The oral microbiome of denture wearers is influenced by levels of natural dentition

PLoS ONE

Volumn 10, Issue 9, 2015, Pages

  O'Donnell, Lindsay E ^a   Robertson, Douglas ^a   Nile, Christopher J ^a   Cross, Laura J ^a   Riggio, Marcello ^a   Sherriff, Andrea ^a   Bradshaw, David ^b   Lambert, Margaret ^b   Malcolm, Jennifer ^a   Buijs, Mark J ^c   Zaura, Egija ^c   Crielaard, Wim ^c   Brandt, Bernd W ^c   Ramage, Gordon ^a  

^a GLASGOW DENTAL HOSPITAL AND SCHOOL   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

POLYPEPTIDE ANTIBIOTIC AGENT; BACTERIAL DNA; FUNGAL DNA;

ACTINOBACTERIA; ADULT; ARTICLE; BACTERIUM IDENTIFICATION; CAMPYLOBACTER; CANDIDA ALBICANS; CANDIDA GLABRATA; CANDIDA TROPICALIS; COLONY FORMING UNIT; CONTROLLED STUDY; CORYNEBACTERIUM; DENTITION; DENTURE; DENTURE WEARER; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FUNGUS ISOLATION; FUSOBACTERIUM; GENE SEQUENCE; HOST PATHOGEN INTERACTION; HUMAN; LACTOBACILLUS; MALE; MICROBIAL DIVERSITY; MISCELLANEOUS NAMED GROUPS; MOUTH FLORA; NONHUMAN; PILOT STUDY; PREVOTELLA; ROTHIA; SALIVA ANALYSIS; SELENOMONAS; STREPTOCOCCUS; TAXONOMY; AGED; BACTERIAL PHENOMENA AND FUNCTIONS; BACTERIUM; CANDIDA; CLASSIFICATION; COMPARATIVE STUDY; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGY; MICROFLORA; MIDDLE AGED; MOUTH; PHYSIOLOGY; STOMATITIS; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BACTERIA; BACTERIAL PHYSIOLOGICAL PHENOMENA; CANDIDA; DENTURES; DNA, BACTERIAL; DNA, FUNGAL; FEMALE; HOST-PATHOGEN INTERACTIONS; HUMANS; MALE; MICROBIOTA; MIDDLE AGED; MOUTH; STOMATITIS, DENTURE;

EID: 84947484165     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0137717     Document Type: Article

References (64)

1. Guzmán JM, Pawliczko A, Beales S, Till C, Voelcker I. Ageing in the twenty-first century: a celebration and a challenge. 2012. United Nations Population Fund (UNFPA), New York, and Help Age International, London.
2. Muenz R. Aging and demographic change in european societies: main trends and alternative policy options. Societal Protection-The World Bank, 2007.
3. Griffin SO, Jones JA, Brunson D, Griffin PM, Bailey WD. Burden of oral disease among older adults and implications for public health priorities. American journal of public health. 2012; 102(3):411-8. doi: 10.2105/AJPH.2011.300362 PMID: 22390504; Pub Med Central PMCID: PMC3487659.
4. Meurman JH, Hamalainen P. Oral health and morbidity-implications of oral infections on the elderly. Gerodontology. 2006; 23(1):3-16. Epub 2006/01/26. doi: 10.1111/j.1741-2358.2006.00102.x PMID: 16433636.
5. Felton D, Cooper L, Duqum I, Minsley G, Guckes A, Haug S, et al. Evidence-based guidelines for the care and maintenance of complete dentures: a publication of the American College of Prosthodontists. Journal of prosthodontics: official journal of the American College of Prosthodontists. 2011; 20 Suppl 1: S1-S12. doi: 10.1111/j.1532-849X.2010.00683.x PMID: 21324026.
6. Petersen PE. The World Oral Health Report 2003: continuous improvement of oral health in the 21st century-the approach of the WHO Global Oral Health Programme. Community dentistry and oral epidemiology. 2003; 31 Suppl 1:3-23. PMID: 15015736.
7. Coulthwaite L, Verran J. Potential pathogenic aspects of denture plaque. British journal of biomedical science. 2007; 64(4):180-9. PMID: 18236742.
8. Shulman JD, Beach MM, Rivera-Hidalgo F. The prevalence of oral mucosal lesions in U.S. adults: data from the Third National Health and Nutrition Examination Survey, 1988-1994. Journal of the American Dental Association. 2004; 135(9):1279-86. PMID: 15493392.
9. Gendreau L, Loewy ZG. Epidemiology and etiology of denture stomatitis. Journal of prosthodontics: official journal of the American College of Prosthodontists. 2011; 20(4):251-60. Epub 2011/04/06. doi: 10.1111/j.1532-849X.2011.00698.x PMID: 21463383.
10. Jeganathan S, Lin CC. Denture stomatitis-a review of the aetiology, diagnosis and management. Australian dental journal. 1992; 37(2):107-14. Epub 1992/04/01. PMID: 1294074.
11. Newton A. Denture sore mouth. A possible etiology. Br dent J. 1962;(112:):357-60.
12. Salerno C, Pascale M, Contaldo M, Esposito V, Busciolano M, Milillo L, et al. Candida-associated denture stomatitis. Medicina Oral Patología Oral y Cirugia Bucal. 2011:e139-e43. doi: 10.4317/medoral. 16.e139
13. Morales DK, Hogan DA. Candida albicans interactions with bacteria in the context of human health and disease. PLoS pathogens. 2010; 6(4):e1000886. Epub 2010/05/06. doi: 10.1371/journal.ppat.1000886 PMID: 20442787; Pub Med Central PMCID: PMC2861711.
14. Shirtliff ME, Peters BM, Jabra-Rizk MA. Cross-kingdom interactions: Candida albicans and bacteria. FEMS microbiology letters. 2009; 299(1):1-8. Epub 2009/06/26. doi: 10.1111/j.1574-6968.2009. 01668.x PMID: 19552706.
15. Sumi Y, Miura H, Sunakawa M, Michiwaki Y, Sakagami N. Colonization of denture plaque by respiratory pathogens in dependent elderly. Gerodontology. 2002; 19(1):25-9. Epub 2002/08/08. PMID: 12164235.
16. Ealla KK, Ghanta SB, Motupalli NK, Bembalgi M, Madineni PK, Raju PK. Comparative analysis of colony counts of different species of oral streptococci in saliva of dentulous, edentulous and in those wearing partial and complete dentures. The journal of contemporary dental practice. 2013; 14(4):601-4. Epub 2013/12/07. PMID: 24309335.
17. Daniluk T, Fiedoruk K, Sciepuk M, Zaremba ML, Rozkiewicz D, Cylwik-Rokicka D, et al. Aerobic bacteria in the oral cavity of patients with removable dentures. Advances in medical sciences. 2006; 51 Suppl 1:86-90. Epub 2007/04/27. PMID: 17458066.
18. Sumi Y, Kagami H, Ohtsuka Y, Kakinoki Y, Haruguchi Y, Miyamoto H. High correlation between the bacterial species in denture plaque and pharyngeal microflora. Gerodontology. 2003; 20(2):84-7. Epub 2003/12/31. PMID: 14697018.
19. Nikawa H, Hamada T, Yamamoto T. Denture plaque-past and recent concerns. J Dent. 1998; 26 (4):299-304. doi: 10.1016/S0300-5712(97)00026-2 PMID: ISI:000073440000003.
20. Muller L, Pawelec G. Aging and immunity-impact of behavioral intervention. Brain, behavior, and immunity. 2014; 39:8-22. doi: 10.1016/j.bbi.2013.11.015 PMID: 24315935.
21. Castelo-Branco C, Soveral I. The immune system and aging: a review. Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology. 2014; 30(1):16-22. doi: 10.3109/09513590.2013.852531 PMID: 24219599.
22. Davidopoulou S, Diza E, Sakellari D, Menexes G, Kalfas S. Salivary concentration of free LL-37 in edentulism, chronic periodontitis and healthy periodontium. Archives of oral biology. 2013; 58(8):930-4. Epub 2013/06/20. doi: 10.1016/j.archoralbio.2013.01.003 PMID: 23778112.
23. Malcolm J, Sherriff A, Lappin DF, Ramage G, Conway DI, Macpherson LM, et al. Salivary antimicrobial proteins associate with age-related changes in streptococcal composition in dental plaque. Molecular oral microbiology. 2014; 29(6):284-93. doi: 10.1111/omi.12058 PMID: 24890264.
24. Watzinger F, Suda M, Preuner S, Baumgartinger R, Ebner K, Baskova L, et al. Real-time quantitative PCR assays for detection and monitoring of pathogenic human viruses in immunosuppressed pediatric patients. Journal of clinical microbiology. 2004; 42(11):5189-98. doi: 10.1128/JCM.42.11.5189-5198. 2004 PMID: 15528714; Pub Med Central PMCID: PMC525141.
25. Caporaso JG, Lauber CL, Walters WA, Berg-Lyons D, Lozupone CA, Turnbaugh PJ, et al. Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample. Proceedings of the National Academy of Sciences of the United States of America. 2011; 108 Suppl 1:4516-22. Epub 2010/06/11. doi: 10.1073/pnas.1000080107 PMID: 20534432; Pub Med Central PMCID: PMCPmc3063599.
26. Kozich JJ, Westcott SL, Baxter NT, Highlander SK, Schloss PD. Development of a dual-index sequencing strategy and curation pipeline for analyzing amplicon sequence data on the MiSeq Illumina sequencing platform. Applied and environmental microbiology. 2013; 79(17):5112-20. doi: 10.1128/AEM.01043-13 PMID: 23793624; Pub Med Central PMCID: PMC3753973.
27. Caporaso JG, Lauber CL, Walters WA, Berg-Lyons D, Huntley J, Fierer N, et al. Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms. The ISME journal. 2012; 6 (8):1621-4. doi: 10.1038/ismej.2012.8 PMID: 22402401; Pub Med Central PMCID: PMC3400413.
28. (Oxford, England). Bolger AM, Lohse M, Usadel B. Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics (Oxford, England). 2014; 30(15):2114-20. Epub 2014/04/04. doi: 10.1093/bioinformatics/btu170 PMID: 24695404; Pub Med Central PMCID: PMCPmc4103590.
29. Caporaso JG, Kuczynski J, Stombaugh J, Bittinger K, Bushman FD, Costello EK, et al. QIIME allows analysis of high-throughput community sequencing data. Nature methods. 2010; 7(5):335-6. doi: 10.1038/nmeth.f.303 PMID: 20383131; Pub Med Central PMCID: PMC3156573.
30. Edgar RC. UPARSE: highly accurate OTU sequences from microbial amplicon reads. Nature methods. 2013; 10(10):996-8. doi: 10.1038/nmeth.2604 PMID: 23955772.
31. Cole JR, Wang Q, Cardenas E, Fish J, Chai B, Farris RJ, et al. The Ribosomal Database Project: improved alignments and new tools for rRNA analysis. Nucleic acids research. 2009; 37(Database issue):D141-5. Epub 2008/11/14. doi: 10.1093/nar/gkn879 PMID: 19004872; Pub Med Central PMCID: PMCPmc2686447.
32. Hans M, Madaan Hans V. Epithelial antimicrobial peptides: guardian of the oral cavity. International journal of peptides. 2014; 2014:370297. Epub 2014/12/02. doi: 10.1155/2014/370297 PMID: 25435884; Pub Med Central PMCID: PMCPmc4243596.
33. Dale BA, Fredericks LP. Antimicrobial peptides in the oral environment: expression and function in health and disease. Current issues in molecular biology. 2005; 7(2):119-33. Epub 2005/08/02. PMID: 16053246; Pub Med Central PMCID: PMCPmc1479858.
34. Peters BM, Zhu J, Fidel PL Jr., Scheper MA, Hackett W, El Shaye S, et al. Protection of the oral mucosa by salivary histatin-5 against Candida albicans in an ex vivo murine model of oral infection. FEMS yeast research. 2010; 10(5):597-604. Epub 2010/05/25. doi: 10.1111/j.1567-1364.2010.00632.x PMID: 20491938; Pub Med Central PMCID: PMCPmc2921938.
35. Hammer O, Harper D, Ryan PD. PAST: Paleontological statistics software package for education and data analysis.2001; (4:):[1-9 pp.].
36. Trends in aging-United States and worldwide. MMWR Morbidity and mortality weekly report. 2003; 52 (6):101-4, 6. Epub 2003/03/21. PMID: 12645839.
37. Petersen PE, Bourgeois D, Ogawa H, Estupinan-Day S, Ndiaye C. The global burden of oral diseases and risks to oral health. Bulletin of the World Health Organization. 2005; 83(9):661-9. doi:/S0042-96862005000900011. PMID: 16211157; Pub Med Central PMCID: PMC2626328.
38. Divaris K, Ntounis A, Marinis A, Polyzois G, Polychronopoulou A. Loss of natural dentition: multi-level effects among a geriatric population. Gerodontology. 2012; 29(2):e192-9. doi: 10.1111/j.1741-2358. 2010.00440.x PMID: 21083739.
39. Pereira-Cenci T, Del Bel Cury AA, Crielaard W, Ten Cate JM. Development of Candida-associated denture stomatitis: new insights. Journal of applied oral science: revista FOB. 2008; 16(2):86-94. PMID: 19089197.
40. Lamfon H, Al-Karaawi Z, McCullough M, Porter SR, Pratten J. Composition of in vitro denture plaque biofilms and susceptibility to antifungals. FEMS microbiology letters. 2005; 242(2):345-51. Epub 2004/12/29. doi: 10.1016/j.femsle.2004.11.032 PMID: 15621458.
41. Campos MS, Marchini L, Bernardes LA, Paulino LC, Nobrega FG. Biofilm microbial communities of denture stomatitis. Oral microbiology and immunology. 2008; 23(5):419-24. Epub 2008/09/17. doi: 10.1111/j.1399-302X.2008.00445.x PMID: 18793366.
42. Sachdeo A, Haffajee AD, Socransky SS. Biofilms in the edentulous oral cavity. Journal of prosthodontics: official journal of the American College of Prosthodontists. 2008; 17(5):348-56. Epub 2008/03/22. doi: 10.1111/j.1532-849X.2008.00301.x PMID: 18355168.
43. Teles FR, Teles RP, Sachdeo A, Uzel NG, Song XQ, Torresyap G, et al. Comparison of microbial changes in early redeveloping biofilms on natural teeth and dentures. Journal of periodontology. 2012; 83(9):1139-48. Epub 2012/03/27. doi: 10.1902/jop.2012.110506 PMID: 22443543; Pub Med Central PMCID: PMC4041159.
44. Wade WG. The oral microbiome in health and disease. Pharmacological research: the official journal of the Italian Pharmacological Society. 2013; 69(1):137-43. doi: 10.1016/j.phrs.2012.11.006 PMID: 23201354.
45. Aas JA, Paster BJ, Stokes LN, Olsen I, Dewhirst FE. Defining the normal bacterial flora of the oral cavity. Journal of clinical microbiology. 2005; 43(11):5721-32. doi: 10.1128/JCM.43.11.5721-5732.2005 PMID: 16272510; Pub Med Central PMCID: PMC1287824.
46. Diaz PI, Chalmers NI, Rickard AH, Kong C, Milburn CL, Palmer RJ Jr., et al. Molecular characterization of subject-specific oral microflora during initial colonization of enamel. Applied and environmental microbiology. 2006; 72(4):2837-48. doi: 10.1128/AEM.72.4.2837-2848.2006 PMID: 16597990; Pub Med Central PMCID: PMC1449052.
47. Zaura E, Keijser BJ, Huse SM, Crielaard W. Defining the healthy "core microbiome" of oral microbial communities. BMC microbiology. 2009; 9:259. doi: 10.1186/1471-2180-9-259 PMID: 20003481; Pub Med Central PMCID: PMC2805672.
48. Humphrey SP, Williamson RT. A review of saliva: normal composition, flow, and function. The Journal of prosthetic dentistry. 2001; 85(2):162-9. doi: 10.1067/mpr.2001.113778 PMID: 11208206.
49. Diamond G, Beckloff N, Ryan LK. Host Defense Peptides in the Oral Cavity and the Lung: Similarities and Differences. Journal of dental research. 2008; 87(10):915-27. PMID: PMC2730219.
50. Bingle CD, Gorr SU. Host defense in oral and airway epithelia: chromosome 20 contributes a new protein family. The international journal of biochemistry & cell biology. 2004; 36(11):2144-52. Epub 2004/08/18. doi: 10.1016/j.biocel.2004.05.002 PMID: 15313462.
51. Dickinson BC, Moffatt CE, Hagerty D, Whitmore SE, Brown TA, Graves DT, et al. Interaction of oral bacteria with gingival epithelial cell multilayers. Molecular oral microbiology. 2011; 26(3):210-20. Epub 2011/05/07. doi: 10.1111/j.2041-1014.2011.00609.x PMID: 21545698; Pub Med Central PMCID: PMCPmc3248246.
52. Signat B, Roques C, Poulet P, Duffaut D. Fusobacterium nucleatum in periodontal health and disease. Current issues in molecular biology. 2011; 13(2):25-36. Epub 2011/01/12. PMID: 21220789.
53. Kinane DF, Galicia JC, Gorr SU, Stathopoulou PG, Benakanakere M. P. gingivalis interactions with epithelial cells. Frontiers in bioscience: a journal and virtual library. 2008; 13:966-84. Epub 2007/11/06. PMID: 17981604.
54. Pfaller MA, Castanheira M, Lockhart SR, Ahlquist AM, Messer SA, Jones RN. Frequency of decreased susceptibility and resistance to echinocandins among fluconazole-resistant bloodstream isolates of Candida glabrata. Journal of clinical microbiology. 2012; 50(4):1199-203. doi: 10.1128/JCM.06112-11 PMID: 22278842; Pub Med Central PMCID: PMC3318516.
55. Lewis JS 2nd, Wiederhold NP, Wickes BL, Patterson TF, Jorgensen JH. Rapid emergence of echinocandin resistance in Candida glabrata resulting in clinical and microbiologic failure. Antimicrobial agents and chemotherapy. 2013; 57(9):4559-61. doi: 10.1128/AAC.01144-13 PMID: 23817368; Pub Med Central PMCID: PMC3754289.
56. Klingspor L, Tortorano AM, Peman J, Willinger B, Hamal P, Sendid B, et al. Invasive Candida infections in surgical patients in intensive care units: a prospective, multicentre survey initiated by the European Confederation of Medical Mycology (ECMM) (2006-2008). Clinical microbiology and infection: the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 2015; 21 (1):87 e1-e10. doi: 10.1016/j.cmi.2014.08.011 PMID: 25636940.
57. Alves CT, Wei XQ, Silva S, Azeredo J, Henriques M, Williams DW. Candida albicans promotes invasion and colonisation of Candida glabrata in a reconstituted human vaginal epithelium. The Journal of infection. 2014; 69(4):396-407. doi: 10.1016/j.jinf.2014.06.002 PMID: 24924556.
58. Kraneveld EA, Buijs MJ, Bonder MJ, Visser M, Keijser BJ, Crielaard W, et al. The relation between oral Candida load and bacterial microbiome profiles in Dutch older adults. PloS one. 2012; 7(8):e42770. Epub 2012/08/18. doi: 10.1371/journal.pone.0042770 PMID: 22900048; Pub Med Central PMCID: PMC3416775.
59. Orsi CF, Sabia C, Ardizzoni A, Colombari B, Neglia RG, Peppoloni S, et al. Inhibitory effects of different lactobacilli on Candida albicans hyphal formation and biofilm development. Journal of biological regulators and homeostatic agents. 2014; 28(4):743-52. PMID: 25620183.
60. Bilhan H, Sulun T, Erkose G, Kurt H, Erturan Z, Kutay O, et al. The role of Candida albicans hyphae and Lactobacillus in denture-related stomatitis. Clinical oral investigations. 2009; 13(4):363-8. doi: 10.1007/s00784-008-0240-6 PMID: 19101740.
61. Jiang Q, Stamatova I, Kari K, Meurman JH. Inhibitory activity in vitro of probiotic lactobacilli against oral Candida under different fermentation conditions. Beneficial microbes. 2014:1-8. doi: 10.3920/BM2014. 0054 PMID: 25380800.
62. Visvanathan V, Nix P. Managing the patient presenting with xerostomia: a review. International journal of clinical practice. 2010; 64(3):404-7. Epub 2009/10/13. doi: 10.1111/j.1742-1241.2009.02132.x PMID: 19817913.
63. Radek K, Gallo R. Antimicrobial peptides: natural effectors of the innate immune system. Seminars in immunopathology. 2007; 29(1):27-43. PMID: 17621952.
64. Bals R. Epithelial antimicrobial peptides in host defense against infection. Respiratory research. 2000; 1(3):141-50. doi: 10.1186/rr25 PMID: 11667978; Pub Med Central PMCID: PMC59560.