Blood flow velocity quantification using splitspectrum amplitude-decorrelation angiography with optical coherence tomography

Biomedical Optics Express

Volumn 4, Issue 10, 2013, Pages 1909-1924

  Tokayer, Jason ^a   Jia, Yali ^b   Dhalla, Al Hafeez ^b,c,d   Huang, David ^b  

^a Ming Hsieh Department of Electrical Engineering University of Southern California ^*  (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c USA   (United States)

^d TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGRAPHY; HEMODYNAMICS; IMAGING TECHNIQUES; OPTICAL TOMOGRAPHY;

BLOOD FLOW VELOCITY; BLOOD VELOCITY; CLINICAL SETTINGS; LINEAR MODELING; MULTIPLE TIME SCALE; OPERATING RANGES; PHANTOM EXPERIMENT; PHASE INFORMATION;

FLOW VELOCITY;

ALGORITHM; ANGIOGRAPHY; ARTICLE; B SCAN; BIOLOGICAL MODEL; BLOOD FLOW VELOCITY; DATA PROCESSING; ERYTHROCYTE; LIGHT SCATTERING; OPTICAL COHERENCE TOMOGRAPHY; OPTICAL RESOLUTION; PHANTOM; SIGNAL NOISE RATIO; SPECTROMETRY; THEORY;

EID: 84884937817     PISSN: None     EISSN: 21567085     Source Type: Journal    
DOI: 10.1364/BOE.4.001909     Document Type: Article

References (56)

1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography, " Science 254(5035), 1178-1181 (1991).
2. M. R. Hee, J. A. Izatt, E. A. Swanson, D. Huang, J. S. Schuman, C. P. Lin, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography of the human retina, " Arch. Ophthalmol. 113(3), 325-332 (1995).
3. M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical coherence tomography, " J. Biomed. Opt. 7(3), 457-463 (2002).
4. B. White, M. Pierce, N. Nassif, B. Cense, B. Park, G. Tearney, B. Bouma, T. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical coherence tomography, " Opt. Express 11(25), 3490-3497 (2003).
5. J. Flammer, S. Orgül, V. P. Costa, N. Orzalesi, G. K. Krieglstein, L. M. Serra, J. P. Renard, and E. Stefánsson, "The impact of ocular blood flow in glaucoma, " Prog. Retin. Eye Res. 21(4), 359-393 (2002).
6. E. Friedman, "A hemodynamic model of the pathogenesis of age-related macular degeneration, " Am. J. Ophthalmol. 124(5), 677-682 (1997).
7. Y. Zhao, Z. Chen, C. Saxer, S. Xiang, J. F. de Boer, and J. S. Nelson, "Phase-resolved optical coherence tomography and optical Doppler tomography for imaging blood flow in human skin with fast scanning speed and high velocity sensitivity, " Opt. Lett. 25(2), 114-116 (2000).
8. V. X. D. Yang, M. L. Gordon, A. Mok, Y. Zhao, Z. Chen, R. S. C. Cobbold, B. C. Wilson, and I. Alex Vitkin, "Improved phase-resolved optical Doppler tomography using the Kasai velocity estimator and histogram segmentation, " Opt. Commun. 208(4-6), 209-214 (2002).
9. R. Leitgeb, L. Schmetterer, W. Drexler, A. Fercher, R. Zawadzki, and T. Bajraszewski, "Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography, " Opt. Express 11(23), 3116-3121 (2003).
10. M. A. Choma, A. K. Ellerbee, S. Yazdanfar, and J. A. Izatt, "Doppler flow imaging of cytoplasmic streaming using spectral domain phase microscopy, " J. Biomed. Opt. 11(2), 024014 (2006).
11. B. Baumann, B. Potsaid, M. F. Kraus, J. J. Liu, D. Huang, J. Hornegger, A. E. Cable, J. S. Duker, and J. G. Fujimoto, "Total retinal blood flow measurement with ultrahigh speed swept source/Fourier domain OCT, " Biomed. Opt. Express 2(6), 1539-1552 (2011).
12. R. Leitgeb, C. Hitzenberger, and A. Fercher, "Performance of fourier domain vs. time domain optical coherence tomography, " Opt. Express 11(8), 889-894 (2003).
13. H. C. Hendargo, R. P. McNabb, A. H. Dhalla, N. Shepherd, and J. A. Izatt, "Doppler velocity detection limitations in spectrometer-based versus swept-source optical coherence tomography, " Biomed. Opt. Express 2(8), 2175-2188 (2011).
14. R. K. Wang and Z. Ma, "Real-time flow imaging by removing texture pattern artifacts in spectral-domain optical Doppler tomography, " Opt. Lett. 31(20), 3001-3003 (2006).
15. Y. J. Hong, S. Makita, F. Jaillon, M. J. Ju, E. J. Min, B. H. Lee, M. Itoh, M. Miura, and Y. Yasuno, "Highpenetration swept source Doppler optical coherence angiography by fully numerical phase stabilization, " Opt. Express 20(3), 2740-2760 (2012).
16. H. Ren and X. Li, "Clutter rejection filters for optical Doppler tomography, " Opt. Express 14(13), 6103-6112 (2006).
17. J. Tokayer and D. Huang, "Effect of blood vessel diameter on relative blood flow estimates in Doppler optical coherence tomography algorithms, " Proc. SPIE 7889, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV, 78892X, 78892X-8 (2011).
18. Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "Retinal blood flow measurement by circumpapillary Fourier domain Doppler optical coherence tomography, " J. Biomed. Opt. 13(6), 064003 (2008).
19. M. Szkulmowski, A. Szkulmowska, T. Bajraszewski, A. Kowalczyk, and M. Wojtkowski, "Flow velocity estimation using joint Spectral and Time domain Optical Coherence Tomography, " Opt. Express 16(9), 6008-6025 (2008).
20. Y. K. Tao, A. M. Davis, and J. A. Izatt, "Single-pass volumetric bidirectional blood flow imaging spectral domain optical coherence tomography using a modified Hilbert transform, " Opt. Express 16(16), 12350-12361 (2008).
21. I. Grulkowski, I. Gorczynska, M. Szkulmowski, D. Szlag, A. Szkulmowska, R. A. Leitgeb, A. Kowalczyk, and M. Wojtkowski, "Scanning protocols dedicated to smart velocity ranging in spectral OCT, " Opt. Express 17(26), 23736-23754 (2009).
22. S. Makita, Y. Hong, M. Yamanari, T. Yatagai, and Y. Yasuno, "Optical coherence angiography, " Opt. Express 14(17), 7821-7840 (2006).
23. L. An and R. K. Wang, "In vivo volumetric imaging of vascular perfusion within human retina and choroids with optical micro-angiography, " Opt. Express 16(15), 11438-11452 (2008).
24. R. K. Wang, L. An, P. Francis, and D. J. Wilson, "Depth-resolved imaging of capillary networks in retina and choroid using ultrahigh sensitive optical microangiography, " Opt. Lett. 35(9), 1467-1469 (2010).
25. L. Yu and Z. Chen, "Doppler variance imaging for three-dimensional retina and choroid angiography, " J. Biomed. Opt. 15(1), 016029 (2010).
26. G. Liu, W. Qi, L. Yu, and Z. Chen, "Real-time bulk-motion-correction free Doppler variance optical coherence tomography for choroidal capillary vasculature imaging, " Opt. Express 19(4), 3657-3666 (2011).
27. J. Fingler, D. Schwartz, C. Yang, and S. E. Fraser, "Mobility and transverse flow visualization using phase variance contrast with spectral domain optical coherence tomography, " Opt. Express 15(20), 12636-12653 (2007).
28. B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, "Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging, " Nat. Med. 15(10), 1219-1223 (2009).
29. Y. Yasuno, Y. Hong, S. Makita, M. Yamanari, M. Akiba, M. Miura, and T. Yatagai, "In vivo high-contrast imaging of deep posterior eye by 1-um swept source optical coherence tomography and scattering optical coherence angiography, " Opt. Express 15(10), 6121-6139 (2007).
30. Y. Hong, S. Makita, M. Yamanari, M. Miura, S. Kim, T. Yatagai, and Y. Yasuno, "Three-dimensional visualization of choroidal vessels by using standard and ultra-high resolution scattering optical coherence angiography, " Opt. Express 15(12), 7538-7550 (2007).
31. A. Mariampillai, B. A. Standish, E. H. Moriyama, M. Khurana, N. R. Munce, M. K. K. Leung, J. Jiang, A. Cable, B. C. Wilson, I. A. Vitkin, and V. X. D. Yang, "Speckle variance detection of microvasculature using swept-source optical coherence tomography, " Opt. Lett. 33(13), 1530-1532 (2008).
32. H. C. Hendargo, R. Estrada, S. J. Chiu, C. Tomasi, S. Farsiu, and J. A. Izatt, "Automated non-rigid registration and mosaicing for robust imaging of distinct retinal capillary beds using speckle variance optical coherence tomography, " Biomed. Opt. Express 4(6), 803-821 (2013).
33. E. Jonathan, J. Enfield, and M. J. Leahy, "Correlation mapping method for generating microcirculation morphology from optical coherence tomography (OCT) intensity images, " J Biophotonics 4(9), 583-587 (2011).
34. Y. Jia, O. Tan, J. Tokayer, B. Potsaid, Y. Wang, J. J. Liu, M. F. Kraus, H. Subhash, J. G. Fujimoto, J. Hornegger, and D. Huang, "Split-spectrum amplitude-decorrelation angiography with optical coherence tomography, " Opt. Express 20(4), 4710-4725 (2012).
35. Y. Jia, J. C. Morrison, J. Tokayer, O. Tan, L. Lombardi, B. Baumann, C. D. Lu, W. Choi, J. G. Fujimoto, and D. Huang, "Quantitative OCT angiography of optic nerve head blood flow, " Biomed. Opt. Express 3(12), 3127-3137 (2012).
36. E. Wei, Y. Jia, O. Tan, B. Potsaid, J. J. Liu, W. Choi, J. G. Fujimoto, and D. Huang, "Parafoveal retinal vascular response to pattern visual stimulation assessed with OCT angiography, " PLoS ONE. submitted.
37. W. Li, C. T. Lancee, E. I. Cespedes, A. F. W. van der Steen, and N. Bom, "Decorrelation properties of intravascular echo signals: Potentials for blood velocity estimation, " J. Acoust. Soc. Am. 71(14), 70D-86D (1993).
38. W. Li, A. F. W. van der Steen, C. T. Lancée, I. Céspedes, and N. Bom, "Blood flow imaging and volume flow quantitation with intravascular ultrasound, " Ultrasound Med. Biol. 24(2), 203-214 (1998).
39. G. Liu, L. Chou, W. Jia, W. Qi, B. Choi, and Z. Chen, "Intensity-based modified Doppler variance algorithm: application to phase instable and phase stable optical coherence tomography systems, " Opt. Express 19(12), 11429-11440 (2011).
40. G. Liu, W. Jia, V. Sun, B. Choi, and Z. Chen, "High-resolution imaging of microvasculature in human skin invivo with optical coherence tomography, " Opt. Express 20(7), 7694-7705 (2012).
41. G. Liu, A. J. Lin, B. J. Tromberg, and Z. Chen, "A comparison of Doppler optical coherence tomography methods, " Biomed. Opt. Express 3(10), 2669-2680 (2012).
42. Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography, " J. Biomed. Opt. 12(4), 041215 (2007).
43. S. Makita, T. Fabritius, and Y. Yasuno, "Full-range, high-speed, high-resolution 1 μm spectral-domain optical coherence tomography using BM-scan for volumetric imaging of the human posterior eye, " Opt. Express 16(12), 8406-8420 (2008).
44. M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultrahighresolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation, " Opt. Express 12(11), 2404-2422 (2004).
45. A. Szkulmowska, M. Szkulmowski, A. Kowalczyk, and M. Wojtkowski, "Phase-resolved Doppler optical coherence tomography--limitations and improvements, " Opt. Lett. 33(13), 1425-1427 (2008).
46. S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Motion artifacts in optical coherence tomography with frequency-domain ranging, " Opt. Express 12(13), 2977-2998 (2004).
47. W. Li, C. T. Lancee, E. I. Cespedes, A. F. W. van der Steen, and N. Bom, "Decorrelation of intravascular ultrasound signals: A computer simulation study, " in Proceeding of IEEE Ultrasonics Symposium, 1997. Proceedings., 1997 IEEE(1997), pp. 1165-1168 vol.1162.
48. A. D. Poularikas and S. Seely, Signals and Systems (Krieger Publishing Co. 1991), Chap. 4.
49. S. Yazdanfar, C. Yang, M. V. Sarunic, and J. A. Izatt, "Frequency estimation precision in Doppler optical coherence tomography using the Cramer-Rao lower bound, " Opt. Express 13(2), 410-416 (2005).
50. M. L. Turgeon, Clinical Hematology: Theory and Procedures (Lippincott, Williams and Wilkins 2005). Chap. 6.
51. C. S. Kim, W. Qi, J. Zhang, Y. J. Kwon, and Z. Chen, "Imaging and quantifying Brownian motion of micro-and nanoparticles using phase-resolved Doppler variance optical coherence tomography, " J. Biomed. Opt. 18(3), 030504 (2013).
52. C. E. Riva and B. Petrig, "Blue field entoptic phenomenon and blood velocity in the retinal capillaries, " J. Opt. Soc. Am. 70(10), 1234-1238 (1980).
53. R. Flower, E. Peiretti, M. Magnani, L. Rossi, S. Serafini, Z. Gryczynski, and I. Gryczynski, "Observation of erythrocyte dynamics in the retinal capillaries and choriocapillaris using ICG-loaded erythrocyte ghost cells, " Invest. Ophthalmol. Vis. Sci. 49(12), 5510-5516 (2008).
54. J. Tam, P. Tiruveedhula, and A. Roorda, "Characterization of single-file flow through human retinal parafoveal capillaries using an adaptive optics scanning laser ophthalmoscope, " Biomed. Opt. Express 2(4), 781-793 (2011).
55. T. Klein, W. Wieser, C. M. Eigenwillig, B. R. Biedermann, and R. Huber, "Megahertz OCT for ultrawide-field retinal imaging with a 1050 nm Fourier domain mode-locked laser, " Opt. Express 19(4), 3044-3062 (2011).
56. B. Potsaid, V. Jayaraman, J. G. Fujimoto, J. Jiang, P. J. S. Heim, and A. E. Cable, "MEMS tunable VCSEL light source for ultrahigh speed 60kHz-1MHz axial scan rate and long range centimeter class OCT imaging, " Proc. SPIE 8213, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI, 82130M, 82130M-8 (2012).