013) PLoS One , vol.8 , Issue.4 , pp. e55943
    • Strain, M.C.1    Lada, S.M.2    Luong, T.3    Rought, S.E.4    Gianella, S.5    Terry, V.H.6
  • 53
    • 25144506135 scopus 로고    scopus 로고
    • Viruses in the sea
    • Suttle C.A. Viruses in the sea. Nature 2005, 437(7057):356-361. 10.1038/nature04160.
    • (2005) Nature , vol.437 , Issue.7057 , pp. 356-361
    • Suttle, C.A.1
  • 55
    • 79959855149 scopus 로고    scopus 로고
    • Probing individual environmental bacteria for viruses by using microfluidic digital PCR
    • Tadmor A.D., Ottesen E.A., Leadbetter J.R., Phillips R. Probing individual environmental bacteria for viruses by using microfluidic digital PCR. Science 2011, 333(6038):58-62. 10.1126/science.1200758.
    • (2011) Science , vol.333 , Issue.6038 , pp. 58-62
    • Tadmor, A.D.1    Ottesen, E.A.2    Leadbetter, J.R.3    Phillips, R.4
  • 56
    • 84937859372 scopus 로고    scopus 로고
    • Cytomegalovirus load at treatment initiation is predictive of time to resolution of viremia and duration of therapy in hematopoietic cell transplant recipients
    • Tan S.K., Waggoner J.J., Pinsky B.A. Cytomegalovirus load at treatment initiation is predictive of time to resolution of viremia and duration of therapy in hematopoietic cell transplant recipients. Journal of Clinical Virology 2015, 69:179-183. 10.1016/j.jcv.2015.06.006.
    • (2015) Journal of Clinical Virology , vol.69 , pp. 179-183
    • Tan, S.K.1    Waggoner, J.J.2    Pinsky, B.A.3
  • 58
    • 0036070576 scopus 로고    scopus 로고
    • Bacteriophage control of bacterial virulence
    • Wagner P.L., Waldor M.K. Bacteriophage control of bacterial virulence. Infection and Immunity 2002, 70(8):3985-3993.
    • (2002) Infection and Immunity , vol.70 , Issue.8 , pp. 3985-3993
    • Wagner, P.L.1    Waldor, M.K.2
  • 59
    • 0014690791 scopus 로고
    • The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis
    • Weber K., Osborn M. The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. Journal of Biological Chemistry 1969, 244(16):4406-4412.
    • (1969) Journal of Biological Chemistry , vol.244 , Issue.16 , pp. 4406-4412
    • Weber, K.1    Osborn, M.2
  • 60
    • 64849115804 scopus 로고    scopus 로고
    • Digital PCR provides sensitive and absolute calibration for high throughput sequencing
    • White R.A., Blainey P.C., Fan H.C., Quake S.R. Digital PCR provides sensitive and absolute calibration for high throughput sequencing. BMC Genomics 2009, 10:116. 10.1186/1471-2164-10-116.
    • (2009) BMC Genomics , vol.10 , pp. 116
    • White, R.A.1    Blainey, P.C.2    Fan, H.C.3    Quake, S.R.4
  • 61
    • 84855232054 scopus 로고    scopus 로고
    • Digital PCR provides absolute quantitation of viral load for an occult RNA virus
    • White R.A., Quake S.R., Curr K. Digital PCR provides absolute quantitation of viral load for an occult RNA virus. Journal of Virological Methods 2012, 179(1):45-50. 10.1016/j.jviromet.2011.09.017.
    • (2012) Journal of Virological Methods , vol.179 , Issue.1 , pp. 45-50
    • White, R.A.1    Quake, S.R.2    Curr, K.3
  • 62
    • 84872451505 scopus 로고    scopus 로고
    • Phage-induced diversification improves host evolvability
    • Williams H.T. Phage-induced diversification improves host evolvability. BMC Evolutionary Biology 2013, 13:17. 10.1186/1471-2148-13-17.
    • (2013) BMC Evolutionary Biology , vol.13 , pp. 17
    • Williams, H.T.1
  • 64
    • 79958787922 scopus 로고    scopus 로고
    • Multiplex digital PCR: Breaking the one target per color barrier of quantitative PCR
    • Zhong Q., Bhattacharya S., Kotsopoulos S., Olson J., Taly V., Griffiths A.D., et al. Multiplex digital PCR: Breaking the one target per color barrier of quantitative PCR. Lab on a Chip 2011, 11(13):2167-2174. 10.1039/c1lc20126c.
    • (2011) Lab on a Chip , vol.11 , Issue.13 , pp. 2167-2174
    • Zhong, Q.1    Bhattacharya, S.2    Kotsopoulos, S.3    Olson, J.4    Taly, V.5    Griffiths, A.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.