Ultrahigh-speed, swept-source optical coherence tomography angiography in nonexudative age-related macular degeneration with geographic atrophy

Ophthalmology

Volumn 122, Issue 12, 2015, Pages 2532-2544

  Choi, Woojhon ^a   Moult, Eric M ^a,b   Waheed, Nadia K ^c   Adhi, Mehreen ^c   Lee, Byungkun ^a   Lu, Chen D ^a   De Carlo, Talisa E ^c   Jayaraman, Vijaysekhar ^d   Rosenfeld, Philip J ^e   Duker, Jay S ^c   Fujimoto, James G ^a  

^a Department of Electrical Engineering and Computer Science   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c TUFTS MEDICAL CENTER   (United States)

^d Praevium Research Inc   (United States)

^e UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

A SCAN; AGE RELATED MACULAR DEGENERATION; AGED; ARTICLE; CHOROID CAPILLARY LAYER; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; FEMALE; GEOGRAPHIC ATROPHY; HUMAN; IMAGE QUALITY; MALE; OBSERVATIONAL STUDY; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RETINA ANGIOGRAPHY; SIGNAL NOISE RATIO; SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY; ADULT; BLOOD FLOW; BLOOD FLOW VELOCITY; CHOROID; FLUORESCENCE ANGIOGRAPHY; MACULAR DEGENERATION; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; RETINA BLOOD VESSEL; VASCULARIZATION; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BLOOD FLOW VELOCITY; CHOROID; CROSS-SECTIONAL STUDIES; FEMALE; FLUORESCEIN ANGIOGRAPHY; GEOGRAPHIC ATROPHY; HUMANS; MACULAR DEGENERATION; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; REGIONAL BLOOD FLOW; RETINAL VESSELS; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84947996102     PISSN: 01616420     EISSN: 15494713     Source Type: Journal    
DOI: 10.1016/j.ophtha.2015.08.029     Document Type: Article

References (40)

1. J.P. Sarks, S.H. Sarks, and M.C. Killingsworth Evolution of geographic atrophy of the retinal-pigment epithelium Eye 2 1988 552 577
2. D.S. McLeod, R. Grebe, I. Bhutto, and et al. Relationship between RPE and choriocapillaris in age-related macular degeneration Invest Ophthalmol Vis Sci 50 2009 4982 4991
3. R.F. Mullins, M.N. Johnson, E.A. Faidley, and et al. Choriocapillaris vascular dropout related to density of drusen in human eyes with early age-related macular degeneration Invest Ophthalmol Vis Sci 52 2011 1606 1612
4. I. Bhutto, and G. Lutty Understanding age-related macular degeneration (AMD): relationships between the photoreceptor/retinal pigment epithelium/Bruch's membrane/choriocapillaris complex Mol Aspects Med 33 2012 295 317
5. A. Biesemeier, T. Taubitz, S. Julien, and et al. Choriocapillaris breakdown precedes retinal degeneration in age-related macular degeneration Neurobiol Aging 35 2014 2562 2573
6. R.F. Mullins, A. Khanna, D.P. Schoo, and et al. Is age-related macular degeneration a microvascular disease? J.D. Ash, C. Grimm, J.G. Hollyfield, Retinal Degenerative Diseases 801 2014 Springer New York 283 289
7. D.S. McLeod, M. Taomoto, T. Otsuji, and et al. Quantifying changes in RPE and choroidal vasculature in eyes with age-related macular degeneration Invest Ophthalmol Vis Sci 43 2002 1986 1993
8. P. Bischoff, and R. Flower Ten years experience with choroidal angiography using indocyanine green dye: a new routine examination or an epilogue? Doc Ophthalmol 60 1985 235 291
9. R.W. Flower Extraction of choriocapillaris hemodynamic data from ICG fluorescence angiograms Invest Ophthalmol Vis Sci 34 1993 2720 2729
10. L. Zhu, Y. Zheng, C.H. von Kerczek, and et al. Feasibility of extracting velocity distribution in choriocapillaris in human eyes from ICG dye angiograms J Biomech Eng 128 2005 203 209
11. S. Makita, Y. Hong, M. Yamanari, and et al. Optical coherence angiography Opt Express 14 2006 7821 7840
12. J. Fingler, D. Schwartz, C.H. Yang, and et al. Mobility and transverse flow visualization using phase variance contrast with spectral domain optical coherence tomography Opt Express 15 2007 12636 12653
13. Y.K. Tao, A.M. Davis, and J.A. Izatt Single-pass volumetric bidirectional blood flow imaging spectral domain optical coherence tomography using a modified Hilbert transform Opt Express 16 2008 12350 12361
14. L. An, and R.K.K. Wang In vivo volumetric imaging of vascular perfusion within human retina and choroids with optical micro-angiography Opt Express 16 2008 11438 11452
15. A. Mariampillai, B.A. Standish, E.H. Moriyama, and et al. Speckle variance detection of microvasculature using swept-source optical coherence tomography Opt Lett 33 2008 1530 1532
16. B.J. Vakoc, R.M. Lanning, J.A. Tyrrell, and et al. Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging Nat Med 15 2009 1219 1223
17. L.F. Yu, and Z.P. Chen Doppler variance imaging for three-dimensional retina and choroid angiography J Biomed Opt 15 2010 016029
18. E. Jonathan, J. Enfield, and M.J. Leahy Correlation mapping: rapid method for retrieving microcirculation morphology from optical coherence tomography intensity images V.V. Tuchin, D.D. Duncan, K.V. Larin, Dynamics and Fluctuations in Biomedical Photonics VIII 2011 SPIE San Francisco, CA
19. C. Blatter, T. Klein, B. Grajciar, and et al. Ultrahigh-speed non-invasive widefield angiography J Biomed Opt 17 2012 070505
20. D.Y. Kim, J. Fingler, R.J. Zawadzki, and et al. Optical imaging of the chorioretinal vasculature in the living human eye Proc Natl Acad Sci U S A 110 2013 14354 14359
21. D.M. Schwartz, J. Fingler, D.Y. Kim, and et al. Phase-variance optical coherence tomography: a technique for noninvasive angiography Ophthalmology 121 2014 180 187
22. I. Grulkowski, J.J. Liu, B. Potsaid, and et al. Retinal, anterior segment and full eye imaging using ultrahigh speed swept source OCT with vertical-cavity surface emitting lasers Biomed Opt Express 3 2012 2733 2751
23. W. Choi, B. Potsaid, V. Jayaraman, and et al. Phase-sensitive swept-source optical coherence tomography imaging of the human retina with a vertical cavity surface-emitting laser light source Opt Lett 38 2013 338 340
24. A. Unterhuber, B. Povazay, B. Hermann, and et al. In vivo retinal optical coherence tomography at 1040 nm-enhanced penetration into the choroid Opt Express 13 2005 3252 3258
25. M. Guizar-Sicairos, S.T. Thurman, and J.R. Fienup Efficient subpixel image registration algorithms Opt Lett 33 2008 156 158
26. J. Tokayer, Y. Jia, A.H. Dhalla, and et al. Blood flow velocity quantification using split-spectrum amplitude-decorrelation angiography with optical coherence tomography Biomed Opt Express 4 2013 1909 1924
27. S. Makita, F. Jaillon, M. Yamanari, and et al. Comprehensive in vivo micro-vascular imaging of the human eye by dual-beam-scan Doppler optical coherence angiography Opt Express 19 2011 1271 1283
28. R.S. Ramrattan, T.L. van der Schaft, C.M. Mooy, and et al. Morphometric analysis of Bruch's membrane, the choriocapillaris, and the choroid in aging Invest Ophthalmol Vis Sci 35 1994 2857 2864
29. R.W. Flower, C. von Kerczek, L. Zhu, and et al. Theoretical investigation of the role of choriocapillaris blood flow in treatment of subfoveal choroidal neovascularization associated with age-related macular degeneration Am J Ophthalmol 132 2001 85 93
30. E.M. Moult, W. Choi, N.K. Waheed, and et al. Ultrahigh-speed swept-source OCT angiography in exudative AMD Ophthalmic Surg Lasers Imaging Retina 45 2014 496 505
31. J.M. Olver Functional anatomy of the choroidal circulation: methyl methacrylate casting of human choroid Eye 4 1990 262 272
32. W. Choi, K.J. Mohler, B. Potsaid, and et al. Choriocapillaris and choroidal microvasculature imaging with ultrahigh speed OCT angiography PLoS One 8 2013 e81499
33. A. Abbey, A. Kuriyan, Y. Modi, and et al. Optical coherence tomography measurements of choroidal thickness in healthy eyes: correlation with age and axial length Ophthalmic Surg Lasers Imaging Retina 46 2015 18 24
34. R.F. Mullins, M.A. Grassi, and J.M. Skeie Glycoconjugates of choroidal neovascular membranes in age-related macular degeneration Mol Vis 11 2005 509 517
35. D.S. McLeod, and G.A. Lutty High-resolution histologic analysis of the human choroidal vasculature Invest Ophthalmol Vis Sci 35 1994 3799 3811
36. A.C. Bird, R.L. Phillips, and G.S. Hageman Geographic atrophy: a histopathological assessment JAMA Ophthalmol 132 2014 338 345
37. U.E.K. Wolf-Schnurrbusch, V. Enzmann, C.K. Brinkmann, and et al. Morphologic changes in patients with geographic atrophy assessed with a novel spectral OCT-SLO combination Invest Ophthalmol Vis Sci 49 2008 3095 3099
38. M. Fleckenstein, P.C. Issa, H.M. Helb, and et al. High-resolution spectral domain-OCT imaging in geographic atrophy associated with age-related macular degeneration Invest Ophthalmol Vis Sci 49 2008 4137 4144
39. J.S. Sunness, J. Gonzalez-Baron, N.M. Bressler, and et al. The development of choroidal neovascularization in eyes with the geographic atrophy form of age-related macular degeneration Ophthalmology 106 1999 910 919
40. B. Povazay, B. Hermann, A. Unterhuber, and et al. Three-dimensional optical coherence tomography at 1050 nm versus 800 nm in retinal pathologies: enhanced performance and choroidal penetration in cataract patients J Biomed Opt 12 2007 041211