Expression and relationship of proinflammatory chemokine RANTES/CCL5 and cytokine IL-1 β in painful human intervertebral discs

Spine

Volumn 38, Issue 11, 2013, Pages 873-880

  Kepler, Christopher K ^a,b   Markova, Dessislava Z ^a   Dibra, Florian ^a   Yadla, Sanjay ^a   Vaccaro, Alexander R ^a,b   Risbud, Makarand V ^a   Albert, Todd J ^a,b   Anderson, David Greg ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b ROTHMAN INSTITUTE   (United States)

Author keywords

Back pain; Biology of disc degeneration; CCL5; Cytokine expression; Discogram; IL 1; IL 8; Intervertebral disc degeneration; RANTES

Indexed keywords

ALGINIC ACID; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR5; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; RANTES; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; AUTOPSY; CADAVER; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DISCOGENIC PAIN; DISKOGRAPHY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; PFIRRMANN GRADE; PHENOTYPE; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; T LYMPHOCYTE; UPREGULATION;

ADULT; AGED; ANIMALS; CATTLE; CELLS, CULTURED; CHEMOKINE CCL5; COHORT STUDIES; CULTURE MEDIA; FETAL BLOOD; GENE EXPRESSION; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; MIDDLE AGED; PAIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SERUM; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84879070496     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e318285ae08     Document Type: Article

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