Mechanisms of glyceryl trinitrate provoked mast cell degranulation

Cephalalgia

Volumn 35, Issue 14, 2015, Pages 1287-1297

  Pedersen, Sara Hougaard ^a   Ramachandran, Roshni ^a   Amrutkar, Dipak Vasantrao ^a   Petersen, Steffen ^a   Olesen, Jes ^a   Jansen Olesen, Inger ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Dural mast cell; L nitro arginine methyl ester; migraine; nitric oxide; rat glyceryl trinitrate infusion model; sumatriptan

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; GLYCERYL TRINITRATE; L 733560; N(G) NITROARGININE METHYL ESTER; NITROPRUSSIDE SODIUM; OLCEGEPANT; PROTEIN C FOS; SUBSTANCE P; SUMATRIPTAN; NITRIC OXIDE DONOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DURA MATER; EX VIVO STUDY; HEADACHE; HORMONE RELEASE; IN VIVO STUDY; MALE; MAST CELL DEGRANULATION; NONHUMAN; RAT; VASODILATATION; ANIMAL; CHEMICALLY INDUCED; DEGRANULATION; DRUG EFFECTS; MAST CELL; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; CELL DEGRANULATION; HEADACHE; MALE; MAST CELLS; NITRIC OXIDE DONORS; NITROGLYCERIN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84947435056     PISSN: 03331024     EISSN: 14682982     Source Type: Journal    
DOI: 10.1177/0333102415574846     Document Type: Article

References (41)

1. Artico M, Cavallotti C,. Catecholaminergic and acetylcholine esterase containing nerves of cranial and spinal dura mater in humans and rodents. Microsc Res Tech 2001; 53: 212-220.
2. Varatharaj a, Mack J, Davidson JR, et al. Mast cells in the human dura: effects of age and dural bleeding. Childs Nerv Syst 2012; 28: 541-545.
3. Dimlich RV, Keller JT, Strauss TA, et al. Linear arrays of homogeneous mast cells in the dura mater of the rat. J Neurocytol 1991; 20: 485-503.
4. Rozniecki JJ, Dimitriadou V, Lambracht-Hall M, et al. Morphological and functional demonstration of rat dura mater mast cell-neuron interactions in vitro and in vivo. Brain Res 1999; 849: 1-15.
5. Strassman AM, Weissner W, Williams M, et al. Axon diameters and intradural trajectories of the dural innervation in the rat. J Comp Neurol 2004; 473: 364-376.
6. Ottosson A, Edvinsson L,. Release of histamine from dural mast cells by substance P and calcitonin gene-related peptide. Cephalalgia 1997; 17: 166-174.
7. Kulka M, Sheen CH, Tancowny BP, et al. Neuropeptides activate human mast cell degranulation and chemokine production. Immunology 2008; 123: 398-410.
8. Baun M, Pedersen MHF, Olesen J, et al. Dural mast cell degranulation is a putative mechanism for headache induced by PACAP-38. Cephalalgia 2012; 32: 337-345.
9. Levy D, Burstein R, Kainz V, et al. Mast cell degranulation activates a pain pathway underlying migraine headache. Pain 2007; 130: 166-176.
10. Thomsen LL, Kruuse C, Iversen HK, et al. A nitric oxide donor (nitroglycerin) triggers genuine migraine attacks. Eur J Neurol 1994; 1: 73-80.
11. Christiansen I, Thomsen L, Daugaard D, et al. Glyceryl trinitrate induces attacks of migraine without aura in sufferers of migraine with aura. Cephalalgia 1999; 19: 660-667.
12. Iversen HK, Olesen J, Tfelt-Hansen P,. Intravenous nitroglycerin as an experimental model of vascular headache. Basic characteristics. Pain 1989; 38: 17-24.
13. Lassen L, Ashina M, Christiansen I, et al. Nitric oxide synthase inhibition in migraine. Lancet 1997; 349: 401-402.
14. Reuter U, Bolay H, Jansen-Olesen I, et al. Delayed inflammation in rat meninges: implications for migraine pathophysiology. Brain 2001; 124: 2490-2502.
15. Tfelt-Hansen P, Daugaard D, Lassen LH, et al. Prednisolone reduces nitric oxide-induced migraine. Eur J Neurol 2009; 16(: 1106-1111.
16. Ramachandran R, Bhatt DK, Ploug KB, et al. A naturalistic glyceryl trinitrate infusion migraine model in the rat. Cephalalgia 2012; 32: 73-84.
17. Ramachandran R, Bhatt DK, Ploug KB, et al. Nitric oxide synthase, calcitonin gene-related peptide and NK-1 receptor mechanisms are involved in GTN-induced neuronal activation. Cephalalgia 2014; 34: 136-147.
18. Strecker T, Dux M, Messlinger K,. Nitric oxide releases calcitonin-gene-related peptide from rat dura mater encephali promoting increases in meningeal blood flow. J Vasc Res 2003; 39: 489-496.
19. Williamson D, Hargreaves R, Hill R, et al. Sumatriptan inhibits neurogenic vasodilation of dural blood vessels in the anaesthetized rat-intravital microscope studies. Cephalalgia 1997; 17: 525-531.
20. Jansen-Olesen I, Mortensen CH, El-Bariaki N, et al. Characterization of K(ATP)-channels in rat basilar and middle cerebral arteries: studies of vasomotor responses and mRNA expression. Eur J Pharmacol 2005; 523: 109-118.
21. Lassen LH, Ashina M, Christiansen I, et al. Nitric oxide synthase inhibition: a new principle in the treatment of migraine attacks. Cephalalgia 1998; 18: 27-32.
22. Ioannides C, Parke D, Taylor I,. Elimination of glyceryl trinitrate: effects of sex, age, species and route of administration. Br J Pharmacol 1982; 77: 83-88.
23. Dvorak A, Schleimer R, Lichtenstein L,. Human mast cells synthesize new granules during recovery from degranulation. In vitro studies with mast cells purified from human lungs. Blood 1988; 71: 76-85.
24. Burwen SJ,. Recycling of mast cells following degranulation in vitro: An ultrastructural study. Tissue Cell 1982; 14: 125-134.
25. Koulchitsky S, Fischer MJM, Messlinger K,. Calcitonin gene-related peptide receptor inhibition reduces neuronal activity induced by prolonged increase in nitric oxide in the rat spinal trigeminal nucleus. Cephalalgia 2008; 29: 408-417.
26. Zhang X, Kainz V, Zhao J, et al. Vascular extracellular signal-regulated kinase mediates migraine-related sensitization of meningeal nociceptors. Ann Neurol 2013; 73: 741-750.
27. Markowitz S, Saito K, Moskowitz M,. Neurogenically mediated leakage of plasma protein occurs from blood vessels in dura mater but not brain. J Neurosci 1987; 7: 4129-4136.
28. Moskowitz MA,. The neurobiology of vascular head pain. Ann Neurol 1984; 16: 157-168.
29. Murray DB, Gardner JD, Brower GL, et al. Endothelin-1 mediates cardiac mast cell degranulation, matrix metalloproteinase activation, and myocardial remodeling in rats. Am J Physiol Heart Circ Physiol 2004; 287: H2295-H2299.
30. Schwenger N, Dux M, de Col R, et al. Interaction of calcitonin gene-related peptide, nitric oxide and histamine release in neurogenic blood flow and afferent activation in the rat cranial dura mater. Cephalalgia 2007; 27: 481-491.
31. Read SJ, Manning P, McNeil CJ, et al. Effects of sumatriptan on nitric oxide and superoxide balance during glyceryl trinitrate infusion in the rat. Implications for antimigraine mechanisms. Brain Res 1999; 847: 1-8.
32. Kaube H, Hoskin KL, Goadsby PJ,. Inhibition by sumatriptan of central trigeminal neurones only after blood-brain barrier disruption. Br J Pharmacol 1993; 109: 788-792.
33. Arvieu L, Mauborgne A, Bourgoin S,. Sumatriptan inhibits the release of CGRP and substance P from the rat spinal cord. Neuroreport 1996; 7: 1973-1976.
34. Jiménez-Trejo F, Tapia-Rodríguez M, Queiroz DBC, et al. Serotonin concentration, synthesis, cell origin, and targets in the rat caput epididymis during sexual maturation and variations associated with adult mating status: morphological and biochemical studies. J Androl 2007; 28: 136-149.
35. Strassman A, Levy D,. The anti-migraine agent sumatriptan induces a calcium-dependent discharge in meningeal sensory neurons. Neuroreport 2004; 15: 1409-1412.
36. Ikeda Y, Jimbo H, Shimazu MS, et al. Sumatriptan scavenges superoxide, hydroxyl, and nitric oxide radicals: in vitro electron spin resonance study. Headache 2002; 42: 888-892.
37. Eftekhari S, Warfvinge K, Blixt FW, et al. Differentiation of nerve fibers storing CGRP and CGRP receptors in the peripheral trigeminovascular system. J Pain 2013; 14: 1289-1303.
38. Eltorp CT, Jansen-Olesen I, Hansen AJ,. Release of calcitonin gene-related peptide (CGRP) from guinea pig dura mater in vitro is inhibited by sumatriptan but unaffected by nitric oxide. Cephalalgia 2000; 20: 838-844.
39. Eberhardt M, Dux M, Namer B, et al. H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway. Nat Commun 2014; 5: 4381-4381.
40. Offenhauser N, Zinck T, Hoffmann J, et al. CGRP release and c-fos expression within trigeminal nucleus caudalis of the rat following glyceryltrinitrate infusion. Cephalalgia 2005; 25: 225-236.
41. Kruuse C, Iversen H, Jansen-Olesen I, et al. Calcitonin gene-related peptide (CGRP) levels during glyceryl trinitrate (GTN)-induced headache in healthy volunteers. Cephalalgia 2010; 30: 467-474.