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Volumn 10, Issue 10, 2015, Pages

Trypanosoma cruzi and its soluble antigens induce NET release by stimulating toll-like receptors

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ELASTASE; HISTONE; PARASITE ANTIGEN; REACTIVE OXYGEN METABOLITE; RECEPTOR ANTIBODY; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRYPANOSOMA CRUZI ANTIGEN; UNCLASSIFIED DRUG; ANTIGEN; PANCREATIC ELASTASE; TOLL LIKE RECEPTOR;

EID: 84947220736     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0139569     Document Type: Article
Times cited : (59)

References (41)
  • 1
    • 1542287347 scopus 로고    scopus 로고
    • Neutrophil extracellular traps kill bacteria
    • 15001782 New York, NY
    • Brinkmann V, Reichard U, Goosmann C, Fauler B, Uhlemann Y, Weiss DS, et al. Neutrophil extracellular traps kill bacteria. Science (New York, NY. 2004; 303(5663):1532-5. PMID: 15001782.
    • (2004) Science , vol.303 , Issue.5663 , pp. 1532-1535
    • Brinkmann, V.1    Reichard, U.2    Goosmann, C.3    Fauler, B.4    Uhlemann, Y.5    Weiss, D.S.6
  • 2
    • 84906791023 scopus 로고    scopus 로고
    • The intriguing host innate immune response: Novel anti-parasitic defence by neutrophil extracellular traps
    • 24721985
    • Hermosilla C, Caro TM, Silva LM, Ruiz A, Taubert A. The intriguing host innate immune response: novel anti-parasitic defence by neutrophil extracellular traps. Parasitology. 2014:1-10. doi: 10.1017/S0031182014000316 PMID: 24721985.
    • (2014) Parasitology , pp. 1-10
    • Hermosilla, C.1    Caro, T.M.2    Silva, L.M.3    Ruiz, A.4    Taubert, A.5
  • 5
    • 84884679672 scopus 로고    scopus 로고
    • Vibrio cholerae evades neutrophil extracellular traps by the activity of two extracellular nucleases
    • 24039581 PubMed Central PMCID: PMC3764145
    • Seper A, Hosseinzadeh A, Gorkiewicz G, Lichtenegger S, Roier S, Leitner DR, et al. Vibrio cholerae evades neutrophil extracellular traps by the activity of two extracellular nucleases. PLoS pathogens. 2013; 9(9):e1003614. doi: 10.1371/journal.ppat.1003614 PMID: 24039581; PubMed Central PMCID: PMC3764145.
    • (2013) PLoS Pathogens , vol.9 , Issue.9 , pp. e1003614
    • Seper, A.1    Hosseinzadeh, A.2    Gorkiewicz, G.3    Lichtenegger, S.4    Roier, S.5    Leitner, D.R.6
  • 6
    • 84865645565 scopus 로고    scopus 로고
    • Chagas disease in non-endemic countries: Epidemiology, clinical presentation and treatment
    • 22477037
    • Perez-Molina JA, Norman F, Lopez-Velez R. Chagas disease in non-endemic countries: epidemiology, clinical presentation and treatment. Current infectious disease reports. 2012; 14(3):263-74. doi: 10.1007/s11908-012-0259-3 PMID: 22477037.
    • (2012) Current Infectious Disease Reports , vol.14 , Issue.3 , pp. 263-274
    • Perez-Molina, J.A.1    Norman, F.2    Lopez-Velez, R.3
  • 7
    • 77953028103 scopus 로고    scopus 로고
    • Chagas disease: A Latin American health problem becoming a world health problem
    • 19932071
    • Schmunis GA, Yadon ZE. Chagas disease: a Latin American health problem becoming a world health problem. Acta tropica. 2010; 115(1-2):14-21. doi: 10.1016/j.actatropica.2009.11.003 PMID: 19932071.
    • (2010) Acta Tropica , vol.115 , Issue.1-2 , pp. 14-21
    • Schmunis, G.A.1    Yadon, Z.E.2
  • 8
    • 0021360717 scopus 로고
    • Host cell invasion by trypanosoma cruzi: Role of cell surface galactose residues
    • 6322778
    • Villalta F, Kierszenbaum F. Host cell invasion by Trypanosoma cruzi: role of cell surface galactose residues. Biochemical and biophysical research communications. 1984; 119(1):228-35. PMID: 6322778.
    • (1984) Biochemical and Biophysical Research Communications , vol.119 , Issue.1 , pp. 228-235
    • Villalta, F.1    Kierszenbaum, F.2
  • 9
    • 0034793409 scopus 로고    scopus 로고
    • Proinflammatory activity of glycosylphosphatidylinositol anchors derived from trypanosoma cruzi: Structural and functional analyses
    • 11590183
    • Almeida IC, Gazzinelli RT. Proinflammatory activity of glycosylphosphatidylinositol anchors derived from Trypanosoma cruzi: structural and functional analyses. Journal of leukocyte biology. 2001; 70 (4):467-77. PMID: 11590183.
    • (2001) Journal of Leukocyte Biology , vol.70 , Issue.4 , pp. 467-477
    • Almeida, I.C.1    Gazzinelli, R.T.2
  • 10
    • 77953024151 scopus 로고    scopus 로고
    • The innate immune response to trypanosoma cruzi infection. Microbes and infection
    • 20348008
    • Kayama H, Takeda K. The innate immune response to Trypanosoma cruzi infection. Microbes and infection/Institut Pasteur. 12(7):511-7. PMID: 20348008. doi: 10.1016/j.micinf.2010.03.005
    • Institut Pasteur , vol.12 , Issue.7 , pp. 511-517
    • Kayama, H.1    Takeda, K.2
  • 11
    • 73949085808 scopus 로고    scopus 로고
    • Fetal calf serum contains heat-stable nucleases that degrade neutrophil extracellular traps
    • 20007813 PubMed Central PMCID: PMC2792215
    • von Kockritz-Blickwede M, Chow OA, Nizet V. Fetal calf serum contains heat-stable nucleases that degrade neutrophil extracellular traps. Blood. 2009; 114(25):5245-6. doi: 10.1182/blood-2009-08-240713 PMID: 20007813; PubMed Central PMCID: PMC2792215.
    • (2009) Blood , vol.114 , Issue.25 , pp. 5245-5246
    • Von Kockritz-Blickwede, M.1    Chow, O.A.2    Nizet, V.3
  • 12
    • 79251606968 scopus 로고    scopus 로고
    • Heat-killed trypanosoma cruzi induces acute cardiac damage and polyantigenic autoimmunity
    • 21283741 PubMed Central PMCID: PMC3024973
    • Bonney KM, Taylor JM, Daniels MD, Epting CL, Engman DM. Heat-killed Trypanosoma cruzi induces acute cardiac damage and polyantigenic autoimmunity. PloS one. 2011; 6(1):e14571. doi: 10.1371/journal.pone.0014571 PMID: 21283741; PubMed Central PMCID: PMC3024973.
    • (2011) PloS One , vol.6 , Issue.1 , pp. e14571
    • Bonney, K.M.1    Taylor, J.M.2    Daniels, M.D.3    Epting, C.L.4    Engman, D.M.5
  • 13
    • 0019972544 scopus 로고
    • Resistance against trypanosoma cruzi associated to anti-living trypomastigote antibodies
    • 6801127
    • Krettli AU, Brener Z. Resistance against Trypanosoma cruzi associated to anti-living trypomastigote antibodies. J Immunol. 1982; 128(5):2009-12. PMID: 6801127.
    • (1982) J Immunol. , vol.128 , Issue.5 , pp. 2009-2012
    • Krettli, A.U.1    Brener, Z.2
  • 15
    • 0021334108 scopus 로고
    • Lysosomal enzyme release from polymorphonuclear leukocytes induced by immune complexes of IgM and of IgG
    • 6699405
    • Lucisano YM, Mantovani B. Lysosomal enzyme release from polymorphonuclear leukocytes induced by immune complexes of IgM and of IgG. J Immunol. 1984; 132(4):2015-20. PMID: 6699405.
    • (1984) J Immunol. , vol.132 , Issue.4 , pp. 2015-2020
    • Lucisano, Y.M.1    Mantovani, B.2
  • 16
    • 70350004580 scopus 로고    scopus 로고
    • Restoration of NET formation by gene therapy in CGD controls aspergillosis
    • 19541821 PubMed Central PMCID: PMC2756123
    • Bianchi M, Hakkim A, Brinkmann V, Siler U, Seger RA, Zychlinsky A, et al. Restoration of NET formation by gene therapy in CGD controls aspergillosis. Blood. 2009; 114(13):2619-22. doi: 10.1182/blood-2009-05-221606 PMID: 19541821; PubMed Central PMCID: PMC2756123.
    • (2009) Blood , vol.114 , Issue.13 , pp. 2619-2622
    • Bianchi, M.1    Hakkim, A.2    Brinkmann, V.3    Siler, U.4    Seger, R.A.5    Zychlinsky, A.6
  • 17
    • 84866360345 scopus 로고    scopus 로고
    • Neutrophil extracellular traps: Is immunity the second function of chromatin?
    • 22945932 PubMed Central PMCID: PMC3432757
    • Brinkmann V, Zychlinsky A. Neutrophil extracellular traps: is immunity the second function of chromatin? The Journal of cell biology. 2012; 198(5):773-83. doi: 10.1083/jcb.201203170 PMID: 22945932; PubMed Central PMCID: PMC3432757.
    • (2012) The Journal of Cell Biology , vol.198 , Issue.5 , pp. 773-783
    • Brinkmann, V.1    Zychlinsky, A.2
  • 18
    • 84883814815 scopus 로고    scopus 로고
    • An improved strategy to recover large fragments of functional human neutrophil extracellular traps
    • 23805143 PubMed Central PMCID: PMC3690357
    • Barrientos L, Marin-Esteban V, de Chaisemartin L, Le-Moal VL, Sandre C, Bianchini E, et al. An improved strategy to recover large fragments of functional human neutrophil extracellular traps. Frontiers in immunology. 2013; 4:166. doi: 10.3389/fimmu.2013.00166 PMID: 23805143; PubMed Central PMCID: PMC3690357.
    • (2013) Frontiers in Immunology , vol.4 , pp. 166
    • Barrientos, L.1    Marin-Esteban, V.2    De Chaisemartin, L.3    Le-Moal, V.L.4    Sandre, C.5    Bianchini, E.6
  • 20
    • 84922998533 scopus 로고    scopus 로고
    • Capsular polysaccharides from cryptococcus neoformans modulate production of neutrophil extracellular traps (NETs) by human neutrophils
    • 25620354 PubMed Central PMCID: PMC4306120
    • Rocha JD, Nascimento MT, Decote-Ricardo D, Corte-Real S, Morrot A, Heise N, et al. Capsular polysaccharides from Cryptococcus neoformans modulate production of neutrophil extracellular traps (NETs) by human neutrophils. Scientific reports. 2015; 5:8008. doi: 10.1038/srep08008 PMID: 25620354; PubMed Central PMCID: PMC4306120.
    • (2015) Scientific Reports , vol.5 , pp. 8008
    • Rocha, J.D.1    Nascimento, M.T.2    Decote-Ricardo, D.3    Corte-Real, S.4    Morrot, A.5    Heise, N.6
  • 21
    • 84861034431 scopus 로고    scopus 로고
    • The impact of various reactive oxygen species on the formation of neutrophil extracellular traps
    • 22481865 PubMed Central PMCID: PMC3317033
    • Kirchner T, Moller S, Klinger M, Solbach W, Laskay T, Behnen M. The impact of various reactive oxygen species on the formation of neutrophil extracellular traps. Mediators of inflammation. 2012; 2012:849136. doi: 10.1155/2012/849136 PMID: 22481865; PubMed Central PMCID: PMC3317033.
    • (2012) Mediators of Inflammation , vol.2012 , pp. 849136
    • Kirchner, T.1    Moller, S.2    Klinger, M.3    Solbach, W.4    Laskay, T.5    Behnen, M.6
  • 22
    • 33846432787 scopus 로고    scopus 로고
    • Novel cell death program leads to neutrophil extracellular traps
    • 17210947 PubMed Central PMCID: PMC2063942
    • Fuchs TA, Abed U, Goosmann C, Hurwitz R, Schulze I, Wahn V, et al. Novel cell death program leads to neutrophil extracellular traps. The Journal of cell biology. 2007; 176(2):231-41. doi: 10.1083/jcb. 200606027 PMID: 17210947; PubMed Central PMCID: PMC2063942.
    • (2007) The Journal of Cell Biology , vol.176 , Issue.2 , pp. 231-241
    • Fuchs, T.A.1    Abed, U.2    Goosmann, C.3    Hurwitz, R.4    Schulze, I.5    Wahn, V.6
  • 23
    • 78751693139 scopus 로고    scopus 로고
    • Myeloperoxidase is required for neutrophil extracellular trap formation: Implications for innate immunity
    • 20974672 PubMed Central PMCID: PMC3035083
    • Metzler KD, Fuchs TA, Nauseef WM, Reumaux D, Roesler J, Schulze I, et al. Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity. Blood. 2011; 117 (3):953-9. doi: 10.1182/blood-2010-06-290171 PMID: 20974672; PubMed Central PMCID: PMC3035083.
    • (2011) Blood , vol.117 , Issue.3 , pp. 953-959
    • Metzler, K.D.1    Fuchs, T.A.2    Nauseef, W.M.3    Reumaux, D.4    Roesler, J.5    Schulze, I.6
  • 24
    • 32944463724 scopus 로고    scopus 로고
    • Neutrophil extracellular traps capture and kill candida albicans yeast and hyphal forms
    • 16548892
    • Urban CF, Reichard U, Brinkmann V, Zychlinsky A. Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms. Cellular microbiology. 2006; 8(4):668-76. PMID: 16548892.
    • (2006) Cellular Microbiology , vol.8 , Issue.4 , pp. 668-676
    • Urban, C.F.1    Reichard, U.2    Brinkmann, V.3    Zychlinsky, A.4
  • 25
    • 77956245423 scopus 로고    scopus 로고
    • PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps
    • 20733033 Epub 2010/08/25. PubMed Central PMCID: PMC2931169
    • Li P, Li M, Lindberg MR, Kennett MJ, Xiong N, Wang Y. PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps. The Journal of experimental medicine. 2010; 207 (9):1853-62. Epub 2010/08/25. doi: 10.1084/jem.20100239 PMID: 20733033; PubMed Central PMCID: PMC2931169.
    • (2010) The Journal of Experimental Medicine , vol.207 , Issue.9 , pp. 1853-1862
    • Li, P.1    Li, M.2    Lindberg, M.R.3    Kennett, M.J.4    Xiong, N.5    Wang, Y.6
  • 26
    • 84879689982 scopus 로고    scopus 로고
    • Opposition between PKC isoforms regulates histone deimination and neutrophil extracellular chromatin release
    • 23430963 Epub 2013/02/23. PubMed Central PMCID: PMC3576869
    • Neeli I, Radic M. Opposition between PKC isoforms regulates histone deimination and neutrophil extracellular chromatin release. Frontiers in immunology. 2013; 4:38. Epub 2013/02/23. doi: 10.3389/fimmu. 2013.00038 PMID: 23430963; PubMed Central PMCID: PMC3576869.
    • (2013) Frontiers in Immunology , vol.4 , pp. 38
    • Neeli, I.1    Radic, M.2
  • 27
    • 84924059048 scopus 로고    scopus 로고
    • SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx
    • 25730848 Epub 2015/03/03. PubMed Central PMCID: PMC4352781
    • Douda DN, Khan MA, Grasemann H, Palaniyar N. SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx. Proceedings of the National Academy of Sciences of the United States of America. 2015; 112(9):2817-22. Epub 2015/03/03. doi: 10.1073/pnas.1414055112 PMID: 25730848; PubMed Central PMCID: PMC4352781.
    • (2015) Proceedings of the National Academy of Sciences of the United States of America , vol.112 , Issue.9 , pp. 2817-2822
    • Douda, D.N.1    Khan, M.A.2    Grasemann, H.3    Palaniyar, N.4
  • 28
    • 60849099332 scopus 로고    scopus 로고
    • Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation
    • 19153223 PubMed Central PMCID: PMC2654299
    • Wang Y, Li M, Stadler S, Correll S, Li P, Wang D, et al. Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. The Journal of cell biology. 2009; 184 (2):205-13. doi: 10.1083/jcb.200806072 PMID: 19153223; PubMed Central PMCID: PMC2654299.
    • (2009) The Journal of Cell Biology , vol.184 , Issue.2 , pp. 205-213
    • Wang, Y.1    Li, M.2    Stadler, S.3    Correll, S.4    Li, P.5    Wang, D.6
  • 29
    • 84856598960 scopus 로고    scopus 로고
    • Killing by neutrophil extracellular traps: Fact or folklore?
    • 22210873
    • Menegazzi R, Decleva E, Dri P. Killing by neutrophil extracellular traps: fact or folklore? Blood. 2012; 119(5):1214-6. doi: 10.1182/blood-2011-07-364604 PMID: 22210873.
    • (2012) Blood , vol.119 , Issue.5 , pp. 1214-1216
    • Menegazzi, R.1    Decleva, E.2    Dri, P.3
  • 30
    • 77958130620 scopus 로고    scopus 로고
    • Leishmania donovani promastigotes evade the antimicrobial activity of neutrophil extracellular traps
    • 20826753
    • Gabriel C, McMaster WR, Girard D, Descoteaux A. Leishmania donovani promastigotes evade the antimicrobial activity of neutrophil extracellular traps. J Immunol. 2010; 185(7):4319-27. doi: 10.4049/jimmunol.1000893 PMID: 20826753.
    • (2010) J Immunol. , vol.185 , Issue.7 , pp. 4319-4327
    • Gabriel, C.1    McMaster, W.R.2    Girard, D.3    Descoteaux, A.4
  • 31
    • 84880839043 scopus 로고    scopus 로고
    • In vitro resistance mechanisms of neisseria meningitidis against neutrophil extracellular traps
    • 23750848
    • Lappann M, Danhof S, Guenther F, Olivares-Florez S, Mordhorst IL, Vogel U. In vitro resistance mechanisms of Neisseria meningitidis against neutrophil extracellular traps. Molecular microbiology. 2013; 89 (3):433-49. doi: 10.1111/mmi.12288 PMID: 23750848.
    • (2013) Molecular Microbiology , vol.89 , Issue.3 , pp. 433-449
    • Lappann, M.1    Danhof, S.2    Guenther, F.3    Olivares-Florez, S.4    Mordhorst, I.L.5    Vogel, U.6
  • 32
    • 84861204482 scopus 로고    scopus 로고
    • IL-17RA signaling reduces inflammation and mortality during trypanosoma cruzi infection by recruiting suppressive IL-10-producing neutrophils
    • 22577359 PubMed Central PMCID: PMC3343119
    • Tosello Boari J, Amezcua Vesely MC, Bermejo DA, Ramello MC, Montes CL, Cejas H, et al. IL-17RA signaling reduces inflammation and mortality during Trypanosoma cruzi infection by recruiting suppressive IL-10-producing neutrophils. PLoS pathogens. 2012; 8(4):e1002658. doi: 10.1371/journal.ppat. 1002658 PMID: 22577359; PubMed Central PMCID: PMC3343119.
    • (2012) PLoS Pathogens , vol.8 , Issue.4 , pp. e1002658
    • Tosello Boari, J.1    Amezcua Vesely, M.C.2    Bermejo, D.A.3    Ramello, M.C.4    Montes, C.L.5    Cejas, H.6
  • 33
    • 34047259058 scopus 로고    scopus 로고
    • Capsule and D-alanylated lipoteichoic acids protect streptococcus pneumoniae against neutrophil extracellular traps
    • 17217430
    • Wartha F, Beiter K, Albiger B, Fernebro J, Zychlinsky A, Normark S, et al. Capsule and D-alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps. Cellular microbiology. 2007; 9(5):1162-71. PMID: 17217430.
    • (2007) Cellular Microbiology , vol.9 , Issue.5 , pp. 1162-1171
    • Wartha, F.1    Beiter, K.2    Albiger, B.3    Fernebro, J.4    Zychlinsky, A.5    Normark, S.6
  • 34
  • 35
    • 20044379765 scopus 로고    scopus 로고
    • The expression and roles of toll-like receptors in the biology of the human neutrophil
    • 15728244
    • Parker LC, Whyte MK, Dower SK, Sabroe I. The expression and roles of Toll-like receptors in the biology of the human neutrophil. Journal of leukocyte biology. 2005; 77(6):886-92. PMID: 15728244.
    • (2005) Journal of Leukocyte Biology , vol.77 , Issue.6 , pp. 886-892
    • Parker, L.C.1    Whyte, M.K.2    Dower, S.K.3    Sabroe, I.4
  • 36
    • 0141705297 scopus 로고    scopus 로고
    • Toll-like receptors stimulate human neutrophil function
    • 12829592
    • Hayashi F, Means TK, Luster AD. Toll-like receptors stimulate human neutrophil function. Blood. 2003; 102(7):2660-9. PMID: 12829592.
    • (2003) Blood , vol.102 , Issue.7 , pp. 2660-2669
    • Hayashi, F.1    Means, T.K.2    Luster, A.D.3
  • 37
    • 0035082873 scopus 로고    scopus 로고
    • DNA from protozoan parasites babesia bovis, Trypanosoma cruzi, and T. Brucei is mitogenic for B lymphocytes and stimulates macrophage expression of interleukin-12, tumor necrosis factor alpha, and nitric oxide
    • 11254571
    • Shoda LK, Kegerreis KA, Suarez CE, Roditi I, Corral RS, Bertot GM, et al. DNA from protozoan parasites Babesia bovis, Trypanosoma cruzi, and T. brucei is mitogenic for B lymphocytes and stimulates macrophage expression of interleukin-12, tumor necrosis factor alpha, and nitric oxide. Infection and immunity. 2001; 69(4):2162-71. PMID: 11254571.
    • (2001) Infection and Immunity , vol.69 , Issue.4 , pp. 2162-2171
    • Shoda, L.K.1    Kegerreis, K.A.2    Suarez, C.E.3    Roditi, I.4    Corral, R.S.5    Bertot, G.M.6
  • 38
    • 0035399862 scopus 로고    scopus 로고
    • Activation of toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite
    • 11418678
    • Campos MA, Almeida IC, Takeuchi O, Akira S, Valente EP, Procopio DO, et al. Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite. J Immunol. 2001; 167 (1):416-23. PMID: 11418678.
    • (2001) J Immunol. , vol.167 , Issue.1 , pp. 416-423
    • Campos, M.A.1    Almeida, I.C.2    Takeuchi, O.3    Akira, S.4    Valente, E.P.5    Procopio, D.O.6
  • 39
    • 78650916377 scopus 로고    scopus 로고
    • Nontypeable haemophilus influenzae initiates formation of neutrophil extracellular traps
    • 20956567 PubMed Central PMCID: PMC3019868
    • Juneau RA, Pang B, Weimer KE, Armbruster CE, Swords WE. Nontypeable Haemophilus influenzae initiates formation of neutrophil extracellular traps. Infection and immunity. 2011; 79(1):431-8. doi: 10.1128/IAI.00660-10 PMID: 20956567; PubMed Central PMCID: PMC3019868.
    • (2011) Infection and Immunity , vol.79 , Issue.1 , pp. 431-438
    • Juneau, R.A.1    Pang, B.2    Weimer, K.E.3    Armbruster, C.E.4    Swords, W.E.5
  • 40
    • 27144528203 scopus 로고    scopus 로고
    • The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung
    • 16237099
    • Wieland CW, Florquin S, Maris NA, Hoebe K, Beutler B, Takeda K, et al. The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung. J Immunol. 2005; 175(9):6042-9. PMID: 16237099.
    • (2005) J Immunol. , vol.175 , Issue.9 , pp. 6042-6049
    • Wieland, C.W.1    Florquin, S.2    Maris, N.A.3    Hoebe, K.4    Beutler, B.5    Takeda, K.6


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