Whole-genome sequencing suggests schizophrenia risk mechanisms in humans with 22q11.2 deletion syndrome

G3: Genes, Genomes, Genetics

Volumn 5, Issue 11, 2015, Pages 2453-2461

  Merico, Daniele ^a   Zarrei, Mehdi ^a   Costain, Gregory ^b,c   Ogura, Lucas ^b   Alipanahi, Babak ^c   Gazzellone, Matthew J ^a   Butcher, Nancy J ^b   Thiruvahindrapuram, Bhooma ^a   Nalpathamkalam, Thomas ^a   Chow, Eva W C ^b,c   Andrade, Danielle M ^c,d   Frey, Brendan J ^c   Marshall, Christian R ^a   Scherer, Stephen W ^a,d   Bassett, Anne S ^b,c,e,f  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY HEALTH NETWORK   (Canada)

^f TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

22q11 deletion syndrome; ABLIM1; BSN; Connectivity; Copy number variation; DGCR8; DIP2A; EXOC4; FMR1; Genetic architecture; ITM2C; LincRNA; MicroRNA; MYH10; MYH9; Next generation sequencing; Noncoding RNA; PCNT; Polygenic risk score; Postsynaptic density; PTPRG; Schizophrenia; SLITRK2; Synapse; ZDHHC5

Indexed keywords

UNTRANSLATED RNA; DGCR8 PROTEIN, HUMAN; LONG UNTRANSLATED RNA; RNA BINDING PROTEIN;

ADULT; ARTICLE; CHROMOSOME DELETION; CHROMOSOME DELETION 22Q11.2; CLINICAL ARTICLE; CONTROLLED STUDY; COPY NUMBER VARIATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC CODE; GENETIC MODEL; GENETIC RISK; HUMAN; PHENOTYPE; SCHIZOPHRENIA; ADOLESCENT; CASE CONTROL STUDY; COMPLICATION; DIGEORGE SYNDROME; FEMALE; GENETICS; HUMAN GENOME; MALE; MIDDLE AGED;

ADOLESCENT; ADULT; CASE-CONTROL STUDIES; DIGEORGE SYNDROME; FEMALE; GENOME, HUMAN; HUMANS; MALE; MIDDLE AGED; RNA, LONG NONCODING; RNA-BINDING PROTEINS; SCHIZOPHRENIA;

EID: 84947442427     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.115.021345     Document Type: Article

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