Collagen-Derived N-Acetylated Proline-Glycine-Proline in Intervertebral Discs Modulates CXCR1/2 Expression and Activation in Cartilage Endplate Stem Cells to Induce Migration and Differentiation Toward a Pro-Inflammatory Phenotype

Stem Cells

Volumn 33, Issue 12, 2015, Pages 3558-3568

  Feng, Chencheng ^a   Zhang, Yang ^a   Yang, Minghui ^a   Huang, Bo ^a   Zhou, Yue ^a,b  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b NONE   (China)

Author keywords

Cartilage endplate stem cell; Degenerative disc; Migration; N Acetylated proline glycine proline; Pro inflammatory phenotype

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; ENDOGLIN; F ACTIN; GELATINASE B; N ACETYLATED PROLINE GLYCINE PROLINE; NEUTROPHIL COLLAGENASE; UNCLASSIFIED DRUG; COLLAGEN; OLIGOPEPTIDE;

ADULT; ANIMAL CELL; ARTICLE; CARTILAGE CELL; CARTILAGE ENDPLATE STEM CELL; CELL DIFFERENTIATION; CELL MIGRATION; CHEMOTAXIS; CLINICAL ARTICLE; CYTOKINE PRODUCTION; DISEASE COURSE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; INTRACELLULAR SIGNALING; NONHUMAN; NUCLEUS PULPOSUS; PROTEIN ACETYLATION; PROTEIN EXPRESSION; SPINDLE CELL; BIOSYNTHESIS; CARTILAGE; CELL MOTION; CHEMISTRY; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; STEM CELL;

ADULT; CARTILAGE; CELL DIFFERENTIATION; CELL MOVEMENT; COLLAGEN; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INTERVERTEBRAL DISC; MALE; MIDDLE AGED; OLIGOPEPTIDES; RECEPTORS, INTERLEUKIN-8A; RECEPTORS, INTERLEUKIN-8B; STEM CELLS;

EID: 84947712033     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2200     Document Type: Article

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