Overexpression of microRNA-30a-5p inhibits liver cancer cell proliferation and induces apoptosis by targeting MTDH/PTEN/AKT pathway

Tumor Biology

Volumn 37, Issue 5, 2016, Pages 5885-5895

  Li, Wen fang ^a   Dai, Hang ^a,c   Ou, Qin ^b   Zuo, Guo qing ^c   Liu, Chang an ^a  

^a THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

^b HUBEI UNIVERSITY OF MEDICINE   (China)

^c Chongqing Orthopedics Hospital of Traditional Chinese Medicine   (China)

Author keywords

Apoptosis; Hepatocellular carcinoma; Metadherin; miR 30a 5p; Proliferation

Indexed keywords

MICRORNA; MICRORNA 30A 5P; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; TUMOR MARKER; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; CELL ADHESION MOLECULE; MESSENGER RNA; MIRN30 MICRORNA, HUMAN; MTDH PROTEIN, HUMAN;

AKT GENE; ANALYTICAL EQUIPMENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL COUNTING KIT 8; CELL GROWTH; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DIAGNOSTIC KIT; DOWN REGULATION; FLOW CYTOMETRY; GENE OVEREXPRESSION; GENE SILENCING; GENE TARGETING; GENETIC TRANSFECTION; GROWTH INHIBITION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VIVO CULTURE; LIVER CANCER; LUCIFERASE ASSAY; MOUSE; MTDH GENE; NONHUMAN; ONCOGENE; POLYMERASE CHAIN REACTION SYSTEM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PTEN GENE; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SPECTROMETER; SPECTROPHOTOMETER; TUMOR GROWTH; WESTERN BLOTTING; 3' UNTRANSLATED REGION; ANIMAL; BINDING SITE; CHEMISTRY; DISEASE MODEL; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; HEP-G2 CELL LINE; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; RNA INTERFERENCE; TUMOR CELL LINE; TUMOR VOLUME;

3' UNTRANSLATED REGIONS; ANIMALS; APOPTOSIS; BASE SEQUENCE; BINDING SITES; CARCINOMA, HEPATOCELLULAR; CELL ADHESION MOLECULES; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MICE; MICRORNAS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84947721250     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-015-4456-1     Document Type: Article

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