Identification of the Protective Role of DJ-1 in Hypoglycemic Astrocyte Injury Using Proteomics

Journal of Proteome Research

Volumn 14, Issue 7, 2015, Pages 2839-2848

  Deng, Jiangshan ^a   Zhao, Fei ^a   Yu, Xiaoyan ^a   Li, Dawei ^b   Zhao, Yuwu ^a  

^a SHANGHAI JIAO TONG UNIVERSITY AFFILIATED SIXTH PEOPLE S HOSPITAL   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

autophagy; brain injury; DJ 1; hypoglycemia; iTRAQ

Indexed keywords

DJ 1 PROTEIN; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MICROTUBULE ASSOCIATED PROTEIN; SP22 PROTEIN, RAT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; AUTOPHAGY; BRAIN INJURY; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; GENE SILENCING; HIGH THROUGHPUT SCREENING; HYPOGLYCEMIA; IN VITRO STUDY; ISOBARIC TAG FOR RELATIVE AND ABSOLUTE QUANTITATION; LIQUID CHROMATOGRAPHY; MALE; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; TANDEM MASS SPECTROMETRY; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL LINE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ASTROCYTES; CELL LINE; HYPOGLYCEMIA; MALE; MICROTUBULE-ASSOCIATED PROTEINS; PROTEOMICS; RATS, SPRAGUE-DAWLEY;

EID: 84947232571     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/acs.jproteome.5b00514     Document Type: Article

References (30)

1. Cryer, P. E. The barrier of hypoglycemia in diabetes Diabetes 2008, 57 (12) 3169-3176
2. Suh, S. W.; Hamby, A. M.; Swanson, R. A. Hypoglycemia, brain energetics, and hypoglycemic neuronal death Glia 2007, 55 (12) 1280-1286
3. Suh, S. W.; Gum, E. T.; Hamby, A. M.; Chan, P. H.; Swanson, R. A. Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase J. Clin Invest. 2007, 117 (4) 910-918
4. Swanson, R. A.; Suh, S. W., Hypoglycemic Neuronal Death. In Acute Neuronal Injury; Springer: New York, 2010; pp 211-228.
5. Ralhan, R.; DeSouza, L. V.; Matta, A.; Tripathi, S. C.; Ghanny, S.; Gupta, S. D.; Bahadur, S.; Siu, K. M. Discovery and verification of head-and-neck cancer biomarkers by differential protein expression analysis using iTRAQ labeling, multidimensional liquid chromatography, and tandem mass spectrometry Mol. Cell. Proteomics 2008, 7 (6) 1162-1173
6. Deng, J.; Zhao, F.; Yu, X.; Zhao, Y.; Li, D.; Shi, H.; Sun, Y. Expression of Aquaporin 4 and Breakdown of the Blood-Brain Barrier after Hypoglycemia-Induced Brain Edema in Rats PLoS One 2014, 9 (9) e107022
7. Unwin, R. D.; Griffiths, J. R.; Whetton, A. D. Simultaneous analysis of relative protein expression levels across multiple samples using iTRAQ isobaric tags with 2D nano LC-MS/MS Nat. Protoc. 2010, 5 (9) 1574-1582
8. Bandopadhyay, R.; Kingsbury, A. E.; Cookson, M. R.; Reid, A. R.; Evans, I. M.; Hope, A. D.; Pittman, A. M.; Lashley, T.; Canet-Aviles, R.; Miller, D. W. The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinsons disease Brain 2004, 127 (2) 420-430
9. Mullett, S. J.; Hamilton, R. L.; Hinkle, D. A. DJ-1 immunoreactivity in human brain astrocytes is dependent on infarct presence and infarct age Neuropathology 2009, 29 (2) 125-131
10. Brown, A. M.; Ransom, B. R. Astrocyte glycogen and brain energy metabolism Glia 2007, 55 (12) 1263-1271
11. Yanagida, T.; Tsushima, J.; Kitamura, Y.; Yanagisawa, D.; Takata, K.; Shibaike, T.; Yamamoto, A.; Taniguchi, T.; Yasui, H.; Taira, T. Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury Oxid Med. Cell. Longevity 2009, 2 (1) 36-42
12. Vasseur, S.; Afzal, S.; Tardivel-Lacombe, J.; Park, D. S.; Iovanna, J. L.; Mak, T. W. DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses Proc. Natl. Acad. Sci. U.S.A. 2009, 106 (4) 1111-1116
13. Zondler, L.; Miller-Fleming, L.; Repici, M.; Goncalves, S.; Tenreiro, S.; Rosado-Ramos, R.; Betzer, C.; Straatman, K. R.; Jensen, P. H.; Giorgini, F.; Outeiro, T. F. DJ-1 interactions with alpha-synuclein attenuate aggregation and cellular toxicity in models of Parkinsons disease Cell Death Dis. 2014, 5, e1350
14. Parsanejad, M.; Bourquard, N.; Qu, D.; Zhang, Y.; Huang, E.; Rousseaux, M. W.; Aleyasin, H.; Irrcher, I.; Callaghan, S.; Vaillant, D. C.; Kim, R. H.; Slack, R. S.; Mak, T. W.; Reddy, S. T.; Figeys, D.; Park, D. S. DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress PLoS One 2014, 9 (9) e106601
15. Kato, I.; Maita, H.; Takahashi-Niki, K.; Saito, Y.; Noguchi, N.; Iguchi-Ariga, S. M.; Ariga, H. Oxidized DJ-1 inhibits p53 by sequestering p53 from promoters in a DNA-binding affinity-dependent manner Mol. Cell. Biol. 2013, 33 (2) 340-359
16. Steiner, J.; Bernstein, H.-G.; Bogerts, B.; Gos, T.; Richter-Landsberg, C.; Wunderlich, M.; Keilhoff, G. S100B is expressed in, and released from, OLN-93 oligodendrocytes: influence of serum and glucose deprivation Neuroscience 2008, 154 (2) 496-503
17. Ariga, H.; Takahashi-Niki, K.; Kato, I.; Maita, H.; Niki, T.; Iguchi-Ariga, S. M. Neuroprotective function of DJ-1 in Parkinsons disease Oxid. Med. Cell. Longevity 2013, 2013, 683920
18. Kahle, P. J.; Waak, J.; Gasser, T. DJ-1 and prevention of oxidative stress in Parkinsons disease and other age-related disorders Free Radical Biol. Med. 2009, 47 (10) 1354-1361
19. Mullett, S. J.; Hinkle, D. A. DJ-1 knock-down in astrocytes impairs astrocyte-mediated neuroprotection against rotenone Neurobiol. Dis. 2009, 33 (1) 28-36
20. Mullett, S. J.; Di Maio, R.; Greenamyre, J. T.; Hinkle, D. A. DJ-1 expression modulates astrocyte-mediated protection against neuronal oxidative stress J. Mol. Neurosci. 2013, 49 (3) 507-511
21. Klionsky, D. J.; Abdalla, F. C.; Abeliovich, H.; Abraham, R. T.; Acevedo-Arozena, A.; Adeli, K.; Agholme, L.; Agnello, M.; Agostinis, P.; Aguirre-Ghiso, J. A. Guidelines for the use and interpretation of assays for monitoring autophagy Autophagy 2012, 8 (4) 445-544
22. Balmer, D.; Emery, M.; Andreux, P.; Auwerx, J.; Ginet, V.; Puyal, J.; Schorderet, D. F.; Roduit, R. Autophagy Defect Is Associated with Low Glucose-Induced Apoptosis in 661W Photoreceptor Cells PLoS One 2013, 8 (9) e74162
23. Jang, B. G.; Choi, B. Y.; Kim, J. H.; Kim, M.-J.; Sohn, M.; Suh, S. W. Impairment of autophagic flux promotes glucose reperfusion-induced neuro2a cell death after glucose deprivation PLoS One 2013, 8 (10) e76466
24. Marambio, P.; Toro, B.; Sanhueza, C.; Troncoso, R.; Parra, V.; Verdejo, H.; García, L.; Quiroga, C.; Munafo, D.; Díaz-Elizondo, J. Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes Biochim. Biophys. Acta, Mol. Basis Dis. 2010, 1802 (6) 509-518
25. Jänen, S. B.; Chaachouay, H.; Richter-Landsberg, C. Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes Glia 2010, 58 (14) 1766-1774
26. Gabryel, B.; Kost, A.; Kasprowska, D.; Liber, S.; Machnik, G.; Wiaderkiewicz, R.; Łabuzek, K. AMP-activated protein kinase is involved in induction of protective autophagy in astrocytes exposed to oxygen-glucose deprivation Cell Biol. Int. 2014, 38, 1086-1097
27. Kim, J.; Kundu, M.; Viollet, B.; Guan, K.-L. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 Nat. Cell Biol. 2011, 13 (2) 132-141
28. Gao, M.; Liang, J.; Lu, Y.; Guo, H.; German, P.; Bai, S.; Jonasch, E.; Yang, X.; Mills, G. B.; Ding, Z. Site-specific activation of AKT protects cells from death induced by glucose deprivation Oncogene 2013, 33 (6) 745-755
29. Owada, S.; Shimoda, Y.; Tsuchihara, K.; Esumi, H. Glucose deprivation-induced intracellular reactive oxygen species activates the PI3K-AKT axis Cancer Res. 2012, 72 (8 Supplement) 1133-1133
30. Hinkle, D. A.; Mullett, S. J.; Gabris, B. E.; Hamilton, R. L. DJ-1 expression in glioblastomas shows positive correlation with p53 expression and negative correlation with epidermal growth factor receptor amplification Neuropathology 2011, 31 (1) 29-37