Moderate peep after tracheal lipopolysaccharide instillation prevents inflammation and modifies the pattern of brain neuronal activation

Shock

Volumn 44, Issue 6, 2015, Pages 601-608

  Quilez, María Elisa ^a,b   Rodríguez González, Raquel ^c,d   Turon, Marc ^a,b   Fernandez Gonzalo, Sol ^a   Villar, Jesús ^b,d   Kacmarek, Robert M ^e,f   Gómez, Ma Nieves ^a   Oliva, Joan Carles ^a   Blanch, Lluís ^a,b   López Aguilar, Josefina ^a,b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^d HOSPITAL UNIVERSITARIO DE GRAN CANARIA DR NEGRÍN   (Spain)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f HARVARD UNIVERSITY   (United States)

Author keywords

Experimental; Inflammation; Mechanical ventilation; Neuronal activation; PEEP

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; PROTEIN C FOS;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ARTIFICIAL VENTILATION; BRAIN NERVE CELL; CELL ACTIVATION; CENTRAL NUCLEUS (AMYGDALA); CONTROLLED STUDY; EXPERIMENTAL INFLAMMATION; GAS EXCHANGE; LUNG MECHANICS; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PARAVENTRICULAR THALAMIC NUCLEUS; POSITIVE END EXPIRATORY PRESSURE; RAT; RETROSPLENIAL CORTEX; SOLITARY TRACT NUCLEUS; SUPRAOPTIC NUCLEUS; THALAMUS; ANIMAL; BRAIN; DRUG EFFECTS; GENE EXPRESSION REGULATION; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; METABOLISM; NERVE CELL; NEUTROPHIL; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; TRACHEA; TUNEL ASSAY;

ANIMALS; APOPTOSIS; BRAIN; GENE EXPRESSION REGULATION; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INFLAMMATION; LIPOPOLYSACCHARIDES; MALE; NEURONS; NEUTROPHILS; POSITIVE-PRESSURE RESPIRATION; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; TRACHEA;

EID: 84947868562     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000469     Document Type: Article

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