Glyceryl trinitrate induces attacks of migraine without aura in sufferers of migraine with aura

Cephalalgia

Volumn 19, Issue 7, 1999, Pages 660-667

  Christiansen, I ^a   Thomsen, L L ^a   Daugaard, D ^a   Ulrich, V ^a   Olesen, J ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Glyceryl trinitrate; Headache; Migraine; Migraine with aura; Nitric oxide

Indexed keywords

GLYCERYL TRINITRATE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL EXAMINATION; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; FEMALE; HEADACHE; HUMAN; MALE; MIGRAINE; PAIN ASSESSMENT; SPREADING CORTICAL DEPRESSION;

ADULT; ANALGESICS; FEMALE; HEMODYNAMIC PROCESSES; HUMANS; MALE; MIGRAINE WITH AURA; MIGRAINE WITHOUT AURA; NITRIC OXIDE; NITROGLYCERIN; PAIN MEASUREMENT; TIME FACTORS;

EID: 0032877717     PISSN: 03331024     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1468-2982.1999.019007660.x     Document Type: Article

References (38)

1. Olesen J, Larsen B, Lauritzen M. Focal hypermia followed by spreading oligemia and impaired activation of rCBF in classic migraine. Arm Neurol 1981;9:344-52
2. Olesen J, Tfelt-Hansen P, Henriksen L, Larsen B. The common migraine attack may not be initiated by cerebral ischaemia. Lancet 1981;2:438-40
3. Olesen J. Cerebral and extracranial circulatory disturbances in migraine: pathophysiological implications. Cerebrovasc Brain Metab Rev 1991;3:1-28
4. Rasmussen BK. Migraine with aura and migraine without aura are two different entities. Cephalalgia 1995;15:183-6
5. Rasmussen BK, Olesen J. Migraine with aura and migraine without aura: an epidemiological study. Cephalalgia 1992;12:221-8
6. Russell MB, Rasmussen BK, Fenger K, Olesen J. Migraine without aura and migraine with aura are distinct clinical entities: a study of 484 male and female migraineurs from the general population. Cephalalgia 1996;16:239-45
7. Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991;43:109-41
8. Thomsen LL, Iversen HK, Lassen LH, Olesen J. The role of nitric oxide in migraine pain. CNS Drugs 1994;2:417-22
9. Feelish M, Noack EA. Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase. Eur J Pharmacol 1987;139:19-30
10. Thomsen LL, Kruuse C, Iversen HK, Olesen J. A nitric oxide donor (nitroglycerin) triggers genuine migraine attacks. Eur J Neurol 1994;1:73-80
11. Olean J, Iversen HK, Thomsen LL. Nitric oxide super-sensitivity: a possible molecular mechanism of migraine. Neuroreport 1993;27:1027-30
12. Lassen LH, Ashina M, Christiansen I, Ulrich V, Grover R, Donaldson J, Olesen J. Nitric oxide synthase inhibition: a new principle in the treatment of migraine attacks. Cephalalgia 1998;18:27-32
13. Headache Classification Committee of the International Headache Society. Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain. Cephalalgia 1988;8 Suppl 7:1-96
14. Iversen HK, Olesen J, Tfelt-Hansen P. Intravenous nitroglycerin as an experimental model of vascular headache. Basic characteristics. Pain 1989;38:17-24
15. Ebright GE. The effects of nitroglycerin on those engaged in its manufacture. JAMA 1914;62:201-2
16. Schwartz AM. The cause, relief and prevention of headaches rising from contact with dynamite. N Engl J Med 1946;235:541-4
17. Sicuteri F, Del Bene E, Poggioni M, Bonazzi A. Unmasking latent dysnociception in healthy subjects. Headache 1987;27:180-5
18. Thomsen LL, Iversen H, Brinck TA, Olesen J. Arterial supersensitivity to nitric oxide (nitroglycerin) in migraine sufferers. Cephalalgia 1993;13:395-9
19. Ignarro LJ, Lipton H, Edwards JC, Baricos WH, Hyman AL, Kadowitz PJ, et al. Mechanisms of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates. J Pharmacol Exp Ther 1981;218:739-49
20. Nichols FT III, Mawad M, Mohr JP, Stein B, Hilal S, Michelsen J. Focal headache during balloon inflation in the internal carotid and middle cerebral arteries. Stroke 1990;21:555-9
21. Friberg L., Olesen J., Iversen H.K., Sperling B. Migraine pain associated with middle cerebral artery dilatation: reversal by sumatriptan. Lancet 1991;338:13-7
22. Thomsen LL, Iversen HK, Olesen J. Cerebral blood flow velocities are reduced during attacks of unilateral migraine without aura. Cephalalgia 1995;15:109-16
23. Thomsen LL. Investigations into the role of nitric oxide and the large intracranial arteries in migraine headache. Cephalalgia 1997;17:973-95
24. Hibbs JB, Taintor RR, Vavrin Z, Rachlin EM. Nitric oxide: a cytotoxic activated macrophage effector molecule. Biochem Biophys Res Commun 1988;157:87-94
25. Lauritzen M. Pathophysiology of the migraine aura. The spreading depression theory. Brain 1994;117:199-210
26. Avoli M, Drapeau C, Louvel J, Pumain R, Olivier A, Villemure J-G. Epileptiform activity induced by low extra-cellular magnesium in the human cortex maintained in vitro. Ann Neurol 1991;30:589-96
27. Mayevsky A, Doron A, Manor T, Meilin S, Salame K, Quaknine GE. Repetitive cortical spreading depression cycle development in the human brain: a multiparametric monitoring approach. J Cereb Blood Flow Metab 1995;15 Suppl 1:S34
28. Curtis DR, Watkins JC: Analogues of glutamic acid and g-amino-n-butyric acids having potent actions on mammalian neurons. Nature 1961;191:1010-1
29. Garthwaite J, Charles SL, Chess-Williams R. Endothelium-derived relaxing factor release on activation of NMDA receptor suggests a role as intercellular messenger in the brain. Nature 1988;336:385-8
30. Chopp M, Chen Q, Zhang ZG, Bodzin G, Welch KMA. Nitric oxide synthase is induced in cerebral endothelial cells by spreading depression. Cephalalgia 1993;13 Suppl 13:117
31. Read SJ, Smith MI, Hunter AJ, Parsons AA. Measurement of nitric oxide release using a selective microelectrode following repeated waves of cortical spreading depression. Br J Pharmacol 1996;118:79P
32. Wahl M, Parson AA, Schilling L, Kaumann. Reduction of pial arterial dilatation during cortical spreading depression by local application of an inhibitor of nitric oxide synthesis. J Cereb Blood Flow Metab 1993;13 Suppl 1:S177
33. Goadsby PJ, Kaube H, Hoskin KL. Nitric oxide synthesis couples cerebral blood flow and metabolism. Brain Res 1992;595:167-70
34. Read SJ, Smith MI, Hunter AJ, Parsons AA. Enhanced nitric oxide release during cortical spreading depression following infusion of glyceryl trinitrate in the anaesthetized cat. Cephalalgia 1997;17:159-65
35. Tassorelli C, Joseph SA. Systemic nitroglycerin induces Fos immunoreactivity in brainstem and forebrain structures of the rat. Brain Res 1995;682:167-81
36. Warner M, Stromstedt M, Wyss A, Gustafsson JA. Regulation of cytocrome P450 in the central nervous system. J Steroid Biochem Mol Biol 1993;47:191-4
37. Marks GS, McLaughlin BE, Nakatsu K, Brein JF. Biotransformation of glyceryl trinitrate by rat brain homogenate. Can J Physiol Pharmacol 1992;70:935-7
38. Castellano AE, Micieli G, Bellantonio P, Buzzi MG, Marcheselli S, Pompeo F, et al. Indomethacin increases the effect of isosorbide dinitrate on cerebral hemodynamic in migraine patients: pathogenic and therapeutic implications. Cephalalgia 1998;18:622-30