메뉴 건너뛰기




Volumn 3, Issue FEB, 2012, Pages

KSHV Rta promoter specification and viral reactivation

Author keywords

DNA binding; DNA protein interactions; Herpesvirus; KSHV; RBP JK; Reactivation; RTA

Indexed keywords


EID: 84874746003     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2012.00030     Document Type: Article
Times cited : (78)

References (150)
  • 1
    • 33646440294 scopus 로고    scopus 로고
    • Long-term-infected telomerase-immortalized endothelial cells: a model for Kaposis sarcoma-associated her-pesvirus latency in vitro and in vivo
    • An, F. Q., Folarin, H. M., Compitello, N., Roth, J., Gerson, S. L., Mccrae, K. R., Fakhari, F. D., Dittmer, D. P., and Renne, R. (2006). Long-term-infected telomerase-immortalized endothelial cells: a model for Kaposis sarcoma-associated her-pesvirus latency in vitro and in vivo. J. Virol. 80, 4833-4846.
    • (2006) J. Virol. , vol.80 , pp. 4833-4846
    • An, F.Q.1    Folarin, H.M.2    Compitello, N.3    Roth, J.4    Gerson, S.L.5    Mccrae, K.R.6    Fakhari, F.D.7    Dittmer, D.P.8    Renne, R.9
  • 2
    • 1242328736 scopus 로고    scopus 로고
    • Amplification of the Kaposis sarcoma-associated herpesvirus/human herpesvirus 8 lytic origin of DNA replication is dependent upon a cis-acting AT-rich region and an ORF50 response element and the trans-acting factors ORF50 (K-Rta) and K8 (K-bZIP)
    • AuCoin, D. P., Colletti, K. S., Cei, S. A., Papouskova, I., Tarrant, M., and Pari, G. S. (2004). Amplification of the Kaposis sarcoma-associated herpesvirus/human herpesvirus 8 lytic origin of DNA replication is dependent upon a cis-acting AT-rich region and an ORF50 response element and the trans-acting factors ORF50 (K-Rta) and K8 (K-bZIP). Virology 318, 542-555.
    • (2004) Virology , vol.318 , pp. 542-555
    • AuCoin, D.P.1    Colletti, K.S.2    Cei, S.A.3    Papouskova, I.4    Tarrant, M.5    Pari, G.S.6
  • 3
    • 0038523775 scopus 로고    scopus 로고
    • Host range of Kaposis sarcoma-associated her-pesvirus in cultured cells
    • Bechtel, J. T., Liang, Y., Hvidding, J., and Ganem, D. (2003). Host range of Kaposis sarcoma-associated her-pesvirus in cultured cells. J. Virol. 77, 6474-6481.
    • (2003) J. Virol. , vol.77 , pp. 6474-6481
    • Bechtel, J.T.1    Liang, Y.2    Hvidding, J.3    Ganem, D.4
  • 5
    • 80055064878 scopus 로고    scopus 로고
    • A viral nuclear non-coding RNA binds re-localized poly(A) binding protein and is required for late KSHV gene expression
    • doi:10.1371/journal.ppat.1002300
    • Borah, S., Darricarrere, N., Darnell, A., Myoung, J., and Steitz, J. A. (2011). A viral nuclear non-coding RNA binds re-localized poly(A) binding protein and is required for late KSHV gene expression. PLoS Pathog. 7, e1002300. doi:10.1371/journal.ppat.1002300
    • (2011) PLoS Pathog , vol.7
    • Borah, S.1    Darricarrere, N.2    Darnell, A.3    Myoung, J.4    Steitz, J.A.5
  • 7
    • 33646486990 scopus 로고    scopus 로고
    • Characterization of Kaposis sarcoma-associated herpesvirus (KSHV) K1 promoter activation by Rta
    • Bowser, B. S., Morris, S., Song, M. J., Sun, R., and Damania, B. (2006). Characterization of Kaposis sarcoma-associated herpesvirus (KSHV) K1 promoter activation by Rta. Virology 348, 309-327.
    • (2006) Virology , vol.348 , pp. 309-327
    • Bowser, B.S.1    Morris, S.2    Song, M.J.3    Sun, R.4    Damania, B.5
  • 8
    • 55449092922 scopus 로고    scopus 로고
    • Recruitment of the complete hTREX complex is required for Kaposis sarcoma-associated herpesvirus intron less mRNA nuclear export and virus replication
    • doi:10.1371/journal.ppat.1000194
    • Boyne, J. R., Colgan, K. J., and Whitehouse, A. (2008). Recruitment of the complete hTREX complex is required for Kaposis sarcoma-associated herpesvirus intron less mRNA nuclear export and virus replication. PLoS Pathog. 4, e1000194. doi:10.1371/journal.ppat.1000194
    • (2008) PLoS Pathog , vol.4
    • Boyne, J.R.1    Colgan, K.J.2    Whitehouse, A.3
  • 9
    • 77953123485 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus ORF57 protein interacts with PYM to enhance translation of viral intronless mRNAs
    • Boyne, J. R., Jackson, B. R., Taylor, A., Macnab, S. A., and Whitehouse, A. (2010a). Kaposis sarcoma-associated herpesvirus ORF57 protein interacts with PYM to enhance translation of viral intronless mRNAs. EMBO J. 29, 1851-1864.
    • (2010) EMBO J , vol.29 , pp. 1851-1864
    • Boyne, J.R.1    Jackson, B.R.2    Taylor, A.3    Macnab, S.A.4    Whitehouse, A.5
  • 10
    • 77956854995 scopus 로고    scopus 로고
    • ORF57: master regulator of KSHV mRNA biogenesis
    • Boyne, J. R., Jackson, B. R., and White-house, A. (2010b). ORF57: master regulator of KSHV mRNA biogenesis. Cell Cycle 9, 2702-2703.
    • (2010) Cell Cycle , vol.9 , pp. 2702-2703
    • Boyne, J.R.1    Jackson, B.R.2    White-House, A.3
  • 11
    • 0037770173 scopus 로고    scopus 로고
    • NF-kappaB inhibits gamma-herpesvirus lytic replication
    • Brown, H. J., Song, M. J., Deng, H., Wu, T. T., Cheng, G., and Sun, R. (2003). NF-kappaB inhibits gamma-herpesvirus lytic replication. J. Virol. 77, 8532-8540.
    • (2003) J. Virol. , vol.77 , pp. 8532-8540
    • Brown, H.J.1    Song, M.J.2    Deng, H.3    Wu, T.T.4    Cheng, G.5    Sun, R.6
  • 12
    • 34249826369 scopus 로고    scopus 로고
    • The Kaposis sarcoma-associated her-pesvirus/human herpesvirus-8 ORF50/Rta lytic switch protein functions as a tetramer
    • Bu, W., Carroll, K. D., Palmeri, D., and Lukac, D. M. (2007). The Kaposis sarcoma-associated her-pesvirus/human herpesvirus-8 ORF50/Rta lytic switch protein functions as a tetramer. J. Virol. 81, 5788-5806.
    • (2007) J. Virol. , vol.81 , pp. 5788-5806
    • Bu, W.1    Carroll, K.D.2    Palmeri, D.3    Lukac, D.M.4
  • 13
    • 55249092122 scopus 로고    scopus 로고
    • Identification of direct transcriptional targets of the KSHV Rta lytic switch protein by conditional nuclear localization
    • Bu,W., Palmeri, D., Krishnan, R., Marin, R., Aris,V. M., Soteropoulous, P., and Lukac, D. M. (2008). Identification of direct transcriptional targets of the KSHV Rta lytic switch protein by conditional nuclear localization. J. Virol. 82, 10709-10723.
    • (2008) J. Virol. , vol.82 , pp. 10709-10723
    • Bu, W.1    Palmeri, D.2    Krishnan, R.3    Marin, R.4    Aris, V.M.5    Soteropoulous, P.6    Lukac, D.M.7
  • 14
    • 80053997297 scopus 로고    scopus 로고
    • Construction of a lytically replicating Kaposis sarcoma-associated her-pesvirus
    • Budt, M., Hristozova, T., Hille, G., Berger, K., and Brune, W. (2011). Construction of a lytically replicating Kaposis sarcoma-associated her-pesvirus. J. Virol. 85, 10415-10420.
    • (2011) J. Virol. , vol.85 , pp. 10415-10420
    • Budt, M.1    Hristozova, T.2    Hille, G.3    Berger, K.4    Brune, W.5
  • 15
    • 17244375710 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells
    • Cai, X., Lu, S., Zhang, Z., Gonzalez, C. M., Damania, B., and Cullen, B. R. (2005). Kaposis sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proc. Natl. Acad. Sci. U.S.A.102, 5570-5575.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. 102 , pp. 5570-5575
    • Cai, X.1    Lu, S.2    Zhang, Z.3    Gonzalez, C.M.4    Damania, B.5    Cullen, B.R.6
  • 16
    • 30144437408 scopus 로고    scopus 로고
    • KSHV G protein-coupled receptor inhibits lytic gene transcription in primary-effusion lymphoma cells via p21-mediated inhibition of Cdk2
    • Cannon, M., Cesarman, E., and Boshoff, C. (2006). KSHV G protein-coupled receptor inhibits lytic gene transcription in primary-effusion lymphoma cells via p21-mediated inhibition of Cdk2. Blood 107, 277-284.
    • (2006) Blood , vol.107 , pp. 277-284
    • Cannon, M.1    Cesarman, E.2    Boshoff, C.3
  • 17
    • 33748935192 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus lytic switch protein stimulates DNA binding of RBP-Jk/CSL to activate the Notch pathway
    • Carroll, K. D., Bu, W., Palmeri, D., Spadavecchia, S., Lynch, S. J., Mar-ras, S. A., Tyagi, S., and Lukac, D.M. (2006). Kaposis sarcoma-associated herpesvirus lytic switch protein stimulates DNA binding of RBP-Jk/CSL to activate the Notch pathway. J. Virol. 80, 9697-9709.
    • (2006) J. Virol. , vol.80 , pp. 9697-9709
    • Carroll, K.D.1    Bu, W.2    Palmeri, D.3    Spadavecchia, S.4    Lynch, S.J.5    Marras, S.A.6    Tyagi, S.7    Lukac, D.M.8
  • 18
    • 34547765339 scopus 로고    scopus 로고
    • Direct interactions of KSHV/HHV-8 ORF50/Rta protein with the cellular protein Octamer-1 and DNA are critical for specifying transactivation of a delayed-early promoter and stimulating viral reactivation
    • Carroll, K. D., Khadim, F., Spadavec-chia, S., Palmeri, D., and Lukac, D. M. (2007). Direct interactions of KSHV/HHV-8 ORF50/Rta protein with the cellular protein Octamer-1 and DNA are critical for specifying transactivation of a delayed-early promoter and stimulating viral reactivation. J. Virol. 81, 8451-8467.
    • (2007) J. Virol. , vol.81 , pp. 8451-8467
    • Carroll, K.D.1    Khadim, F.2    Spadavec-Chia, S.3    Palmeri, D.4    Lukac, D.M.5
  • 19
    • 0029121668 scopus 로고
    • In vitro establishment and characterization of two acquired immunodeficiency syndrome-related lymphoma cell lines (BC-1 and BC-2) containing Kaposis sarcoma-associated herpesvirus-like (KSHV) DNA sequences
    • Cesarman, E., Moore, P. S., Rao, P. H., Inghirami, G., Knowles, D. M., and Chang, Y. (1995). In vitro establishment and characterization of two acquired immunodeficiency syndrome-related lymphoma cell lines (BC-1 and BC-2) containing Kaposis sarcoma-associated herpesvirus-like (KSHV) DNA sequences. Blood 86, 2708-2714.
    • (1995) Blood , vol.86 , pp. 2708-2714
    • Cesarman, E.1    Moore, P.S.2    Rao, P.H.3    Inghirami, G.4    Knowles, D.M.5    Chang, Y.6
  • 20
    • 77951996351 scopus 로고    scopus 로고
    • Array-based transcript profiling and limiting-dilution reverse transcription-PCR analysis identify additional latent genes in Kaposis sarcoma-associated herpesvirus
    • Chandriani, S., and Ganem, D. (2010). Array-based transcript profiling and limiting-dilution reverse transcription-PCR analysis identify additional latent genes in Kaposis sarcoma-associated herpesvirus. J. Virol. 84, 5565-5573.
    • (2010) J. Virol. , vol.84 , pp. 5565-5573
    • Chandriani, S.1    Ganem, D.2
  • 21
    • 77955006560 scopus 로고    scopus 로고
    • The lytic transcriptome of Kaposis sarcoma-associated her-pesvirus reveals extensive transcription of noncoding regions, including regions antisense to important genes
    • Chandriani, S., Xu, Y., and Ganem, D. (2010). The lytic transcriptome of Kaposis sarcoma-associated her-pesvirus reveals extensive transcription of noncoding regions, including regions antisense to important genes. J. Virol. 84, 7934-7942.
    • (2010) J. Virol. , vol.84 , pp. 7934-7942
    • Chandriani, S.1    Xu, Y.2    Ganem, D.3
  • 22
    • 27644526908 scopus 로고    scopus 로고
    • Role of Notch signal transduction in Kaposis sarcoma-associated her-pesvirus gene expression
    • Chang, H., Dittmer, D. P., Chul, S. Y., Hong, Y., and Jung, J. U. (2005a). Role of Notch signal transduction in Kaposis sarcoma-associated her-pesvirus gene expression. J. Virol. 79, 14371-14382.
    • (2005) J. Virol. , vol.79 , pp. 14371-14382
    • Chang, H.1    Dittmer, D.P.2    Chul, S.Y.3    Hong, Y.4    Jung, J.U.5
  • 24
    • 21644456373 scopus 로고    scopus 로고
    • Two subclasses of Kaposis sarcoma-associated herpesvirus lytic cycle promoters distinguished by open reading frame 50 mutant proteins that are deficient in binding to DNA
    • Chang, P. J., Shedd, D., and Miller, G. (2005c). Two subclasses of Kaposis sarcoma-associated herpesvirus lytic cycle promoters distinguished by open reading frame 50 mutant proteins that are deficient in binding to DNA. J. Virol. 79, 8750-8763.
    • (2005) J. Virol. , vol.79 , pp. 8750-8763
    • Chang, P.J.1    Shedd, D.2    Miller, G.3
  • 26
    • 67651007508 scopus 로고    scopus 로고
    • Kruppel-associated box domain-associated protein-1 as a latency regulator for Kaposis sarcoma-associated her-pesvirus and its modulation by the viral protein kinase
    • Chang, P. C., Fitzgerald, L. D., Van Gee-len, A., Izumiya, Y., Ellison, T. J., Wang, D. H., Ann, D. K., Luciw, P. A., and Kung, H. J. (2009). Kruppel-associated box domain-associated protein-1 as a latency regulator for Kaposis sarcoma-associated her-pesvirus and its modulation by the viral protein kinase. Cancer Res. 69, 5681-5689.
    • (2009) Cancer Res , vol.69 , pp. 5681-5689
    • Chang, P.C.1    Fitzgerald, L.D.2    Van Geelen, A.3    Izumiya, Y.4    Ellison, T.J.5    Wang, D.H.6    Ann, D.K.7    Luciw, P.A.8    Kung, H.J.9
  • 27
    • 75849147654 scopus 로고    scopus 로고
    • Binding of RBP-Jkappa (CSL) protein to the promoter of the Kaposis sarcoma-associated her-pesvirus ORF47 (gL) gene is a critical but not sufficient determinant of transactivation by ORF50 protein
    • Chang, P. J., Boonsiri, J., Wang, S. S., Chen, L. Y., and Miller, G. (2010). Binding of RBP-Jkappa (CSL) protein to the promoter of the Kaposis sarcoma-associated her-pesvirus ORF47 (gL) gene is a critical but not sufficient determinant of transactivation by ORF50 protein. Virology 398, 38-48.
    • (2010) Virology , vol.398 , pp. 38-48
    • Chang, P.J.1    Boonsiri, J.2    Wang, S.S.3    Chen, L.Y.4    Miller, G.5
  • 28
    • 4544383992 scopus 로고    scopus 로고
    • Autoregulation of DNA binding and protein stability of Kaposis sarcoma-associated herpesvirus ORF50 protein
    • Chang, P. J., and Miller, G. (2004). Autoregulation of DNA binding and protein stability of Kaposis sarcoma-associated herpesvirus ORF50 protein. J. Virol. 78, 10657-10673.
    • (2004) J. Virol. , vol.78 , pp. 10657-10673
    • Chang, P.J.1    Miller, G.2
  • 29
    • 0036121097 scopus 로고    scopus 로고
    • Open reading frame 50 protein of Kaposis sarcoma-associated her-pesvirus directly activates the viral PAN and K12 genes by binding to related response elements
    • Chang, P. J., Shedd, D., Gradoville, L., Cho, M. S., Chen, L. W., Chang, J., and Miller, G. (2002). Open reading frame 50 protein of Kaposis sarcoma-associated her-pesvirus directly activates the viral PAN and K12 genes by binding to related response elements. J. Virol. 76, 3168-3178.
    • (2002) J. Virol. , vol.76 , pp. 3168-3178
    • Chang, P.J.1    Shedd, D.2    Gradoville, L.3    Cho, M.S.4    Chen, L.W.5    Chang, J.6    Miller, G.7
  • 30
    • 52649124323 scopus 로고    scopus 로고
    • A mobile functional region of Kaposis sarcoma-associated her-pesvirus ORF50 protein independently regulates DNA binding and protein abundance
    • Chang, P. J., Shedd, D., and Miller, G. (2008). A mobile functional region of Kaposis sarcoma-associated her-pesvirus ORF50 protein independently regulates DNA binding and protein abundance. J. Virol. 82, 9700-9716.
    • (2008) J. Virol. , vol.82 , pp. 9700-9716
    • Chang, P.J.1    Shedd, D.2    Miller, G.3
  • 31
    • 84886949526 scopus 로고    scopus 로고
    • Merkel cell carcinoma: a virus-induced human cancer
    • Chang, Y., and Moore, P. S. (2011). Merkel cell carcinoma: a virus-induced human cancer. Annu. Rev. Pathol. PMID: 21942528. [Epub ahead of print].
    • (2011) Annu. Rev. Pathol
    • Chang, Y.1    Moore, P.S.2
  • 32
    • 0037112208 scopus 로고    scopus 로고
    • Viral IL-6-induced cell proliferation and immune evasion of interferon activity
    • Chatterjee, M., Osborne, J., Bestetti, G., Chang, Y., and Moore, P. S. (2002). Viral IL-6-induced cell proliferation and immune evasion of interferon activity. Science 298, 1432-1435.
    • (2002) Science , vol.298 , pp. 1432-1435
    • Chatterjee, M.1    Osborne, J.2    Bestetti, G.3    Chang, Y.4    Moore, P.S.5
  • 33
    • 0033850632 scopus 로고    scopus 로고
    • Transcriptional regulation of the Kaposis sarcoma-associated her-pesvirus viral interferon regulatory factor gene
    • Chen, J., Ueka, K., Sakakibara, S., Okuno,T.,and Yamanishi,K. (2000). Transcriptional regulation of the Kaposis sarcoma-associated her-pesvirus viral interferon regulatory factor gene. J. Virol. 74, 8623-8634.
    • (2000) J. Virol. , vol.74 , pp. 8623-8634
    • Chen, J.1    Ueka, K.2    Sakakibara, S.3    Okuno, T.4    Yamanishi, K.5
  • 34
    • 62749126635 scopus 로고    scopus 로고
    • Genome-wide identification of binding sites for Kaposis sarcoma-associated her-pesvirus lytic switch protein
    • Chen, J., Ye, F., Xie, J., Kuhne, K., and Gao, S. J. (2009). Genome-wide identification of binding sites for Kaposis sarcoma-associated her-pesvirus lytic switch protein, RTA. Virology 386, 290-302.
    • (2009) RTA. Virology , vol.386 , pp. 290-302
    • Chen, J.1    Ye, F.2    Xie, J.3    Kuhne, K.4    Gao, S.J.5
  • 35
    • 65449181607 scopus 로고    scopus 로고
    • Posttranscrip-tional gene regulation in Kaposis sarcoma-associated herpesvirus
    • Conrad, N. K. (2009). Posttranscrip-tional gene regulation in Kaposis sarcoma-associated herpesvirus. Adv. Appl. Microbiol. 68, 241-261.
    • (2009) Adv. Appl. Microbiol. , vol.68 , pp. 241-261
    • Conrad, N.K.1
  • 36
    • 2342589481 scopus 로고    scopus 로고
    • Comparison of the Rta/Orf50 transactivator proteins of gamma-2-herpesviruses
    • Damania, B., Jeong, J. H., Bowser, B. S., Dewire, S. M., Staudt, M. R., and Dittmer, D. P. (2004). Comparison of the Rta/Orf50 transactivator proteins of gamma-2-herpesviruses. J. Virol. 78, 5491-5499.
    • (2004) J. Virol. , vol.78 , pp. 5491-5499
    • Damania, B.1    Jeong, J.H.2    Bowser, B.S.3    Dewire, S.M.4    Staudt, M.R.5    Dittmer, D.P.6
  • 37
    • 0034532496 scopus 로고    scopus 로고
    • Auto-activation of the rta gene of human herpesvirus-8/Kaposis sarcoma-associated herpesvirus
    • Deng, H.,Young, A., and Sun, R. (2000). Auto-activation of the rta gene of human herpesvirus-8/Kaposis sarcoma-associated herpesvirus. J. Gen. Virol. 81, 3043-3048.
    • (2000) J. Gen. Virol. , vol.81 , pp. 3043-3048
    • Deng, H.1    Young, A.2    Sun, R.3
  • 38
    • 66149139159 scopus 로고    scopus 로고
    • Role of defective Oct-2 and OCA-B expression in immunoglobulin production and Kaposis sarcoma-associated her-pesvirus lytic reactivation in primary effusion lymphoma
    • Di Bartolo, D. L., Hyjek, E., Keller, S., Guasparri, I., Deng, H., Sun, R., Chadburn, A., Knowles, D. M., and Cesarman, E. (2009). Role of defective Oct-2 and OCA-B expression in immunoglobulin production and Kaposis sarcoma-associated her-pesvirus lytic reactivation in primary effusion lymphoma. J. Virol. 83, 4308-4315.
    • (2009) J. Virol. , vol.83 , pp. 4308-4315
    • Di Bartolo, D.L.1    Hyjek, E.2    Keller, S.3    Guasparri, I.4    Deng, H.5    Sun, R.6    Chadburn, A.7    Knowles, D.M.8    Cesarman, E.9
  • 39
    • 0031713755 scopus 로고    scopus 로고
    • Lymphoma cell lines: in vitro models for the study of HHV-8+ primary effusion lymphomas (body cavity-based lymhomas)
    • Drexler, H., Uphoff, C., Gaidano, G., and Carbone, A. (1998). Lymphoma cell lines: in vitro models for the study of HHV-8+ primary effusion lymphomas (body cavity-based lymhomas). Leukemia 12, 1507-1517.
    • (1998) Leukemia , vol.12 , pp. 1507-1517
    • Drexler, H.1    Uphoff, C.2    Gaidano, G.3    Carbone, A.4
  • 40
    • 0035095932 scopus 로고    scopus 로고
    • Characterization of Kaposis sarcoma-associated herpesvirus/human herpesvirus-8 ORF57 promoter
    • Duan, W., Wang, S., Liu, S., and Wood, C. (2001). Characterization of Kaposis sarcoma-associated herpesvirus/human herpesvirus-8 ORF57 promoter. Arch. Virol. 146, 403-413.
    • (2001) Arch. Virol. , vol.146 , pp. 403-413
    • Duan, W.1    Wang, S.2    Liu, S.3    Wood, C.4
  • 41
    • 63549108515 scopus 로고    scopus 로고
    • A comprehensive analysis of recruitment and transactivation potential of K-Rta and K-bZIP during reactivation of Kaposis sarcoma-associated herpesvirus
    • Ellison, T. J., Izumiya, Y., Izumiya, C., Luciw, P. A., and Kung, H. J. (2009). A comprehensive analysis of recruitment and transactivation potential of K-Rta and K-bZIP during reactivation of Kaposis sarcoma-associated herpesvirus. Virology 387, 76-88.
    • (2009) Virology , vol.387 , pp. 76-88
    • Ellison, T.J.1    Izumiya, Y.2    Izumiya, C.3    Luciw, P.A.4    Kung, H.J.5
  • 42
    • 0036100266 scopus 로고    scopus 로고
    • Charting latency transcripts in Kaposis sarcoma-associated her-pesvirus by whole-genome realtime quantitative PCR
    • Fakhari, F. D., and Dittmer, D. P. (2002). Charting latency transcripts in Kaposis sarcoma-associated her-pesvirus by whole-genome realtime quantitative PCR. J. Virol. 76, 6213-6223.
    • (2002) J. Virol. , vol.76 , pp. 6213-6223
    • Fakhari, F.D.1    Dittmer, D.P.2
  • 43
    • 35348962397 scopus 로고    scopus 로고
    • eds D. M. Knipe and P. M. Howley (Philadelphia: Lippincott Williams and Wilkins)
    • Ganem, D. (2007). Kaposis sarcoma-associated herpesvirus, in Fields Virology, eds D. M. Knipe and P. M. Howley (Philadelphia: Lippincott Williams and Wilkins), 2848-2888.
    • (2007) Kaposis sarcoma-associated herpesvirus, in Fields Virology , pp. 2848-2888
    • Ganem, D.1
  • 44
    • 0034083471 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus open reading frame 50/Rta protein activates the entire lytic cycle in the HH-B2 primary effusion lymphoma cell line
    • Gradoville, L., Gerlach, J., Grogan, E., Shedd, D., Nikiforow, S., Metroka, C., and Miller, G. (2000). Kaposis sarcoma-associated herpesvirus open reading frame 50/Rta protein activates the entire lytic cycle in the HH-B2 primary effusion lymphoma cell line. J. Virol. 74, 6207-6212.
    • (2000) J. Virol. , vol.74 , pp. 6207-6212
    • Gradoville, L.1    Gerlach, J.2    Grogan, E.3    Shedd, D.4    Nikiforow, S.5    Metroka, C.6    Miller, G.7
  • 45
    • 1542571327 scopus 로고    scopus 로고
    • Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis
    • Grundhoff, A., and Ganem, D. (2004). Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis. J. Clin. Invest. 113, 124-136.
    • (2004) J. Clin. Invest. , vol.113 , pp. 124-136
    • Grundhoff, A.1    Ganem, D.2
  • 46
    • 77954688337 scopus 로고    scopus 로고
    • The epigenetic landscape of latent Kaposi sarcoma-associated herpesvirus genomes
    • doi:10.1371/journal.ppat.1000935
    • Gunther, T., and Grundhoff, A. (2010). The epigenetic landscape of latent Kaposi sarcoma-associated herpesvirus genomes. PLoS Pathog. 6, e1000935. doi:10.1371/journal.ppat.1000935
    • (2010) PLoS Pathog , vol.6
    • Gunther, T.1    Grundhoff, A.2
  • 47
    • 0033986420 scopus 로고    scopus 로고
    • The human herpesvirus 8 homolog of Epstein-Barr virus SM protein (KS-SM) is a posttranscriptional activator of gene expression
    • Gupta, A. K., Ruvolo, V., Patterson, C., and Swaminathan, S. (2000). The human herpesvirus 8 homolog of Epstein-Barr virus SM protein (KS-SM) is a posttranscriptional activator of gene expression. J. Virol. 74, 1038-1044.
    • (2000) J. Virol. , vol.74 , pp. 1038-1044
    • Gupta, A.K.1    Ruvolo, V.2    Patterson, C.3    Swaminathan, S.4
  • 48
    • 0034990504 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus open reading frame 50 represses p53-induced transcriptional activity and apopto-sis
    • Gwack, Y., Hwang, S., Byun, H., Lim, C., Kim, J. W., Choi, E. J., and Choe, J. (2001). Kaposis sarcoma-associated herpesvirus open reading frame 50 represses p53-induced transcriptional activity and apopto-sis. J. Virol. 75, 6245-6248.
    • (2001) J. Virol. , vol.75 , pp. 6245-6248
    • Gwack, Y.1    Hwang, S.2    Byun, H.3    Lim, C.4    Kim, J.W.5    Choi, E.J.6    Choe, J.7
  • 49
    • 0037155143 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus open reading frame 50 stimulates the transcriptional activity of STAT3
    • Gwack, Y., Hwang, S., Lim, C., Won, Y. S., Lee, C. H., and Choe, J. (2002). Kaposis sarcoma-associated herpesvirus open reading frame 50 stimulates the transcriptional activity of STAT3. J. Biol. Chem. 277, 6438-6442.
    • (2002) J. Biol. Chem. , vol.277 , pp. 6438-6442
    • Gwack, Y.1    Hwang, S.2    Lim, C.3    Won, Y.S.4    Lee, C.H.5    Choe, J.6
  • 50
    • 0242412242 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase 1 and Ste20-like kinase hKFC act as tran-scriptional repressors for gamma-2 herpesvirus lytic replication
    • Gwack, Y., Nakamura, H., Lee, S. H., Souvlis, J., Yustein, J. T., Gygi, S., Kung, H. J., and Jung, J. U. (2003). Poly(ADP-ribose) polymerase 1 and Ste20-like kinase hKFC act as tran-scriptional repressors for gamma-2 herpesvirus lytic replication. Mol. Cell. Biol. 23, 8282-8294.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 8282-8294
    • Gwack, Y.1    Nakamura, H.2    Lee, S.H.3    Souvlis, J.4    Yustein, J.T.5    Gygi, S.6    Kung, H.J.7    Jung, J.U.8
  • 51
    • 33646735179 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated her-pesvirus lytic gene ORF57isessential for infectious virion production
    • Han, Z., and Swaminathan, S. (2006). Kaposis sarcoma-associated her-pesvirus lytic gene ORF57isessential for infectious virion production. J. Virol. 80, 5251-5260.
    • (2006) J. Virol. , vol.80 , pp. 5251-5260
    • Han, Z.1    Swaminathan, S.2
  • 52
    • 49649111581 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus (KSHV) Rta and cellular HMGB1 proteins syner-gistically transactivate the KSHV ORF50 promoter
    • Harrison, S. M., and Whitehouse, A. (2008). Kaposis sarcoma-associated herpesvirus (KSHV) Rta and cellular HMGB1 proteins syner-gistically transactivate the KSHV ORF50 promoter. FEBS Lett. 582, 3080-3084.
    • (2008) FEBS Lett , vol.582 , pp. 3080-3084
    • Harrison, S.M.1    Whitehouse, A.2
  • 53
    • 75449113080 scopus 로고    scopus 로고
    • Cellular corepressor TLE2 inhibits replication-and-transcription-activator-mediated transactivation and lytic reactivation of Kaposis sarcoma-associated herpesvirus
    • He, Z., Liu, Y., Liang, D., Wang, Z., Robertson, E. S., and Lan, K. (2010). Cellular corepressor TLE2 inhibits replication-and-transcription-activator-mediated transactivation and lytic reactivation of Kaposis sarcoma-associated herpesvirus. J. Virol. 84, 2047-2062.
    • (2010) J. Virol. , vol.84 , pp. 2047-2062
    • He, Z.1    Liu, Y.2    Liang, D.3    Wang, Z.4    Robertson, E.S.5    Lan, K.6
  • 54
    • 66149112412 scopus 로고    scopus 로고
    • NF-kappaB serves as a cellular sensor of Kaposis sarcoma-associated herpesvirus latency and negatively regulates K-Rta by antagonizing the RBP-Jkappa coactivator
    • Izumiya, Y., Izumiya, C., Hsia, D., Ellison, T. J., Luciw, P. A., and Kung, H. J. (2009). NF-kappaB serves as a cellular sensor of Kaposis sarcoma-associated herpesvirus latency and negatively regulates K-Rta by antagonizing the RBP-Jkappa coactivator. J. Virol. 83, 4435-4446.
    • (2009) J. Virol. , vol.83 , pp. 4435-4446
    • Izumiya, Y.1    Izumiya, C.2    Hsia, D.3    Ellison, T.J.4    Luciw, P.A.5    Kung, H.J.6
  • 56
    • 0035167125 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus latent and lytic gene expression as revealed by DNA arrays.
    • Jenner, R., Alba, M., Boshoff, C., and Kellam, P. (2001). Kaposis sarcoma-associated herpesvirus latent and lytic gene expression as revealed by DNA arrays. J. Virol. 75, 891-902.
    • (2001) J. Virol. , vol.75 , pp. 891-902
    • Jenner, R.1    Alba, M.2    Boshoff, C.3    Kellam, P.4
  • 57
    • 80052336129 scopus 로고    scopus 로고
    • Coordination of KSHV latent and lytic gene control by CTCF-cohesin mediated chromosome conformation
    • doi:10.1371/journal.ppat.1002140
    • Kang, H., Wiedmer, A., Yuan, Y., Robertson, E., and Lieberman, P. M. (2011a). Coordination of KSHV latent and lytic gene control by CTCF-cohesin mediated chromosome conformation. PLoS Pathog. 7, e1002140. doi:10.1371/journal.ppat.1002140
    • (2011) PLoS Pathog , vol.7
    • Kang, H.1    Wiedmer, A.2    Yuan, Y.3    Robertson, E.4    Lieberman, P.M.5
  • 58
    • 79952386909 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated her-pesvirus ORF57 promotes escape of viral and human interleukin-6 from microRNA-mediated suppression.
    • Kang, J. G., Pripuzova, N., Majer-ciak, V., Kruhlak, M., Le, S. Y., and Zheng, Z. M. (2011b). Kaposis sarcoma-associated her-pesvirus ORF57 promotes escape of viral and human interleukin-6 from microRNA-mediated suppression. J. Virol. 85, 2620-2630.
    • (2011) J. Virol. , vol.85 , pp. 2620-2630
    • Kang, J.G.1    Pripuzova, N.2    Majer-Ciak, V.3    Kruhlak, M.4    Le, S.Y.5    Zheng, Z.M.6
  • 59
    • 37049006758 scopus 로고    scopus 로고
    • Overex-pression of the kaposis sarcoma-associated herpesvirus transactiva-tor K-Rta can complement a K-bZIP deletion BACmid and yields an enhanced growth phenotype
    • Kato-Noah, T., Xu, Y., Rossetto, C. C., Colletti, K., Papouskova, I., and Pari, G. S. (2007). Overex-pression of the kaposis sarcoma-associated herpesvirus transactiva-tor K-Rta can complement a K-bZIP deletion BACmid and yields an enhanced growth phenotype. J. Virol. 81, 13519-13532.
    • (2007) J. Virol. , vol.81 , pp. 13519-13532
    • Kato-Noah, T.1    Xu, Y.2    Rossetto, C.C.3    Colletti, K.4    Papouskova, I.5    Pari, G.S.6
  • 60
    • 0000942113 scopus 로고    scopus 로고
    • 5th Edn. eds D. M. Knipe and P. M. How-ley (Philadelphia, PA: Lippincott Williams and Wilkins)
    • Kieff, E., and Rickinson, A. (2007). Epstein-barr virus and its replication, in Fields Virology, 5th Edn. eds D. M. Knipe and P. M. How-ley (Philadelphia, PA: Lippincott Williams and Wilkins), 2603-2654.
    • (2007) Epstein-barr virus and its replication, in Fields Virology , pp. 2603-2654
    • Kieff, E.1    Rickinson, A.2
  • 61
    • 0034076058 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus open reading frame 57 encodes a posttranscriptional regulator with multiple distinct activities
    • Kirshner, J. R., Lukac, D. M., Chang, J., and Ganem, D. (2000). Kaposis sarcoma-associated herpesvirus open reading frame 57 encodes a posttranscriptional regulator with multiple distinct activities. J. Virol. 74, 3586-3597.
    • (2000) J. Virol. , vol.74 , pp. 3586-3597
    • Kirshner, J.R.1    Lukac, D.M.2    Chang, J.3    Ganem, D.4
  • 62
    • 0033030061 scopus 로고    scopus 로고
    • Expression of the open reading frame 74 (G-protein-coupled receptor) gene of Kaposis sarcoma (KS)-associated herpesvirus; implications for KS pathogenesis
    • Kirshner, J. R., Staskus, K., Haase, A., Lagunoff, M.,and Ganem, D. (1999). Expression of the open reading frame 74 (G-protein-coupled receptor) gene of Kaposis sarcoma (KS)-associated herpesvirus; implications for KS pathogenesis. J. Virol. 73, 6006-6014.
    • (1999) J. Virol. , vol.73 , pp. 6006-6014
    • Kirshner, J.R.1    Staskus, K.2    Haase, A.3    Lagunoff, M.4    Ganem, D.5
  • 63
    • 14744269431 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus reactivation is regulated by interaction of latency-associated nuclear antigen with recombination signal sequence-binding protein Jkappa, the major downstream effector of the Notch signaling pathway
    • Lan, K., Kuppers, D. A., and Robertson, E. S. (2005a). Kaposis sarcoma-associated herpesvirus reactivation is regulated by interaction of latency-associated nuclear antigen with recombination signal sequence-binding protein Jkappa, the major downstream effector of the Notch signaling pathway. J. Virol. 79, 3468-3478.
    • (2005) J. Virol. , vol.79 , pp. 3468-3478
    • Lan, K.1    Kuppers, D.A.2    Robertson, E.S.3
  • 64
    • 19944370134 scopus 로고    scopus 로고
    • Induction of Kaposis sarcoma-associated her-pesvirus latency-associated nuclear antigen by the lytic transactivator RTA: a novel mechanism for establishment of latency
    • Lan, K., Kuppers, D. A., Verma, S. C., Sharma, N., Murakami, M., and Robertson, E. S. (2005b). Induction of Kaposis sarcoma-associated her-pesvirus latency-associated nuclear antigen by the lytic transactivator RTA: a novel mechanism for establishment of latency. J. Virol. 79, 7453-7465.
    • (2005) J. Virol. , vol.79 , pp. 7453-7465
    • Lan, K.1    Kuppers, D.A.2    Verma, S.C.3    Sharma, N.4    Murakami, M.5    Robertson, E.S.6
  • 65
    • 2642586357 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen inhibits lytic replication by targeting Rta: a potential mechanism for virus-mediated control of latency
    • Lan, K., Kuppers, D. A., Verma, S. C., and Robertson,E. S. (2004). Kaposis sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen inhibits lytic replication by targeting Rta: a potential mechanism for virus-mediated control of latency. J. Virol. 78, 6585-6594.
    • (2004) J. Virol. , vol.78 , pp. 6585-6594
    • Lan, K.1    Kuppers, D.A.2    Verma, S.C.3    Robertson, E.S.4
  • 66
    • 0036682519 scopus 로고    scopus 로고
    • The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jk, the target of the Notch signaling pathway
    • Liang, Y., Chang, J., Lynch, S., Lukac, D. M., and Ganem, D. (2002). The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jk, the target of the Notch signaling pathway. Genes Dev. 16, 1977-1989.
    • (2002) Genes Dev , vol.16 , pp. 1977-1989
    • Liang, Y.1    Chang, J.2    Lynch, S.3    Lukac, D.M.4    Ganem, D.5
  • 67
    • 0037477789 scopus 로고    scopus 로고
    • Lytic but not latent infection by Kaposis sarcoma-associated her-pesvirus requires host CSL protein, the mediator of Notch signaling
    • Liang, Y., and Ganem, D. (2003). Lytic but not latent infection by Kaposis sarcoma-associated her-pesvirus requires host CSL protein, the mediator of Notch signaling. Proc. Natl. Acad. Sci. U.S.A. 100, 8490-8495.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 8490-8495
    • Liang, Y.1    Ganem, D.2
  • 68
    • 2942667699 scopus 로고    scopus 로고
    • RBP-J (CSL) is essential for activation of the K14/vGPCR promoter of Kaposis sarcoma-associated her-pesvirus by the lytic switch protein RTA
    • Liang, Y., and Ganem, D. (2004). RBP-J (CSL) is essential for activation of the K14/vGPCR promoter of Kaposis sarcoma-associated her-pesvirus by the lytic switch protein RTA. J. Virol. 78, 6818-6826.
    • (2004) J. Virol. , vol.78 , pp. 6818-6826
    • Liang, Y.1    Ganem, D.2
  • 69
    • 0042890398 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus/human her-pesvirus 8 transcriptional activator Rta is an oligomeric DNA-binding protein that interacts with tandem arrays of phased A/T-trinucleotide motifs
    • Liao, W., Tang, Y., Kuo, Y. L., Liu, B.Y., Xu, C. J., and Giam, C.Z. (2003a). Kaposis sarcoma-associated herpesvirus/human her-pesvirus 8 transcriptional activator Rta is an oligomeric DNA-binding protein that interacts with tandem arrays of phased A/T-trinucleotide motifs. J. Virol. 77, 9399-9411.
    • (2003) J. Virol. , vol.77 , pp. 9399-9411
    • Liao, W.1    Tang, Y.2    Kuo, Y.L.3    Liu, B.Y.4    Xu, C.J.5    Giam, C.Z.6
  • 70
    • 0037333854 scopus 로고    scopus 로고
    • K-bZIP of Kaposis sarcoma-associated herpesvirus/human herpesvirus 8 (KSHV/HHV-8) binds KSHV/HHV-8 Rta and represses Rta-mediated transactivation
    • Liao, W., Tang, Y., Lin, S. F., Kung, H. J., and Giam, C. Z. (2003b). K-bZIP of Kaposis sarcoma-associated herpesvirus/human herpesvirus 8 (KSHV/HHV-8) binds KSHV/HHV-8 Rta and represses Rta-mediated transactivation. J. Virol. 77, 3809-3815.
    • (2003) J. Virol. , vol.77 , pp. 3809-3815
    • Liao, W.1    Tang, Y.2    Lin, S.F.3    Kung, H.J.4    Giam, C.Z.5
  • 71
    • 53249107181 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus RTA activates the pro-cessivity factor ORF59 through interaction with RBP-Jkappa and a cis-acting RTA responsive element
    • Liu, Y., Cao, Y., Liang, D., Gao, Y., Xia, T., Robertson, E. S., and Lan, K. (2008). Kaposis sarcoma-associated herpesvirus RTA activates the pro-cessivity factor ORF59 through interaction with RBP-Jkappa and a cis-acting RTA responsive element. Virology 380, 264-275.
    • (2008) Virology , vol.380 , pp. 264-275
    • Liu, Y.1    Cao, Y.2    Liang, D.3    Gao, Y.4    Xia, T.5    Robertson, E.S.6    Lan, K.7
  • 72
    • 10044265682 scopus 로고    scopus 로고
    • Dissection of the Kaposis sarcoma-associated her-pesvirus gene expression program by using the viral DNA replication inhibitor cidofovir
    • Lu, M., Suen, J., Frias, C., Pfeiffer, R., Tsai, M. H., Chuang, E., and Zeichner, S. L. (2004). Dissection of the Kaposis sarcoma-associated her-pesvirus gene expression program by using the viral DNA replication inhibitor cidofovir. J. Virol. 78, 13637-13652.
    • (2004) J. Virol. , vol.78 , pp. 13637-13652
    • Lu, M.1    Suen, J.2    Frias, C.3    Pfeiffer, R.4    Tsai, M.H.5    Chuang, E.6    Zeichner, S.L.7
  • 73
    • 0034953721 scopus 로고    scopus 로고
    • DNA binding by the Kaposis sarcoma-associated herpesvirus lytic switch protein is necessary for tran-scriptional activation of two viral delayed early promoters
    • Lukac, D., Garibyan, L., Kirshner, J., Palmeri, D., and Ganem, D. (2001). DNA binding by the Kaposis sarcoma-associated herpesvirus lytic switch protein is necessary for tran-scriptional activation of two viral delayed early promoters. J. Virol. 75, 6786-6799.
    • (2001) J. Virol. , vol.75 , pp. 6786-6799
    • Lukac, D.1    Garibyan, L.2    Kirshner, J.3    Palmeri, D.4    Ganem, D.5
  • 74
    • 0032830320 scopus 로고    scopus 로고
    • Transcriptional activation by the product of open reading frame 50 of Kaposis sarcoma-associated herpesvirus is required for lytic viral reactivation in B cells
    • Lukac, D. M., Kirshner, J. R., and Ganem, D. (1999). Transcriptional activation by the product of open reading frame 50 of Kaposis sarcoma-associated herpesvirus is required for lytic viral reactivation in B cells. J. Virol. 73, 9348-9361.
    • (1999) J. Virol. , vol.73 , pp. 9348-9361
    • Lukac, D.M.1    Kirshner, J.R.2    Ganem, D.3
  • 75
    • 0032567394 scopus 로고    scopus 로고
    • Reactivation of Kaposis sarcoma-associated herpesvirus infection from latency by expression of the ORF 50 transactivator, a homolog of the EBV R protein
    • Lukac, D. M., Renne, R., Kirshner, J. R., and Ganem, D. (1998). Reactivation of Kaposis sarcoma-associated herpesvirus infection from latency by expression of the ORF 50 transactivator, a homolog of the EBV R protein. Virology 252, 304-312.
    • (1998) Virology , vol.252 , pp. 304-312
    • Lukac, D.M.1    Renne, R.2    Kirshner, J.R.3    Ganem, D.4
  • 76
    • 33846547953 scopus 로고    scopus 로고
    • Targeted disruption of KSHV ORF57 in the viral genome is detrimental for the expression of ORF59, K8{alpha}, and K8. 1 and the production of infectious virus
    • Majerciak, V., Pripuzova, N., Mccoy, J. P., Gao, S. J., and Zheng, Z. M. (2006a). Targeted disruption of KSHV ORF57 in the viral genome is detrimental for the expression of ORF59, K8{alpha}, and K8.1 and the production of infectious virus. J. Virol. 81, 1062-1071.
    • (2006) J. Virol. , vol.81 , pp. 1062-1071
    • Majerciak, V.1    Pripuzova, N.2    Mccoy, J.P.3    Gao, S.J.4    Zheng, Z.M.5
  • 77
    • 33748788787 scopus 로고    scopus 로고
    • Structural and functional analyses of Kaposi sarcoma-associated her-pesvirus ORF57 nuclear localization signals in living cells
    • Majerciak, V., Yamanegi, K., Nie, S. H., and Zheng, Z. M. (2006b). Structural and functional analyses of Kaposi sarcoma-associated her-pesvirus ORF57 nuclear localization signals in living cells. J. Biol. Chem. 281, 28365-28378.
    • (2006) J. Biol. Chem. , vol.281 , pp. 28365-28378
    • Majerciak, V.1    Yamanegi, K.2    Nie, S.H.3    Zheng, Z.M.4
  • 78
    • 33845423990 scopus 로고    scopus 로고
    • Gene structure and expression of Kaposis sarcoma-associated herpesvirus ORF56, ORF57, ORF58, and ORF59
    • Majerciak, V., Yamanegi, K., and Zheng, Z. M. (2006c). Gene structure and expression of Kaposis sarcoma-associated herpesvirus ORF56, ORF57, ORF58, and ORF59. J. Virol. 80, 11968-11981.
    • (2006) J. Virol. , vol.80 , pp. 11968-11981
    • Majerciak, V.1    Yamanegi, K.2    Zheng, Z.M.3
  • 79
    • 33846547953 scopus 로고    scopus 로고
    • Targeted disruption of Kaposis sarcoma-associated her-pesvirus ORF57 in the viral genome is detrimental for the expression of ORF59, K8alpha, and K8. 1 and the production of infectious virus
    • Majerciak, V., Pripuzova, N., Mccoy, J. P., Gao, S. J., and Zheng, Z. M. (2007). Targeted disruption of Kaposis sarcoma-associated her-pesvirus ORF57 in the viral genome is detrimental for the expression of ORF59, K8alpha, and K8.1 and the production of infectious virus. J. Virol. 81, 1062-1071.
    • (2007) J. Virol. , vol.81 , pp. 1062-1071
    • Majerciak, V.1    Pripuzova, N.2    Mccoy, J.P.3    Gao, S.J.4    Zheng, Z.M.5
  • 80
    • 78951490537 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus ORF57 interacts with cellular RNA export cofac-tors RBM15 and OTT3 to promote expression of viral ORF59
    • Majerciak, V., Uranishi, H., Kruh-lak, M., Pilkington, G. R., Mas-simelli, M. J., Bear, J., Pavlakis, G. N., Felber, B. K., and Zheng, Z. M. (2011). Kaposis sarcoma-associated herpesvirus ORF57 interacts with cellular RNA export cofac-tors RBM15 and OTT3 to promote expression of viral ORF59. J. Virol. 85, 1528-1540.
    • (2011) J. Virol. , vol.85 , pp. 1528-1540
    • Majerciak, V.1    Uranishi, H.2    Kruhlak, M.3    Pilkington, G.R.4    Massimelli, M.J.5    Bear, J.6    Pavlakis, G.N.7    Felber, B.K.8    Zheng, Z.M.9
  • 81
    • 40149095094 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated her-pesvirus ORF57 functions as a viral splicing factor and promotes expression of intron-containing viral lytic genes in spliceosome-mediated RNA splicing
    • Majerciak, V., Yamanegi, K., Alle-mand, E., Kruhlak, M., Krainer, A.R., and Zheng, Z. M. (2008). Kaposis sarcoma-associated her-pesvirus ORF57 functions as a viral splicing factor and promotes expression of intron-containing viral lytic genes in spliceosome-mediated RNA splicing. J. Virol. 82, 2792-2801.
    • (2008) J. Virol. , vol.82 , pp. 2792-2801
    • Majerciak, V.1    Yamanegi, K.2    Allemand, E.3    Kruhlak, M.4    Krainer, A.R.5    Zheng, Z.M.6
  • 82
    • 63849102197 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated her-pesvirus ORF57 in viral RNA processing
    • Majerciak, V., and Zheng, Z. M. (2009). Kaposis sarcoma-associated her-pesvirus ORF57 in viral RNA processing. Front. Biosci. 14, 1516-1528.
    • (2009) Front. Biosci. , vol.14 , pp. 1516-1528
    • Majerciak, V.1    Zheng, Z.M.2
  • 83
    • 4043147875 scopus 로고    scopus 로고
    • Functional co-operation between the Kaposis sarcoma-associated herpesvirus ORF57 and ORF50 regulatory proteins
    • Malik, P., Blackbourn, D. J., Cheng, M. F., Hayward, G. S., and Clements, J. B (2004a). Functional co-operation between the Kaposis sarcoma-associated herpesvirus ORF57 and ORF50 regulatory proteins. J. Gen. Virol. 85, 2155-2166.
    • (2004) J. Gen. Virol. , vol.85 , pp. 2155-2166
    • Malik, P.1    Blackbourn, D.J.2    Cheng, M.F.3    Hayward, G.S.4    Clements, J.B.5
  • 84
    • 3542999242 scopus 로고    scopus 로고
    • The evo-lutionarily conserved Kaposis sarcoma-associated herpesvirus ORF57 protein interacts with REF protein and acts as an RNA export factor
    • Malik, P., Blackbourn, D. J., and Clements, J. B. (2004b). The evo-lutionarily conserved Kaposis sarcoma-associated herpesvirus ORF57 protein interacts with REF protein and acts as an RNA export factor. J. Biol. Chem. 279, 33001-33011.
    • (2004) J. Biol. Chem. , vol.279 , pp. 33001-33011
    • Malik, P.1    Blackbourn, D.J.2    Clements, J.B.3
  • 85
    • 72949087815 scopus 로고    scopus 로고
    • Human tumor-associated viruses and new insights into the molecular mechanisms of cancer
    • Martin, D., and Gutkind, J. S. (2008). Human tumor-associated viruses and new insights into the molecular mechanisms of cancer. Oncogene 27(Suppl. 2), S31-S42.
    • (2008) Oncogene , vol.27 , Issue.SUPPL. 2
    • Martin, D.1    Gutkind, J.S.2
  • 86
    • 80054796475 scopus 로고    scopus 로고
    • Stability of a long noncoding viral RNA depends on a 9-nt core element at the RNA 5 end to interact with viral ORF57 and cellular PABPC1
    • Massimelli, M. J., Kang, J. G., Majerciak, V., Le, S. Y., Liewehr, D. J., Steinberg, S. M., and Zheng, Z. M. (2011). Stability of a long noncoding viral RNA depends on a 9-nt core element at the RNA 5 end to interact with viral ORF57 and cellular PABPC1. Int. J. Biol Sci. 7,1145-1160.
    • (2011) Int. J. Biol Sci. , vol.7 , pp. 1145-1160
    • Massimelli, M.J.1    Kang, J.G.2    Majerciak, V.3    Le, S.Y.4    Liewehr, D.J.5    Steinberg, S.M.6    Zheng, Z.M.7
  • 87
    • 77957121811 scopus 로고    scopus 로고
    • Kaposis sarcoma and its associated herpesvirus
    • Mesri, E. A., Cesarman, E., and Boshoff, C. (2010). Kaposis sarcoma and its associated herpesvirus. Nat. Rev. Cancer 10, 707-719.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 707-719
    • Mesri, E.A.1    Cesarman, E.2    Boshoff, C.3
  • 88
    • 77954955259 scopus 로고    scopus 로고
    • Human papillomavirus oncoproteins: pathways to transformation
    • Moody, C. A.,and Laimins,L.A. (2010). Human papillomavirus oncoproteins: pathways to transformation. Nat. Rev. Cancer 10, 550-560.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 550-560
    • Moody, C.A.1    Laimins, L.A.2
  • 90
    • 0037377723 scopus 로고    scopus 로고
    • Global changes in Kaposis sarcoma-associated virus gene expression patterns following expression of a tetracycline-inducible Rta transactivator
    • Nakamura, H., Lu, M., Gwack, Y., Sou-vlis, J., Zeichner, S. L., and Jung, J. U. (2003). Global changes in Kaposis sarcoma-associated virus gene expression patterns following expression of a tetracycline-inducible Rta transactivator. J. Virol 77, 4205-4220.
    • (2003) J. Virol , vol.77 , pp. 4205-4220
    • Nakamura, H.1    Lu, M.2    Gwack, Y.3    Souvlis, J.4    Zeichner, S.L.5    Jung, J.U.6
  • 91
    • 35348914370 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus ORF57 protein enhances mRNA accumulation independently of effects on nuclear RNA export
    • Nekorchuk, M., Han, Z., Hsieh, T. T., and Swaminathan, S. (2007). Kaposis sarcoma-associated herpesvirus ORF57 protein enhances mRNA accumulation independently of effects on nuclear RNA export. J. Virol 81,9990-9998.
    • (2007) J. Virol , vol.81 , pp. 9990-9998
    • Nekorchuk, M.1    Han, Z.2    Hsieh, T.T.3    Swaminathan, S.4
  • 92
    • 3142688963 scopus 로고    scopus 로고
    • A posttranscriptional regulator of Kaposis sarcoma-associated herpesvirus interacts with RNA-binding protein PCBP1 and controls gene expression through the IRES
    • Nishimura, K., Ueda, K., Guwanan, E., Sakakibara, S., Do, E., Osaki, E., Yada, K., Okuno, T., and Yamanishi, K. (2004). A posttranscriptional regulator of Kaposis sarcoma-associated herpesvirus interacts with RNA-binding protein PCBP1 and controls gene expression through the IRES. Virology 325, 364-378.
    • (2004) Virology , vol.325 , pp. 364-378
    • Nishimura, K.1    Ueda, K.2    Guwanan, E.3    Sakakibara, S.4    Do, E.5    Osaki, E.6    Yada, K.7    Okuno, T.8    Yamanishi, K.9
  • 93
    • 0030021836 scopus 로고    scopus 로고
    • DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family
    • Osada, S., Yamamoto, H., Nishi-hara, T., and Imagawa, M. (1996). DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family. J. Biol Chem. 271, 3891-3896.
    • (1996) J. Biol Chem. , vol.271 , pp. 3891-3896
    • Osada, S.1    Yamamoto, H.2    Nishi-Hara, T.3    Imagawa, M.4
  • 94
    • 80655146214 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus Rta tetramers make high-affinity interactions with repetitive DNA elements in the Mta promoter to stimulate DNA binding of RBP-Jk/CSL
    • Palmeri, D., Carroll, K. D., Gonzalez-Lopez, O., and Lukac, D. M. (2011). Kaposis sarcoma-associated herpesvirus Rta tetramers make high-affinity interactions with repetitive DNA elements in the Mta promoter to stimulate DNA binding of RBP-Jk/CSL.J. Virol 85, 11901-11915.
    • (2011) J. Virol , vol.85 , pp. 11901-11915
    • Palmeri, D.1    Carroll, K.D.2    Gonzalez-Lopez, O.3    Lukac, D.M.4
  • 95
    • 37049020932 scopus 로고    scopus 로고
    • Promoter and cell-specific transcriptional activation by the Kaposis sarcoma-associated her-pesvirus ORF57/Mta protein
    • Palmeri, D., Spadavecchia, S., Carroll, K., and Lukac, D. M. (2007). Promoter and cell-specific transcriptional activation by the Kaposis sarcoma-associated her-pesvirus ORF57/Mta protein. J. Virol. 81, 13299-13314.
    • (2007) J. Virol. , vol.81 , pp. 13299-13314
    • Palmeri, D.1    Spadavecchia, S.2    Carroll, K.3    Lukac, D.M.4
  • 97
    • 73949088047 scopus 로고    scopus 로고
    • Wide-scale use of Notch signaling factor CSL/RBP-Jkappa in RTA-mediated activation of Kaposis sarcoma-associated herpesvirus lytic genes
    • Persson, L. M., and Wilson, A. C. (2010). Wide-scale use of Notch signaling factor CSL/RBP-Jkappa in RTA-mediated activation of Kaposis sarcoma-associated herpesvirus lytic genes. J. Virol. 84, 1334-1347.
    • (2010) J. Virol. , vol.84 , pp. 1334-1347
    • Persson, L.M.1    Wilson, A.C.2
  • 98
    • 0031950270 scopus 로고    scopus 로고
    • Limited transmission of Kaposis sarcoma-associated her-pesvirus in cultured cells
    • Renne, R., Blackbourn, D., Whitby, D., Levy, J., and Ganem, D. (1998). Limited transmission of Kaposis sarcoma-associated her-pesvirus in cultured cells. J. Virol. 72, 5182-5188.
    • (1998) J. Virol. , vol.72 , pp. 5182-5188
    • Renne, R.1    Blackbourn, D.2    Whitby, D.3    Levy, J.4    Ganem, D.5
  • 99
    • 0029876473 scopus 로고    scopus 로고
    • Lytic growth of Kaposis sarcoma-associated her-pesvirus (human herpesvirus 8) in culture
    • Renne, R., Zhong, W., Herndier, B., Mcgrath, M., Abbey, N., Kedes, D., and Ganem, D. (1996). Lytic growth of Kaposis sarcoma-associated her-pesvirus (human herpesvirus 8) in culture. Nat. Med. 2, 342-346.
    • (1996) Nat. Med. , vol.2 , pp. 342-346
    • Renne, R.1    Zhong, W.2    Herndier, B.3    Mcgrath, M.4    Abbey, N.5    Kedes, D.6    Ganem, D.7
  • 100
    • 34249064632 scopus 로고    scopus 로고
    • eds D. M. Knipe and P. M. How-ley (Philadelphia, PA: Lippincott Williams and Wilkins)
    • Rickinson, A., and Kieff, E. (2007). Epstein-barr virus, in Fields Virology, eds D. M. Knipe and P. M. How-ley (Philadelphia, PA: Lippincott Williams and Wilkins), 2656-2700.
    • (2007) Epstein-barr virus, in Fields Virology , pp. 2656-2700
    • Rickinson, A.1    Kieff, E.2
  • 102
    • 0036398416 scopus 로고    scopus 로고
    • Activation of cellular and heterologous promoters by the human herpesvirus 8 replication and transcription activator
    • Roan, F., Inoue, N., and Offermann, M. K. (2002). Activation of cellular and heterologous promoters by the human herpesvirus 8 replication and transcription activator. Virology 301, 293-304.
    • (2002) Virology , vol.301 , pp. 293-304
    • Roan, F.1    Inoue, N.2    Offermann, M.K.3
  • 104
    • 77950439778 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus ORF57 protein binds and protects a nuclear noncod-ing RNA from cellular RNA decay pathways
    • doi:10.1371/journal.ppat.1000799
    • Sahin, B. B., Patel, D., and Conrad, N. K. (2010). Kaposis sarcoma-associated herpesvirus ORF57 protein binds and protects a nuclear noncod-ing RNA from cellular RNA decay pathways. PLoS Pathog. 6, e1000799. doi:10.1371/journal.ppat.1000799
    • (2010) PLoS Pathog , vol.6
    • Sahin, B.B.1    Patel, D.2    Conrad, N.K.3
  • 105
    • 0034960341 scopus 로고    scopus 로고
    • Octamer-binding sequence is a key element for the autoregulation of Kaposis sarcoma-associated herpesvirus ORF50/Lyta gene expression.
    • Sakakibara, S., Ueda, K., Chen, J., Okuno, T., and Yamanishi, K. (2001). Octamer-binding sequence is a key element for the autoregulation of Kaposis sarcoma-associated herpesvirus ORF50/Lyta gene expression. J. Virol. 75, 6894-6800.
    • (2001) J. Virol. , vol.75 , pp. 6800-6894
    • Sakakibara, S.1    Ueda, K.2    Chen, J.3    Okuno, T.4    Yamanishi, K.5
  • 106
    • 21644438873 scopus 로고    scopus 로고
    • Cloning and identification of a microRNA cluster within the latency-associated region of Kaposis sarcoma-associated herpesvirus
    • Samols, M. A., Hu, J., Skalsky, R. L., and Renne, R. (2005). Cloning and identification of a microRNA cluster within the latency-associated region of Kaposis sarcoma-associated herpesvirus. J. Virol. 79, 9301-9305.
    • (2005) J. Virol. , vol.79 , pp. 9301-9305
    • Samols, M.A.1    Hu, J.2    Skalsky, R.L.3    Renne, R.4
  • 107
    • 0031883550 scopus 로고    scopus 로고
    • Transcription mapping of the Kaposis sarcoma-associated her-pesvirus (human herpesvirus 8) genome in a body cavity-based lym-phoma cell line (BC-1)
    • Sarid, R., Flore, O., Bohenzky, R. A., Chang, Y., and Moore, P. S. (1998). Transcription mapping of the Kaposis sarcoma-associated her-pesvirus (human herpesvirus 8) genome in a body cavity-based lym-phoma cell line (BC-1). J. Virol. 72, 1005-1012.
    • (1998) J. Virol. , vol.72 , pp. 1005-1012
    • Sarid, R.1    Flore, O.2    Bohenzky, R.A.3    Chang, Y.4    Moore, P.S.5
  • 108
    • 0033604293 scopus 로고    scopus 로고
    • Gene expression from the ORF50/K8 region of Kaposis sarcoma-associated herpesvirus
    • Seaman, W., Ye, D., Wang, R., Hale, E., Weisse, M., and Quinlivan, E. (1999). Gene expression from the ORF50/K8 region of Kaposis sarcoma-associated herpesvirus. Virology 263, 436-449.
    • (1999) Virology , vol.263 , pp. 436-449
    • Seaman, W.1    Ye, D.2    Wang, R.3    Hale, E.4    Weisse, M.5    Quinlivan, E.6
  • 109
    • 80052955255 scopus 로고    scopus 로고
    • Delineation of a core RNA element required for Kaposis sarcoma-associated herpesvirus ORF57 binding and activity
    • Sei, E., and Conrad, N. K. (2011). Delineation of a core RNA element required for Kaposis sarcoma-associated herpesvirus ORF57 binding and activity. Virology 419, 107-116.
    • (2011) Virology , vol.419 , pp. 107-116
    • Sei, E.1    Conrad, N.K.2
  • 110
    • 0035108050 scopus 로고    scopus 로고
    • Transcription activation of polyadenylated nuclear RNA by Rtainhuman herpesvirus 8/Kaposis sarcoma-associated herpesvirus
    • Song,M.,Brown,H.,Wu,T.-T.,and Sun, R. (2001). Transcription activation of polyadenylated nuclear RNA by Rtainhuman herpesvirus 8/Kaposis sarcoma-associated herpesvirus. J. Virol. 75, 3129-3140.
    • (2001) J. Virol. , vol.75 , pp. 3129-3140
    • Song, M.1    Brown, H.2    Wu, T.-T.3    Sun, R.4
  • 111
    • 0041387440 scopus 로고    scopus 로고
    • Comparative study of regulation of RTA-responsive genes in Kaposis sarcoma-associated her-pesvirus/human herpesvirus 8
    • Song, M. J., Deng, H., and Sun, R. (2003). Comparative study of regulation of RTA-responsive genes in Kaposis sarcoma-associated her-pesvirus/human herpesvirus 8. J. Virol. 77, 9451-9462.
    • (2003) J. Virol. , vol.77 , pp. 9451-9462
    • Song, M.J.1    Deng, H.2    Sun, R.3
  • 113
    • 0036241373 scopus 로고    scopus 로고
    • Characterization of interactions between RTA and the promoter of polyadenylated nuclear RNA in Kaposis sarcoma-associated herpesvirus/human herpesvirus 8
    • Song, M. J., Li, X., Brown, H. J., and Sun, R. (2002). Characterization of interactions between RTA and the promoter of polyadenylated nuclear RNA in Kaposis sarcoma-associated herpesvirus/human herpesvirus 8. J. Virol. 76, 5000-5013.
    • (2002) J. Virol. , vol.76 , pp. 5000-5013
    • Song, M.J.1    Li, X.2    Brown, H.J.3    Sun, R.4
  • 114
    • 77957194400 scopus 로고    scopus 로고
    • Convergence of Kaposis sarcoma-associated her-pesvirus reactivation with Epstein-Barr virus latency and cellular growth mediated by the notch signaling pathway in coinfected cells
    • Spadavecchia, S., Gonzalez-Lopez, O., Carroll, K. D., Palmeri, D, and Lukac, D. M. (2010). Convergence of Kaposis sarcoma-associated her-pesvirus reactivation with Epstein-Barr virus latency and cellular growth mediated by the notch signaling pathway in coinfected cells. J. Virol. 84, 10488-10500.
    • (2010) J. Virol. , vol.84 , pp. 10488-10500
    • Spadavecchia, S.1    Gonzalez-Lopez, O.2    Carroll, K.D.3    Palmeri, D.4    Lukac, D.M.5
  • 115
    • 0032899921 scopus 로고    scopus 로고
    • Cellular tropism and viral interleukin-6 expression distinguish human herpesvirus 8 involvement in Kaposis sarcoma, primary effusion lymphoma, and multicentric Castlemans disease
    • Staskus, K. A., Sun, R., Miller, G., Racz, P., Jaslowski, A., Metroka, C., Brett-Smith, H., and Haase, A. T. (1999). Cellular tropism and viral interleukin-6 expression distinguish human herpesvirus 8 involvement in Kaposis sarcoma, primary effusion lymphoma, and multicentric Castlemans disease. J. Virol. 73, 4181-4187.
    • (1999) J. Virol. , vol.73 , pp. 4181-4187
    • Staskus, K.A.1    Sun, R.2    Miller, G.3    Racz, P.4    Jaslowski, A.5    Metroka, C.6    Brett-Smith, H.7    Haase, A.T.8
  • 117
    • 0029966233 scopus 로고    scopus 로고
    • Polyadeny-lated nuclear RNA encoded by Kaposis sarcoma-associated her-pesvirus
    • Sun, R., Lin, S., Gradoville, L., and Miller, G. (1996). Polyadeny-lated nuclear RNA encoded by Kaposis sarcoma-associated her-pesvirus. Proc. Natl. Acad. Sci. U.S.A. 93, 11883-11888.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 11883-11888
    • Sun, R.1    Lin, S.2    Gradoville, L.3    Miller, G.4
  • 118
    • 0032167919 scopus 로고    scopus 로고
    • A viral gene that activates lytic cycle expression of Kaposis sarcoma-associated herpesvirus
    • Sun, R., Lin, S. F., Gradoville, L.,Yuan,Y., Zhu, F., and Miller, G. (1998). A viral gene that activates lytic cycle expression of Kaposis sarcoma-associated herpesvirus. Proc. Natl. Acad. Sci. U.S.A. 95, 10866-10871.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 10866-10871
    • Sun, R.1    Lin, S.F.2    Gradoville, L.3    Yuan, Y.4    Zhu, F.5    Miller, G.6
  • 120
    • 24744457577 scopus 로고    scopus 로고
    • Post-transcriptional gene regulation by gamma herpesviruses
    • Swaminathan, S. (2005). Post-transcriptional gene regulation by gamma herpesviruses. J. Cell. Biochem. 95, 698-711.
    • (2005) J. Cell. Biochem. , vol.95 , pp. 698-711
    • Swaminathan, S.1
  • 121
    • 77956316745 scopus 로고    scopus 로고
    • Two opposing roles of RBP-J in Notch signaling
    • Tanigaki, K., and Honjo, T. (2010). Two opposing roles of RBP-J in Notch signaling. Curr. Top. Dev. Biol. 92, 231-252.
    • (2010) Curr. Top. Dev. Biol. , vol.92 , pp. 231-252
    • Tanigaki, K.1    Honjo, T.2
  • 122
    • 79960396328 scopus 로고    scopus 로고
    • Mutation of a C-terminal motif affects Kaposis sarcoma-associated her-pesvirus ORF57 RNA binding, nuclear trafficking, and multimer-ization
    • Taylor, A., Jackson, B. R., Noeren-berg, M., Hughes, D. J., Boyne, J. R., Verow, M., Harris, M., and Whitehouse, A. (2011). Mutation of a C-terminal motif affects Kaposis sarcoma-associated her-pesvirus ORF57 RNA binding, nuclear trafficking, and multimer-ization. J. Virol. 85, 7881-7891.
    • (2011) J. Virol. , vol.85 , pp. 7881-7891
    • Taylor, A.1    Jackson, B.R.2    Noerenberg, M.3    Hughes, D.J.4    Boyne, J.R.5    Verow, M.6    Harris, M.7    Whitehouse, A.8
  • 124
    • 0036888922 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus (human herpesvirus 8) replication and transcription factor activates the K9 (vIRF) gene through two distinct cis elements by a non-DNA-binding mechanism
    • Ueda, K., Ishikawa, K., Nishimura, K., Sakakibara, S., Do, E., and Yamanishi, K. (2002). Kaposis sarcoma-associated herpesvirus (human herpesvirus 8) replication and transcription factor activates the K9 (vIRF) gene through two distinct cis elements by a non-DNA-binding mechanism. J. Virol. 76, 12044-12054.
    • (2002) J. Virol. , vol.76 , pp. 12044-12054
    • Ueda, K.1    Ishikawa, K.2    Nishimura, K.3    Sakakibara, S.4    Do, E.5    Yamanishi, K.6
  • 125
    • 3142604959 scopus 로고    scopus 로고
    • Use of the red fluorescent protein as a marker of Kaposis sarcoma-associated herpesvirus lytic gene expression
    • Vieira, J., and O'Hearn, P. M. (2004). Use of the red fluorescent protein as a marker of Kaposis sarcoma-associated herpesvirus lytic gene expression. Virology 325, 225-240.
    • (2004) Virology , vol.325 , pp. 225-240
    • Vieira, J.1    O'Hearn, P.M.2
  • 126
    • 13444310875 scopus 로고    scopus 로고
    • Modulation of human herpesvirus 8/Kaposis sarcoma-associated herpesvirus replication and transcription activator trans-activation by interferon regulatory factor 7
    • Wang, J., Zhang, J., Zhang, L., Harrington, W. Jr., West, J. T., and Wood, C. (2005). Modulation of human herpesvirus 8/Kaposis sarcoma-associated herpesvirus replication and transcription activator trans-activation by interferon regulatory factor 7. J. Virol. 79, 2420-2431.
    • (2005) J. Virol. , vol.79 , pp. 2420-2431
    • Wang, J.1    Zhang, J.2    Zhang, L.3    Harrington Jr., W.4    West, J.T.5    Wood, C.6
  • 127
    • 0034901797 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus/human herpesvirus-8 ORF50 gene prod uct contains a potent C-terminal activation domain which activates gene expression via a specific target sequence
    • Wang, S., Liu, S., Wu, M., Geng, Y., and Wood, C. (2001a). Kaposis sarcoma-associated herpesvirus/human herpesvirus-8 ORF50 gene prod uct contains a potent C-terminal activation domain which activates gene expression via a specific target sequence. Arch. Virol. 146, 1415-1426.
    • (2001) Arch. Virol. , vol.146 , pp. 1415-1426
    • Wang, S.1    Liu, S.2    Wu, M.3    Geng, Y.4    Wood, C.5
  • 128
    • 0035201957 scopus 로고    scopus 로고
    • Identification of a cellular protein that interacts and synergizes with the RTA (ORF50) protein of Kaposis sarcoma-associated herpesvirus in transcriptional activation
    • Wang, S., Liu, S., Wu, M. H., Geng, Y., and Wood, C. (2001b). Identification of a cellular protein that interacts and synergizes with the RTA (ORF50) protein of Kaposis sarcoma-associated herpesvirus in transcriptional activation. J. Virol. 75, 11961-11973.
    • (2001) J. Virol. , vol.75 , pp. 11961-11973
    • Wang, S.1    Liu, S.2    Wu, M.H.3    Geng, Y.4    Wood, C.5
  • 129
    • 1842431602 scopus 로고    scopus 로고
    • Early activation of the Kaposis sarcoma-associated herpesvirus RTA, RAP, and MTA promoters by the tetradecanoyl phorbol acetate-induced AP1 pathway
    • Wang, S. E., Wu, F. Y., Chen, H., Shamay, M., Zheng, Q., and Hayward, G. S. (2004a). Early activation of the Kaposis sarcoma-associated herpesvirus RTA, RAP, and MTA promoters by the tetradecanoyl phorbol acetate-induced AP1 pathway. J. Virol. 78, 4248-4267.
    • (2004) J. Virol. , vol.78 , pp. 4248-4267
    • Wang, S.E.1    Wu, F.Y.2    Chen, H.3    Shamay, M.4    Zheng, Q.5    Hayward, G.S.6
  • 130
    • 3543068693 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated her-pesvirus ori-Lyt-dependent DNA replication: cis-acting requirements for replication and ori-Lyt-associated RNA transcription
    • Wang, Y., Li, H., Chan, M. Y., Zhu, F. X., Lukac, D. M., and Yuan, Y. (2004b). Kaposis sarcoma-associated her-pesvirus ori-Lyt-dependent DNA replication: cis-acting requirements for replication and ori-Lyt-associated RNA transcription. J. Virol. 78, 8615-8629.
    • (2004) J. Virol. , vol.78 , pp. 8615-8629
    • Wang, Y.1    Li, H.2    Chan, M.Y.3    Zhu, F.X.4    Lukac, D.M.5    Yuan, Y.6
  • 131
    • 0037213589 scopus 로고    scopus 로고
    • Role of CCAAT/enhancer-binding protein alpha (C/EBPalpha) in activation of the Kaposis sarcoma-associated herpesvirus (KSHV) lytic-cycle replication-associated protein (RAP) promoter in cooperation with the KSHV replication and transcription activator (RTA) and RAP
    • Wang, S. E., Wu, F. Y., Fujimuro, M., Zong, J., Hayward, S. D., and Hayward, G. S. (2003a). Role of CCAAT/enhancer-binding protein alpha (C/EBPalpha) in activation of the Kaposis sarcoma-associated herpesvirus (KSHV) lytic-cycle replication-associated protein (RAP) promoter in cooperation with the KSHV replication and transcription activator (RTA) and RAP. J. Virol. 77, 600-623.
    • (2003) J. Virol. , vol.77 , pp. 600-623
    • Wang, S.E.1    Wu, F.Y.2    Fujimuro, M.3    Zong, J.4    Hayward, S.D.5    Hayward, G.S.6
  • 132
    • 0042890345 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein-alpha is induced during the early stages of Kaposis sarcoma-associated herpesvirus (KSHV) lytic cycle reactivation and together with the KSHV replication and transcription activator (RTA) cooperatively stimulates the viral RTA, MTA, and PAN promoters
    • Wang, S. E., Wu, F. Y., Yu, Y., and Hayward, G. S. (2003b). CCAAT/enhancer-binding protein-alpha is induced during the early stages of Kaposis sarcoma-associated herpesvirus (KSHV) lytic cycle reactivation and together with the KSHV replication and transcription activator (RTA) cooperatively stimulates the viral RTA, MTA, and PAN promoters. J. Virol. 77, 9590-9612.
    • (2003) J. Virol. , vol.77 , pp. 9590-9612
    • Wang, S.E.1    Wu, F.Y.2    Yu, Y.3    Hayward, G.S.4
  • 133
    • 75749114015 scopus 로고    scopus 로고
    • Transcrip-tional regulation of the ORF61 and ORF60 genes of Kaposis sarcoma-associated herpesvirus
    • Wang, S. S., Chen, L. W., Chen, L. Y., Tsai, H. H., Shih, Y. C., Yang, C. T., and Chang, P. J. (2010). Transcrip-tional regulation of the ORF61 and ORF60 genes of Kaposis sarcoma-associated herpesvirus. Virology 397, 311-321.
    • (2010) Virology , vol.397 , pp. 311-321
    • Wang, S.S.1    Chen, L.W.2    Chen, L.Y.3    Tsai, H.H.4    Shih, Y.C.5    Yang, C.T.6    Chang, P.J.7
  • 134
    • 33845427459 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus ori-Lyt-dependent DNA replication: dual role of replication and transcription activator
    • Wang, Y., Tang, Q., Maul, G. G., and Yuan, Y. (2006). Kaposis sarcoma-associated herpesvirus ori-Lyt-dependent DNA replication: dual role of replication and transcription activator. J. Virol. 80, 12171-12186.
    • (2006) J. Virol. , vol.80 , pp. 12171-12186
    • Wang, Y.1    Tang, Q.2    Maul, G.G.3    Yuan, Y.4
  • 135
    • 33846826978 scopus 로고    scopus 로고
    • Essential role of RBP-Jkappa in activation of the K8 delayed-early promoter of Kaposis sarcoma-associated her-pesvirus by ORF50/RTA
    • Wang, Y., and Yuan, Y. (2006). Essential role of RBP-Jkappa in activation of the K8 delayed-early promoter of Kaposis sarcoma-associated her-pesvirus by ORF50/RTA. Virology 359, 19-27.
    • (2006) Virology , vol.359 , pp. 19-27
    • Wang, Y.1    Yuan, Y.2
  • 136
    • 65549142132 scopus 로고    scopus 로고
    • Identification and characterization of a new Kaposis sarcoma-associated herpesvirus replication and transcription activator (RTA)-responsive element involved in RTA-mediated transactivation
    • Wen, H. J., Minhas, V., and Wood, C. (2009). Identification and characterization of a new Kaposis sarcoma-associated herpesvirus replication and transcription activator (RTA)-responsive element involved in RTA-mediated transactivation. J. Gen. Virol. 90, 944-953.
    • (2009) J. Gen. Virol. , vol.90 , pp. 944-953
    • Wen, H.J.1    Minhas, V.2    Wood, C.3
  • 137
    • 37049016021 scopus 로고    scopus 로고
    • X box binding protein XBP-1s transactivates the Kaposis sarcoma-associated her-pesvirus (KSHV) ORF50 promoter, linking plasma cell differentiation to KSHV reactivation from latency
    • Wilson, S. J., Tsao, E. H., Webb, B. L., Ye, H., Dalton-Griffin, L., Tsantoulas, C., Gale, C. V., Du, M. Q., Whitehouse, A., and Kel-lam, P. (2007). X box binding protein XBP-1s transactivates the Kaposis sarcoma-associated her-pesvirus (KSHV) ORF50 promoter, linking plasma cell differentiation to KSHV reactivation from latency. J. Virol. 81, 13578-13586.
    • (2007) J. Virol. , vol.81 , pp. 13578-13586
    • Wilson, S.J.1    Tsao, E.H.2    Webb, B.L.3    Ye, H.4    Dalton-Griffin, L.5    Tsantoulas, C.6    Gale, C.V.7    Du, M.Q.8    Whitehouse, A.9    Kel-lam, P.10
  • 138
    • 34249817126 scopus 로고    scopus 로고
    • Epstein-barr virus inhibits Kaposis sarcoma-associated her-pesvirus lytic replication in primary effusion lymphomas
    • Xu, D., Coleman, T., Zhang, J., Fagot, A., Kotalik, C., Zhao, L., Trivedi, P., Jones, C., and Zhang, L. (2007). Epstein-barr virus inhibits Kaposis sarcoma-associated her-pesvirus lytic replication in primary effusion lymphomas. J. Virol. 81, 6068-6078.
    • (2007) J. Virol. , vol.81 , pp. 6068-6078
    • Xu, D.1    Coleman, T.2    Zhang, J.3    Fagot, A.4    Kotalik, C.5    Zhao, L.6    Trivedi, P.7    Jones, C.8    Zhang, L.9
  • 139
    • 14744270253 scopus 로고    scopus 로고
    • A Kaposis sarcoma-associated herpesvirus/human her-pesvirus 8 ORF50 deletion mutant is defective for reactivation of latent virus and DNA replication
    • Xu, Y., Aucoin, D. P., Huete, A. R., Cei, S. A., Hanson, L. J., and Pari, G. S. (2005). A Kaposis sarcoma-associated herpesvirus/human her-pesvirus 8 ORF50 deletion mutant is defective for reactivation of latent virus and DNA replication. J. Virol. 79, 3479-3487.
    • (2005) J. Virol. , vol.79 , pp. 3479-3487
    • Xu, Y.1    Aucoin, D.P.2    Huete, A.R.3    Cei, S.A.4    Hanson, L.J.5    Pari, G.S.6
  • 140
    • 77952003905 scopus 로고    scopus 로고
    • Making sense of antisense: seemingly noncoding RNAs antisense to the master regulator of Kaposis sarcoma-associated herpesvirus lytic replication do not regulate that transcript but serve as mRNAs encoding small peptides
    • Xu, Y., and Ganem, D. (2010). Making sense of antisense: seemingly noncoding RNAs antisense to the master regulator of Kaposis sarcoma-associated herpesvirus lytic replication do not regulate that transcript but serve as mRNAs encoding small peptides. J. Virol. 84, 5465-5475.
    • (2010) J. Virol. , vol.84 , pp. 5465-5475
    • Xu, Y.1    Ganem, D.2
  • 142
    • 68549088708 scopus 로고    scopus 로고
    • The zinc finger DNA-binding domain of K-RBP plays an important role in regulating Kaposis sarcoma-associated her-pesvirus RTA-mediated gene expression
    • Yang, Z., Wen, H. J., Minhas, V., and Wood, C. (2009). The zinc finger DNA-binding domain of K-RBP plays an important role in regulating Kaposis sarcoma-associated her-pesvirus RTA-mediated gene expression. Virology 391, 221-231.
    • (2009) Virology , vol.391 , pp. 221-231
    • Yang, Z.1    Wen, H.J.2    Minhas, V.3    Wood, C.4
  • 143
    • 34249931319 scopus 로고    scopus 로고
    • The tran-scriptional repressor K-RBP modulates RTA-mediated transactivation and lytic replication of Kaposis sarcoma-associated herpesvirus
    • Yang,Z., and Wood, C. (2007). The tran-scriptional repressor K-RBP modulates RTA-mediated transactivation and lytic replication of Kaposis sarcoma-associated herpesvirus. J. Virol. 81, 6294-6306.
    • (2007) J. Virol. , vol.81 , pp. 6294-6306
    • Yang, Z.1    Wood, C.2
  • 144
    • 41149167561 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus transactivator RTA promotes degradation of the repressors to regulate viral lytic replication
    • Yang, Z., Yan, Z., and Wood, C. (2008). Kaposis sarcoma-associated herpesvirus transactivator RTA promotes degradation of the repressors to regulate viral lytic replication. J. Virol. 82, 3590-3603.
    • (2008) J. Virol. , vol.82 , pp. 3590-3603
    • Yang, Z.1    Yan, Z.2    Wood, C.3
  • 145
    • 12444275739 scopus 로고    scopus 로고
    • The KSHV immediate-early transcription factor RTA encodes ubiquitin E3 ligase activity that targets IRF7 for proteosome-mediated degradation
    • Yu, Y., Wang, S. E., and Hayward, G. S. (2005). The KSHV immediate-early transcription factor RTA encodes ubiquitin E3 ligase activity that targets IRF7 for proteosome-mediated degradation. Immunity 22, 59-70.
    • (2005) Immunity , vol.22 , pp. 59-70
    • Yu, Y.1    Wang, S.E.2    Hayward, G.S.3
  • 146
    • 17444429652 scopus 로고    scopus 로고
    • Kaposis sarcoma-associated herpesvirus/human her-pesvirus 8 replication and transcription activator regulates viral and cellular genes via interferon-stimulated response elements
    • Zhang, J.,Wang, J., Wood, C., Xu, D., and Zhang, L. (2005). Kaposis sarcoma-associated herpesvirus/human her-pesvirus 8 replication and transcription activator regulates viral and cellular genes via interferon-stimulated response elements. J. Virol. 79, 5640-5652.
    • (2005) J. Virol. , vol.79 , pp. 5640-5652
    • Zhang, J.1    Wang, J.2    Wood, C.3    Xu, D.4    Zhang, L.5
  • 147
    • 0031663415 scopus 로고    scopus 로고
    • Activation of human herpesvirus 8 (HHV-8) thymidine kinase (TK) TATAA-less promoter by HHV-8 ORF50 gene product is SP1 dependent
    • Zhang, L., Chiu, J., and Lin, J. C. (1998). Activation of human herpesvirus 8 (HHV-8) thymidine kinase (TK) TATAA-less promoter by HHV-8 ORF50 gene product is SP1 dependent. DNA Cell Biol. 17, 735-742.
    • (1998) DNA Cell Biol , vol.17 , pp. 735-742
    • Zhang, L.1    Chiu, J.2    Lin, J.C.3
  • 148
    • 0029957833 scopus 로고    scopus 로고
    • Restricted expression of Kaposi sarcoma-associated herpesvirus (human her-pesvirus 8) genes in Kaposi sarcoma
    • Zhong, W., Wang, H., Herndier, B., and Ganem, D. (1996). Restricted expression of Kaposi sarcoma-associated herpesvirus (human her-pesvirus 8) genes in Kaposi sarcoma. Proc. Natl. Acad. Sci. U.S.A. 93, 6641-6646.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 6641-6646
    • Zhong, W.1    Wang, H.2    Herndier, B.3    Ganem, D.4
  • 149
    • 0001293583 scopus 로고    scopus 로고
    • Identification of the immediate-early transcripts of Kaposis sarcoma-associated herpesvirus
    • Zhu, F., Cusano, T., and Yuan,Y. (1999). Identification of the immediate-early transcripts of Kaposis sarcoma-associated herpesvirus. J. Virol. 73, 5556-5567.
    • (1999) J. Virol. , vol.73 , pp. 5556-5567
    • Zhu, F.1    Cusano, T.2    Yuan, Y.3
  • 150
    • 33644778764 scopus 로고    scopus 로고
    • Exploring the DNA binding interactions of the Kaposis sarcoma-associated her-pesvirus lytic switch protein by selective amplification of bound sequences in vitro
    • Ziegelbauer, J., Grundhoff, A., and Ganem, D. (2006). Exploring the DNA binding interactions of the Kaposis sarcoma-associated her-pesvirus lytic switch protein by selective amplification of bound sequences in vitro. J. Virol. 80, 2958-2967.
    • (2006) J. Virol , vol.80 , pp. 2958-2967
    • Ziegelbauer, J.1    Grundhoff, A.2    Ganem, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.