Limitation of thiamine pyrophosphate supply to growing Escherichia coli switches metabolism to efficient d-lactate formation

Biotechnology and Bioengineering

Volumn 113, Issue 1, 2016, Pages 182-188

  Tian, Kangming ^a   Niu, Dandan ^b   Liu, Xiaoguang ^a   Prior, Bernard A ^c   Zhou, Li ^d   Lu, Fuping ^a   Singh, Suren ^e   Wang, Zhengxiang ^a  

^a TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b FUZHOU UNIVERSITY   (China)

^c STELLENBOSCH UNIVERSITY   (South Africa)

^d JIANGNAN UNIVERSITY   (China)

^e DURBAN UNIVERSITY OF TECHNOLOGY   (South Africa)

Author keywords

Cell replication; d lactate fermentation; Thiamine auxotroph

Indexed keywords

BIOCHEMISTRY; BIOREACTORS; CARBON; CELLS; CYTOLOGY; ESCHERICHIA COLI; FERMENTATION; GENE ENCODING; GROWTH KINETICS; METABOLISM;

BIOTECHNOLOGICAL PROCESS; CELL REPLICATION; D-LACTATE; ENGINEERED ESCHERICHIA COLI; MICROAEROBIC CONDITIONS; SHAKE-FLASK EXPERIMENTS; THIAMINE AUXOTROPH; THIAMINE MONOPHOSPHATE;

CELL GROWTH;

COCARBOXYLASE; LACTIC ACID; SYNTHETASE; THIAMINE; THIAMINE PHOSPHATE; THIAMINE PHOSPHATE SYNTHASE; UNCLASSIFIED DRUG; CULTURE MEDIUM;

ARTICLE; AUXOTROPHY; BACTERIAL METABOLISM; BACTERIAL STRAIN; BIOREACTOR; CALCULATION; CELL GROWTH; ESCHERICHIA COLI; FERMENTATION; GENE; MUTANT; NONHUMAN; CHEMISTRY; CULTURE MEDIUM; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLIC ENGINEERING; METABOLISM; PROCEDURES;

CULTURE MEDIA; ESCHERICHIA COLI; LACTIC ACID; METABOLIC ENGINEERING; THIAMINE PYROPHOSPHATE;

EID: 84948109810     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25699     Document Type: Article

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