Dynamic allostery governs cyclophilin A-HIV capsid interplay

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 47, 2015, Pages 14617-14622

  Lu, Manman ^a,b   Hou, Guangjin ^a,b   Zhang, Huilan ^a,b   Suiter, Christopher L ^a,b   Ahn, Jinwoo ^b   Byeon, In Ja L ^b   Perilla, Juan R ^c   Langmead, Christopher J ^d   Hung, Ivan ^e   Gor'kov, Peter L ^e   Gan, Zhehong ^e   Brey, William ^e   Aiken, Christopher ^b,f   Zhang, Peijun ^b   Schulten, Klaus ^c   Gronenborn, Angela M ^b   Polenova, Tatyana ^a,b  

^a UNIVERSITY OF DELAWARE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d Carnegie Mellon University ^*  (United States)

^e FLORIDA STATE UNIVERSITY   (United States)

^f VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Ca protein assemblies; Conformational dynamics; Escape mutations; HIV 1 capsid; Magic angle spinning nmr

Indexed keywords

CYCLOPHILIN A; MUTANT PROTEIN;

ALLOSTERISM; CARBON NUCLEAR MAGNETIC RESONANCE; CONFERENCE PAPER; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR DYNAMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; VIRUS CAPSID; VIRUS MUTANT; WILD TYPE; CHEMISTRY; GENETICS; HUMAN; MUTATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TIME FACTOR; ULTRASTRUCTURE;

ALLOSTERIC REGULATION; CAPSID; CYCLOPHILIN A; HIV-1; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR DYNAMICS SIMULATION; MUTANT PROTEINS; MUTATION; TIME FACTORS;

EID: 84948399772     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1516920112     Document Type: Article

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