Auditory pathology in a transgenic mtTFB1 mouse model of mitochondrial deafness

American Journal of Pathology

Volumn 185, Issue 12, 2015, Pages 3132-3140

  McKay, Sharen E ^a,b   Yan, Wayne ^a   Nouws, Jessica ^a   Thormann, Maximilian J ^a   Raimundo, Nuno ^c   Khan, Abdul ^a   Santos Sacchi, Joseph ^a   Song, Lei ^a   Shadel, Gerald S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF BRIDGEPORT   (United States)

^c UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR E2F1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOCHONDRIAL DNA; TFB1M PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN STEM RESPONSE; CELL DEATH; COCHLEA DUCT; COCHLEA POTENTIAL; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME PHOSPHORYLATION; HEARING IMPAIRMENT; LATENT PERIOD; MITOCHONDRIAL DEAFNESS; MOUSE; NONHUMAN; OUTER HAIR CELL; PHENOTYPE; PRESBYACUSIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPIRAL GANGLION; STRIA VASCULARIS; UPREGULATION; ANIMAL; C57BL MOUSE; CORTI ORGAN; DEFICIENCY; DISEASE MODEL; EVOKED BRAIN STEM AUDITORY RESPONSE; GENETICS; INNER HAIR CELL; KNOCKOUT MOUSE; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REACTION TIME; TRANSGENIC MOUSE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; DEAFNESS; DISEASE MODELS, ANIMAL; DNA, MITOCHONDRIAL; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; HAIR CELLS, AUDITORY, INNER; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MITOCHONDRIAL DISEASES; MUTATION; ORGAN OF CORTI; REACTION TIME; SIGNAL TRANSDUCTION; SPIRAL GANGLION; STRIA VASCULARIS; TRANSCRIPTION FACTORS;

EID: 84947780742     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2015.08.014     Document Type: Article

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