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Volumn 9, Issue 9, 2014, Pages

Activation of cre recombinase alone can induce complete tumor regression

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; TAMOXIFEN; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; INTEGRASE; PROTEIN P53; UBIQUITIN C;

EID: 84947766593     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107589     Document Type: Article
Times cited : (20)

References (12)
  • 1
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    • Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxPmediated gene targeting
    • Gu H, Zou YR, Rajewsky K (1993) Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxPmediated gene targeting. Cell 73: 1155-1164.
    • (1993) Cell , vol.73 , pp. 1155-1164
    • Gu, H.1    Zou, Y.R.2    Rajewsky, K.3
  • 4
    • 0035949704 scopus 로고    scopus 로고
    • Delivery of the Cre recombinase by a self-deleting lentiviral vector: Efficient gene targeting in vivo
    • Pfeifer A, Brandon EP, Kootstra N, Gage FH, Verma IM (2001) Delivery of the Cre recombinase by a self-deleting lentiviral vector: efficient gene targeting in vivo. Proc Natl Acad Sci U S A 98: 11450-11455.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 11450-11455
    • Pfeifer, A.1    Brandon, E.P.2    Kootstra, N.3    Gage, F.H.4    Verma, I.M.5
  • 5
    • 21744436924 scopus 로고    scopus 로고
    • Practical range of effective dose for Cre recombinase-expressing recombinant adenovirus without cell toxicity in mammalian cells
    • Baba Y, Nakano M, Yamada Y, Saito I, Kanegae Y (2005) Practical range of effective dose for Cre recombinase-expressing recombinant adenovirus without cell toxicity in mammalian cells. Microbiol Immunol 49: 559-570.
    • (2005) Microbiol Immunol , vol.49 , pp. 559-570
    • Baba, Y.1    Nakano, M.2    Yamada, Y.3    Saito, I.4    Kanegae, Y.5
  • 6
    • 33748705967 scopus 로고    scopus 로고
    • High levels of Cre expression in neuronal progenitors cause defects in brain development leading to microencephaly and hydrocephaly
    • Forni PE, Scuoppo C, Imayoshi I, Taulli R, Dastru W, et al. (2006) High levels of Cre expression in neuronal progenitors cause defects in brain development leading to microencephaly and hydrocephaly. J Neurosci 26: 9593-9602.
    • (2006) J Neurosci , vol.26 , pp. 9593-9602
    • Forni, P.E.1    Scuoppo, C.2    Imayoshi, I.3    Taulli, R.4    Dastru, W.5
  • 7
    • 84888880795 scopus 로고    scopus 로고
    • Moderate and high amounts of tamoxifen in alphaMHC-MerCreMer mice induce a DNA damage response, leading to heart failure and death
    • Bersell K, Choudhury S, Mollova M, Polizzotti BD, Ganapathy B, et al. (2013) Moderate and high amounts of tamoxifen in alphaMHC-MerCreMer mice induce a DNA damage response, leading to heart failure and death. Dis Model Mech 6: 1459-1469.
    • (2013) Dis Model Mech , vol.6 , pp. 1459-1469
    • Bersell, K.1    Choudhury, S.2    Mollova, M.3    Polizzotti, B.D.4    Ganapathy, B.5
  • 9
    • 66949153645 scopus 로고    scopus 로고
    • Direct hematological toxicity and illegitimate chromosomal recombination caused by the systemic activation of CreERT2
    • Higashi AY, Ikawa T, Muramatsu M, Economides AN, Niwa A, et al. (2009) Direct hematological toxicity and illegitimate chromosomal recombination caused by the systemic activation of CreERT2. J Immunol 182: 5633-5640.
    • (2009) J Immunol , vol.182 , pp. 5633-5640
    • Higashi, A.Y.1    Ikawa, T.2    Muramatsu, M.3    Economides, A.N.4    Niwa, A.5
  • 10
    • 34250694086 scopus 로고    scopus 로고
    • Vagaries of conditional gene targeting
    • Schmidt-Supprian M, Rajewsky K (2007) Vagaries of conditional gene targeting. Nat Immunol 8: 665-668.
    • (2007) Nat Immunol , vol.8 , pp. 665-668
    • Schmidt-Supprian, M.1    Rajewsky, K.2
  • 11
    • 0026561121 scopus 로고
    • Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
    • Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery CA Jr, et al. (1992) Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356: 215-221.
    • (1992) Nature , vol.356 , pp. 215-221
    • Donehower, L.A.1    Harvey, M.2    Slagle, B.L.3    McArthur, M.J.4    Montgomery, C.A.5
  • 12
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    • Deletion of the developmentally essential gene ATR in adult mice leads to agerelated phenotypes and stem cell loss
    • Ruzankina Y, Pinzon-Guzman C, Asare A, Ong T, Pontano L, et al. (2007) Deletion of the developmentally essential gene ATR in adult mice leads to agerelated phenotypes and stem cell loss. Cell Stem Cell 1: 113-126.
    • (2007) Cell Stem Cell , vol.1 , pp. 113-126
    • Ruzankina, Y.1    Pinzon-Guzman, C.2    Asare, A.3    Ong, T.4    Pontano, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.