Thermosensitive Hydrogel System with Paclitaxel Liposomes Used in Localized Drug Delivery System for in Situ Treatment of Tumor: Better Antitumor Efficacy and Lower Toxicity

Journal of Pharmaceutical Sciences

Volumn 105, Issue 1, 2016, Pages 194-204

  Mao, Yuling ^a   Li, Xue ^a   Chen, Ge ^b   Wang, Shujun ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

biodegradable polymers; cancer chemotherapy; controlled release; injectables; intratumoral retention; lymphatic transport; paclitaxel liposome; pharmacodynamics; thermal gels; thermosensitive; tissue distribution

Indexed keywords

LIPOSOME; PACLITAXEL; ANTINEOPLASTIC AGENT; DELAYED RELEASE FORMULATION; HYDROGEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CANCER TISSUE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG RETENTION; HEAT SENSITIVITY; HYDROGEL; IN VITRO STUDY; MORPHOLOGY; MOUSE; NONHUMAN; PANCREAS CANCER; PARTICLE SIZE; PRECIPITATION; TOXICITY; TRANSITION TEMPERATURE; ANIMAL; DELAYED RELEASE FORMULATION; DRUG SCREENING; DRUG STABILITY; HUMAN; MALE; MEDICINAL CHEMISTRY; NEOPLASMS; SARCOMA 180;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; HUMANS; HYDROGELS; LIPOSOMES; MALE; MICE; NEOPLASMS; PACLITAXEL; PARTICLE SIZE; SARCOMA 180; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84947461387     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.24693     Document Type: Article

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