Interaction of oral bacteria with gingival epithelial cell multilayers

Molecular Oral Microbiology

Volumn 26, Issue 3, 2011, Pages 210-220

  Dickinson, B C ^a   Moffatt, C E ^b   Hagerty, D ^a   Whitmore, S E ^b   Brown, T A ^a   Graves, D T ^c   Lamont, R J ^b  

^a UNIVERSITY OF FLORIDA COLLEGE OF DENTISTRY   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Oral commensals; Oral pathogens; Periodontal disease; Virulence

Indexed keywords

CYTOKERATIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

AGGREGATIBACTER ACTINOMYCETEMCOMITANS; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL DIVISION; CELL INTERACTION; CELL MEMBRANE; CELL MOTION; CONFOCAL MICROSCOPY; ELECTRIC RESISTANCE; FLUORESCENT ANTIBODY TECHNIQUE; FUSOBACTERIUM NUCLEATUM; HUMAN; HUMAN TISSUE; MOUTH FLORA; MOUTH MUCOSA; NONHUMAN; PORPHYROMONAS GINGIVALIS; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; STREPTOCOCCUS GORDONII;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; APOPTOSIS; BACTERIA; CELL CULTURE TECHNIQUES; EPITHELIAL ATTACHMENT; EPITHELIAL CELLS; FUSOBACTERIUM NUCLEATUM; GINGIVA; HOST-PATHOGEN INTERACTIONS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; KERATIN-13; KERATIN-9; MICROSCOPY, CONFOCAL; MOUTH MUCOSA; PERIODONTAL DISEASES; PORPHYROMONAS GINGIVALIS; STREPTOCOCCUS GORDONII; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79955718494     PISSN: 20411006     EISSN: 20411014     Source Type: Journal    
DOI: 10.1111/j.2041-1014.2011.00609.x     Document Type: Article

References (43)

1. Andrian, E., Grenier, D. and Rouabhia, M. (2004) In vitro models of tissue penetration and destruction by Porphyromonas gingivalis. Infect Immun 72: 4689-4698.
2. Balkovetz, D.F. and Katz, J. (2003) Bacterial invasion by a paracellular route: divide and conquer. Microbes Infect 5: 613-619.
3. Belton, C.M., Izutsu, K.T., Goodwin, P.C., Park, Y. and Lamont, R.J. (1999) Fluorescence image analysis of the association between Porphyromonas gingivalis and gingival epithelial cells. Cell Microbiol 1: 215-223.
4. Darveau, R.P., Belton, C.M., Reife, R.A. and Lamont, R.J. (1998) Local chemokine paralysis, a novel pathogenic mechanism for Porphyromonas gingivalis. Infect Immun 66: 1660-1665.
5. Dixon, D.R., Reife, R.A., Cebra, J.J. and Darveau, R.P. (2004) Commensal bacteria influence innate status within gingival tissues: a pilot study. J Periodontol 75: 1486-1492.
6. Dzink, J.L., Socransky, S.S. and Haffajee, A.D. (1988) The predominant cultivable microbiota of active and inactive lesions of destructive periodontal diseases. J Clin Periodontol 15: 316-323.
7. Edwards, A.M., Grossman, T.J. and Rudney, J.D. (2006) Fusobacterium nucleatum transports noninvasive Streptococcus cristatus into human epithelial cells. Infect Immun 74: 654-662.
8. Guentsch, A., Ronnebeck, M., Puklo, M., Preshaw, P.M., Pfister, W. and Eick, S. (2010) Influence of serum on interaction of Porphyromonas gingivalis ATCC 33277 and Aggregatibacter actinomycetemcomitans Y4 with an epithelial cell line. J Periodontal Res 45: 229-238.
9. Hajishengallis, G. (2009) Porphyromonas gingivalis-host interactions: open war or intelligent guerilla tactics? Microbes Infect 11: 637-645.
10. Han, Y.W., Shi, W., Huang, G.T. et al. (2000) Interactions between periodontal bacteria and human oral epithelial cells: Fusobacterium nucleatum adheres to and invades epithelial cells. Infect Immun 68: 3140-3146.
11. Handfield, M., Mans, J.J., Zheng, G. et al. (2005) Distinct transcriptional profiles characterize oral epithelium-microbiota interactions. Cell Microbiol 7: 811-823.
12. Handfield, M., Baker, H.V. and Lamont, R.J. (2008) Beyond good and evil in the oral cavity: insights into host-microbe relationships derived from transcriptional profiling of gingival cells. J Dent Res 87: 203-223.
13. Hasegawa, Y., Mans, J.J., Mao, S. et al. (2007) Gingival epithelial cell transcriptional responses to commensal and opportunistic oral microbial species. Infect Immun 75: 2540-2547.
14. Hintermann, E., Haake, S.K., Christen, U., Sharabi, A. and Quaranta, V. (2002) Discrete proteolysis of focal contact and adherens junction components in Porphyromonas gingivalis-infected oral keratinocytes: a strategy for cell adhesion and migration disabling. Infect Immun 70: 5846-5856.
15. Huang, G.T., Haake, S.K. and Park, N.H. (1998) Gingival epithelial cells increase interleukin-8 secretion in response to Actinobacillus actinomycetemcomitans challenge. J Periodontol 69: 1105-1110.
16. Huang, G.T., Zhang, H.B., Dang, H.N. and Haake, S.K. (2004) Differential regulation of cytokine genes in gingival epithelial cells challenged by Fusobacterium nucleatum and Porphyromonas gingivalis. Microb Pathog 37: 303-312.
17. Kachlany, S.C. (2010) Aggregatibacter actinomycetemcomitans leukotoxin: from threat to therapy. J Dent Res 89: 561-570.
18. Kagnoff, M.F. and Eckmann, L. (1997) Epithelial cells as sensors for microbial infection. J Clin Invest 100: 6-10.
19. Katz, J., Sambandam, V., Wu, J.H., Michalek, S.M. and Balkovetz, D.F. (2000) Characterization of Porphyromonas gingivalis-induced degradation of epithelial cell junctional complexes. Infect Immun 68: 1441-1449.
20. Katz, J., Yang, Q.B., Zhang, P. et al. (2002) Hydrolysis of epithelial junctional proteins by Porphyromonas gingivalis gingipains. Infect Immun 70: 2512-2518.
21. Kuboniwa, M. and Lamont, R.J. (2010) Subgingival biofilm formation. Periodontol 2000: 38-52.
22. La, V.D., Howell, A.B. and Grenier, D. (2010) Anti-Porphyromonas gingivalis and anti-inflammatory activities of A-type cranberry proanthocyanidins. Antimicrob Agents Chemother 54: 1778-1784.
23. Lamont, R.J. and Jenkinson, H.F. (1998) Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalis. Microbiol Mol Biol Rev 62: 1244-1263.
24. Lamont, R.J., Chan, A., Belton, C.M., Izutsu, K.T., Vasel, D. and Weinberg, A. (1995) Porphyromonas gingivalis invasion of gingival epithelial cells. Infect Immun 63: 3878-3885.
25. Mao, S., Park, Y., Hasegawa, Y. et al. (2007) Intrinsic apoptotic pathways of gingival epithelial cells modulated by Porphyromonas gingivalis. Cell Microbiol 9: 1997-2007.
26. Marsh, P.D. (2003) Are dental diseases examples of ecological catastrophes? Microbiology 149: 279-294.
27. Meyer, D.H., Mintz, K.P. and Fives-Taylor, P.M. (1997) Models of invasion of enteric and periodontal pathogens into epithelial cells: a comparative analysis. Crit Rev Oral Biol Med 8: 389-409.
28. Moore, W.E. and Moore, L.V. (1994) The bacteria of periodontal diseases. Periodontol 2000: 66-77.
29. Nakhjiri, S.F., Park, Y., Yilmaz, O. et al. (2001) Inhibition of epithelial cell apoptosis by Porphyromonas gingivalis. FEMS Microbiol Lett 200: 145-149.
30. Nobbs, A.H., Shearer, B.H., Drobni, M., Jepson, M.A. and Jenkinson, H.F. (2007) Adherence and internalization of Streptococcus gordonii by epithelial cells involves beta1 integrin recognition by SspA and SspB (antigen I/II family) polypeptides. Cell Microbiol 9: 65-83.
31. Nobbs, A.H., Lamont, R.J. and Jenkinson, H.F. (2009) Streptococcus adherence and colonization. Microbiol Mol Biol Rev 73: 407-450.
32. Oda, D. and Watson, E. (1990) Human oral epithelial cell culture I. Improved conditions for reproducible culture in serum-free medium. In Vitro Cell Dev Biol 26: 589-595.
33. Pan, Y.M., Firth, J.D., Salonen, J.I. and Uitto, V.J. (1995) Multilayer culture of periodontal ligament epithelial cells: a model for junctional epithelium. J Periodontal Res 30: 97-107.
34. Papaioannou, W., Cassiman, J.J., Van den Oord, J., De Vos, R., van Steenberghe, D. and Quirynen, M. (1999) Multi-layered periodontal pocket epithelium reconstituted in vitro: histology and cytokeratin profiles. J Periodontol 70: 668-678.
35. Papaioannou, W., van Steenberghe, D., Cassiman, J.J., Dierickx, K. and Quirynen, M. (2003) Adhesion of Porphyromonas gingivalis to cultured pocket epithelium: mono- and multi-layered. Clin Oral Investig 7: 162-166.
36. Rouabhia, M. and Deslauriers, N. (2002) Production and characterization of an in vitro engineered human oral mucosa. Biochem Cell Biol 80: 189-195.
37. Sandros, J., Papapanou, P.N., Nannmark, U. and Dahlen, G. (1994) Porphyromonas gingivalis invades human pocket epithelium in vitro. J Periodontal Res 29: 62-69.
38. Stathopoulou, P.G., Benakanakere, M.R., Galicia, J.C. and Kinane, D.F. (2010) Epithelial cell pro-inflammatory cytokine response differs across dental plaque bacterial species. J Clin Periodontol 37: 24-29.
39. Stinson, M.W., Alder, S. and Kumar, S. (2003) Invasion and killing of human endothelial cells by viridans group streptococci. Infect Immun 71: 2365-2372.
40. Tanner, A. and Bouldin, H. (1989) The microbiota of early periodontitis lesions in adults. J Clin Periodontol 16: 467-471.
41. Tribble, G.D. and Lamont, R.J. (2010) Bacterial invasion of epithelial cells and spreading in periodontal tissue. Periodontol 2000: 68-83.
42. Xia, Q., Wang, T., Taub, F. et al. (2007) Quantitative proteomics of intracellular Porphyromonas gingivalis. Proteomics 7: 4323-4337.
43. Yilmaz, O., Verbeke, P., Lamont, R.J. and Ojcius, D.M. (2006) Intercellular spreading of Porphyromonas gingivalis infection in primary gingival epithelial cells. Infect Immun 74: 703-710.