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Volumn 6, Issue OCT, 2015, Pages

Natural products and drug discovery: A survey of stakeholders in industry and academia

Author keywords

Academia industry links; Big Pharma; Drug discovery; HTS; Natural products; Strategy

Indexed keywords

NATURAL PRODUCT;

EID: 84947246252     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2015.00237     Document Type: Article
Times cited : (53)

References (36)
  • 1
    • 84914167700 scopus 로고    scopus 로고
    • Alkaloids as drug leads-A predictive structural and biodiversity-based analysis
    • Amirkia, V., and Heinrich, M. (2014). Alkaloids as drug leads-A predictive structural and biodiversity-based analysis. Phytochem. Lett. 10, xlviii-liii. doi: 10.1016/j.phytol.2014.06.015
    • (2014) Phytochem. Lett , vol.10 , pp. xlviii-liii
    • Amirkia, V.1    Heinrich, M.2
  • 2
    • 36348987143 scopus 로고    scopus 로고
    • The value of natural products to future pharmaceutical discovery
    • Baker, D. D., Chu, M., Oza, U., and Rajgarhia, V. (2007). The value of natural products to future pharmaceutical discovery. Nat. Prod. Rep. 24, 1225-1244. doi: 10.1039/b602241n
    • (2007) Nat. Prod. Rep , vol.24 , pp. 1225-1244
    • Baker, D.D.1    Chu, M.2    Oza, U.3    Rajgarhia, V.4
  • 3
    • 27844474247 scopus 로고    scopus 로고
    • Drug discovery from medicinal plants
    • Balunas, M. J., and Kinghorn, A. D. (2005). Drug discovery from medicinal plants. Life Sci. 78, 431-441. doi: 10.1016/j.lfs.2005.09.012
    • (2005) Life Sci , vol.78 , pp. 431-441
    • Balunas, M.J.1    Kinghorn, A.D.2
  • 5
    • 11344292132 scopus 로고    scopus 로고
    • The role of natural product chemistry in drug discovery
    • Butler, M. S. (2004). The role of natural product chemistry in drug discovery. J. Nat. Prod. 67, 2141-2153. doi: 10.1021/np040106y
    • (2004) J. Nat. Prod , vol.67 , pp. 2141-2153
    • Butler, M.S.1
  • 6
    • 33646056420 scopus 로고    scopus 로고
    • Drug discovery from natural sources
    • Chin, Y. W., Balunas, M. J., Chai, H. B., and Kinghorn, A. D. (2006). Drug discovery from natural sources. AAPS J. 8, E239-E253. doi: 10.1007/BF02854894
    • (2006) AAPS J , vol.8 , pp. E239-E253
    • Chin, Y.W.1    Balunas, M.J.2    Chai, H.B.3    Kinghorn, A.D.4
  • 7
    • 34548279788 scopus 로고    scopus 로고
    • Molecular understanding and modern application of traditional medicines: triumphs and trials
    • Corson, T. W., and Crews, C. M. (2007). Molecular understanding and modern application of traditional medicines: triumphs and trials. Cell 130, 769-774. doi: 10.1016/j.cell.2007.08.021
    • (2007) Cell , vol.130 , pp. 769-774
    • Corson, T.W.1    Crews, C.M.2
  • 8
    • 0035728299 scopus 로고    scopus 로고
    • Natural product drug discovery in the next millennium
    • Cragg, G. M., and Newman, D. J. (2001). Natural product drug discovery in the next millennium. Pharm. Biol. 39(Suppl. 1), 8-17. doi: 10.1076/phbi.39.s1.8.0009
    • (2001) Pharm. Biol , vol.39 , pp. 8-17
    • Cragg, G.M.1    Newman, D.J.2
  • 9
    • 84872827945 scopus 로고    scopus 로고
    • The impact of the United Nations convention on biological diversity on natural products research
    • Cragg, G. M., Newman, D. J., and Rosenthal, J. (2012). The impact of the United Nations convention on biological diversity on natural products research. Nat. Prod. Rep. 29, 1407-1423. doi: 10.1039/c2np20091k
    • (2012) Nat. Prod. Rep , vol.29 , pp. 1407-1423
    • Cragg, G.M.1    Newman, D.J.2    Rosenthal, J.3
  • 10
    • 0031028432 scopus 로고    scopus 로고
    • Natural products in drug discovery and development
    • Cragg, G. M., Newman, D. J., and Snader, K. M. (1997). Natural products in drug discovery and development. J. Nat. Prod. 60, 52-60. doi: 10.1021/np9604893
    • (1997) J. Nat. Prod , vol.60 , pp. 52-60
    • Cragg, G.M.1    Newman, D.J.2    Snader, K.M.3
  • 11
    • 84939879331 scopus 로고    scopus 로고
    • The pharmaceutical industry and natural products: historical status and new trends
    • David, B., Wolfender, J. L., and Dias, D. A. (2014). The pharmaceutical industry and natural products: historical status and new trends. Phytochem. Rev. 14, 299-315. doi: 10.1007/s11101-014-9367-z
    • (2014) Phytochem. Rev , vol.14 , pp. 299-315
    • David, B.1    Wolfender, J.L.2    Dias, D.A.3
  • 13
    • 52049109838 scopus 로고    scopus 로고
    • Natural products in drug discovery
    • Harvey, A. L. (2008). Natural products in drug discovery. Drug Discov. Today 13, 894-901. doi: 10.1016/j.drudis.2008.07.004
    • (2008) Drug Discov. Today , vol.13 , pp. 894-901
    • Harvey, A.L.1
  • 14
    • 84926205808 scopus 로고    scopus 로고
    • The re-emergence of natural products for drug discovery in the genomics era
    • Harvey, A. L., Edrada-Ebel, R., and Quinn, R. J. (2015). The re-emergence of natural products for drug discovery in the genomics era. Nat. Rev. Drug Discov. 14, 111-129. doi: 10.1038/nrd4510
    • (2015) Nat. Rev. Drug Discov , vol.14 , pp. 111-129
    • Harvey, A.L.1    Edrada-Ebel, R.2    Quinn, R.J.3
  • 16
    • 67349225685 scopus 로고    scopus 로고
    • Ethnopharmacological field studies: a critical assessment of their conceptual basis and methods
    • Heinrich, M., Edwards, S., Moerman, D. E., and Leonti, M. (2009). Ethnopharmacological field studies: a critical assessment of their conceptual basis and methods. J. Ethnopharmacol. 124, 1-17. doi: 10.1016/j.jep.2009.03.043
    • (2009) J. Ethnopharmacol , vol.124 , pp. 1-17
    • Heinrich, M.1    Edwards, S.2    Moerman, D.E.3    Leonti, M.4
  • 17
    • 0035042739 scopus 로고    scopus 로고
    • Ethnopharmacology in drug discovery: an analysis of its role and potential contribution
    • Heinrich, M., and Gibbons, S. (2001). Ethnopharmacology in drug discovery: an analysis of its role and potential contribution. J. Pharm. Pharmacol. 53, 425-432. doi: 10.1211/0022357011775712
    • (2001) J. Pharm. Pharmacol , vol.53 , pp. 425-432
    • Heinrich, M.1    Gibbons, S.2
  • 19
    • 34249700741 scopus 로고    scopus 로고
    • Challenges and opportunities in drug discovery from plants
    • Jachak, S. M., and Saklani, A. (2007). Challenges and opportunities in drug discovery from plants. Curr. Sci. 92, 1251.
    • (2007) Curr. Sci , vol.92 , pp. 1251
    • Jachak, S.M.1    Saklani, A.2
  • 20
    • 84866739808 scopus 로고    scopus 로고
    • Drug discovery in pharmaceutical industry: productivity challenges and trends
    • Khanna, I. (2012). Drug discovery in pharmaceutical industry: productivity challenges and trends. Drug Discov. Today 17, 1088-1102. doi: 10.1016/j.drudis.2012.05.007
    • (2012) Drug Discov. Today , vol.17 , pp. 1088-1102
    • Khanna, I.1
  • 21
    • 79953240916 scopus 로고    scopus 로고
    • Modern natural products drug discovery and its relevance to biodiversity conservation
    • Kingston, D. G. (2010). Modern natural products drug discovery and its relevance to biodiversity conservation. J. Nat. Prod. 74, 496-511. doi: 10.1021/np100550t
    • (2010) J. Nat. Prod , vol.74 , pp. 496-511
    • Kingston, D.G.1
  • 22
    • 14944383798 scopus 로고    scopus 로고
    • The evolving role of natural products in drug discovery
    • Koehn, F. E., and Carter, G. T. (2005). The evolving role of natural products in drug discovery. Nat. Rev. Drug Discov. 4, 206-220. doi: 10.1038/nrd1657
    • (2005) Nat. Rev. Drug Discov , vol.4 , pp. 206-220
    • Koehn, F.E.1    Carter, G.T.2
  • 23
    • 34249811180 scopus 로고    scopus 로고
    • New aspects of natural products in drug discovery
    • Lam, K. S. (2007). New aspects of natural products in drug discovery. Trends Microbiol. 15, 279-289. doi: 10.1016/j.tim.2007.04.001
    • (2007) Trends Microbiol , vol.15 , pp. 279-289
    • Lam, K.S.1
  • 24
    • 67650436176 scopus 로고    scopus 로고
    • Drug discovery and natural products: end of an era or an endless frontier?
    • Li, J. W. H., and Vederas, J. C. (2009). Drug discovery and natural products: end of an era or an endless frontier? Science 325, 161-165. doi: 10.1126/science.1168243
    • (2009) Science , vol.325 , pp. 161-165
    • Li, J.W.H.1    Vederas, J.C.2
  • 26
    • 34447096207 scopus 로고    scopus 로고
    • Plant natural products: back to the future or into extinction?
    • McChesney, J. D., Venkataraman, S. K., and Henri, J. T. (2007). Plant natural products: back to the future or into extinction? Phytochemistry 68, 2015-2022. doi: 10.1016/j.phytochem.2007.04.032
    • (2007) Phytochemistry , vol.68 , pp. 2015-2022
    • McChesney, J.D.1    Venkataraman, S.K.2    Henri, J.T.3
  • 27
    • 38949166332 scopus 로고    scopus 로고
    • A review of high throughput technology for the screening of natural products
    • Mishra, K. P., Ganju, L., Sairam, M., Banerjee, P. K., and Sawhney, R. C. (2008). A review of high throughput technology for the screening of natural products. Biomed. Pharmacother. 62, 94-98. doi: 10.1016/j.biopha.2007.06.012
    • (2008) Biomed. Pharmacother , vol.62 , pp. 94-98
    • Mishra, K.P.1    Ganju, L.2    Sairam, M.3    Banerjee, P.K.4    Sawhney, R.C.5
  • 28
    • 77953431723 scopus 로고    scopus 로고
    • Open innovation: chances and challenges for the pharmaceutical industry
    • Niedergassel, B., and Leker, J. (2009). Open innovation: chances and challenges for the pharmaceutical industry. Future Med. Chem. 1, 1197-1200. doi: 10.4155/fmc.09.107
    • (2009) Future Med. Chem , vol.1 , pp. 1197-1200
    • Niedergassel, B.1    Leker, J.2
  • 29
    • 2942565810 scopus 로고    scopus 로고
    • Natural products and combinatorial chemistry: back to the future
    • Ortholand, J. Y., and Ganesan, A. (2004). Natural products and combinatorial chemistry: back to the future. Curr. Opin. Chem. Biol. 8, 271-280. doi: 10.1016/j.cbpa.2004.04.011
    • (2004) Curr. Opin. Chem. Biol , vol.8 , pp. 271-280
    • Ortholand, J.Y.1    Ganesan, A.2
  • 30
    • 27144547510 scopus 로고    scopus 로고
    • The renaissance of natural products as drug candidates
    • Paterson, I., and Anderson, E. A. (2005). The renaissance of natural products as drug candidates. Science 310, 451. doi: 10.1126/science.1116364
    • (2005) Science , vol.310 , pp. 451
    • Paterson, I.1    Anderson, E.A.2
  • 31
    • 43049183607 scopus 로고    scopus 로고
    • Natural products as a robust source of new drugs and drug leads: past successes and present day issues
    • Rishton, G. M. (2008). Natural products as a robust source of new drugs and drug leads: past successes and present day issues. Am. J. Cardiol. 101, S43-S49. doi: 10.1016/j.amjcard.2008.02.007
    • (2008) Am. J. Cardiol , vol.101 , pp. S43-S49
    • Rishton, G.M.1
  • 32
    • 12444274300 scopus 로고    scopus 로고
    • Virtual screening on natural products for discovering active compounds and target information
    • Shen, J., Xu, X., Cheng, F., Liu, H., Luo, X., Shen, J., et al. (2003). Virtual screening on natural products for discovering active compounds and target information. Curr. Med. Chem. 10, 2327-2342. doi: 10.2174/0929867033456729
    • (2003) Curr. Med. Chem , vol.10 , pp. 2327-2342
    • Shen, J.1    Xu, X.2    Cheng, F.3    Liu, H.4    Luo, X.5    Shen, J.6
  • 33
    • 0031695495 scopus 로고    scopus 로고
    • Recent natural products based drug development: a pharmaceutical industry perspective
    • Shu, Y. Z. (1998). Recent natural products based drug development: a pharmaceutical industry perspective. J. Nat. Prod. 61, 1053-1071. doi: 10.1021/np9800102
    • (1998) J. Nat. Prod , vol.61 , pp. 1053-1071
    • Shu, Y.Z.1
  • 34
    • 2342658946 scopus 로고    scopus 로고
    • The role of weeds as sources of pharmaceuticals
    • Stepp, J. R. (2004). The role of weeds as sources of pharmaceuticals. J. Ethnopharmacol. 92, 163-166. doi: 10.1016/j.jep.2004.03.002
    • (2004) J. Ethnopharmacol , vol.92 , pp. 163-166
    • Stepp, J.R.1
  • 35
    • 58149141541 scopus 로고    scopus 로고
    • Drug discovery: new models for industry-academic partnerships
    • Tralau-Stewart, C. J., Wyatt, C. A., Kleyn, D. E., and Ayad, A. (2009). Drug discovery: new models for industry-academic partnerships. Drug Discov. Today 14, 95-101. doi: 10.1016/j.drudis.2008.10.003
    • (2009) Drug Discov. Today , vol.14 , pp. 95-101
    • Tralau-Stewart, C.J.1    Wyatt, C.A.2    Kleyn, D.E.3    Ayad, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.