An evaluation of the effect of pentoxifylline on blood pressure and myocardial oxidative status following intake of western diet

Clinical and Experimental Hypertension

Volumn 37, Issue 8, 2015, Pages 666-673

  Mayyas, Fadia ^a   Alzoubi, Karem H ^a   Al Taleb, Zahraa ^a  

^a JORDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Jordan)

Author keywords

Blood pressure; cardiac oxidative stress; pentoxifyllin; Western diet

Indexed keywords

CATALASE; CHOLESTEROL; GLUCOSE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PENTOXIFYLLINE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; ANTIOXIDANT; SCAVENGER;

ADULT; ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ENZYME ACTIVITY; HEART RATE; HEART WEIGHT; LIPID BLOOD LEVEL; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; SYSTOLIC BLOOD PRESSURE; WESTERN DIET; YOUNG ADULT; ANIMAL; CARDIAC MUSCLE; DISEASE MODEL; DRUG EFFECTS; HYPERTENSION; METABOLISM; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIOXIDANTS; BLOOD PRESSURE; DIET, WESTERN; DISEASE MODELS, ANIMAL; FREE RADICAL SCAVENGERS; GLUTATHIONE PEROXIDASE; HYPERTENSION; MALE; MYOCARDIUM; OXIDATIVE STRESS; PENTOXIFYLLINE; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 84947127894     PISSN: 10641963     EISSN: 15256006     Source Type: Journal    
DOI: 10.3109/10641963.2015.1047944     Document Type: Article

References (49)

1. Odermatt A. The Western-style diet: a major risk factor for impaired kidney function and chronic kidney disease. Am J Physiol Renal Physiol 2011; 301: F919-31
2. Suzanne M, Louis J. Causes of obesity. Abdom Imaging 2012; 37: 730-2
3. Cipollone F, Di Fabio S, Bucci M, Cicolini G. Angiotensin II blockade and total cardiovascular risk: beyond blood pressure reduction. High Blood Press Cardiovasc Prev 2008; 15: 245-53
4. Rodrigo R, Gonzalez J, Paoletto F. The role of oxidative stress in the pathophysiology of hypertension. Hypertens Res 2011; 34: 431-40
5. Bourgoin F, Bachelard H, Badeau M, et al. Endothelial and vascular dysfunctions and insulin resistance in rats fed a high-fat, high-sucrose diet. Am J Physiol Heart Circ Physiol 2008; 295: 1044-55
6. Dobrian A, Davies M, Schriver S, et al. Oxidative stress in a rat model of obesity-induced hypertension. Hypertens Res 2001; 37: 554-60
7. Matsuzawa N, Takamura T, Kurita S, et al. Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet. Hepatology 2007; 45: 1392-403
8. Sweazea K, Lekic M, Walker B. Comparison of mechanisms involved in impaired vascular reactivity between high sucrose and high fat diets in rats. Nutr Metab (Lond) 2010; 7: 48
9. Briones AM, Touyz RM. Oxidative stress and hypertension: current concepts. Curr Hypertens Rep 2010; 12: 135-42
10. Tilg H, Moschen AR. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol 2006; 6: 772-83
11. Guggilam A, Haque M, Kerut EK, et al. TNF-alpha blockade decreases oxidative stress in the paraventricular nucleus and attenuates sympathoexcitation in heart failure rats. Am J Physiol Heart Circ Physiol 2007; 293: H599-609
12. Alzoubi KH, Khabour OF, Tashtoush NH, et al. Evaluation of the effect of pentoxifylline on sleep-deprivation induced memory impairment. Hippocampus 2013; 23: 812-9
13. Wu KJ, Hsieh MT, Wu CR, et al. Green tea extract ameliorates learning and memory deficits in ischemic rats via its active component polyphenol epigallocatechin-3-gallate by modulation of oxidative stress and neuroinflammation. Evid Based Complement Alternat Med 2012; 2012: 163106
14. Bruno Rde B, Marques TF, Batista TM, et al. Pentoxifylline treatment improves neurological and neurochemical deficits in rats subjected to transient brain ischemia. Brain Res 2009; 1260: 55-64
15. Cunha GM, Bezerra PJ, Saldanha MD, et al. Pentoxifylline improves learning and memory in glutamate-lesioned rats. Pharmacol Biochem Behav 2000; 66: 687-94
16. Alzoubi KH, Khabour OF, Salah HA, Abu Rashid BE. The combined effect of sleep deprivation and Western diet on spatial learning and memory: role of BDNF and oxidative stress. J Mol Neurosci 2013; 50: 124-33
17. Alzoubi KH, Khabour OF, Salah HA, Hasan Z. Vitamin E prevents high-fat high-carbohydrates diet-induced memory impairment: the role of oxidative stress. Physiol Behav 2013; 119: 72-8
18. Alzoubi KH, Abdul-Razzak KK, Khabour OF, et al. Caffeine prevents cognitive impairment induced by chronic psychosocial stress and/or high fat-high carbohydrate diet. Behav Brain Res 2013; 237: 7-14
19. Gerges NZ, Aleisa AM, Alhaider AA, Alkadhi KA. Reduction of elevated arterial blood pressure in obese Zucker rats by inhibition of ganglionic long-term potentiation. Neuropharmacology 2002; 43: 1070-6
20. Alkadhi KA, Alzoubi KH, Aleisa AM, et al. Psychosocial stress-induced hypertension results from in vivo expression of long-term potentiation in rat sympathetic ganglia. Neurobiol Dis 2005; 20: 849-57
21. Alkadhi K, Otoom S, Tanner F, et al. Inhibition of ganglionic long-term potentiation decreases blood pressure in spontaneously hypertensive rats. Exp Biol Med (Maywood) 2001; 226: 1024-30
22. Aubin M, Lajoie C, Clement R, et al. Female rats fed a high-fat diet were associated with vascular dysfunction and cardiac fibrosis in the absence of overt obesity and hyperlipidemia: therapeutic potential of resveratrol. J Pharmacol Exp Ther 2008; 325: 961-8
23. Sengul O, Ferah I, Polat B, et al. Blockade of endothelin receptors with bosentan limits ischaemia/reperfusion-induced injury in rat ovaries. Eur J Obstet Gynecol Reprod Biol 2013; 170: 458-63
24. Xiaoyi L, Ya-min F, Gary G. Differential effects of specific amino acid restriction on glucose metabolism, reduction/oxidation status and mitochondrial damage in DU145 and PC3 prostate cancer cells. Oncol Lett 2011; 2: 349-55
25. Azhar A, El-Bassossy HM. Pentoxifylline alleviates cardiac ischemia and dysfunction following experimental angina in insulin resistance. PLoS One 2014; 9: e98281
26. Ihedioha J, Noel-Uneke O, Ihedioha T. Reference values for the serum lipid profile of albino rats (Rattus norvegicus) of varied ages and sexes. Comparative Clinical Pathology 2013; 22: 93-9
27. Garcia FA, Pinto SF, Cavalcante AF, et al. Pentoxifylline decreases glycemia levels and TNF-alpha, iNOS and COX-2 expressions in diabetic rat pancreas. Springerplus 2014; 3: 283
28. Salhiyyah K, Senanayake E, Abdel-Hadi M, et al. Pentoxifylline for intermittent claudication. Cochrane Database Syst Rev 2012; 1: CD005262
29. Wu J, Zhao MY, Zheng H, et al. Pentoxifylline alleviates high-fat diet-induced non-alcoholic steatohepatitis and early atherosclerosis in rats by inhibiting AGE and RAGE expression. Acta Pharmacol Sin 2010; 31: 1367-75
30. Sliwa K, Woodiwiss A, Libhaber E, et al. C-reactive protein predicts response to pentoxifylline in patients with idiopathic dilated cardiomyopathy. Eur J Heart Fail 2004; 6: 731-4
31. Bahrmann P, Hengst UM, Richartz BM, Figulla HR. Pentoxifylline in ischemic, hypertensive and idiopathic-dilated cardiomyopathy: effects on left-ventricular function, inflammatory cytokines and symptoms. Eur J Heart Fail 2004; 6: 195-201
32. Chrysohoou C, Panagiotakos DB, Pitsavos C, et al. The association between pre-hypertension status and oxidative stress markers related to atherosclerotic disease: the ATTICA study. Atherosclerosis 2007; 192: 169-76
33. Thiyagarajan R, Pal P, Pal GK, et al. Cardiovagal modulation, oxidative stress, and cardiovascular risk factors in prehypertensive subjects: cross-sectional study. Am J Hypertens 2007; 26: 850-7
34. Chobanian AV, Bakris GL, Black HR, et al. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003; 289: 2560-72
35. Yuzefovych L, Musiyenko S, Wilson G, Rachek L. Mitochondrial DNA damage and dysfunction, and oxidative stress are associated with endoplasmic reticulum stress, protein degradation and apoptosis in high fat diet-induced insulin resistance mice. PLoS One 2013; 8: e54059
36. Roberts C, Barnard R, Sindhu R, et al. A high-fat, refined-carbohydrate diet induces endothelial dysfunction and oxidant/antioxidant imbalance and depresses NOS protein expression. J Appl Physiol 2005; 98: 203-10
37. Alvarez M, Caldiz C, Fantinelli J, et al. Is cardiac hypertrophy in spontaneously hypertensive rats the cause or the consequence of oxidative stress? Hypertens Res 2008; 31: 1465-76
38. Singh R, Singh A, Singh M, Krishan P. Impact of obesity on hypertension-induced cardiac remodeling: role of oxidative stress and its modulation by gemfibrozil treatment in rats. Free Radic Biol Med 2011; 50: 363-70
39. Rennison JH, Van Wagoner DR. Impact of dietary fatty acids on cardiac arrhythmogenesis. Circ Arrhythm Electrophysiol 2009; 2: 460-9
40. Rennison JH, McElfresh TA, Okere IC, et al. Enhanced acyl-CoA dehydrogenase activity is associated with improved mitochondrial and contractile function in heart failure. Cardiovasc Res 2008; 79: 331-40
41. Chiu CJ, Liu S, Willett WC, et al. Informing food choices and health outcomes by use of the dietary glycemic index. Nutr Rev 2011; 69: 231-42
42. McIntyre TM, Hazen SL. Lipid oxidation and cardiovascular disease: introduction to a review series. Circ Res 2010; 107: 1167-9
43. Prasad K, Lee P. Suppression of hypercholesterolemic atherosclerosis by pentoxifylline and its mechanism. Atherosclerosis. 2007; 192: 313-22
44. Sohet FM, Neyrinck AM, Dewulf EM, et al. Lipid peroxidation is not a prerequisite for the development of obesity and diabetes in high-fat-fed mice. Br J Nutr 2009; 102: 462-9
45. Littlejohns B, Pasdois P, Duggan S, et al. Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury. PLoS One 2014; 9: e100579
46. Almario B, Wu S, Peng J, et al. Pentoxifylline and prevention of hyperoxia-induced lung-injury in neonatal rats. Pediatr Res 2012; 71: 583-9
47. Salo D, Pacifici R, Lin S, et al. Superoxide dismutase undergoes proteolysis and fragmentation following oxidative modification and inactivation. J Biol Chem 1990; 20: 11919-27
48. Birben E, Sahiner U, Sackesen C, et al. Oxidative stress and antioxidant defense. World Allergy Organ J 2012; 5: 9-19
49. Droge W. Free radicals in the physiological control of cell function. Physiol Rev 2002; 82: 47-95