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Volumn 51, Issue 98, 2015, Pages 17435-17438

The rational design of a gemcitabine prodrug with AIE-based intracellular light-up characteristics for selective suppression of pancreatic cancer cells

(5) Han, Haijie a Jin, Qiao a Wang, Yin a Chen, Yangjun a Ji, Jian a

a ZHEJIANG UNIVERSITY (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; CATHEPSIN B; ENZYME; GEMCITABINE; GLUTATHIONE; PRODRUG; TETRAPHENYLENE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BUTHIONINE SULFOXIMINE; CYSTEINE PROTEINASE INHIBITOR; DEOXYCYTIDINE; DIPEPTIDE; FLUORESCENT DYE; N-(3-PROPYLCARBAMOYLOXIRANE-2-CARBONYL)-ISOLEUCYL-PROLINE; S-ETHYL GLUTATHIONE; VITRONECTIN RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; CANCER INHIBITION; CANCER THERAPY; CELL VIABILITY; DISULFIDE BOND; DRUG DESIGN; FLUORESCENT LIGHTING; HYDROPHILICITY; INTERNALIZATION; PANCREAS CANCER; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CHEMISTRY; ENDOCYTOSIS; HUMAN; METABOLISM; OXIDATION REDUCTION REACTION; PANCREATIC NEOPLASMS; PHYSIOLOGY; SYNTHESIS; TUMOR CELL LINE;

AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; BUTHIONINE SULFOXIMINE; CATHEPSIN B; CELL LINE, TUMOR; CYSTEINE PROTEINASE INHIBITORS; DEOXYCYTIDINE; DIPEPTIDES; ENDOCYTOSIS; FLUORESCENT DYES; GLUTATHIONE; HUMANS; INTEGRIN ALPHAVBETA3; OXIDATION-REDUCTION; PANCREATIC NEOPLASMS; PRODRUGS;

EID: 84948798631 PISSN: 13597345 EISSN: 1364548X Source Type: Journal
DOI: 10.1039/c5cc06654a Document Type: Article

Times cited : (63)

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