-
1
-
-
84914167700
-
Alkaloids as drug leads-A predictive structural and biodiversity-based analysis
-
Amirkia, V., and Heinrich, M. (2014). Alkaloids as drug leads-A predictive structural and biodiversity-based analysis. Phytochem. Lett. 10, xlviii-liii. doi: 10.1016/j.phytol.2014.06.015
-
(2014)
Phytochem. Lett
, vol.10
, pp. xlviii-liii
-
-
Amirkia, V.1
Heinrich, M.2
-
2
-
-
36348987143
-
The value of natural products to future pharmaceutical discovery
-
Baker, D. D., Chu, M., Oza, U., and Rajgarhia, V. (2007). The value of natural products to future pharmaceutical discovery. Nat. Prod. Rep. 24, 1225-1244. doi: 10.1039/b602241n
-
(2007)
Nat. Prod. Rep
, vol.24
, pp. 1225-1244
-
-
Baker, D.D.1
Chu, M.2
Oza, U.3
Rajgarhia, V.4
-
3
-
-
27844474247
-
Drug discovery from medicinal plants
-
Balunas, M. J., and Kinghorn, A. D. (2005). Drug discovery from medicinal plants. Life Sci. 78, 431-441. doi: 10.1016/j.lfs.2005.09.012
-
(2005)
Life Sci
, vol.78
, pp. 431-441
-
-
Balunas, M.J.1
Kinghorn, A.D.2
-
4
-
-
77956395112
-
Natural products in modern life science
-
Bohlin, L., Göransson, U., Alsmark, C., Wedén, C., and Backlund, A. (2010). Natural products in modern life science. Phytochem. Rev. 9, 279-301. doi: 10.1007/s11101-009-9160-6
-
(2010)
Phytochem. Rev
, vol.9
, pp. 279-301
-
-
Bohlin, L.1
Göransson, U.2
Alsmark, C.3
Wedén, C.4
Backlund, A.5
-
5
-
-
11344292132
-
The role of natural product chemistry in drug discovery
-
Butler, M. S. (2004). The role of natural product chemistry in drug discovery. J. Nat. Prod. 67, 2141-2153. doi: 10.1021/np040106y
-
(2004)
J. Nat. Prod
, vol.67
, pp. 2141-2153
-
-
Butler, M.S.1
-
6
-
-
33646056420
-
Drug discovery from natural sources
-
Chin, Y. W., Balunas, M. J., Chai, H. B., and Kinghorn, A. D. (2006). Drug discovery from natural sources. AAPS J. 8, E239-E253. doi: 10.1007/BF02854894
-
(2006)
AAPS J
, vol.8
, pp. E239-E253
-
-
Chin, Y.W.1
Balunas, M.J.2
Chai, H.B.3
Kinghorn, A.D.4
-
7
-
-
34548279788
-
Molecular understanding and modern application of traditional medicines: triumphs and trials
-
Corson, T. W., and Crews, C. M. (2007). Molecular understanding and modern application of traditional medicines: triumphs and trials. Cell 130, 769-774. doi: 10.1016/j.cell.2007.08.021
-
(2007)
Cell
, vol.130
, pp. 769-774
-
-
Corson, T.W.1
Crews, C.M.2
-
8
-
-
0035728299
-
Natural product drug discovery in the next millennium
-
Cragg, G. M., and Newman, D. J. (2001). Natural product drug discovery in the next millennium. Pharm. Biol. 39(Suppl. 1), 8-17. doi: 10.1076/phbi.39.s1.8.0009
-
(2001)
Pharm. Biol
, vol.39
, pp. 8-17
-
-
Cragg, G.M.1
Newman, D.J.2
-
9
-
-
84872827945
-
The impact of the United Nations convention on biological diversity on natural products research
-
Cragg, G. M., Newman, D. J., and Rosenthal, J. (2012). The impact of the United Nations convention on biological diversity on natural products research. Nat. Prod. Rep. 29, 1407-1423. doi: 10.1039/c2np20091k
-
(2012)
Nat. Prod. Rep
, vol.29
, pp. 1407-1423
-
-
Cragg, G.M.1
Newman, D.J.2
Rosenthal, J.3
-
10
-
-
0031028432
-
Natural products in drug discovery and development
-
Cragg, G. M., Newman, D. J., and Snader, K. M. (1997). Natural products in drug discovery and development. J. Nat. Prod. 60, 52-60. doi: 10.1021/np9604893
-
(1997)
J. Nat. Prod
, vol.60
, pp. 52-60
-
-
Cragg, G.M.1
Newman, D.J.2
Snader, K.M.3
-
11
-
-
84939879331
-
The pharmaceutical industry and natural products: historical status and new trends
-
David, B., Wolfender, J. L., and Dias, D. A. (2014). The pharmaceutical industry and natural products: historical status and new trends. Phytochem. Rev. 14, 299-315. doi: 10.1007/s11101-014-9367-z
-
(2014)
Phytochem. Rev
, vol.14
, pp. 299-315
-
-
David, B.1
Wolfender, J.L.2
Dias, D.A.3
-
12
-
-
33745041210
-
Drug discovery from natural products
-
Gullo, V. P., McAlpine, J., Lam, K. S., Baker, D., and Petersen, F. (2006). Drug discovery from natural products. J. Indust. Microbiol. Biotechnol. 33, 523-531. doi: 10.1007/s10295-006-0107-2
-
(2006)
J. Indust. Microbiol. Biotechnol
, vol.33
, pp. 523-531
-
-
Gullo, V.P.1
McAlpine, J.2
Lam, K.S.3
Baker, D.4
Petersen, F.5
-
13
-
-
52049109838
-
Natural products in drug discovery
-
Harvey, A. L. (2008). Natural products in drug discovery. Drug Discov. Today 13, 894-901. doi: 10.1016/j.drudis.2008.07.004
-
(2008)
Drug Discov. Today
, vol.13
, pp. 894-901
-
-
Harvey, A.L.1
-
14
-
-
84926205808
-
The re-emergence of natural products for drug discovery in the genomics era
-
Harvey, A. L., Edrada-Ebel, R., and Quinn, R. J. (2015). The re-emergence of natural products for drug discovery in the genomics era. Nat. Rev. Drug Discov. 14, 111-129. doi: 10.1038/nrd4510
-
(2015)
Nat. Rev. Drug Discov
, vol.14
, pp. 111-129
-
-
Harvey, A.L.1
Edrada-Ebel, R.2
Quinn, R.J.3
-
15
-
-
84947263592
-
'Ethnopharmacology and drug discovery'
-
eds Reedijk, J. (Waltham, MA: Elsevier)
-
Heinrich, M. (2013). "Ethnopharmacology and drug discovery". in Elsevier Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, eds Reedijk, J. (Waltham, MA: Elsevier), 1-24.
-
(2013)
Elsevier Reference Module in Chemistry, Molecular Sciences and Chemical Engineering
, pp. 1-24
-
-
Heinrich, M.1
-
16
-
-
67349225685
-
Ethnopharmacological field studies: a critical assessment of their conceptual basis and methods
-
Heinrich, M., Edwards, S., Moerman, D. E., and Leonti, M. (2009). Ethnopharmacological field studies: a critical assessment of their conceptual basis and methods. J. Ethnopharmacol. 124, 1-17. doi: 10.1016/j.jep.2009.03.043
-
(2009)
J. Ethnopharmacol
, vol.124
, pp. 1-17
-
-
Heinrich, M.1
Edwards, S.2
Moerman, D.E.3
Leonti, M.4
-
17
-
-
0035042739
-
Ethnopharmacology in drug discovery: an analysis of its role and potential contribution
-
Heinrich, M., and Gibbons, S. (2001). Ethnopharmacology in drug discovery: an analysis of its role and potential contribution. J. Pharm. Pharmacol. 53, 425-432. doi: 10.1211/0022357011775712
-
(2001)
J. Pharm. Pharmacol
, vol.53
, pp. 425-432
-
-
Heinrich, M.1
Gibbons, S.2
-
19
-
-
34249700741
-
Challenges and opportunities in drug discovery from plants
-
Jachak, S. M., and Saklani, A. (2007). Challenges and opportunities in drug discovery from plants. Curr. Sci. 92, 1251.
-
(2007)
Curr. Sci
, vol.92
, pp. 1251
-
-
Jachak, S.M.1
Saklani, A.2
-
20
-
-
84866739808
-
Drug discovery in pharmaceutical industry: productivity challenges and trends
-
Khanna, I. (2012). Drug discovery in pharmaceutical industry: productivity challenges and trends. Drug Discov. Today 17, 1088-1102. doi: 10.1016/j.drudis.2012.05.007
-
(2012)
Drug Discov. Today
, vol.17
, pp. 1088-1102
-
-
Khanna, I.1
-
21
-
-
79953240916
-
Modern natural products drug discovery and its relevance to biodiversity conservation
-
Kingston, D. G. (2010). Modern natural products drug discovery and its relevance to biodiversity conservation. J. Nat. Prod. 74, 496-511. doi: 10.1021/np100550t
-
(2010)
J. Nat. Prod
, vol.74
, pp. 496-511
-
-
Kingston, D.G.1
-
22
-
-
14944383798
-
The evolving role of natural products in drug discovery
-
Koehn, F. E., and Carter, G. T. (2005). The evolving role of natural products in drug discovery. Nat. Rev. Drug Discov. 4, 206-220. doi: 10.1038/nrd1657
-
(2005)
Nat. Rev. Drug Discov
, vol.4
, pp. 206-220
-
-
Koehn, F.E.1
Carter, G.T.2
-
23
-
-
34249811180
-
New aspects of natural products in drug discovery
-
Lam, K. S. (2007). New aspects of natural products in drug discovery. Trends Microbiol. 15, 279-289. doi: 10.1016/j.tim.2007.04.001
-
(2007)
Trends Microbiol
, vol.15
, pp. 279-289
-
-
Lam, K.S.1
-
24
-
-
67650436176
-
Drug discovery and natural products: end of an era or an endless frontier?
-
Li, J. W. H., and Vederas, J. C. (2009). Drug discovery and natural products: end of an era or an endless frontier? Science 325, 161-165. doi: 10.1126/science.1168243
-
(2009)
Science
, vol.325
, pp. 161-165
-
-
Li, J.W.H.1
Vederas, J.C.2
-
25
-
-
79952131874
-
Impact of high-throughput screening in biomedical research
-
Macarron, R., Banks, M. N., Bojanic, D., Burns, D. J., Cirovic, D. A., Garyantes, T., et al. (2011). Impact of high-throughput screening in biomedical research. Nat. Rev. Drug Discov. 10, 188-195. doi: 10.1038/nrd3368
-
(2011)
Nat. Rev. Drug Discov
, vol.10
, pp. 188-195
-
-
Macarron, R.1
Banks, M.N.2
Bojanic, D.3
Burns, D.J.4
Cirovic, D.A.5
Garyantes, T.6
-
26
-
-
34447096207
-
Plant natural products: back to the future or into extinction?
-
McChesney, J. D., Venkataraman, S. K., and Henri, J. T. (2007). Plant natural products: back to the future or into extinction? Phytochemistry 68, 2015-2022. doi: 10.1016/j.phytochem.2007.04.032
-
(2007)
Phytochemistry
, vol.68
, pp. 2015-2022
-
-
McChesney, J.D.1
Venkataraman, S.K.2
Henri, J.T.3
-
27
-
-
38949166332
-
A review of high throughput technology for the screening of natural products
-
Mishra, K. P., Ganju, L., Sairam, M., Banerjee, P. K., and Sawhney, R. C. (2008). A review of high throughput technology for the screening of natural products. Biomed. Pharmacother. 62, 94-98. doi: 10.1016/j.biopha.2007.06.012
-
(2008)
Biomed. Pharmacother
, vol.62
, pp. 94-98
-
-
Mishra, K.P.1
Ganju, L.2
Sairam, M.3
Banerjee, P.K.4
Sawhney, R.C.5
-
28
-
-
77953431723
-
Open innovation: chances and challenges for the pharmaceutical industry
-
Niedergassel, B., and Leker, J. (2009). Open innovation: chances and challenges for the pharmaceutical industry. Future Med. Chem. 1, 1197-1200. doi: 10.4155/fmc.09.107
-
(2009)
Future Med. Chem
, vol.1
, pp. 1197-1200
-
-
Niedergassel, B.1
Leker, J.2
-
29
-
-
2942565810
-
Natural products and combinatorial chemistry: back to the future
-
Ortholand, J. Y., and Ganesan, A. (2004). Natural products and combinatorial chemistry: back to the future. Curr. Opin. Chem. Biol. 8, 271-280. doi: 10.1016/j.cbpa.2004.04.011
-
(2004)
Curr. Opin. Chem. Biol
, vol.8
, pp. 271-280
-
-
Ortholand, J.Y.1
Ganesan, A.2
-
30
-
-
27144547510
-
The renaissance of natural products as drug candidates
-
Paterson, I., and Anderson, E. A. (2005). The renaissance of natural products as drug candidates. Science 310, 451. doi: 10.1126/science.1116364
-
(2005)
Science
, vol.310
, pp. 451
-
-
Paterson, I.1
Anderson, E.A.2
-
31
-
-
43049183607
-
Natural products as a robust source of new drugs and drug leads: past successes and present day issues
-
Rishton, G. M. (2008). Natural products as a robust source of new drugs and drug leads: past successes and present day issues. Am. J. Cardiol. 101, S43-S49. doi: 10.1016/j.amjcard.2008.02.007
-
(2008)
Am. J. Cardiol
, vol.101
, pp. S43-S49
-
-
Rishton, G.M.1
-
32
-
-
12444274300
-
Virtual screening on natural products for discovering active compounds and target information
-
Shen, J., Xu, X., Cheng, F., Liu, H., Luo, X., Shen, J., et al. (2003). Virtual screening on natural products for discovering active compounds and target information. Curr. Med. Chem. 10, 2327-2342. doi: 10.2174/0929867033456729
-
(2003)
Curr. Med. Chem
, vol.10
, pp. 2327-2342
-
-
Shen, J.1
Xu, X.2
Cheng, F.3
Liu, H.4
Luo, X.5
Shen, J.6
-
33
-
-
0031695495
-
Recent natural products based drug development: a pharmaceutical industry perspective
-
Shu, Y. Z. (1998). Recent natural products based drug development: a pharmaceutical industry perspective. J. Nat. Prod. 61, 1053-1071. doi: 10.1021/np9800102
-
(1998)
J. Nat. Prod
, vol.61
, pp. 1053-1071
-
-
Shu, Y.Z.1
-
34
-
-
2342658946
-
The role of weeds as sources of pharmaceuticals
-
Stepp, J. R. (2004). The role of weeds as sources of pharmaceuticals. J. Ethnopharmacol. 92, 163-166. doi: 10.1016/j.jep.2004.03.002
-
(2004)
J. Ethnopharmacol
, vol.92
, pp. 163-166
-
-
Stepp, J.R.1
-
35
-
-
58149141541
-
Drug discovery: new models for industry-academic partnerships
-
Tralau-Stewart, C. J., Wyatt, C. A., Kleyn, D. E., and Ayad, A. (2009). Drug discovery: new models for industry-academic partnerships. Drug Discov. Today 14, 95-101. doi: 10.1016/j.drudis.2008.10.003
-
(2009)
Drug Discov. Today
, vol.14
, pp. 95-101
-
-
Tralau-Stewart, C.J.1
Wyatt, C.A.2
Kleyn, D.E.3
Ayad, A.4
-
36
-
-
2942566175
-
Natural products in the process of finding new drug candidates
-
Vuorelaa, P., Leinonenb, M., Saikkuc, P., Tammelaa, P., Rauhad, J. P., Wennberge, T., et al. (2004). Natural products in the process of finding new drug candidates. Curr. Med. Chem. 11, 1375-1389. doi: 10.2174/0929867043365116
-
(2004)
Curr. Med. Chem
, vol.11
, pp. 1375-1389
-
-
Vuorelaa, P.1
Leinonenb, M.2
Saikkuc, P.3
Tammelaa, P.4
Rauhad, J.P.5
Wennberge, T.6
|