Verification and refinement of cellular glycosphingolipid profiles using HPLC

Biochemistry and Cell Biology

Volumn 93, Issue 6, 2015, Pages 581-586

  Vieira, Douglas B ^a,c   Thur, Karen ^a   Sultana, Saki ^a   Priestman, David ^b   Van Der Spoel, Aarnoud C ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Immunovaccine Inc   (Canada)

Author keywords

Ceramide glycanase; Glycosphingolipids; HPLC; Lipidomics; Quantitative analysis

Indexed keywords

CELL CULTURE; CELL MEMBRANES; CELLS; CERAMIDES; CHEMICAL ANALYSIS; LIPIDS; VIRUSES;

CERAMIDE GLYCANASE; GLYCOSPHINGOLIPIDS; GROWTH FACTOR RECEPTORS; HPLC; HYBRID MOLECULES; LIPIDOMICS; MEMBRANE COMPONENTS; VIRAL PARTICLES;

CYTOLOGY;

GLYCOSPHINGOLIPID; ANTHRANILIC ACID; ANTHRANILIC ACID DERIVATIVE; CERAMIDE GLYCANASE; FLUORESCENT DYE; GLYCOSIDASE;

ANIMAL CELL; ARTICLE; COS 7 CELL LINE; FEMALE; HEK293 CELL LINE; HELA CELL LINE; HEPG2 CELL LINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; JURKAT CELL LINE; LIPID ANALYSIS; NONHUMAN; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; ANIMAL; CELL CULTURE; CELL LINE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; CHLOROCEBUS AETHIOPS; COMPARATIVE STUDY; CRICETULUS; ENZYMOLOGY; HIRUDO MEDICINALIS; HYDROLYSIS; METABOLISM; METABOLOMICS; MICROTECHNOLOGY; MOUSE; PROCEDURES; RAT; SPECTROFLUOROMETRY; TUMOR CELL LINE;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CELL MEMBRANE; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETULUS; FLUORESCENT DYES; GLYCOSIDE HYDROLASES; GLYCOSPHINGOLIPIDS; HIRUDO MEDICINALIS; HUMANS; HYDROLYSIS; METABOLOMICS; MICE; MICROTECHNOLOGY; MOLECULAR STRUCTURE; ORTHO-AMINOBENZOATES; RATS; SPECTROMETRY, FLUORESCENCE;

EID: 84947942561     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/bcb-2015-0074     Document Type: Article

References (37)

1. D'Angelo G. Capasso S. Sticco L. Russo D. 2013. Glycosphingolipids: synthesis and functions. FEBS J. 280 (24): 6338-6353. 10.1111/febs.12559. 24165035.
2. Debnath J. Muthuswamy S.K. Brugge J.S. 2003. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods, 30 (3): 256-268. 10.1016/S1046-2023(03)00032-X. 12798140.
3. Dennis E.A. 2009. Lipidomics joins the omics evolution. Proc. Natl. Acad. Sci. U.S.A. 106 (7): 2089-2090. 10.1073/pnas.0812636106. 19211786.
4. Ewers H. Helenius A. 2011. Lipid-mediated endocytosis. Cold Spring Harb. Perspect. Biol. 3 (8): a004721. 10.1101/cshperspect.a004721. 21576253.
5. Ferreira L. Villar E. Munoz-Barroso I. 2004. Gangliosides and N-glycoproteins function as Newcastle disease virus receptors. Int. J. Biochem. Cell Biol. 36 (11): 2344-2356. 10.1016/j.biocel.2004.05.011. 15313478.
6. Guan F. Handa K. Hakomori S.I. 2011. Regulation of epidermal growth factor receptor through interaction of ganglioside GM3 with GlcNAc of N-linked glycan of the receptor: demonstration in ldlD cells. Neurochem. Res. 36 (9): 1645-1653. 10.1007/s11064-010-0379-9. 21203834.
7. Hakomori, S., and Ishizuka, I. 2006. Glycolipids: Animal. eLS: John Wiley & Sons, Ltd. 10.1002/9780470015902.a0000706.pub2.
8. Hettmer S. Ladisch S. Kaucic K. 2005. Low complex ganglioside expression characterizes human neuroblastoma cell lines. Cancer Lett. 225 (1): 141-149. 10.1016/j.canlet.2004.11.036. 15922866.
9. Jennemann R. Grone H.J. 2013. Cell-specific in vivo functions of glycosphingolipids: lessons from genetic deletions of enzymes involved in glycosphingolipid synthesis. Prog. Lipid Res. 52 (2): 231-248. 10.1016/j.plipres.2013.02.001. 23473748.
10. Kabayama K. Sato T. Saito K. Loberto N. Prinetti A. Sonnino S. et al 2007. Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance. Proc. Natl. Acad. Sci. U.S.A. 104 (34): 13678-13683. 10.1073/pnas.0703650104. 17699617.
11. Kobata A. 1994. Size fractionation of oligosaccharides. Methods Enzymol. 230: 200-208. 10.1016/0076-6879(94)30013-5. 8139496.
12. Kolter T. Proia R.L. Sandhoff K. 2002. Combinatorial ganglioside biosynthesis. J. Biol. Chem. 277 (29): 25859-25862. 10.1074/jbc.R200001200. 12011101.
13. Kouzel I.U. Pohlentz G. Storck W. Radamm L. Hoffmann P. Bielaszewska M. et al 2013. Association of Shiga toxin glycosphingolipid receptors with membrane microdomains of toxin-sensitive lymphoid and myeloid cells. J. Lipid Res. 54 (3): 692-710. 10.1194/jlr.M031781. 23248329.
14. Li Y.T. Li S.C. 1989. Ceramide glycanase from leech, Hirudo medicinalis, and earthworm, Lumbricus terrestris. Methods Enzymol. 179: 479-487. 10.1016/0076-6879(89)79147-3. 2695772.
15. Merril A.H. Jr 2005. SphinGOMAP-a web-based biosynthetic pathway map of sphingolipids and glycosphingolipids. Glycobiology, 15 (6): 15G. 10.1093/glycob/cwi070. 15938018.
16. Mutoh T. Tokuda A. Miyadai T. Hamaguchi M. Fujiki N. 1995. Ganglioside GM1 binds to the Trk protein and regulates receptor function. Proc. Natl. Acad. Sci. U.S.A. 92 (11): 5087-5091. 10.1073/pnas.92.11.5087. 7539142.
17. Neville D.C. Coquard V. Priestman D.A. te Vruchte D.J. Sillence D.J. Dwek R.A. et al 2004. Analysis of fluorescently labeled glycosphingolipid-derived oligosaccharides following ceramide glycanase digestion and anthranilic acid labeling. Anal. Biochem. 331 (2): 275-282. 10.1016/j.ab.2004.03.051. 15265733.
18. Neville D.C. Dwek R.A. Butters T.D. 2009. Development of a single column method for the separation of lipid-and protein-derived oligosaccharides. J. Proteome Res. 8 (2): 681-687. 10.1021/pr800704t. 19099509.
19. Ohkawa Y. Momota H. Kato A. Hashimoto N. Tsuda Y. Kotani N. et al 2015. Ganglioside GD3 enhances invasiveness of gliomas by forming a complex with platelet-derived growth factor receptor α and Yes kinase. J. Biol. Chem. 290: 16043-16058. 10.1074/jbc.M114.635755. 25940087.
20. Park, M., Koppikar, A., Lee, R., Suzuki, A., Uyesugi, K., Wang, J., et al. 2004. SphinGOMAP. Available from http://www.sphingomap.org [accessed June 1, 2015].
21. Pei B. Speak A.O. Shepherd D. Butters T. Cerundolo V. Platt F.M. Kronenberg M. 2011. Diverse endogenous antigens for mouse NKT cells: self-antigens that are not glycosphingolipids. J. Immunol. 186 (3): 1348-1360. 10.4049/jimmunol.1001008. 21191069.
22. Puryear W.B. Yu X. Ramirez N.P. Reinhard B.M. Gummuluru S. 2012. HIV-1 incorporation of host-cell-derived glycosphingolipid GM3 allows for capture by mature dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 109 (19): 7475-7480. 10.1073/pnas.1201104109. 22529395.
23. Ravindran M.S. Tanner L.B. Wenk M.R. 2013. Sialic acid linkage in glycosphingolipids is a molecular correlate for trafficking and delivery of extracellular cargo. Traffic, 14 (11): 1182-1191. 10.1111/tra.12100. 23944656.
24. Rebhan M. Vacun G. Bayreuther K. Rosner H. 1994. Altered ganglioside expression by SH-SY5Y cells upon retinoic acid-induced neuronal differentiation. Neuroreport, 5 (8): 941-944. 10.1097/00001756-199404000-00022. 8061301.
25. Rosen K. Coll M.L. Li A. Filmus J. 2001. Transforming Growth Factor-α Prevents Detachment-induced Inhibition of c-Src Kinase Activity, Bcl-XLDown-regulation, and Apoptosis of Intestinal Epithelial Cells. J. Biol. Chem. 276 (40): 37273-37279. 10.1074/jbc.M106424200. 11487584.
26. Rosner H. 1998. Significance of gangliosides in neuronal differentiation of neuroblastoma cells and neurite growth in tissue culture. Ann. N.Y. Acad. Sci. 845: 200-214. 10.1111/j.1749-6632.1998.tb09672.x. 9668353.
27. Royle, L., Dwek, R.A., and Rudd, P.M. 2006. Determining the structure of oligosaccharides N-and O-linked to glycoproteins. Curr. Protoc. Protein Sci. Chapter 12: Unit 12.16. 10.1002/0471140864.ps1206s43. 18429295.
28. Ruan S. Lloyd K.O. 1992. Glycosylation pathways in the biosynthesis of gangliosides in melanoma and neuroblastoma cells: relative glycosyltransferase levels determine ganglioside patterns. Cancer Res 52: 5725-5731. 1394196.
29. Spence M.W. Cook H.W. Byers D.M. Palmer F.B. 1990. The role of sphingomyelin in phosphatidylcholine metabolism in cultured human fibroblasts from control and sphingomyelin lipidosis patients and in Chinese hamster ovary cells. Biochem. J. 268 (3): 719-724. 10.1042/bj2680719. 2363706.
30. Spitalnik P.F. Danley J.M. Burger S.R. Spitalnik S.L. 1989. The glycosphingolipid composition of the human hepatoma cell line, Hep-G2. Arch. Biochem. Biophys. 273 (2): 578-591. 10.1016/0003-9861(89)90518-3. 2549875.
31. Tatsumi K. Saito M. Lin B. Iwamori M. Ichiseki H. Shimozawa N. et al 2001. Enhanced expression of a-series gangliosides in fibroblasts of patients with peroxisome biogenesis disorders. Biochim. Biophys. Acta, 1535 (3): 285-293. 10.1016/S0925-4439(01)00027-8. 11278168.
32. Thorne P.C. Byers D.M. Palmer F.B. Cook H.W. 1994. Clofibrate and other peroxisomal proliferating agents relatively specifically inhibit synthesis of ethanolamine phosphoglycerides in cultured human fibroblasts. Biochim. Biophys. Acta, 1214 (2): 161-170. 10.1016/0005-2760(94)90040-X. 7918596.
33. van Meer G. 2005. Cellular lipidomics. EMBO J. 24 (18): 3159-3165. 10.1038/sj.emboj.7600798. 16138081.
34. Wang J. Yu R.K. 2013. Interaction of ganglioside GD3 with an EGF receptor sustains the self-renewal ability of mouse neural stem cells in vitro. Proc. Natl. Acad. Sci. U.S.A. 110 (47): 19137-19142. 10.1073/pnas.1307224110. 24198336.
35. Yamaji T. Hanada K. 2014. Establishment of HeLa cell mutants deficient in sphingolipid-related genes using TALENs. PLoS One, 9 (2): e88124. 10.1371/journal.pone.0088124. 24498430.
36. Yamaji T. Nishikawa K. Hanada K. 2010. Transmembrane BAX inhibitor motif containing (TMBIM) family proteins perturbs a trans-Golgi network enzyme, Gb3 synthase, and reduces Gb3 biosynthesis. J. Biol. Chem. 285 (46): 35505-35518. 10.1074/jbc.M110.154229. 20837469.
37. Yamamura S. Handa K. Hakomori S. 1997. A close association of GM3 with c-Src and Rho in GM3-enriched microdomains at the B16 melanoma cell surface membrane: a preliminary note. Biochem. Biophys. Res. Commun. 236 (1): 218-222. 10.1006/bbrc.1997.6933. 9223455.