-
1
-
-
84893211760
-
Next-generation sequencing reveals how RNA catalysts evolve from random space
-
COI: 1:CAS:528:DC%2BC2cXhtlShtrs%3D, PID: 24157838
-
Ameta S, Winz M-L, Previti C, Jäschke A (2014) Next-generation sequencing reveals how RNA catalysts evolve from random space. Nucleic Acids Res 42:1303–1310
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 1303-1310
-
-
Ameta, S.1
Winz, M.-L.2
Previti, C.3
Jäschke, A.4
-
2
-
-
0028675028
-
A DNA enzyme that cleaves RNA
-
COI: 1:CAS:528:DyaK2MXksVOht7c%3D, PID: 9383394
-
Breaker RR, Joyce GF (1994) A DNA enzyme that cleaves RNA. Chem Biol 1:223–229
-
(1994)
Chem Biol
, vol.1
, pp. 223-229
-
-
Breaker, R.R.1
Joyce, G.F.2
-
3
-
-
0022433369
-
Crystallographic and biochemical investigation of the lead(II)-catalyzed hydrolysis of yeast phenylalanine tRNA
-
COI: 1:CAS:528:DyaL2MXkvF2rsb4%3D, PID: 3907691
-
Brown RS, Dewan JC, Klug A (1985) Crystallographic and biochemical investigation of the lead(II)-catalyzed hydrolysis of yeast phenylalanine tRNA. Biochemistry 24:4785–4801
-
(1985)
Biochemistry
, vol.24
, pp. 4785-4801
-
-
Brown, R.S.1
Dewan, J.C.2
Klug, A.3
-
4
-
-
0038131065
-
A lead-dependent DNAzyme with a two-step mechanism
-
COI: 1:CAS:528:DC%2BD3sXjvFCntL4%3D, PID: 12795611
-
Brown AK, Li J, Pavot CMB, Lu Y (2003) A lead-dependent DNAzyme with a two-step mechanism. Biochemistry 42:7152–7161
-
(2003)
Biochemistry
, vol.42
, pp. 7152-7161
-
-
Brown, A.K.1
Li, J.2
Pavot, C.M.B.3
Lu, Y.4
-
5
-
-
60349125967
-
Biochemical characterization of a uranyl ion-specific DNAzyme
-
COI: 1:CAS:528:DC%2BD1MXis1amsL0%3D, PID: 19142882
-
Brown AK, Liu JW, He Y, Lu Y (2009) Biochemical characterization of a uranyl ion-specific DNAzyme. ChemBioChem 10:486–492
-
(2009)
ChemBioChem
, vol.10
, pp. 486-492
-
-
Brown, A.K.1
Liu, J.W.2
He, Y.3
Lu, Y.4
-
6
-
-
0030934345
-
Effect of structural modifications on the activity of the leadzyme
-
COI: 1:CAS:528:DyaK2sXhtlGju70%3D, PID: 9115990
-
Chartrand P, Usman N, Cedergren R (1997) Effect of structural modifications on the activity of the leadzyme. Biochemistry 36:3145–3150
-
(1997)
Biochemistry
, vol.36
, pp. 3145-3150
-
-
Chartrand, P.1
Usman, N.2
Cedergren, R.3
-
7
-
-
1142281951
-
Dinucleotide junction cleavage versatility of 8–17 deoxyribozyme
-
COI: 1:CAS:528:DC%2BD2cXps1ynuw%3D%3D, PID: 15112995
-
Cruz RPG, Withers JB, Li Y (2004) Dinucleotide junction cleavage versatility of 8–17 deoxyribozyme. Chem Biol 11:57–67
-
(2004)
Chem Biol
, vol.11
, pp. 57-67
-
-
Cruz, R.P.G.1
Withers, J.B.2
Li, Y.3
-
8
-
-
84982062745
-
Uber die hydrolyse von ribonucleinsauren in gegenwart von metallhydroxyden
-
COI: 1:CAS:528:DyaF3MXlsVKksA%3D%3D
-
Dimroth K, Witzel H, Hulsen W, Mirbach H (1959) Uber die hydrolyse von ribonucleinsauren in gegenwart von metallhydroxyden. Annalen Der Chemie-Justus Liebig 620:94–108
-
(1959)
Annalen Der Chemie-Justus Liebig
, vol.620
, pp. 94-108
-
-
Dimroth, K.1
Witzel, H.2
Hulsen, W.3
Mirbach, H.4
-
9
-
-
0014430593
-
Depolymerization of ribonucleic acid by plumbous ion. Biochimica et biophysica acta (BBA)—nucleic acids and protein
-
COI: 1:CAS:528:DyaF1cXnsFWltg%3D%3D
-
Farkas WR (1968) Depolymerization of ribonucleic acid by plumbous ion. Biochimica et biophysica acta (BBA)—nucleic acids and protein. Synthesis 155:401–409
-
(1968)
Synthesis
, vol.155
, pp. 401-409
-
-
Farkas, W.R.1
-
10
-
-
0032573424
-
NMR solution structure of the lead-dependent ribozyme: evidence for dynamics in RNA catalysis
-
COI: 1:CAS:528:DyaK1cXnvVequrs%3D, PID: 9813122
-
Hoogstraten CG, Legault P, Pardi A (1998) NMR solution structure of the lead-dependent ribozyme: evidence for dynamics in RNA catalysis. J Mol Biol 284:337–350
-
(1998)
J Mol Biol
, vol.284
, pp. 337-350
-
-
Hoogstraten, C.G.1
Legault, P.2
Pardi, A.3
-
11
-
-
0034664076
-
Active site dynamics in the lead-dependent ribozyme
-
COI: 1:CAS:528:DC%2BD3cXkvFeqsrs%3D, PID: 10933815
-
Hoogstraten CG, Wank JR, Pardi A (2000) Active site dynamics in the lead-dependent ribozyme. Biochemistry 39:9951–9958
-
(2000)
Biochemistry
, vol.39
, pp. 9951-9958
-
-
Hoogstraten, C.G.1
Wank, J.R.2
Pardi, A.3
-
12
-
-
84897523395
-
2+-specific dnazymes with opposite trends in split-site-dependent activity
-
COI: 1:CAS:528:DC%2BC2cXlt1artbs%3D
-
2+-specific dnazymes with opposite trends in split-site-dependent activity. Chem Commun 50:4442–4444
-
(2014)
Chem Commun
, vol.50
, pp. 4442-4444
-
-
Huang, P.-J.J.1
Liu, J.2
-
13
-
-
84893540958
-
Ultrasensitive DNAzyme beacon for lanthanides and metal speciation
-
COI: 1:CAS:528:DC%2BC2cXhsl2ksw%3D%3D, PID: 24383540
-
Huang P-JJ, Lin J, Cao J, Vazin M, Liu J (2014a) Ultrasensitive DNAzyme beacon for lanthanides and metal speciation. Anal Chem 86:1816–1821
-
(2014)
Anal Chem
, vol.86
, pp. 1816-1821
-
-
Huang, P.-J.J.1
Lin, J.2
Cao, J.3
Vazin, M.4
Liu, J.5
-
14
-
-
84907894839
-
In vitro selection of a new lanthanide-dependent DNAzyme for ratiometric sensing lanthanides
-
COI: 1:CAS:528:DC%2BC2cXhsFWjsbrN, PID: 25199650
-
Huang P-JJ, Vazin M, Liu J (2014b) In vitro selection of a new lanthanide-dependent DNAzyme for ratiometric sensing lanthanides. Anal Chem 86:9993–9999
-
(2014)
Anal Chem
, vol.86
, pp. 9993-9999
-
-
Huang, P.-J.J.1
Vazin, M.2
Liu, J.3
-
15
-
-
66149139414
-
Conformational distribution and ultrafast base dynamics of leadzyme
-
COI: 1:CAS:528:DC%2BD1MXjvVSqt7Y%3D, PID: 19301929
-
Kadakkuzha BM, Zhao L, Xia T (2009) Conformational distribution and ultrafast base dynamics of leadzyme. Biochemistry 48:3807–3809
-
(2009)
Biochemistry
, vol.48
, pp. 3807-3809
-
-
Kadakkuzha, B.M.1
Zhao, L.2
Xia, T.3
-
16
-
-
36248936102
-
Dissecting metal ion-dependent folding and catalysis of a single DNAzyme
-
Kim HK, Rasnik I, Liu JW, Ha TJ, Lu Y (2007) Dissecting metal ion-dependent folding and catalysis of a single DNAzyme. Nat Chem Biol 3:762–768
-
(2007)
Nat Chem Biol
, vol.3
, pp. 762-768
-
-
Kim, H.K.1
Rasnik, I.2
Liu, J.W.3
Ha, T.J.4
Lu, Y.5
-
17
-
-
77952784379
-
A highly selective lead sensor based on a classic lead DNAzyme
-
COI: 1:CAS:528:DC%2BC3cXmsFSksbs%3D
-
Lan T, Furuya K, Lu Y (2010) A highly selective lead sensor based on a classic lead DNAzyme. Chem Commun 46:3896–3898
-
(2010)
Chem Commun
, vol.46
, pp. 3896-3898
-
-
Lan, T.1
Furuya, K.2
Lu, Y.3
-
18
-
-
0032573527
-
Order, dynamics and metal-binding in the lead-dependent ribozyme
-
COI: 1:CAS:528:DyaK1cXnvVequro%3D, PID: 9813121
-
Legault P, Hoogstraten CG, Metlitzky E, Pardi A (1998) Order, dynamics and metal-binding in the lead-dependent ribozyme. J Mol Biol 284:325–335
-
(1998)
J Mol Biol
, vol.284
, pp. 325-335
-
-
Legault, P.1
Hoogstraten, C.G.2
Metlitzky, E.3
Pardi, A.4
-
19
-
-
0033575087
-
Kinetics of RNA degradation by specific base catalysis of transesterification involving the 2′-hydroxyl group
-
COI: 1:CAS:528:DyaK1MXjt1aqtLk%3D
-
Li Y, Breaker RR (1999) Kinetics of RNA degradation by specific base catalysis of transesterification involving the 2′-hydroxyl group. J Am Chem Soc 121:5364–5372
-
(1999)
J Am Chem Soc
, vol.121
, pp. 5364-5372
-
-
Li, Y.1
Breaker, R.R.2
-
20
-
-
0034715471
-
A highly sensitive and selective catalytic DNA biosensor for lead ions
-
COI: 1:CAS:528:DC%2BD3cXmvFGhsr8%3D
-
Li J, Lu Y (2000) A highly sensitive and selective catalytic DNA biosensor for lead ions. J Am Chem Soc 122:10466–10467
-
(2000)
J Am Chem Soc
, vol.122
, pp. 10466-10467
-
-
Li, J.1
Lu, Y.2
-
21
-
-
0034650291
-
In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme
-
COI: 1:CAS:528:DC%2BD3cXhtVSkt7c%3D, PID: 10606646
-
Li J, Zheng W, Kwon AH, Lu Y (2000) In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme. Nucleic Acids Res 28:481–488
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 481-488
-
-
Li, J.1
Zheng, W.2
Kwon, A.H.3
Lu, Y.4
-
22
-
-
33847779647
-
A catalytic beacon sensor for uranium with parts-per-trillion sensitivity and millionfold selectivity
-
COI: 1:CAS:528:DC%2BD2sXisVWrsrs%3D, PID: 17284609
-
Liu J, Brown AK, Meng X, Cropek DM, Istok JD, Watson DB, Lu Y (2007) A catalytic beacon sensor for uranium with parts-per-trillion sensitivity and millionfold selectivity. Proc Natl Acad Sci USA 104:2056–2061
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 2056-2061
-
-
Liu, J.1
Brown, A.K.2
Meng, X.3
Cropek, D.M.4
Istok, J.D.5
Watson, D.B.6
Lu, Y.7
-
23
-
-
66249097058
-
Functional nucleic acid sensors
-
COI: 1:CAS:528:DC%2BD1MXjsFemurw%3D, PID: 19301873
-
Liu J, Cao Z, Lu Y (2009) Functional nucleic acid sensors. Chem Rev 109:1948–1998
-
(2009)
Chem Rev
, vol.109
, pp. 1948-1998
-
-
Liu, J.1
Cao, Z.2
Lu, Y.3
-
24
-
-
0037131433
-
New transition metal-dependent DNAzymes as efficient endonucleases and as selective metal biosensors
-
COI: 1:CAS:528:DC%2BD38XosVShurs%3D, PID: 12362396
-
Lu Y (2002) New transition metal-dependent DNAzymes as efficient endonucleases and as selective metal biosensors. Chem Eur J 8:4588–4596
-
(2002)
Chem Eur J
, vol.8
, pp. 4588-4596
-
-
Lu, Y.1
-
25
-
-
77957314671
-
Nucleotides that are essential but not conserved; a sufficient l-tryptophan site in RNA
-
COI: 1:CAS:528:DC%2BC3cXht1KjtbjP, PID: 20699302
-
Majerfeld I, Chocholousova J, Malaiya V, Widmann J, McDonald D, Reeder J, Iyer M, Illangasekare M, Yarus M, Knight R (2010) Nucleotides that are essential but not conserved; a sufficient l-tryptophan site in RNA. RNA 16:1915–1924
-
(2010)
RNA
, vol.16
, pp. 1915-1924
-
-
Majerfeld, I.1
Chocholousova, J.2
Malaiya, V.3
Widmann, J.4
McDonald, D.5
Reeder, J.6
Iyer, M.7
Illangasekare, M.8
Yarus, M.9
Knight, R.10
-
26
-
-
84929324645
-
Optimal DNA templates for rolling circle amplification revealed by in vitro selection
-
COI: 1:CAS:528:DC%2BC2MXmslars74%3D, PID: 25877998
-
Mao Y, Liu M, Tram K, Gu J, Salena BJ, Jiang Y, Li Y (2015) Optimal DNA templates for rolling circle amplification revealed by in vitro selection. Chem Eur J 21:8069–8074
-
(2015)
Chem Eur J
, vol.21
, pp. 8069-8074
-
-
Mao, Y.1
Liu, M.2
Tram, K.3
Gu, J.4
Salena, B.J.5
Jiang, Y.6
Li, Y.7
-
27
-
-
0032952507
-
Crystal structure of an 82-nucleotide RNA–DNA complex formed by the 10-23 DNA enzyme
-
COI: 1:CAS:528:DyaK1MXht1Cksr0%3D, PID: 10048927
-
Nowakowski J, Shim PJ, Prasad GS, Stout CD, Joyce GF (1999) Crystal structure of an 82-nucleotide RNA–DNA complex formed by the 10-23 DNA enzyme. Nat Struct Biol 6:151–156
-
(1999)
Nat Struct Biol
, vol.6
, pp. 151-156
-
-
Nowakowski, J.1
Shim, P.J.2
Prasad, G.S.3
Stout, C.D.4
Joyce, G.F.5
-
28
-
-
0032534641
-
Effect of substrate RNA sequence on the cleavage reaction by a short ribozyme
-
COI: 1:CAS:528:DyaK1MXis1Gjsg%3D%3D, PID: 9837996
-
Ohmichi T, Okumoto Y, Sugimoto N (1998) Effect of substrate RNA sequence on the cleavage reaction by a short ribozyme. Nucleic Acids Res 26:5655–5661
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 5655-5661
-
-
Ohmichi, T.1
Okumoto, Y.2
Sugimoto, N.3
-
29
-
-
0026755205
-
In vitro selection of rnas that undergo autolytic cleavage with Pb(II)
-
COI: 1:CAS:528:DyaK38XitlWhtrc%3D, PID: 1373649
-
Pan T, Uhlenbeck OC (1992a) In vitro selection of rnas that undergo autolytic cleavage with Pb(II). Biochemistry 31:3887–3895
-
(1992)
Biochemistry
, vol.31
, pp. 3887-3895
-
-
Pan, T.1
Uhlenbeck, O.C.2
-
30
-
-
0026669321
-
A small metalloribozyme with a two-step mechanism
-
COI: 1:CAS:528:DyaK3sXltlCiu7s%3D, PID: 1501711
-
Pan T, Uhlenbeck OC (1992b) A small metalloribozyme with a two-step mechanism. Nature 358:560–563
-
(1992)
Nature
, vol.358
, pp. 560-563
-
-
Pan, T.1
Uhlenbeck, O.C.2
-
32
-
-
24644514250
-
A mutational analysis of the 8-17 deoxyribozyme core
-
COI: 1:CAS:528:DC%2BD2MXhtVWit7jJ, PID: 16125199
-
Peracchi A, Bonaccio M, Clerici M (2005) A mutational analysis of the 8-17 deoxyribozyme core. J Mol Biol 352:783–794
-
(2005)
J Mol Biol
, vol.352
, pp. 783-794
-
-
Peracchi, A.1
Bonaccio, M.2
Clerici, M.3
-
33
-
-
77957963240
-
Rapid construction of empirical RNA fitness landscapes
-
COI: 1:CAS:528:DC%2BC3cXht1OisL7K, PID: 20947767
-
Pitt JN, Ferré-D’Amaré AR (2010) Rapid construction of empirical RNA fitness landscapes. Science 330:376–379
-
(2010)
Science
, vol.330
, pp. 376-379
-
-
Pitt, J.N.1
Ferré-D’Amaré, A.R.2
-
34
-
-
0030898510
-
A general purpose RNA-cleaving DNA enzyme
-
COI: 1:CAS:528:DyaK2sXjtVyit7w%3D, PID: 9113977
-
Santoro SW, Joyce GF (1997) A general purpose RNA-cleaving DNA enzyme. Proc Natl Acad Sci USA 94:4262–4266
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4262-4266
-
-
Santoro, S.W.1
Joyce, G.F.2
-
35
-
-
62649161589
-
Biologically inspired synthetic enzymes made from DNA
-
COI: 1:CAS:528:DC%2BD1MXjsVOis7c%3D, PID: 19318212
-
Schlosser K, Li YF (2009) Biologically inspired synthetic enzymes made from DNA. Chem Biol 16:311–322
-
(2009)
Chem Biol
, vol.16
, pp. 311-322
-
-
Schlosser, K.1
Li, Y.F.2
-
36
-
-
77951713609
-
A versatile endoribonuclease mimic made of DNA: characteristics and applications of the 8-17 RNA-cleaving DNAzyme
-
COI: 1:CAS:528:DC%2BC3cXlsVOqt7c%3D, PID: 20213779
-
Schlosser K, Li Y (2010) A versatile endoribonuclease mimic made of DNA: characteristics and applications of the 8-17 RNA-cleaving DNAzyme. ChemBioChem 11:866–879
-
(2010)
ChemBioChem
, vol.11
, pp. 866-879
-
-
Schlosser, K.1
Li, Y.2
-
37
-
-
49249091384
-
In vitro selection of small RNA-cleaving deoxyribozymes that cleave pyrimidine-pyrimidine junctions
-
COI: 1:CAS:528:DC%2BD1cXpslWnurY%3D, PID: 18644842
-
Schlosser K, Gu J, Lam JCF, Li YF (2008a) In vitro selection of small RNA-cleaving deoxyribozymes that cleave pyrimidine-pyrimidine junctions. Nucleic Acids Res 36:4768–4777
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 4768-4777
-
-
Schlosser, K.1
Gu, J.2
Lam, J.C.F.3
Li, Y.F.4
-
38
-
-
41149095145
-
Sequence-function relationships provide new insight into the cleavage site selectivity of the 8-17 RNA-cleaving deoxyribozyme
-
COI: 1:CAS:528:DC%2BD1cXjsValtrk%3D, PID: 18203744
-
Schlosser K, Gu J, Sule L, Li YF (2008b) Sequence-function relationships provide new insight into the cleavage site selectivity of the 8-17 RNA-cleaving deoxyribozyme. Nucleic Acids Res 36:1472–1481
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 1472-1481
-
-
Schlosser, K.1
Gu, J.2
Sule, L.3
Li, Y.F.4
-
39
-
-
33846887629
-
Alternative roles for metal ions in enzyme catalysis and the implications for ribozyme chemistry
-
COI: 1:CAS:528:DC%2BD28Xhtlantr3O, PID: 17212472
-
Sigel RKO, Pyle AM (2007) Alternative roles for metal ions in enzyme catalysis and the implications for ribozyme chemistry. Chem Rev 107:97
-
(2007)
Chem Rev
, vol.107
, pp. 97
-
-
Sigel, R.K.O.1
Pyle, A.M.2
-
40
-
-
77956133904
-
Probing the function of nucleotides in the catalytic cores of the 8-17 and 10-23 dnazymes by abasic nucleotide and C3 spacer substitutions
-
COI: 1:CAS:528:DC%2BC3cXpvVylsb0%3D, PID: 20698496
-
Wang B, Cao L, Chiuman W, Li Y, Xi Z (2010) Probing the function of nucleotides in the catalytic cores of the 8-17 and 10-23 dnazymes by abasic nucleotide and C3 spacer substitutions. Biochemistry 49:7553–7562
-
(2010)
Biochemistry
, vol.49
, pp. 7553-7562
-
-
Wang, B.1
Cao, L.2
Chiuman, W.3
Li, Y.4
Xi, Z.5
-
41
-
-
84899550322
-
Nucleic acid catalysis: metals, nucleobases, and other cofactors
-
COI: 1:CAS:528:DC%2BC2cXmt1Shu78%3D, PID: 24730975
-
Ward WL, Plakos K, DeRose VJ (2014) Nucleic acid catalysis: metals, nucleobases, and other cofactors. Chem Rev 114:4318–4342
-
(2014)
Chem Rev
, vol.114
, pp. 4318-4342
-
-
Ward, W.L.1
Plakos, K.2
DeRose, V.J.3
-
42
-
-
0033010809
-
Crystal structure of a lead-dependent ribozyme revealing metal binding sites revelant to catalysis
-
COI: 1:CAS:528:DyaK1MXhs12rtLk%3D, PID: 10074945
-
Wedekind JE, McKay DB (1999) Crystal structure of a lead-dependent ribozyme revealing metal binding sites revelant to catalysis. Nat Struct Biol 6:261–268
-
(1999)
Nat Struct Biol
, vol.6
, pp. 261-268
-
-
Wedekind, J.E.1
McKay, D.B.2
-
43
-
-
0041464604
-
Crystal structure of the leadzyme at 1.8 Å resolution: metal ion binding and the implications for catalytic mechanism and allo site ion regulation
-
COI: 1:CAS:528:DC%2BD3sXls1Oqs7c%3D, PID: 12911297
-
Wedekind JE, McKay DB (2003) Crystal structure of the leadzyme at 1.8 Å resolution: metal ion binding and the implications for catalytic mechanism and allo site ion regulation. Biochemistry 42:9554–9563
-
(2003)
Biochemistry
, vol.42
, pp. 9554-9563
-
-
Wedekind, J.E.1
McKay, D.B.2
-
44
-
-
0017253651
-
Specific cleavages of pure tRNAs by plumbous ions
-
COI: 1:CAS:528:DyaE28Xhs1Skurs%3D, PID: 773433
-
Werner C, Krebs B, Keith G, Dirheimer G (1976) Specific cleavages of pure tRNAs by plumbous ions. Biochim Biophys Acta 432:161–175
-
(1976)
Biochim Biophys Acta
, vol.432
, pp. 161-175
-
-
Werner, C.1
Krebs, B.2
Keith, G.3
Dirheimer, G.4
-
46
-
-
79959503058
-
Metal ion sensors based on DNAzymes and related DNA molecules
-
COI: 1:CAS:528:DC%2BC3MXhtVynsbjF
-
Zhang X-B, Kong R-M, Lu Y (2011) Metal ion sensors based on DNAzymes and related DNA molecules. Annu Rev Anal Chem 4:105–128
-
(2011)
Annu Rev Anal Chem
, vol.4
, pp. 105-128
-
-
Zhang, X.-B.1
Kong, R.-M.2
Lu, Y.3
-
47
-
-
0042121256
-
Mfold web server for nucleic acid folding and hybridization prediction
-
COI: 1:CAS:528:DC%2BD3sXltVWisr8%3D, PID: 12824337
-
Zuker M (2003) Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res 31:3406–3415
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3406-3415
-
-
Zuker, M.1
|