The Murine Gammaherpesvirus Immediate-Early Rta Synergizes with IRF4, Targeting Expression of the Viral M1 Superantigen to Plasma Cells

PLoS Pathogens

Volumn 10, Issue 8, 2014, Pages

  O'Flaherty, Brigid M ^a   Soni, Tanushree ^a   Wakeman, Brian S ^a   Speck, Samuel H ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; IMMEDIATE EARLY PROTEIN; IMMEDIATE EARLY PROTEIN RTA; INTERFERON REGULATORY FACTOR 4; SUPERANTIGEN; SYNDECAN 1; UNCLASSIFIED DRUG; YELLOW FLUORESCENT PROTEIN; INTERFERON REGULATORY FACTOR; INTERFERON REGULATORY FACTOR-4; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; FEMALE; FLOW CYTOMETRY; GAMMAHERPESVIRINAE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; HERPES VIRUS INFECTION; HOST PARASITE INTERACTION; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; OPEN READING FRAME; PLASMA CELL; PLASMID; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSACTIVATION ASSAY; TRANSCRIPTION REGULATION; TRANSIENT TRANSFECTION; VIRUS LATENCY; VIRUS REACTIVATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; GENETICS; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; VIROLOGY; VIRUS ACTIVATION;

ANIMALS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; FLOW CYTOMETRY; GAMMAHERPESVIRINAE; GENE EXPRESSION REGULATION, VIRAL; HERPESVIRIDAE INFECTIONS; HOST-PARASITE INTERACTIONS; IMMEDIATE-EARLY PROTEINS; IMMUNOPRECIPITATION; INTERFERON REGULATORY FACTORS; MICE; MICE, INBRED C57BL; PLASMA CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPERANTIGENS; VIRAL PROTEINS; VIRUS ACTIVATION; VIRUS LATENCY;

EID: 84948697373     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004302     Document Type: Article

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