HPTLC Analysis of Bioactivity Guided Anticancer Enriched Fraction of Hydroalcoholic Extract of Picrorhiza kurroa

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Mallick, Md Nasar ^a   Singh, Mhaveer ^a   Parveen, Rabea ^a   Khan, Washim ^a   Ahmad, Sayeed ^a   Zeeshan Najm, Mohammad ^b   Husain, Syed Akhtar ^a  

^a HAMDARD UNIVERSITY   (India)

^b JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

APOCYNIN; BETULIC ACID; CUCURBITACIN; CUCURBITACIN B; CUCURBITACIN E; CYTOTOXIC AGENT; FLUOROURACIL; PICRORHIZA KURROA EXTRACT; PICROSIDE I; PICROSIDE II; PLANT GLYCOSIDE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; PLANT EXTRACT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER REGRESSION; CANCER SIZE; CELL VACUOLE; CELL VIABILITY; CONTROLLED STUDY; DERIVATIZATION; DRUG CYTOTOXICITY; FEMALE; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC50; IN VIVO STUDY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MOUSE; NONHUMAN; TREATMENT DURATION; UTERINE CERVIX CANCER; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; DIET THERAPY; EHRLICH ASCITES TUMOR; HELA CELL LINE; MCF-7 CELL LINE; PHYTOTHERAPY; PICRORHIZA KURROA; PROCEDURES; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARCINOMA, EHRLICH TUMOR; CELL LINE, TUMOR; FEMALE; HELA CELLS; HUMANS; MCF-7 CELLS; MICE; MICE, INBRED BALB C; PHYTOTHERAPY; PICRORHIZA; PLANT EXTRACTS;

EID: 84947236745     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/513875     Document Type: Article

References (43)

1. R. L. Siegel, K. D. Miller, and A. Jemal"Cancer statistics"CA: A Cancer Journal for Clinicians, vol. 65, no. 1, pp. 5-29, 2015.
2. Z. Wang"Roles of K+ channels in regulating tumour cell proliferation and apoptosis"Pflugers Archiv: European Journal of Physiology, vol. 448, no. 3, pp. 274-286, 2004.
3. R. Gerl and D. L. Vaux"Apoptosis in the development and treatment of cancer"Carcinogenesis, vol. 26, no. 2, pp. 263-270, 2005.
4. T. M. Beer and J. S. Bubalo"Complications of chemotherapy for prostate cancer"Seminars in Urologic Oncology, vol. 19, no. 3, pp. 222-230, 2001.
5. R. C. F. Leonard, S. Williams, A. Tulpule, A. M. Levine, and S. Oliveros"Improving the therapeutic index of anthracycline chemotherapy: focus on liposomal doxorubicin (Myocet)"Breast, vol. 18, no. 4, pp. 218-224, 2009.
6. C. W. Benjamin, R. R. Hiebsch, and D. A. Jones"Caspase activation in MCF7 cells responding to etoposide treatment"Molecular Pharmacology, vol. 53, no. 3, pp. 446-450, 1998.
7. J. Zargan, M. Sajad, S. Umar, M. Naime, S. Ali, and H. A. Khan"Scorpion (Androctonus crassicauda) venom limits growth of transformed cells (SH-SY5Y and MCF-7) by cytotoxicity and cell cycle arrest"Experimental andMolecular Pathology, vol. 91, no. 1, pp. 447-454, 2011.
8. B. Patwardhan and M. Gautam"Botanical immunodrugs: scope and opportunities"Drug Discovery Today, vol. 10, no. 7, pp. 495-502, 2005.
9. T. Sidiq, A. Khajuria, P. Suden et al."Possible role of macrophages induced by an irridoid glycoside (RLJ-NE-299A) in host defense mechanism"International Immunopharmacology, vol. 11, no. 1, pp. 128-135, 2011.
10. O. Kayser, K. N. Masihi, and A. F. Kiderlen"Natural products and synthetic compounds as immunomodulators"Expert Review of Anti-Infective Therapy, vol. 1, no. 2, pp. 319-335, 2003.
11. P. Anand, A. B. Kunnumakkara, K. B. Harikumar, K. S. Ahn, V. Badmaev, and B. B. Aggarwal"Modification of cysteine residue in p65 subunit of nuclear factor-B (NF-B) by picroliv suppresses NF-B-regulated gene products and potentiates apoptosis"Cancer Research, vol. 68, no. 21, pp. 8861-8870, 2008.
12. V. Rajkumar, G. Guha, and R. A. Kumar"Antioxidant and antineoplastic activities of Picrorhiza kurroa extracts"Food and Chemical Toxicology, vol. 49, no. 2, pp. 363-369, 2011.
13. A. Russo, A. A. Izzo, V. Cardile, F. Borrelli, and A. Vanella"Indian medicinal plants as antiradicals and DNA cleavage protectors"Phytomedicine, vol. 8, no. 2, pp. 125-132, 2001.
14. A. Ray, S. R. Chaudhuri, B. Majumdar, and S. K. Bandyopadhyay"Antioxidant activity of ethanol extract of rhizome of Picrorhiza kurroa on indomethacin induced gastric ulcer during healing"Indian Journal of Clinical Biochemistry, vol. 17, no. 2, pp. 44-51, 2002.
15. A. A. Patil, B. S. Sachin, D. B. Shinde, and P. S. Wakte"SupercriticalCO2 assisted extraction and LC-MS identification of picroside i and picroside II from Picrorhiza kurroa"Phytochemical Analysis, vol. 24, no. 2, pp. 97-104, 2013.
16. S. S. Tiwari, M. M. Pandey, S. Srivastava, and A. Rawat"TLC densitometric quantification of picrosides (picroside-I and picroside-II) in Picrorhiza kurroa and its substitute Picrorhiza scrophulariiflora and their antioxidant studies"Biomedical Chromatography, vol. 26, no. 1, pp. 61-68, 2012.
17. T. Kawoosa, H. Singh, A. Kumar et al."Light and temperature regulated terpene biosynthesis: hepatoprotective monoterpene picroside accumulation in Picrorhiza kurrooa"Functional &Integrative Genomics, vol. 10, no. 3, pp. 393-404, 2010.
18. H. Stuppner and H. Wagner"New cucurbitacin glycosides fom Picrorhiza kurrooa"Planta Medica, vol. 55, no. 6, pp. 559-563, 1989.
19. S. Sturm and H. Stuppner"Analysis of cucurbitacins in medicinal plants by high-pressure liquid chromatography-mass spectrometry"Phytochemical Analysis, vol. 11, no. 2, pp. 121-127, 2000.
20. N. Sindhu, T. Pratima, andW. Ashwini"Isolation of a cucurbitacin from Picrorhiza Kurroa by column chromatography and its characterization"Research Journal of Pharmaceutical, Biological and Chemical Sciences, vol. 2, no. 3, pp. 149-156, 2011.
21. F. Engels, B. F. Renirie, B. A. Hart, R. P. Labadie, and F. P. Nijkamp"Effects of apocynin, a drug isolated from the roots of Picrorhiza kurroa, on arachidonic acid metabolism"FEBS Letters, vol. 305, no. 3, pp. 254-256, 1992.
22. Y. Kong, J. Chen, Z. Zhou, H. Xia, M.-H. Qiu, and C. Chen"Cucurbitacin e induces cell cycle G2/M phase arrest and apoptosis in triple negative breast cancer"PLoS ONE, vol. 9, no. 7, Article ID e103760, 2014.
23. A. A. Alghasham"Cucurbitacins-A promising target for cancer therapy"International Journal of Health Sciences, vol. 7, no. 1, pp. 77-89, 2013.
24. A. Aribi, S. Gery, D.H. Lee et al."The triterpenoid cucurbitacin B augments the antiproliferative activity of chemotherapy in human breast cancer"International Journal of Cancer, vol. 132, no. 12, pp. 2730-2737, 2013.
25. S. Duangmano, P. Sae-Lim, A. Suksamrarn, F. E. Domann, and P. Patmasiriwat"Cucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation"BMC Complementary Alternative Medicine, vol. 12, article 185, 12 pages, 2012.
26. J.-S. Zhu, D.-Y. Ouyang, Z.-J. Shi, L.-H. Xu, Y.-T. Zhang, and X.-H. He"Cucurbitacin B induces cell cycle arrest, apoptosis and autophagy associated with G actin reduction and persistent activation of cofilin in Jurkat cells"Pharmacology, vol. 89, no. 5-6, pp. 348-356, 2012.
27. J.-J. Li, Y.-T. Zhang, D.-Y. Ouyang, L.-H. Xu, H.-B. Mo, and X.-H. He"Suppression of STAT3 phosphorylation enhances the cytotoxicity of cucurbitacin B in B16F10 melanoma cells"African Journal of Pharmacy and Pharmacology, vol. 6, no. 21, pp. 1545-1554, 2012.
28. C. Boykin, G. Zhang, Y.-H. Chen et al."Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation"British Journal of Cancer, vol. 104, no. 5, pp. 781-789, 2011.
29. K. T. Chan, F. Y. Meng, Q. Li et al."Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration"Cancer Letters, vol. 294, no. 1, pp. 118-124, 2010.
30. A. C. de Almeida, O. C. Marques, C. Arslanian, A. Condino-Neto, and V. F. Ximenes"4-Fluoro-2-methoxyphenol, an apocynin analog with enhanced inhibitory effect on leukocyte oxidant production and phagocytosis"European Journal of Pharmacology, vol. 660, no. 2-3, pp. 445-453, 2011.
31. C. J. Henrich, C. L. Thomas, A.D. Brooks et al."Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis"Apoptosis, vol. 17, no. 1, pp. 79-89, 2012.
32. S. Yasuda, S. Yogosawa, Y. Izutani, Y. Nakamura, H. Watanabe, and T. Sakai"Cucurbitacin B induces G2 arrest and apoptosis via a reactive oxygen species-dependent mechanism in human colon adenocarcinoma SW480 cells"Molecular Nutrition &Food Research, vol. 54, no. 4, pp. 559-565, 2010.
33. Y. Dong, B. Lu, X. Zhang et al."Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis throughVEGFR2-mediated Jak2-STAT3 signaling pathway"Carcinogenesis, vol. 31, no. 12, pp. 2097-2104, 2010.
34. D. Rathee, M. Thanki, S. Bhuva, S. Anandjiwala, and R. Agrawal"Iridoid glycosides-Kutkin, Picroside I, and Kutkoside from Picrorrhiza kurroa Benth inhibits the invasion and migration of MCF-7 breast cancer cells through the down regulation of matrix metalloproteinases"Arabian Journal of Chemistry, vol. 6, no. 1, pp. 49-58, 2013.
35. R. Parveen, F. J. Ahmad, Z. Iqbal, M. Singh, Y. T. Kamal, and S. Ahmad"Simultaneous estimation of anti-cancer terpenoids in pharmaceutical nanoformulation by RP-HPLC and HPTLC"Acta Chromatographica, vol. 26, no. 2, pp. 391-400, 2014.
36. Y. T. Kamal, S. M. Musthaba, M. Singh et al."Development and validation of HPLCmethod for simultaneous estimation of piperine and guggulsterones in compound Unani formulation (tablets) and a nanoreservoir system"Biomedical Chromatography, vol. 26, no. 10, pp. 1183-1190, 2012.
37. Pharmacopoeia of India, Ministry of Health, Government of India, 2nd edition, 1966.
38. R. Asirvatham and A. J. M. Christina"Anticancer activity of Drosera indica L., on Dalton's Lymphoma Ascites (DLA) bearing mice"Journal of Intercultural Ethnopharmacology, vol. 2, no. 1, pp. 9-14, 2013.
39. R. Parveen, F. J. Ahmad, Z. Iqbal, M. Samim, and S. Ahmad"Solid lipid nanoparticles of anticancer drug andrographolide: formulation, in vitro and in vivo studies"Drug Development and Industrial Pharmacy, vol. 40, no. 9, pp. 1206-1212, 2014.
40. M. I. Sriram, S. B. M. Kanth, K. Kalishwaralal, and S. Gurunathan"Antitumor activity of silver nanoparticles in Dalton's lymphoma ascites tumor model"International Journal of Nanomedicine, vol. 5, no. 1, pp. 753-762, 2010.
41. V. Zuco, R. Supino, S. C. Righetti et al."Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells"Cancer Letters, vol. 175, no. 1, pp. 17-25, 2002.
42. Y. T. Ho, C. C. Lu, J. S. Yang et al."Berberine induced apoptosis via promoting the expression of caspase-8, 9 and 3, apoptosisinducing factor and endonuclease G in SCC-4 human tongue squamous carcinoma cancer cells"Anticancer Research, vol. 29, no. 10, pp. 4063-4070, 2009.
43. N. Armania, L. S. Yazan, S. N. Musa et al."Dillenia suffruticosa exhibited antioxidant and cytotoxic activity through induction of apoptosis and G2/M cell cycle arrest"Journal of Ethnopharmacology, vol. 146, no. 2, pp. 525-535, 2013.