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Angewandte Chemie - International Edition

Volumn 54, Issue 30, 2015, Pages 8700-8703

A Synthetic DNA-Binding Domain Guides Distinct Chromatin-Modifying Small Molecules to Activate an Identical Gene Network

(12) Han, Le a,b Pandian, Ganesh N c Chandran, Anandhakumar a Sato, Shinsuke c Taniguchi, Junichi a Kashiwazaki, Gengo a Sawatani, Yoshito a Hashiya, Kaori a Bando, Toshikazu a Xu, Yufang b Qian, Xuhong b Sugiyama, Hiroshi a,c

a KYOTO UNIVERSITY (Japan)

b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (China)

c KYOTO UNIVERSITY (Japan)

Author keywords

DNA recognition; epigenetics; gene expression; histone modification; synthetic biology

Indexed keywords

BINS; DNA; DNA SEQUENCES; ENZYME ACTIVITY; ENZYMES; GENES; IODINE; LIGANDS; MOLECULES;

DNA RECOGNITION; EPIGENETICS; HISTONE ACETYLTRANSFERASES; HISTONE DEACETYLASES; HISTONE MODIFICATION; SYNTHETIC BIOLOGY; SYNTHETIC STRATEGIES; TRANSCRIPTIONAL CONTROL;

GENE EXPRESSION;

BENZAMIDE DERIVATIVE; DNA; HISTONE; HISTONE ACETYLTRANSFERASE; MOLECULAR LIBRARY;

CELL LINE; CHEMISTRY; DRUG EFFECTS; GENE REGULATORY NETWORK; GENETIC EPIGENESIS; GENETICS; HUMAN; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY; PROTEIN TERTIARY STRUCTURE;

BENZAMIDES; CELL LINE; DNA; EPIGENESIS, GENETIC; GENE REGULATORY NETWORKS; HISTONE ACETYLTRANSFERASES; HISTONES; HUMANS; PROTEIN STRUCTURE, TERTIARY; SMALL MOLECULE LIBRARIES;

EID: 84947869809 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201503607 Document Type: Article

Times cited : (29)

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